Premarin (BioDeep_00000694287)
PANOMIX_OTCML-2023
代谢物信息卡片
Estrone sulfate sodium
化学式: C18H21NaO5S (372.1007)
中文名称: 雌酮3-硫酸钠盐
谱图信息:
最多检出来源 Chinese Herbal Medicine(otcml) 93.55%
分子结构信息
SMILES: CC12CCC3C(C1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)[O-].[Na+]
InChI: /q
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
Estrone sulfate, a biologically inactive form of estrogen, is a major circulating plasma estrogen that is converted into the biologically active estrogen, estrone (E1) by steroid sulfatase (STS). Estrone sulfate can be used for the research of breast cancer[1][2].
同义名列表
3 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:8389
- KEGGdrug: D00312
- PubChem: 23667301
- ChEMBL: CHEMBL2106240
- MeSH: Estrogens, Conjugated (USP)
- CAS: 438-67-5
- medchemexpress: HY-113293B
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Shengwei Zhang, Jing Li, Yanxia Li, Linshu Jiang, Yan Zhao, Xiaoman Jiang, Xuelian Zhang, Wenzhuo Shi. Assimilation behaviors and metabolite formations of estrone sulfate sodium (E1-3S) and 17β-estradiol-3-O-sulfate sodium (E2-3S) in the wheat.
Journal of environmental management.
2023 Jul; 345(?):118666. doi:
10.1016/j.jenvman.2023.118666. [PMID: 37506444] - Patrice Dufour, Justine Courtois, Ysaline Seynaeve, Stéphanie Peeters, Caroline Le Goff, Etienne Cavalier, Jérôme Ponthier. Development and validation of a liquid chromatography coupled to mass spectrometer (LC-MS) method for the simultaneous quantification of estrone-3-sulfate, progesterone, estrone and estradiol in serum of mares and American bisons.
Research in veterinary science.
2021 May; 136(?):343-350. doi:
10.1016/j.rvsc.2021.03.014. [PMID: 33770524] - Julian Peter Müller, Lena Keufgens, Dirk Gründemann. Hyperosmolarity stimulates transporter-mediated insertion of estrone sulfate into the plasma membrane, but inhibits the uptake by SLC10A1 (NTCP).
Biochemical pharmacology.
2021 04; 186(?):114484. doi:
10.1016/j.bcp.2021.114484. [PMID: 33617845] - Jinghui Zhang, Guofeng You. Peptide Hormone Insulin Regulates Function, Expression, and SUMOylation of Organic Anion Transporter 3.
The AAPS journal.
2021 03; 23(2):41. doi:
10.1208/s12248-021-00575-z. [PMID: 33709304] - Carina Ankarberg-Lindgren, Mats X Andersson, Jovanna Dahlgren. Determination of estrone sulfate, testosterone, androstenedione, DHEAS, cortisol, cortisone, and 17α-hydroxyprogesterone by LC-MS/MS in children and adolescents.
Scandinavian journal of clinical and laboratory investigation.
2020 Dec; 80(8):672-680. doi:
10.1080/00365513.2020.1829699. [PMID: 33258387] - Yusuke Masuo, Ken-Ichi Fujita, Kenji Mishiro, Natsumi Seba, Tatsuya Kogi, Hidenori Okumura, Natsumi Matsumoto, Munetaka Kunishima, Yukio Kato. 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients.
Drug metabolism and pharmacokinetics.
2020 Dec; 35(6):555-562. doi:
10.1016/j.dmpk.2020.09.001. [PMID: 33191090] - Krystal Thomas-White, Susanne Taege, Roberto Limeira, Cynthia Brincat, Cara Joyce, Evann E Hilt, Laura Mac-Daniel, Katherine A Radek, Linda Brubaker, Elizabeth R Mueller, Alan J Wolfe. Vaginal estrogen therapy is associated with increased Lactobacillus in the urine of postmenopausal women with overactive bladder symptoms.
American journal of obstetrics and gynecology.
2020 11; 223(5):727.e1-727.e11. doi:
10.1016/j.ajog.2020.08.006. [PMID: 32791124] - Alli Tikkanen, Estelle Pierrot, Feng Deng, Virginia Barras Sánchez, Marja Hagström, Jan B Koenderink, Heidi Kidron. Food Additives as Inhibitors of Intestinal Drug Transporter OATP2B1.
Molecular pharmaceutics.
2020 10; 17(10):3748-3758. doi:
10.1021/acs.molpharmaceut.0c00507. [PMID: 32845645] - Kara L Marlatt, Dragana Lovre, Robbie A Beyl, Chandra R Tate, Evelyn K Hayes, Charles F Burant, Eric Ravussin, Franck Mauvais-Jarvis. Effect of conjugated estrogens and bazedoxifene on glucose, energy and lipid metabolism in obese postmenopausal women.
European journal of endocrinology.
