Erythromycin Stearate (BioDeep_00000695575)
代谢物信息卡片
Erythromycin Stearate
化学式: C55H103NO15 (1017.7327328)
中文名称: 硬脂酸红霉素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCCCCCCCCCCCCC(=O)O.CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)O)(C)O
InChI: /m1./s1
描述信息
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
C784 - Protein Synthesis Inhibitor > C261 - Macrolide Antibiotic
C254 - Anti-Infective Agent > C258 - Antibiotic
D005765 - Gastrointestinal Agents
同义名列表
1 个代谢物同义名
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mumuni A Momoh, Emmanuel C Ossai, Omeje E Chidozie, Omenigbo O Precscila, Franklin C Kenechukwu, Kenneth O Ofokansi, Anthony A Attama, Kunle O Olobayo. A new lipid-based oral delivery system of erythromycin for prolong sustain release activity.
Materials science & engineering. C, Materials for biological applications.
2019 Apr; 97(?):245-253. doi:
10.1016/j.msec.2018.12.041. [PMID: 30678909] - H Yoshida, T Furuta. [Tissue penetration properties of macrolide antibiotics--comparative tissue distribution of erythromycin-stearate, clarithromycin, roxithromycin and azithromycin in rats].
The Japanese journal of antibiotics.
1999 Jul; 52(7):497-503. doi:
. [PMID: 10516929] - W A Coulter, J G McGimpsey, A Coffey, J Strawbridge, G J Linden. Dental anxiety and the absorption of orally administered erythromycin stearate.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
1995 Dec; 80(6):660-5. doi:
10.1016/s1079-2104(05)80247-1. [PMID: 8680971] - V Thamlikitkul, S Kobwanthanakun, S Pruksachatvuthi, R Lertluknithi. Pharmacokinetics of rheumatic fever prophylaxis regimens.
The Journal of international medical research.
1992 Feb; 20(1):20-6. doi:
10.1177/030006059202000103. [PMID: 1568517] - R K Tuominen, R Lehtinen, J Peltola, R Wikberg, A Gordin, P Kokkonen, P Pohto. Penetration of erythromycin into periapical lesions after repeated doses of erythromycin acistrate and erythromycin stearate: a pilot study.
Oral surgery, oral medicine, and oral pathology.
1991 Jun; 71(6):684-8. doi:
10.1016/0030-4220(91)90274-g. [PMID: 2062521] - A M Sefton, J P Maskell, C Kerawala, H Cannell, A Seymour, Z M Sun, J D Williams. Comparative efficacy and tolerance of erythromycin and josamycin in the prevention of bacteraemia following dental extraction.
The Journal of antimicrobial chemotherapy.
1990 Jun; 25(6):975-84. doi:
10.1093/jac/25.6.975. [PMID: 2196261] - S S Kaukoranta-Tolvanen, O V Renkonen, A Gordin, L Tamm, P T Männistö. Effect of erythromycin acistrate and erythromycin stearate on human colonic microflora.
Scandinavian journal of infectious diseases.
1989; 21(6):717-20. doi:
10.3109/00365548909021702. [PMID: 2617212] - M De Bernardi, F Feletti, G Gazzani, G B Fregnan. Human pharmacokinetics of erythromycin propionate-N-acetylcysteinate: comparative evaluation with erythromycin stearate and N-acetylcysteine.
International journal of clinical pharmacology, therapy, and toxicology.
1988 Sep; 26(9):444-7. doi:
NULL. [PMID: 3198299] - A Gordin, P T Männistö, R Antikainen, S Savolainen, J Ylikoski, P Kokkonen, V Rauramaa. Concentrations of erythromycin, 2'-acetyl erythromycin, and their anhydro forms in plasma and tonsillar tissue after repeated dosage of erythromycin stearate and erythromycin acistrate.
Antimicrobial agents and chemotherapy.
1988 Jul; 32(7):1019-24. doi:
10.1128/aac.32.7.1019. [PMID: 3190191] - S Savolainen, P T Männistö, A Gordin, R Antikainen, H Haataja, R K Tuominen, J Ylikoski. Tonsillar penetration of erythromycin and its 2'-acetyl ester in patients with chronic tonsillitis.
The Journal of antimicrobial chemotherapy.
1988 Jun; 21 Suppl D(?):73-84. doi:
10.1093/jac/21.suppl_d.73. [PMID: 3391878] - G Ricevuti, D Pasotti, A Mazzone, G Gazzani, G B Fregnan. Serum, sputum and bronchial concentrations of erythromycin in chronic bronchitis after single and multiple treatments with either propionate-N-acetylcysteinate or stearate erythromycin.
Chemotherapy.
1988; 34(5):374-9. doi:
10.1159/000238595. [PMID: 3180905] - V M Venho, E S Palva, K Konno, E Stenfors. The value of comparative bioavailability studies of marketed drugs in drug control. An example with erythromycin stearate.
Methods and findings in experimental and clinical pharmacology.
