Quinagolide hydrochloride (BioDeep_00000694206)
代谢物信息卡片
Quinagolide (hydrochloride)
化学式: C20H34ClN3O3S (431.20092840000007)
中文名称: 盐酸喹高莱
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCN1CC(CC2C1CC3=C(C2)C(=CC=C3)O)NS(=O)(=O)N(CC)CC.Cl
InChI: /m1./s1
描述信息
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents > D018491 - Dopamine Agonists
Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer[1][2].
Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective and orally active dopamine D2 receptor agonist. Quinagolide hydrochloride is an inhibitor of prolactin. Quinagolide hydrochloride down-regulates AKT levels and its phosphorylation. Quinagolide hydrochloride shows antitumor effects, it can be used for the research of cancer[1][2].
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文献列表
- N Vanacker, S Ollier, F Beaudoin, R Blouin, P Lacasse. Effect of inhibiting the lactogenic signal at calving on milk production and metabolic and immune perturbations in dairy cows.
Journal of dairy science.
2017 Jul; 100(7):5782-5791. doi:
10.3168/jds.2017-12570. [PMID: 28501406] - S Ollier, F Beaudoin, N Vanacker, P Lacasse. Effect of reducing milk production using a prolactin-release inhibitor or a glucocorticoid on metabolism and immune functions in cows subjected to acute nutritional stress.
Journal of dairy science.
2016 Dec; 99(12):9949-9961. doi:
10.3168/jds.2016-11711. [PMID: 27743662] - S Ollier, X Zhao, P Lacasse. Effects of feed restriction and prolactin-release inhibition at drying off on metabolism and mammary gland involution in cows.
Journal of dairy science.
2014; 97(8):4942-54. doi:
10.3168/jds.2014-7914. [PMID: 24881791] - S Ollier, X Zhao, P Lacasse. Effect of prolactin-release inhibition on milk production and mammary gland involution at drying-off in cows.
Journal of dairy science.
2013 Jan; 96(1):335-43. doi:
10.3168/jds.2012-5955. [PMID: 23164222] - Peter Cackett, Graeme Eunson, Louise Bath, Alan Mulvihill. Proptosis as the presenting sign of giant prolactinoma in a prepubertal boy: successful resolution of hydrocephalus by use of medical therapy.
Future oncology (London, England).
2012 Dec; 8(12):1621-6. doi:
10.2217/fon.12.149. [PMID: 23231524] - Rosalie Broekhof, Manon J Gosselink, Hanno Pijl, Erik J Giltay. The effect of aripiprazole and quinagolide, a dopamine agonist, in a patient with symptomatic pituitary prolactinoma and chronic psychosis.
General hospital psychiatry.
2012 Mar; 34(2):209.e1-3. doi:
10.1016/j.genhosppsych.2011.07.004. [PMID: 21872335] - Robert Krysiak, Agnieszka Kędzia, Bogusław Okopień. Unfavorable effects of hyperprolactinemia in autoimmune endocrine disorders.
Neuro endocrinology letters.
2012; 33(3):298-300. doi:
NULL. [PMID: 22635088] - P Lacasse, V Lollivier, R M Bruckmaier, Y R Boisclair, G F Wagner, M Boutinaud. Effect of the prolactin-release inhibitor quinagolide on lactating dairy cows.
Journal of dairy science.
2011 Mar; 94(3):1302-9. doi:
10.3168/jds.2010-3649. [PMID: 21338795] - Gergely Lakatos, Nikolette Szücs, Zoltán Kender, Sándor Czirják, Károly Rácz. [Macroprolactinemia associated with pituitary macroadenoma: treatment with quinagolide].
Orvosi hetilap.
2010 Jun; 151(26):1072-5. doi:
10.1556/oh.2010.28896. [PMID: 20558354] - M Sarkar, B K Dutta Borah, B S Prakash. Efficacy of Ovsynch protocol with antiprolactin treatment for timed artificial insemination during non-breeding seasons in yaks (Poephagus grunniens L.).
Reproduction in domestic animals = Zuchthygiene.
2010 Jun; 45(3):393-8. doi:
10.1111/j.1439-0531.2008.01196.x. [PMID: 19735436] - K S Roy, B S Prakash. Plasma progesterone, oestradiol-17β and total oestrogen profiles in relation to oestrous behaviour during induced ovulation in Murrah buffalo heifers.
Journal of animal physiology and animal nutrition.