2020 Oct; 183(4):439-452. doi:
10.1530/eje-20-0619. [PMID: 32698159] - Wataru Iwasaki, Chiwa Kataoka, Kazuyuki Sawadaishi, Keitaro Suyama, Nobutomo Morita, Masaya Miyazaki. A Simple, Low Cost, Sensitive, and Portable Electrochemical Immunochromatography Sensing Device to Measure Estrone-3-Sulfate.
Sensors (Basel, Switzerland).
2020 Aug; 20(17):. doi:
10.3390/s20174781. [PMID: 32847124] - X Liu, T Schwarz, M Murawski, C Tayade, R Kridli, A M Prieto Granados, C Sharma, P M Bartlewski. Measurements of circulating progesterone and estrone sulfate concentrations as a diagnostic and prognostic tool in porcine pregnancy revisited.
Domestic animal endocrinology.
2020 04; 71(?):106402. doi:
10.1016/j.domaniend.2019.106402. [PMID: 31972516] - Carien van der Berg, Gerda Venter, Francois H van der Westhuizen, Elardus Erasmus. Development and validation of LC-ESI-MS/MS methods for quantification of 27 free and conjugated estrogen-related metabolites.
Analytical biochemistry.
2020 02; 590(?):113531. doi:
10.1016/j.ab.2019.113531. [PMID: 31805274] - Zsuzsanna Suba. Prevention and therapy of COVID-19 via exogenous estrogen treatment for both male and female patients.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques.
2020; 23(1):75-85. doi:
10.18433/jpps31069. [PMID: 32324533] - Tämer El Saadany, Belle van Rosmalen, Zhibo Gai, Christian Hiller, Joanne Verheij, Bruno Stieger, Thomas van Gulik, Michele Visentin, Gerd A Kullak-Ublick. microRNA-206 modulates the hepatic expression of the organic anion-transporting polypeptide 1B1.
Liver international : official journal of the International Association for the Study of the Liver.
2019 12; 39(12):2350-2359. doi:
10.1111/liv.14212. [PMID: 31408569] - Hiroshi Miura, Tatsuya Yamazaki, Motohiro Kikuchi, Minoru Sakaguchi. Plasma steroid hormone concentrations and their relationships in Suffolk ewes during gestation and parturition.
Animal science journal = Nihon chikusan Gakkaiho.
2019 Nov; 90(11):1426-1431. doi:
10.1111/asj.13286. [PMID: 31486265] - Carol J Fabian, Lauren Nye, Kandy R Powers, Jennifer L Nydegger, Amy L Kreutzjans, Teresa A Phillips, Trina Metheny, Onalisa Winblad, Carola M Zalles, Christy R Hagan, Merit L Goodman, Byron J Gajewski, Devin C Koestler, Prabhakar Chalise, Bruce F Kimler. Effect of Bazedoxifene and Conjugated Estrogen (Duavee) on Breast Cancer Risk Biomarkers in High-Risk Women: A Pilot Study.
Cancer prevention research (Philadelphia, Pa.).
2019 10; 12(10):711-720. doi:
10.1158/1940-6207.capr-19-0315. [PMID: 31420361] - Gwenaëlle Conseil, May Arama-Chayoth, Yossi Tsfadia, Susan P C Cole. Structure-guided probing of the leukotriene C4 binding site in human multidrug resistance protein 1 (MRP1; ABCC1).
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2019 10; 33(10):10692-10704. doi:
10.1096/fj.201900140r. [PMID: 31268744] - Gerhard Schuler, Angelika W Bernhardt-Welte, Klaus Failing, Bernd Hoffmann. [Concentrations of testosterone, estrone and estrone sulfate in peripheral blood of donkey stallions in relation to season].
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere.
2019 Oct; 47(5):294-297. doi:
10.1055/a-0988-0964. [PMID: 31634940] - Ye Feng, Yang Xie, Meishu Xu, Linhao Li, Kyle W Selcer, Patrick J Oberly, Samuel M Poloyac, Hongbing Wang, Chengjiang Li, Fengqin Dong, Chaohui Yu, Wen Xie. Hepatic steroid sulfatase critically determines estrogenic activities of conjugated equine estrogens in human cells in vitro and in mice.
The Journal of biological chemistry.
2019 08; 294(32):12112-12121. doi:
10.1074/jbc.ra119.009181. [PMID: 31217279] - Shiva Pratap Singh, Natesan Ramachandran, Nandini Sharma, Anil Kumar Goel, Kumaresan Gururaj, Suresh Dinkar Kharche. Temporal changes in plasma profile of pregnancy-associated glycoprotein, progesterone and estrone sulfate associated with fetal number during early- and mid-pregnancy in goats.
Animal reproduction science.
2019 Jun; 205(?):115-125. doi:
10.1016/j.anireprosci.2019.04.010. [PMID: 31040054] - A Rehailia-Blanchard, M Y He, C Rancoule, É Guillaume, J-B Guy, N Vial, A Nivet, H Orliac, C Chargari, N Magné. [Medical prevention and treatment of radiation-induced urological and nephrological complications].
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique.
2019 Apr; 23(2):151-160. doi:
10.1016/j.canrad.2018.05.007. [PMID: 30898418] - Tipwadee Bunprajun, Chaowalit Yuajit, Rattikarn Noitem, Varanuj Chatsudthipong. Exhaustive exercise decreases renal organic anion transporter 3 function.