1987 Jul; 9(7):445-7. doi:
NULL. [PMID: 3683018] - D C Shanson, S Akash, M Harris, M Tadayon. Erythromycin stearate, 1.5 g, for the oral prophylaxis of streptococcal bacteraemia in patients undergoing dental extraction: efficacy and tolerance.
The Journal of antimicrobial chemotherapy.
1985 Jan; 15(1):83-90. doi:
10.1093/jac/15.1.83. [PMID: 3882657] - A Schreiner, A Digranes. Absorption of erythromycin stearate and enteric-coated erythromycin base after a single oral dose immediately before breakfast.
Infection.
1984 Sep; 12(5):345-8. doi:
10.1007/bf01651150. [PMID: 6511088] - D C Shanson, P Tidbury, W R McNabb, M Tadayon. The pharmacokinetics and tolerance of oral erythromycin stearate compared with erythromycin ethylsuccinate: implications for preventing endocarditis.
The Journal of antimicrobial chemotherapy.
1984 Aug; 14(2):157-63. doi:
10.1093/jac/14.2.157. [PMID: 6334070] - R Anderson, A C Fernandes, H E Eftychis. Studies on the effects of ingestion of a single 500 mg oral dose of erythromycin stearate on leucocyte motility and transformation and on release in vitro of prostaglandin E2 by stimulated leucocytes.
The Journal of antimicrobial chemotherapy.
1984 Jul; 14(1):41-50. doi:
10.1093/jac/14.1.41. [PMID: 6592163] - H Francis, A Tyndall, J Webb. Severe vascular spasm due to erythromycin-ergotamine interaction.
Clinical rheumatology.
1984 Jun; 3(2):243-6. doi:
10.1007/bf02030764. [PMID: 6236021] - R A Walstad, K B Hellum. Penetration of erythromycin in respiratory tract infections.
Acta oto-laryngologica. Supplementum.
1984; 407(?):50-4. doi:
10.3109/00016488409124965. [PMID: 6333775] - T B Tjandramaga, A Van Hecken, A Mullie, R Verbesselt, P J De Schepper, L Verbist, K Josefsson. Relative bioavailability of enteric coated pellets, stearate and ethylsuccinate formulations of erythromycin.
Pharmacology.
1984; 29(6):305-11. doi:
10.1159/000138029. [PMID: 6334320] - H G Robson, P P Shah, R G Lalonde, L Hayes, V M Senikas. Comparison of rosaramicin and erythromycin stearate for treatment of cervical infection with Chlamydia trachomatis.
Sexually transmitted diseases.
1983 Jul; 10(3):130-4. doi:
10.1097/00007435-198307000-00006. [PMID: 6648747] - D C Warhurst, B L Robinson, W Peters. The blood schizontocidal action of erythromycin against Plasmodium knowlesi infections in Macaca mulatta.
Annals of tropical medicine and parasitology.
1983 Jun; 77(3):231-7. doi:
10.1080/00034983.1983.11811703. [PMID: 6625724] - B M Stults, J Felice-Johnson, M D Higbee, K Hardigan. Effect of erythromycin stearate on serum theophylline concentration in patients with chronic obstructive lung disease.
Southern medical journal.
1983 Jun; 76(6):714-8. doi:
10.1097/00007611-198306000-00008. [PMID: 6857302] - P A Quinn, A B Shewchuk, J Shuber, K I Lie, E Ryan, M L Chipman, D M Nocilla. Efficacy of antibiotic therapy in preventing spontaneous pregnancy loss among couples colonized with genital mycoplasmas.
American journal of obstetrics and gynecology.
1983 Jan; 145(2):239-44. doi:
10.1016/0002-9378(83)90499-4. [PMID: 6849358] - M Ducci, V Scalori, M del Tacca, G Soldani, C Bernardini, E Grothe, A Bertelli. The pharmacokinetics of two erythromycin esters in plasma and in saliva following oral administration in humans.
International journal of clinical pharmacology, therapy, and toxicology.
1981 Nov; 19(11):494-7. doi:
NULL. [PMID: 7298242] - A Iliopoulou, R N Thin, P Turner. Fluorimetric and microbiological assays of erythromycin concentrations in plasma and vaginal washings.
The British journal of venereal diseases.
1981 Aug; 57(4):263-7. doi:
10.1136/sti.57.4.263. [PMID: 7272705] - D Clayton, A Leslie. The bioavailability of erythromycin stearate versus enteric-coated erythromycin base when taken immediately before and after food.
The Journal of international medical research.
1981; 9(6):470-7. doi:
10.1177/030006058100900608. [PMID: 7319133] - J G McGimpsey, C H Webb, P H McCrea. Comparison of serum erythromycin concentration following administration of 100 mg erythromycin ethyl succinate intramuscularly and 500 mg erythromycin stearate orally.
International journal of oral surgery.
1981; 10(Suppl 1):198-202. doi:
NULL. [PMID: 6807878]