2009 Aug; 93(4):486-95. doi:
10.1111/j.1439-0396.2008.00830.x. [PMID: 18507697] - K S Roy, B S Prakash. Changes in endocrine profiles during ovsynch and ovsynch plus norprolac treatment in Murrah buffalo heifers at hot summer season.
Tropical animal health and production.
2009 Apr; 41(4):677-87. doi:
10.1007/s11250-008-9241-3. [PMID: 18932011] - Antoni Hrycek, Grazyna Pochopień-Kenig, Joanna Scieszka. Selected acute phase proteins and interleukin-6 in systemic lupus erythematosus patients treated with low doses of quinagolide.
Autoimmunity.
2007 May; 40(3):217-22. doi:
10.1080/08916930701306817. [PMID: 17453721] - K S Roy, B S Prakash. Development and validation of a simple, sensitive enzyme immunoassay (EIA) for quantification of prolactin in buffalo plasma.
Theriogenology.
2007 Feb; 67(3):572-9. doi:
10.1016/j.theriogenology.2006.08.018. [PMID: 17049591] - Anne Barlier, Philippe Jaquet. Quinagolide--a valuable treatment option for hyperprolactinaemia.
European journal of endocrinology.
2006 Feb; 154(2):187-95. doi:
10.1530/eje.1.02075. [PMID: 16452531] - Miklós Góth, Erika Hubina, László Kovács, István Szabolcs. [Novel pharmacologic therapies in acromegaly].
Orvosi hetilap.
2002 May; 143(19 Suppl):1057-62. doi:
NULL. [PMID: 12063860] - A Saveanu, I Morange-Ramos, G Gunz, H Dufour, A Enjalbert, P Jaquet. A luteinizing hormone-, alpha-subunit- and prolactin-secreting pituitary adenoma responsive to somatostatin analogs: in vivo and in vitro studies.
European journal of endocrinology.
2001 Jul; 145(1):35-41. doi:
10.1530/eje.0.1450035. [PMID: 11415850] - A Hrycek, P Cieślik, J Tustanowski, S Nowak, P Jedynak. Selected serum cytokines in systemic lupus erythematosus treated with quinagolide.
Lupus.
2001; 10(6):424-30. doi:
10.1191/096120301678646173. [PMID: 11434578] - P N Schultz, L Ginsberg, I E McCutcheon, N Samaan, M Leavens, R F Gagel. Quinagolide in the management of prolactinoma.
Pituitary.
2000 Dec; 3(4):239-49. doi:
10.1023/a:1012884214668. [PMID: 11788012] - V Rohmer, E Freneau, I Morange, C Simonetta. Efficacy of quinagolide in resistance to dopamine agonists: results of a multicenter study. Club de l'Hypophyse.
Annales d'endocrinologie.
2000 Nov; 61(5):411-7. doi:
NULL. [PMID: 11084391] - F R Nobels, W W de Herder, W M van den Brink, D J Kwekkeboom, L J Hofland, J Zuyderwijk, F H de Jong, S W Lamberts. Long-term treatment with the dopamine agonist quinagolide of patients with clinically non-functioning pituitary adenoma.
European journal of endocrinology.
2000 Nov; 143(5):615-21. doi:
10.1530/eje.0.1430615. [PMID: 11078985] - S Koloszár, A Keresztúri, L Kovács. [Treatment of hyperprolactinemic anovulation with the dopamin-agonist quinagolide].
Orvosi hetilap.
2000 Jul; 141(29):1621-3. doi:
NULL. [PMID: 10962898] - D A De Luis, A Becerra, M Lahera, J I Botella, Valero, C Varela. A randomized cross-over study comparing cabergoline and quinagolide in the treatment of hyperprolactinemic patients.
Journal of endocrinological investigation.
2000 Jul; 23(7):428-34. doi:
10.1007/bf03343751. [PMID: 11005266] - A Di Sarno, M L Landi, P Marzullo, C Di Somma, R Pivonello, G Cerbone, G Lombardi, A Colao. The effect of quinagolide and cabergoline, two selective dopamine receptor type 2 agonists, in the treatment of prolactinomas.
Clinical endocrinology.
2000 Jul; 53(1):53-60. doi:
10.1046/j.1365-2265.2000.01016.x. [PMID: 10931080] - A Colao, C Di Somma, S Loche, A Di Sarno, M Klain, R Pivonello, M Pietrosante, M Salvatore, G Lombardi. Prolactinomas in adolescents: persistent bone loss after 2 years of prolactin normalization.