The journal of physiological sciences : JPS.
2019 Mar; 69(2):245-251. doi:
10.1007/s12576-018-0641-5. [PMID: 30284192] - B A Ball, G M Davolli, A Esteller-Vico, B O Fleming, M A A Wynn, A J Conley. Inhibin-A and Inhibin-B in stallions: Seasonal changes and changes after down-regulation of the hypothalamic-pituitary-gonadal axis.
Theriogenology.
2019 Jan; 123(?):108-115. doi:
10.1016/j.theriogenology.2018.09.036. [PMID: 30296651] - Anima M Schäfer, Thomas Bock, Henriette E Meyer Zu Schwabedissen. Establishment and Validation of Competitive Counterflow as a Method To Detect Substrates of the Organic Anion Transporting Polypeptide 2B1.
Molecular pharmaceutics.
2018 12; 15(12):5501-5513. doi:
10.1021/acs.molpharmaceut.8b00631. [PMID: 30380886] - Bhagu R Bhavnani, Anthony Cecutti, Alan Gerulath, Allan C Woolever, Mauricio Berco. Comparison of the antioxidant effects of equine estrogens, red wine components, vitamin E, and probucol on low-density lipoprotein oxidation in postmenopausal women.
Menopause (New York, N.Y.).
2018 11; 25(11):1214-1223. doi:
10.1097/gme.0000000000001222. [PMID: 30358716] - Jacques Emile Rioux, M Corinne Devlin, Morrie M Gelfand, Wilfred M Steinberg, Douglas S Hepburn. 17β-estradiol vaginal tablet versus conjugated equine estrogen vaginal cream to relieve menopausal atrophic vaginitis.
Menopause (New York, N.Y.).
2018 11; 25(11):1208-1213. doi:
10.1097/gme.0000000000001220. [PMID: 30358715] - Liisa A M Galea, Meighen M Roes, Christina J Dimech, Carmen Chow, Rand Mahmoud, Stephanie E Lieblich, Paula Duarte-Guterman. Premarin has opposing effects on spatial learning, neural activation, and serum cytokine levels in middle-aged female rats depending on reproductive history.
Neurobiology of aging.
2018 10; 70(?):291-307. doi:
10.1016/j.neurobiolaging.2018.06.030. [PMID: 30056312] - Jae Hee Kang, Bernard A Rosner, Janey L Wiggs, Louis R Pasquale. Sex hormone levels and risk of primary open-angle glaucoma in postmenopausal women.
Menopause (New York, N.Y.).
2018 10; 25(10):1116-1123. doi:
10.1097/gme.0000000000001120. [PMID: 29787481] - Celio Ferreira, Paul Hagen, Melanie Stern, Janine Hussner, Uwe Zimmermann, Markus Grube, Henriette E Meyer Zu Schwabedissen. The scaffold protein PDZK1 modulates expression and function of the organic anion transporting polypeptide 2B1.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.
2018 Jul; 120(?):181-190. doi:
10.1016/j.ejps.2018.05.006. [PMID: 29752999] - K Satué, M Marcilla, P Medica, A Ferlazzo, E Fazio. Sequential concentrations of placental growth factor and haptoglobin, and their relation to oestrone sulphate and progesterone in pregnant Spanish Purebred mare.
Theriogenology.
2018 Jul; 115(?):77-83. doi:
10.1016/j.theriogenology.2018.04.033. [PMID: 29730538] - Henriette E Meyer Zu Schwabedissen, Celio Ferreira, Anima M Schaefer, Mouhssin Oufir, Isabell Seibert, Matthias Hamburger, Rommel G Tirona. Thyroid Hormones Are Transport Substrates and Transcriptional Regulators of Organic Anion Transporting Polypeptide 2B1.
Molecular pharmacology.
2018 07; 94(1):700-712. doi:
10.1124/mol.117.111161. [PMID: 29735582] - Karen Lee Ann Chen, Xiaoji Liu, Yiru Chen Zhao, Kadriye Hieronymi, Gianluigi Rossi, Loretta Sue Auvil, Michael Welge, Colleen Bushell, Rebecca Lee Smith, Kathryn E Carlson, Sung Hoon Kim, John A Katzenellenbogen, Michael Joseph Miller, Zeynep Madak-Erdogan. Long-Term Administration of Conjugated Estrogen and Bazedoxifene Decreased Murine Fecal β-Glucuronidase Activity Without Impacting Overall Microbiome Community.
Scientific reports.
2018 05; 8(1):8166. doi:
10.1038/s41598-018-26506-1. [PMID: 29802368] - Erkka Järvinen, Feng Deng, Heidi Kidron, Moshe Finel. Efflux transport of estrogen glucuronides by human MRP2, MRP3, MRP4 and BCRP.
The Journal of steroid biochemistry and molecular biology.
