TIARAMIDE HYDROCHLORIDE (BioDeep_00000694203)
代谢物信息卡片
化学式: C15H19Cl2N3O3S (391.0524124000001)
中文名称: 噻拉米特盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CN(CCN1CCO)C(=O)CN2C3=C(C=CC(=C3)Cl)SC2=O.Cl
InChI: 1H
描述信息
D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
C78273 - Agent Affecting Respiratory System > C29712 - Anti-asthmatic Agent > C319 - Bronchodilator
D018373 - Peripheral Nervous System Agents > D018689 - Sensory System Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D002491 - Central Nervous System Agents > D000700 - Analgesics
D000893 - Anti-Inflammatory Agents
D018501 - Antirheumatic Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- M Nakamura, A Ohishi, N Aosaki, K Hamaguchi. Norfloxacin-induced acute interstitial nephritis.
Nephron.
2000 Oct; 86(2):204-5. doi:
10.1159/000045749. [PMID: 11015000] - A Takeda, T Shinohara. Simultaneous analysis of tiaramide metabolites in horse urine and plasma by solid-phase extraction and reversed-phase ion-pair liquid chromatography.
Journal of analytical toxicology.
1995 Oct; 19(6):435-42. doi:
10.1093/jat/19.6.435. [PMID: 8926738] - K Iwasaki, Y Tokuma, K Noda, H Noguchi. Age- and sex-related changes of sulfotransferase activities in the rat.
Chemico-biological interactions.
1994 Jun; 92(1-3):209-17. doi:
10.1016/0009-2797(94)90064-7. [PMID: 8033254] - Y Harima, T Maekawa, Y Miyauchi, T Tsutsui, T Sakabe, A Koshiro. Intoxication with sulindac, tiaramide hydrochloride and diclofenac sodium.
Intensive care medicine.
1987; 13(5):361-2. doi:
10.1007/bf00255796. [PMID: 3655104] - Y Suzuki, M Ito, N Saito, T Nagamatsu. [Antinephritic effect of tiaramide on experimental nephritis in rats. (1). Effects on nephrotic-type and crescentic-type anti-GBM nephritis].
Nihon Jinzo Gakkai shi.
1984 Feb; 26(2):251-61. doi:
NULL. [PMID: 6748338] - K Iwasaki, T Shiraga, K Noda, K Tada, H Noguchi. Metabolism of tiaramide in vitro. III. Sulphoconjugation of alicyclic amine and alcoholic hydroxyl group by hepatic 105 000 g supernatants.
Xenobiotica; the fate of foreign compounds in biological systems.
1983 Sep; 13(9):565-74. doi:
10.3109/00498258309052296. [PMID: 6659551] - K Iwasaki, T Shiraga, K Noda, K Tada, H Noguchi. Terminal N-sulphoconjugation of an alicyclic amine (piperazine), identified as a new metabolite of tiaramide in mouse and rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1983 May; 13(5):273-8. doi:
10.3109/00498258309052264. [PMID: 6636823] - H H Li, W P Feeney. Semi-automated gas chromatographic method for the assay of tiaramide (RHC 2592) in serum samples.
Journal of chromatography.
1982 Oct; 232(1):79-84. doi:
10.1016/s0378-4347(00)86009-0. [PMID: 7142340] - H Noguchi, K Iwasaki. Metabolism of tiaramide in vitro. II. Oxidation of piperazineethanol group in tiaramide by 105 000 g supernatants from monkey and rat liver.
Xenobiotica; the fate of foreign compounds in biological systems.
1982 Aug; 12(8):499-508. doi:
10.3109/00498258209038928. [PMID: 6755927] - L J Klunk, P S Riska, D E Maynard. The disposition and metabolism of 14C-tiaramide . HCl in man.
Drug metabolism and disposition: the biological fate of chemicals.
1982 May; 10(3):241-5. doi:
NULL. [PMID: 6125356] - H Noguchi, K Tada, K Iwasaki. Urinary metabolite profile of tiaramide in man and in some animal species.
Xenobiotica; the fate of foreign compounds in biological systems.
1982 Apr; 12(4):211-20. doi:
10.3109/00498258209052458. [PMID: 7113257] - K Iwasaki, H Noguchi, T Kamataki, R Kato. Metabolism of tiaramide in vitro. I. Oxidative metabolism of tiaramide by human and rat liver microsomes.
Xenobiotica; the fate of foreign compounds in biological systems.
1982 Apr; 12(4):221-6. doi:
10.3109/00498258209052459. [PMID: 7113258] - H Noguchi, M Okui, K Noda, R Kato. Disposition and metabolic fate of tiaramide hydrochloride, a new anti-inflammatory agent, in the rat.
Xenobiotica; the fate of foreign compounds in biological systems.
1977 Aug; 7(8):491-503. doi:
10.3109/00498257709035808. [PMID: 888450]