Clinical endocrinology.
2000 Mar; 52(3):319-27. doi:
10.1046/j.1365-2265.2000.00902.x. [PMID: 10718830] - J Webster. Dopamine agonist therapy in hyperprolactinemia.
The Journal of reproductive medicine.
1999 Dec; 44(12 Suppl):1105-10. doi:
NULL. [PMID: 10649819] - P Marzullo, D Ferone, C Di Somma, R Pivonello, M Filippella, G Lombardi, A Colao. Efficacy of combined treatment with lanreotide and cabergoline in selected therapy-resistant acromegalic patients.
Pituitary.
1999; 1(2):115-20. doi:
10.1023/a:1009932521242. [PMID: 11081189] - L Ioannidou-Mouzaka, M Niagassas, A Galanos, A Kalovidouris. Pilot study on the treatment of cyclical mastodynia with Quinagolide.
European journal of gynaecological oncology.
1999; 20(2):117-21. doi:
NULL. [PMID: 10376428] - A Colao, S Loche, M Cappa, A Di Sarno, M L Landi, F Sarnacchiaro, G Facciolli, G Lombardi. Prolactinomas in children and adolescents. Clinical presentation and long-term follow-up.
The Journal of clinical endocrinology and metabolism.
1998 Aug; 83(8):2777-80. doi:
10.1210/jcem.83.8.5001. [PMID: 9709946] - C Di Somma, A Colao, A Di Sarno, M Klain, M L Landi, G Facciolli, R Pivonello, N Panza, M Salvatore, G Lombardi. Bone marker and bone density responses to dopamine agonist therapy in hyperprolactinemic males.
The Journal of clinical endocrinology and metabolism.
1998 Mar; 83(3):807-13. doi:
10.1210/jcem.83.3.4674. [PMID: 9506732] - M Bontenbal, J A Foekens, S W Lamberts, F H de Jong, W L van Putten, H J Braun, J T Burghouts, G H van der Linden, J G Klijn. Feasibility, endocrine and anti-tumour effects of a triple endocrine therapy with tamoxifen, a somatostatin analogue and an antiprolactin in post-menopausal metastatic breast cancer: a randomized study with long-term follow-up.
British journal of cancer.
1998; 77(1):115-22. doi:
10.1038/bjc.1998.18. [PMID: 9459155] - E Delgrange, J Crabbé, J Donckier. Late development of resistance to bromocriptine in a patient with macroprolactinoma.
Hormone research.
1998; 49(5):250-3. doi:
10.1159/000023180. [PMID: 9568811] - D Ferone, S Lastoria, A Colao, P Varrella, G Cerbone, W Acampa, B Merola, M Salvatore, G Lombardi. Correlation of scintigraphic results using 123I-methoxybenzamide with hormone levels and tumor size response to quinagolide in patients with pituitary adenomas.
The Journal of clinical endocrinology and metabolism.
1998 Jan; 83(1):248-52. doi:
10.1210/jcem.83.1.4493. [PMID: 9435450] - A Colao, D Ferone, P Marzullo, A Di Sarno, G Cerbone, F Sarnacchiaro, S Cirillo, B Merola, G Lombardi. Effect of different dopaminergic agents in the treatment of acromegaly.
The Journal of clinical endocrinology and metabolism.
1997 Feb; 82(2):518-23. doi:
10.1210/jcem.82.2.3648. [PMID: 9024247] - A Tabarin, B Catargi. [Treatment of macroprolactinomas with quinagolide (Norprolac)].
Annales d'endocrinologie.
1997; 58(2):87-94. doi:
NULL. [PMID: 9239226] - W W de Herder, A E Reijs, D J Kwekkeboom, L J Hofland, F R Nobels, H Y Oei, E P Krenning, S W Lamberts. In vivo imaging of pituitary tumours using a radiolabelled dopamine D2 receptor radioligand.
Clinical endocrinology.
1996 Dec; 45(6):755-67. doi:
10.1046/j.1365-2265.1996.8650876.x. [PMID: 9039343] - A Colao, M De Rosa, F Sarnacchiaro, A Di Sarno, M L Landi, E Iervolino, S Zarrilli, B Merola, G Lombardi. Chronic treatment with CV 205-502 restores the gonadal function in hyperprolactinemic males.
European journal of endocrinology.