2018 04; 178(?):99-107. doi:
10.1016/j.jsbmb.2017.11.007. [PMID: 29175180] - Rie Iijima, Tomoki Watanabe, Kan'ichiro Ishiuchi, Takashi Matsumoto, Junko Watanabe, Toshiaki Makino. Interactions between crude drug extracts used in Japanese traditional Kampo medicines and organic anion-transporting polypeptide 2B1.
Journal of ethnopharmacology.
2018 Mar; 214(?):153-159. doi:
10.1016/j.jep.2017.12.016. [PMID: 29248449] - Jinghui Zhang, Chenchang Liu, Guofeng You. AG490, a JAK2-specific inhibitor, downregulates the expression and activity of organic anion transporter-3.
Journal of pharmacological sciences.
2018 Mar; 136(3):142-148. doi:
10.1016/j.jphs.2018.01.006. [PMID: 29487013] - S Caceres, B Monsalve, L Peña, P J de Andres, A Alonso-Diez, M J Illera, W A Woodward, J M Reuben, G Silvan, J C Illera. In vitro and in vivo effect of flutamide on steroid hormone secretion in canine and human inflammatory breast cancer cell lines.
Veterinary and comparative oncology.
2018 Mar; 16(1):148-158. doi:
10.1111/vco.12324. [PMID: 28589573] - Yuyong Ke, Alain Bélanger, Jean-Nicolas Simard, Renaud Gonthier, Céline Martel, Mario Vaillancourt, Fernand Labrie. Concentration range of serum sex steroids in normal postmenopausal women and those with diagnosis of vulvovaginal atrophy.
Menopause (New York, N.Y.).
2018 03; 25(3):293-300. doi:
10.1097/gme.0000000000000993. [PMID: 29206779] - Haoxun Wang, Chenchang Liu, Guofeng You. The activity of organic anion transporter-3: Role of dexamethasone.
Journal of pharmacological sciences.
2018 Feb; 136(2):79-85. doi:
10.1016/j.jphs.2017.12.011. [PMID: 29422382] - Yugo Hamada, Kenji Ikemura, Takuya Iwamoto, Masahiro Okuda. Stereoselective Inhibition of Renal Basolateral Human Organic Anion Transporter 3 by Lansoprazole Enantiomers.
Pharmacology.
2018; 101(3-4):176-183. doi:
10.1159/000485920. [PMID: 29353278] - Jixia Liu, Ran Zhao, Zhan Ye, Alexander J Frey, Emily R Schriver, Nathaniel W Snyder, Scott J Hebbring. Relationship of SULT1A1 copy number variation with estrogen metabolism and human health.
The Journal of steroid biochemistry and molecular biology.
2017 11; 174(?):169-175. doi:
10.1016/j.jsbmb.2017.08.017. [PMID: 28867356] - Haoxun Wang, Guofeng You. SGK1/Nedd4-2 signaling pathway regulates the activity of human organic anion transporters 3.
Biopharmaceutics & drug disposition.
2017 Nov; 38(8):449-457. doi:
10.1002/bdd.2085. [PMID: 28608480] - Birgitta C Burckhardt, Maja Henjakovic, Yohannes Hagos, Gerhard Burckhardt. Differential Interaction of Dantrolene, Glafenine, Nalidixic Acid, and Prazosin with Human Organic Anion Transporters 1 and 3.
The Journal of pharmacology and experimental therapeutics.
2017 09; 362(3):450-458. doi:
10.1124/jpet.117.241406. [PMID: 28630284] - Ashraf H Ahmed, Richard D Gordon, Gregory Ward, Martin Wolley, Brett C McWhinney, Jacobus P Ungerer, Michael Stowasser. Effect of Combined Hormonal Replacement Therapy on the Aldosterone/Renin Ratio in Postmenopausal Women.
The Journal of clinical endocrinology and metabolism.
2017 07; 102(7):2329-2334. doi:
10.1210/jc.2016-3851. [PMID: 28379474] - Byung Koo Yoon, Dong Yun Lee, Man Chul Park, Soo Hyun Cho, Hyoung Moo Park, Young Min Choi. Effects of Combination Therapy of Alendronate and Hormonal Therapy on Bone Mineral Density in Postmenopausal Korean Women: Multicenter, Randomized Controlled Clinical Trial.
Journal of Korean medical science.
2017 Jun; 32(6):992-998. doi:
10.3346/jkms.2017.32.6.992. [PMID: 28480658] - Dahima Cintron, John P Beckman, Kent R Bailey, Brian D Lahr, Muthuvel Jayachandran, Virginia M Miller. Plasma orexin A levels in recently menopausal women during and 3 years following use of hormone therapy.
Maturitas.
2017 May; 99(?):59-65. doi:
10.1016/j.maturitas.2017.01.016. [PMID: 28364870] - Emily J Johnson, Christina S Won, Kathleen Köck, Mary F Paine. Prioritizing pharmacokinetic drug interaction precipitants in natural products: application to OATP inhibitors in grapefruit juice.
Biopharmaceutics & drug disposition.