1996 Nov; 135(5):548-52. doi:
10.1530/eje.0.1350548. [PMID: 8980156] - I Morange, A Barlier, I Pellegrini, T Brue, A Enjalbert, P Jaquet. Prolactinomas resistant to bromocriptine: long-term efficacy of quinagolide and outcome of pregnancy.
European journal of endocrinology.
1996 Oct; 135(4):413-20. doi:
10.1530/eje.0.1350413. [PMID: 8921822] - C W Bodmer, S L Atkin, M W Savage, E A Masson, M C White. Effects of quinagolide (CV 205-502), a selective D2-agonist, on vascular reactivity in patients with a prolactin-secreting adenoma.
Clinical endocrinology.
1995 Jul; 43(1):49-53. doi:
10.1111/j.1365-2265.1995.tb01893.x. [PMID: 7641411] - A Colao, B Merola, F Sarnacchiaro, A Di Sarno, M L Landi, P Marzullo, G Cerbone, D Ferone, G Lombardi. Comparison among different dopamine-agonists of new formulation in the clinical management of macroprolactinomas.
Hormone research.
1995; 44(5):222-8. doi:
10.1159/000184630. [PMID: 8582715] - J A Kremer, L A Schellekens, M F Segers, C M Thomas, R Rolland. Circulating inhibin levels in lactating and nonlactating women.
Fertility and sterility.
1994 Dec; 62(6):1150-6. doi:
10.1016/s0015-0282(16)57177-5. [PMID: 7957977] - B Merola, F Sarnacchiaro, A Colao, C Di Somma, A Di Sarno, D Ferone, A Selleri, M L Landi, G Schettini, C Nappi. Positive response to compound CV 205-502 in hyperprolactinemic patients resistant to or intolerant of bromocriptine.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
1994 Sep; 8(3):175-81. doi:
10.3109/09513599409072452. [PMID: 7847102] - L Lévy, V Alvaro, C Dubray, D Joubert. Ca(2+)-dependent protein kinase C isoforms in rat pituitary hyperplasia: effect of in vivo treatment with quinagolide.
European journal of pharmacology.
1994 Aug; 268(3):327-34. doi:
10.1016/0922-4106(94)90057-4. [PMID: 7528679] - B Glaser, Y Nesher, S Barziliai. Long-term treatment of bromocriptine-intolerant prolactinoma patients with CV 205-502.
The Journal of reproductive medicine.
1994 Jun; 39(6):449-54. doi:
NULL. [PMID: 7932398] - T Svoboda, H Kotzmann, M Clodi, P Bernecker, G Geyer, A Luger. The non ergot D2-dopamine agonist CV 205-502 decreases growth hormone concentrations in acromegalic patients.
Endocrine research.
1994 Feb; 20(1):59-63. doi:
10.1080/07435809409035856. [PMID: 7909510] - J Trouillas, P Chevallier, B Claustrat, E Hooghe-Peters, C Dubray, B Rousset, C Girod. Inhibitory effects of the dopamine agonists quinagolide (CV 205-502) and bromocriptine on prolactin secretion and growth of SMtTW pituitary tumors in the rat.
Endocrinology.
1994 Jan; 134(1):401-10. doi:
10.1210/endo.134.1.7903933. [PMID: 7903933] - B Merola, F Sarnacchiaro, A Colao, C Di Somma, A Di Sarno, M L Landi, P Marzullo, N Panza, C Battista, G Lombardi. CV 205-502 in the treatment of tumoral and non-tumoral hyperprolactinemic states.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
1994; 48(3-4):167-74. doi:
10.1016/0753-3322(94)90105-8. [PMID: 7993981] - T Nickelsen, E Jungmann, P Althoff, P M Schumm-Draeger, K H Usadel. Treatment of macroprolactinoma with the new potent non-ergot D2-dopamine agonist quinagolide and effects on prolactin levels, pituitary function, an the renin-aldosterone system. Results of a clinical long-term study.
Arzneimittel-Forschung.
1993 Apr; 43(4):421-5. doi:
NULL. [PMID: 8098604] - Y Tomita, R W Engelman, I Bauer-Sardina, N K Day, R A Good. Improved enzyme immunosorbent assay for mouse prolactin using penicillinase as label.
Journal of immunological methods.
1992 Jul; 151(1-2):269-75. doi:
10.1016/0022-1759(92)90127-f. [PMID: 1352793] - W J Fassbender, H Stracke, G Bachmann, W Rau, K Federlin. Disappearance of a pituitary tumor after 15 months of treatment with CV 205-502, a new dopamine agonist.
The Clinical investigator.
1992 May; 70(5):444-6. doi:
10.1007/bf00235530. [PMID: 1350936] - T Brue, I Pellegrini, G Gunz, I Morange, D Dewailly, J Brownell, A Enjalbert, P Jaquet. Effects of the dopamine agonist CV 205-502 in human prolactinomas resistant to bromocriptine.
The Journal of clinical endocrinology and metabolism.
1992 Mar; 74(3):577-84. doi:
10.1210/jcem.74.3.1346788. [PMID: 1346788] - D J Kwekkeboom, S W Lamberts. Long-term treatment with the dopamine agonist CV 205-502 of patients with a clinically non-functioning, gonadotroph, or alpha-subunit secreting pituitary adenoma.
Clinical endocrinology.
1992 Feb; 36(2):171-6. doi:
10.1111/j.1365-2265.1992.tb00953.x. [PMID: 1348979] - T Brue, I Pellegrini, A Priou, I Morange, P Jaquet. Prolactinomas and resistance to dopamine agonists.
Hormone research.
1992; 38(1-2):84-9. doi:
10.1159/000182496. [PMID: 1306523] - P S Barnett, E Palazidou, J P Miell, P B Coskeran, J Butler, J M Dawson, J Maccabe, A M McGregor. Endocrine function, psychiatric and clinical consequences in patients with macroprolactinomas after long-term treatment with the new non-ergot dopamine agonist CV205-502.
The Quarterly journal of medicine.
1991 Nov; 81(295):891-906. doi:
NULL. [PMID: 1687293] - T Svoboda, A Luger, E Knosp, G Geyer. [Treatment of prolactinoma with a new dopamine agonist].
Deutsche medizinische Wochenschrift (1946).
1991 Aug; 116(33):1224-7. doi:
10.1055/s-2008-1063739. [PMID: 1678695] - C Rasmussen, J Brownell, T Bergh. Clinical response and prolactin concentration in hyperprolactinemic women during and after treatment for 24 months with the new dopamine agonist, CV 205-502.
Acta endocrinologica.
1991 Aug; 125(2):170-6. doi:
10.1530/acta.0.1250170. [PMID: 1680264] - P F van der Heijden, W de Wit, J Brownell, J Schoemaker, R Rolland. CV 205-502, a new dopamine agonist, versus bromocriptine in the treatment of hyperprolactinaemia.
European journal of obstetrics, gynecology, and reproductive biology.
1991 Jul; 40(2):111-8. doi:
10.1016/0028-2243(91)90101-p. [PMID: 1676973] - A J van der Lely, J Brownell, S W Lamberts. The efficacy and tolerability of CV 205-502 (a nonergot dopaminergic drug) in macroprolactinoma patients and in prolactinoma patients intolerant to bromocriptine.
The Journal of clinical endocrinology and metabolism.
1991 May; 72(5):1136-41. doi:
10.1210/jcem-72-5-1136. [PMID: 1673685] - J P Miell, R Corder, F P Pralong, R C Gaillard. Effects of dexamethasone on growth hormone (GH)-releasing hormone, arginine- and dopaminergic stimulated GH secretion, and total plasma insulin-like growth factor-I concentrations in normal male volunteers.
The Journal of clinical endocrinology and metabolism.
1991 Mar; 72(3):675-81. doi:
10.1210/jcem-72-3-675. [PMID: 1671785] - L Duranteau, P Chanson, A Lavoinne, S Horlait, J Lubetzki, J M Kuhn. Effect of the new dopaminergic agonist CV 205-502 on plasma prolactin levels and tumour size in bromocriptine-resistant prolactinomas.
Clinical endocrinology.
1991 Jan; 34(1):25-9. doi:
10.1111/j.1365-2265.1991.tb01731.x. [PMID: 1672268] - P Birman, F Bai-Grenier, D Joubert. [EGF binding site number of rat anterior pituitary is increased by chronic administration with dopaminergic agonist, CV 205-502].
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie.
1991; 312(6):241-5. doi:
NULL. [PMID: 1675150] - J W van't Verlaat, R J Croughs, J Brownell. Treatment of macroprolactinomas with a new non-ergot, long-acting dopaminergic drug, CV 205-502.
Clinical endocrinology.
1990 Nov; 33(5):619-24. doi:
10.1111/j.1365-2265.1990.tb03900.x. [PMID: 1979262] - O Serri, H Beauregard, J Lesage, L Pedneault, R Comtois, N Jilwan, M Somma, L Vachon, J Brownell. Long term treatment with CV 205-502 in patients with prolactin-secreting pituitary macroadenomas.