2017 Apr; 38(3):251-259. doi:
10.1002/bdd.2061. [PMID: 28032362] - Peter Skwara, Edgar Schömig, Dirk Gründemann. A novel mode of operation of SLC22A11: Membrane insertion of estrone sulfate versus translocation of uric acid and glutamate.
Biochemical pharmacology.
2017 Mar; 128(?):74-82. doi:
10.1016/j.bcp.2016.12.020. [PMID: 28027879] - Karen Lee Ann Chen, Yiru Chen Zhao, Kadriye Hieronymi, Brandi Patricia Smith, Zeynep Madak-Erdogan. Bazedoxifene and conjugated estrogen combination maintains metabolic homeostasis and benefits liver health.
PloS one.
2017; 12(12):e0189911. doi:
10.1371/journal.pone.0189911. [PMID: 29267318] - G M Davolli, B A Ball, A Esteller-Vico, A N J Claes, I F Canisso, C E Fedorka, E M Woodward, M H T Troedsson, E L Squires. Reversible downregulation of the hypothalamic-pituitary-gonadal axis in stallions with a novel GnRH antagonist.
Theriogenology.
2016 Dec; 86(9):2272-2280. doi:
10.1016/j.theriogenology.2016.07.021. [PMID: 27570103] - Nisreen Hoosain, Brendon Pearce, Clifford Jacobs, Mongi Benjeddou. Mapping SLCO1B1 Genetic Variation for Global Precision Medicine in Understudied Regions in Africa: A Focus on Zulu and Cape Admixed Populations.
Omics : a journal of integrative biology.
2016 09; 20(9):546-54. doi:
10.1089/omi.2016.0115. [PMID: 27631194] - T Ebihara, T Takeuchi, Y Moriya, Y Tagawa, T Kondo, T Moriwaki, S Asahi. Characterization of Transporters in the Hepatic Uptake of TAK-475 M-I, a Squalene Synthase Inhibitor, in Rats and Humans.
Drug research.
2016 Jun; 66(6):316-23. doi:
10.1055/s-0035-1569441. [PMID: 27011383] - Rebekah McCurdy, Xuezhi Jiang, Thomas B Clarkson, Matthew Nudy, Peter F Schnatz. Vitamin D and conjugated equine estrogen: the association with coronary artery atherosclerosis in cynomolgus monkeys.
Menopause (New York, N.Y.).
2016 05; 23(5):481-7. doi:
10.1097/gme.0000000000000582. [PMID: 26886883] - R Arlanov, T Lang, G Jedlitschky, E Schaeffeler, T Ishikawa, M Schwab, A T Nies. Functional characterization of common protein variants in the efflux transporter ABCC11 and identification of T546M as functionally damaging variant.
The pharmacogenomics journal.
2016 Apr; 16(2):193-201. doi:
10.1038/tpj.2015.27. [PMID: 25896536] - Ikuko Kato, Rowan T Chlebowski, Lifang Hou, Jean Wactawski-Wende, Roberta M Ray, Judith Abrams, Cathryn Bock, Pinkal Desai, Michael S Simon. Menopausal estrogen therapy and non-Hodgkin's lymphoma: A post-hoc analysis of women's health initiative randomized clinical trial.
International journal of cancer.
2016 Feb; 138(3):604-11. doi:
10.1002/ijc.29819. [PMID: 26365326] - Christian Bjerregaard-Olesen, Mandana Ghisari, Lisbeth S Kjeldsen, Maria Wielsøe, Eva C Bonefeld-Jørgensen. Estrone sulfate and dehydroepiandrosterone sulfate: Transactivation of the estrogen and androgen receptor.
Steroids.
2016 Jan; 105(?):50-8. doi:
10.1016/j.steroids.2015.11.009. [PMID: 26666359] - Fengjiao Wen, Meizhi Shi, Jialin Bian, Hongjian Zhang, Chunshan Gui. Identification of natural products as modulators of OATP2B1 using LC-MS/MS to quantify OATP-mediated uptake.
Pharmaceutical biology.
2016; 54(2):293-302. doi:
10.3109/13880209.2015.1034326. [PMID: 25858254] - Michaella J Levy, Michael T Boyne, Sarah Rogstad, David J Skanchy, Xiaohui Jiang, Ilan Geerlof-Vidavsky. Marketplace Analysis of Conjugated Estrogens: Determining the Consistently Present Steroidal Content with LC-MS.
The AAPS journal.
2015 Nov; 17(6):1438-45. doi:
10.1208/s12248-015-9805-x. [PMID: 26242210] - Karen L Shea, Kathleen M Gavin, Edward L Melanson, Ellie Gibbons, Anne Stavros, Pamela Wolfe, John M Kittelson, Sheryl F Vondracek, Robert S Schwartz, Margaret E Wierman, Wendy M Kohrt. Body composition and bone mineral density after ovarian hormone suppression with or without estradiol treatment.
Menopause (New York, N.Y.).
2015 Oct; 22(10):1045-52. doi:
10.1097/gme.0000000000000430. [PMID: 25783468] - F L Queiroga, D Pérez-Alenza, A González-Gil, G Silván, L Peña, J C Illera. Serum and Tissue Steroid Hormone Levels in Canine Mammary Tumours: Clinical and Prognostic Implications.
Reproduction in domestic animals = Zuchthygiene.
2015 Oct; 50(5):858-65. doi:
10.1111/rda.12597. [PMID: 26332137] - Saki Noguchi, Tomohiro Nishimura, Ayasa Fujibayashi, Tetsuo Maruyama, Masatoshi Tomi, Emi Nakashima. Organic Anion Transporter 4-Mediated Transport of Olmesartan at Basal Plasma Membrane of Human Placental Barrier.
Journal of pharmaceutical sciences.
2015 Sep; 104(9):3128-35. doi:
10.1002/jps.24434. [PMID: 25820021] - Ahmed Mahmoud Abdelbary, A Aref El-Dessoukey, Amr M Massoud, Ayman S Moussa, Ahmed S Zayed, Mohame G Elsheikh, Waleed Ghoneima, Rana Abdella, Mohamed Yousef. Combined Vaginal Pelvic Floor Electrical Stimulation (PFS) and Local Vaginal Estrogen for Treatment of Overactive Bladder (OAB) in Perimenopausal Females. Randomized Controlled Trial (RCT).
Urology.
2015 Sep; 86(3):482-6. doi:
10.1016/j.urology.2015.06.007. [PMID: 26135813] - Frank Giton, Nanor Sirab, Grégory Franck, Marianne Gervais, Fabien Schmidlin, Tauhid Ali, Yves Allory, Alexandre de la Taille, Francis Vacherot, Sylvain Loric, Jean Fiet. Evidence of estrone-sulfate uptake modification in young and middle-aged rat prostate.
The Journal of steroid biochemistry and molecular biology.
2015 Aug; 152(?):89-100. doi:
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Endocrinology.
2015 Jul; 156(7):2704-12. doi:
10.1210/en.2015-1130. [PMID: 25919187] - S Troll, J Gottschalk, J Heuer, A Einspanier, J Thielebein. Endocrine pregnancy monitoring in the two-toed sloth (Choloepus didactylus): 'Pregnant or not pregnant'.
Theriogenology.
2015 Jul; 84(1):137-44. doi:
10.1016/j.theriogenology.2015.02.022. [PMID: 25850609] - Alain Y Dury, Yuyong Ke, Renaud Gonthier, Maxim Isabelle, Jean-Nicolas Simard, Fernand Labrie. Validated LC-MS/MS simultaneous assay of five sex steroid/neurosteroid-related sulfates in human serum.
The Journal of steroid biochemistry and molecular biology.
2015 May; 149(?):1-10. doi:
10.1016/j.jsbmb.2015.01.006. [PMID: 25595042] - R J Santen. Vaginal administration of estradiol: effects of dose, preparation and timing on plasma estradiol levels.
Climacteric : the journal of the International Menopause Society.
2015 Apr; 18(2):121-34. doi:
10.3109/13697137.2014.947254. [PMID: 25327484] - Nilasha Banerjee, T Robert Wu, Jason Chio, Ryan Kelly, Karin A Stephenson, John Forbes, Christine Allen, John F Valliant, Reina Bendayan. (125)I-Labelled 2-Iodoestrone-3-sulfate: synthesis, characterization and OATP mediated transport studies in hormone dependent and independent breast cancer cells.
Nuclear medicine and biology.
2015 Mar; 42(3):274-82. doi:
10.1016/j.nucmedbio.2014.10.011. [PMID: 25542669] - Yohannes Hagos, Philip Hundertmark, Volodymyr Shnitsar, Venkata V V R Marada, Gerald Wulf, Gerhard Burckhardt. Renal human organic anion transporter 3 increases the susceptibility of lymphoma cells to bendamustine uptake.
American journal of physiology. Renal physiology.
2015 Feb; 308(4):F330-8. doi:
10.1152/ajprenal.00467.2014. [PMID: 25477469] - D Lee Alekel, Ulrike Genschel, Kenneth J Koehler, Heike Hofmann, Marta D Van Loan, Bonnie S Beer, Laura N Hanson, Charles T Peterson, Mindy S Kurzer. Soy Isoflavones for Reducing Bone Loss Study: effects of a 3-year trial on hormones, adverse events, and endometrial thickness in postmenopausal women.
Menopause (New York, N.Y.).
2015 Feb; 22(2):185-97. doi:
10.1097/gme.0000000000000280. [PMID: 25003624] - J L Riveros, G Schuler, B Urquieta, B Hoffmann, C Bonacic. Ovarian follicular activity during late gestation and postpartum in guanaco (Lama guanicoe).
Reproduction in domestic animals = Zuchthygiene.
2015 Feb; 50(1):129-34. doi:
10.1111/rda.12462. [PMID: 25528969] - Ting Chan, Jian Zheng, Ling Zhu, Thomas Grewal, Michael Murray, Fanfan Zhou. Putative transmembrane domain 6 of the human organic anion transporting polypeptide 1A2 (OATP1A2) influences transporter substrate binding, protein trafficking, and quality control.