The Journal of clinical endocrinology and metabolism.
1990 Sep; 71(3):682-7. doi:
10.1210/jcem-71-3-682. [PMID: 2394774] - P S Barnett, J M Dawson, J Butler, P B Coskeran, J J Maccabe, A M McGregor. CV205-502, a new non-ergot dopamine agonist, reduces prolactinoma size in man.
Clinical endocrinology.
1990 Aug; 33(2):307-16. doi:
10.1111/j.1365-2265.1990.tb00495.x. [PMID: 1977537] - Y Khalfallah, B Claustrat, M Grochowicki, F Flocard, S Horlait, P Serusclat, G Sassolas. Effects of a new prolactin inhibitor, CV 205-502, in the treatment of human macroprolactinomas.
The Journal of clinical endocrinology and metabolism.
1990 Aug; 71(2):354-9. doi:
10.1210/jcem-71-2-354. [PMID: 1974262] - M L Vance, M Lipper, A Klibanski, B M Biller, N A Samaan, M E Molitch. Treatment of prolactin-secreting pituitary macroadenomas with the long-acting non-ergot dopamine agonist CV 205-502.
Annals of internal medicine.
1990 May; 112(9):668-73. doi:
10.7326/0003-4819-112-9-668. [PMID: 1970714] - P Hedner, S Valdemarsson. Reduced size of a hormonally silent pituitary adenoma during treatment with CV 205-502, a new dopamine agonist mainly stimulating D2 receptors.
Neurosurgery.
1989 Dec; 25(6):948-50. doi:
10.1097/00006123-198912000-00015. [PMID: 2532309] - P Birman, P Touraine, F Bai-Grenier, C Dubray, T Kaabache, F Peillon, D Joubert. The stimulated C-kinase activity in estradiol-treated rat pituitaries is reduced by chronic treatment with the dopamine agonist CV 205-502.
Acta endocrinologica.
1989 Oct; 121(4):489-94. doi:
10.1530/acta.0.1210489. [PMID: 2572127] - P F van der Heijden, R E Lappöhn, R S Corbey, W B de Goeij, J Brownell, R Rolland. The effectiveness, safety, and tolerability of CV 205-502 in hyperprolactinemic women: a 12-month study.
Fertility and sterility.
1989 Oct; 52(4):574-9. doi:
10.1016/s0015-0282(16)60966-4. [PMID: 2806597] - C B Newman, A M Hurley, D L Kleinberg. Effect of CV 205-502 in hyperprolactinaemic patients intolerant of bromocriptine.
Clinical endocrinology.
1989 Oct; 31(4):391-400. doi:
10.1111/j.1365-2265.1989.tb01263.x. [PMID: 2576397] - R C Gaillard, K Abeywickrama, J Brownell, A F Muller. Specific effect of CV 205-502, a potent nonergot dopamine agonist, during a combined anterior pituitary function test.
The Journal of clinical endocrinology and metabolism.
1989 Feb; 68(2):329-35. doi:
10.1210/jcem-68-2-329. [PMID: 2563733] - M L Vance, J R Cragun, C Reimnitz, R J Chang, E Rashef, R E Blackwell, M M Miller, M E Molitch. CV 205-502 treatment of hyperprolactinemia.
The Journal of clinical endocrinology and metabolism.
1989 Feb; 68(2):336-9. doi:
10.1210/jcem-68-2-336. [PMID: 2521863] - P F van der Heijden, R Rolland, C M Thomas, J Brownell. Endocrine effects of CV 205-502, a new dopamine agonist, in hyperprolactinemic women.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology.
1988 Sep; 2(3):233-48. doi:
10.3109/09513599809029348. [PMID: 3067546] - R C Gaillard, J Brownell. Hormonal effects of CV 205-502, a novel octahydrobenzo [g] quinoline with potent dopamine agonist properties.
Life sciences.
1988; 43(17):1355-62. doi:
10.1016/0024-3205(88)90301-3. [PMID: 2903425] - C Rasmussen, T Bergh, L Wide, J Brownell. CV 205-502: a new long-acting drug for inhibition of prolactin hypersecretion.
Clinical endocrinology.
1987 Mar; 26(3):321-6. doi:
10.1111/j.1365-2265.1987.tb00789.x. [PMID: 3308186]