Molecular pharmaceutics.
2015 Jan; 12(1):111-9. doi:
10.1021/mp500459b. [PMID: 25387129] - Marianne Hauglid Flågeng, Stian Knappskog, Jennifer Gjerde, Per Eystein Lønning, Gunnar Mellgren. Estrogens Correlate with PELP1 Expression in ER Positive Breast Cancer.
PloS one.
2015; 10(8):e0134351. doi:
10.1371/journal.pone.0134351. [PMID: 26247365] - Kei Schulz, Yohannes Hagos, Gerhard Burckhardt, Gunnar Schley, Nikolai Burzlaff, Carsten Willam, Birgitta C Burckhardt. The Isoquinolone Derived Prolyl Hydroxylase Inhibitor ICA Is a Potent Substrate of the Organic Anion Transporters 1 and 3.
Nephron.
2015; 131(4):285-9. doi:
10.1159/000442531. [PMID: 26640952] - Venkata V V R Marada, Saskia Flörl, Annett Kühne, Judith Müller, Gerhard Burckhardt, Yohannes Hagos. Interaction of human organic anion transporter 2 (OAT2) and sodium taurocholate cotransporting polypeptide (NTCP) with antineoplastic drugs.
Pharmacological research.
2015 Jan; 91(?):78-87. doi:
10.1016/j.phrs.2014.11.002. [PMID: 25481222] - Cheng-Xian Guo, Sheng Deng, Ji-Ye Yin, Zhao-Qian Liu, Wei Zhang, Hong-Hao Zhou. Schisandrin A and B induce organic anion transporting polypeptide 1B1 transporter activity.
Die Pharmazie.
2015 Jan; 70(1):29-32. doi:
. [PMID: 25975095] - Rym Chioukh, Marie-Sophie Noel-Hudson, Sandy Ribes, Natalie Fournier, Laurent Becquemont, Celine Verstuyft. Proton pump inhibitors inhibit methotrexate transport by renal basolateral organic anion transporter hOAT3.
Drug metabolism and disposition: the biological fate of chemicals.
2014 Dec; 42(12):2041-8. doi:
10.1124/dmd.114.058529. [PMID: 25239859] - Fabio Abeni, Maurizio Capelletti, Giuseppina Maria Terzano, Claudia Federici, Marisanna Speroni, Francesca Petrera, Aldo Dal Prà, Cesare Galli, Roberto Duchi, Giovanna Lazzari, Giacomo Pirlo, Riccardo Aleandri. Plasma estrone sulfate, clinical biochemistry, and milk yield of dairy cows carrying a fetus from a bull or its clone.
Theriogenology.
2014 Oct; 82(7):972-81. doi:
10.1016/j.theriogenology.2014.07.015. [PMID: 25139753] - N J Dias, K W Selcer. Steroid sulfatase mediated growth Sof human MG-63 pre-osteoblastic cells.
Steroids.
2014 Oct; 88(?):77-82. doi:
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The Journal of clinical endocrinology and metabolism.
2014 Oct; 99(10):3728-36. doi:
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Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
2014 Oct; 32(28):3111-7. doi:
10.1200/jco.2014.56.1068. [PMID: 25135988] - Hui Zhang, Jianghong Shi, Xiaowei Liu, Xinmin Zhan, Qingcai Chen. Occurrence and removal of free estrogens, conjugated estrogens, and bisphenol A in manure treatment facilities in East China.
Water research.
2014 Jul; 58(?):248-57. doi:
10.1016/j.watres.2014.03.074. [PMID: 24768704] - Bhagu R Bhavnani, Frank Z Stanczyk. Pharmacology of conjugated equine estrogens: efficacy, safety and mechanism of action.
The Journal of steroid biochemistry and molecular biology.
2014 Jul; 142(?):16-29. doi:
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Trials.
2014 May; 15(?):198. doi:
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European journal of cancer (Oxford, England : 1990).
2014 Apr; 50(6):1055-64. doi:
10.1016/j.ejca.2014.01.007. [PMID: 24507547] - Shanshan Zhao, Rowan T Chlebowski, Garnet L Anderson, Lewis H Kuller, JoAnn E Manson, Margery Gass, Ruth Patterson, Thomas E Rohan, Dorothy S Lane, Shirley Aa Beresford, Sayeh Lavasani, Jacques E Rossouw, Ross L Prentice. Sex hormone associations with breast cancer risk and the mediation of randomized trial postmenopausal hormone therapy effects.
Breast cancer research : BCR.
2014 Mar; 16(2):R30. doi:
10.1186/bcr3632. [PMID: 24670297] - V Sini, G Lunardi, M Cirillo, M Turazza, C Bighin, S Giraudi, A Levaggi, P Piccioli, G Bisagni, R Gnoni, G Stridi, M Porpiglia, E Picardo, R Ponzone, D Marenco, M Mansutti, F Puglisi, L Del Mastro. Body mass index and circulating oestrone sulphate in women treated with adjuvant letrozole.
British journal of cancer.
2014 Mar; 110(5):1133-8. doi:
10.1038/bjc.2014.2. [PMID: 24448359] - Arjinajarn Phatchawan, Srimaroeng Chutima, Chatsudthipong Varanuj, Lungkaphin Anusorn. Decreased renal organic anion transporter 3 expression in type 1 diabetic rats.
The American journal of the medical sciences.
2014 Mar; 347(3):221-7. doi:
10.1097/maj.0b013e3182831740. [PMID: 23470271] - Angelica Crisci, Alessandra Rota, Duccio Panzani, Micaela Sgorbini, Jennifer C Ousey, Francesco Camillo. Clinical, ultrasonographic, and endocrinological studies on donkey pregnancy.
Theriogenology.
2014 Jan; 81(2):275-83. doi:
10.1016/j.theriogenology.2013.09.026. [PMID: 24157228] - Nicholas L Smith, Marc Blondon, Kerri L Wiggins, Laura B Harrington, Astrid van Hylckama Vlieg, James S Floyd, Melody Hwang, Joshua C Bis, Barbara McKnight, Kenneth M Rice, Thomas Lumley, Frits R Rosendaal, Susan R Heckbert, Bruce M Psaty. Lower risk of cardiovascular events in postmenopausal women taking oral estradiol compared with oral conjugated equine estrogens.
JAMA internal medicine.
2014 Jan; 174(1):25-31. doi:
10.1001/jamainternmed.2013.11074. [PMID: 24081194] - Naoki Isobe, Chihiro Iwamoto, Hirokazu Kubota, Yukinori Yoshimura. Relationship between the somatic cell count in milk and reproductive function in peripartum dairy cows.
The Journal of reproduction and development.
2014; 60(6):433-7. doi:
10.1262/jrd.2014-065. [PMID: 25196356] - Thomas B Clarkson, Kelly F Ethun, Nicholas M Pajewski, Debbie Golden, Edison Floyd, Susan E Appt. Effects of bazedoxifene, conjugated equine estrogens, and a tissue-selective estrogen complex containing both bazedoxifene and conjugated equine estrogens on cerebral artery atherosclerosis in postmenopausal monkeys.
Menopause (New York, N.Y.).
2014 Jan; 21(1):8-14. doi:
10.1097/gme.0b013e31829370e5. [PMID: 23676638] - Hui Zhang, Jianghong Shi, Xiaowei Liu, Xinmin Zhan, Jinhua Dang, Ting Bo. Occurrence of free estrogens, conjugated estrogens, and bisphenol A in fresh livestock excreta and their removal by composting in North China.
Environmental science and pollution research international.
2014; 21(16):9939-47. doi:
10.1007/s11356-014-3002-9. [PMID: 24828825] - Hui Gao, Shui Xi, Ling Xu. [Effects of raloxifene combined with conjugated equine estrogen on prothrombotic state in ovariectomized rats].
Zhonghua fu chan ke za zhi.
2013 Dec; 48(12):935-8. doi:
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Menopause (New York, N.Y.).
2013 Nov; 20(11):1126-32. doi:
10.1097/gme.0b013e31828ac8cc. [PMID: 23632659] - B Williamson, A C Soars, A Owen, P White, R J Riley, M G Soars. Dissecting the relative contribution of OATP1B1-mediated uptake of xenobiotics into human hepatocytes using siRNA.
Xenobiotica; the fate of foreign compounds in biological systems.
2013 Oct; 43(10):920-31. doi:
10.3109/00498254.2013.776194. [PMID: 23461378] - Yoshihisa Shitara, Kumiko Takeuchi, Toshiharu Horie. Long-lasting inhibitory effects of saquinavir and ritonavir on OATP1B1-mediated uptake.
Journal of pharmaceutical sciences.
2013 Sep; 102(9):3427-35. doi:
10.1002/jps.23477. [PMID: 23440887] - L Torres-Santiago, V Mericq, M Taboada, N Unanue, K O Klein, R Singh, J Hossain, R J Santen, J L Ross, N Mauras. Metabolic effects of oral versus transdermal 17β-estradiol (E₂): a randomized clinical trial in girls with Turner syndrome.
The Journal of clinical endocrinology and metabolism.
2013 Jul; 98(7):2716-24. doi:
10.1210/jc.2012-4243. [PMID: 23678038] - Avijit Haldar, Saumen K Pal, Sandip Chakraborty, Mausumi Hazorika, Subhransu Pan, Debasis Majumdar, Chanchal K Biswas, Aditi Patra, Rouhollah Mirmahmoudi, Bukkaaraya S Prakash. Endocrine markers for identifying prolificacy potential and predicting fetal number in goats.
Animal reproduction science.
2013 Jul; 140(1-2):54-61. doi:
10.1016/j.anireprosci.2013.05.005. [PMID: 23787106] - Luciana Barbosa Firmes, Najara Oliveira Belo, Adelina Martha Reis. Conjugated equine estrogens and estradiol benzoate differentially modulate the natriuretic peptide system in spontaneously hypertensive rats.
Menopause (New York, N.Y.).
2013 May; 20(5):554-60. doi:
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