metomidate (BioDeep_00000694184)

   


代谢物信息卡片


metomidate

化学式: C13H14N2O2 (230.1055)
中文名称: 美托咪酯
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C1=CC=CC=C1)N2C=NC=C2C(=O)OC
InChI: InChI=1S/C13H14N2O2/c1-10(11-6-4-3-5-7-11)15-9-14-8-12(15)13(16)17-2/h3-10H,1-2H3

描述信息

D002491 - Central Nervous System Agents > D002492 - Central Nervous System Depressants > D006993 - Hypnotics and Sedatives
C78272 - Agent Affecting Nervous System > C29756 - Sedative and Hypnotic

同义名列表

2 个代谢物同义名

metomidate; Metomidate



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Salvatore Bongarzone, Filippo Basagni, Teresa Sementa, Nisha Singh, Caleb Gakpetor, Vincent Faugeras, Jayanta Bordoloi, Antony D Gee. Development of [18F]FAMTO: A novel fluorine-18 labelled positron emission tomography (PET) radiotracer for imaging CYP11B1 and CYP11B2 enzymes in adrenal glands. Nuclear medicine and biology. 2019 Jan; 68-69(?):14-21. doi: 10.1016/j.nucmedbio.2018.11.002. [PMID: 30578137]
  • Rachel J Chance, Gary A Cameron, Mark Fordyce, Patricia Noguera, Tiehui Wang, Catherine Collins, Christopher J Secombes, Bertrand Collet. Effects of repeated anaesthesia on gill and general health of Atlantic salmon, Salmo salar. Journal of fish biology. 2018 Dec; 93(6):1069-1081. doi: 10.1111/jfb.13803. [PMID: 30242832]
  • Peter Santer, Ervin Pejo, Yan Feng, Wei Chao, Douglas E Raines. Cyclopropyl-methoxycarbonyl Metomidate: Studies in a Lipopolysaccharide Inflammatory Model of Sepsis. Anesthesiology. 2015 Aug; 123(2):368-76. doi: 10.1097/aln.0000000000000721. [PMID: 26035348]
  • Jason A Campagna, Kevin Pojasek, David Grayzel, John Randle, Douglas E Raines. Advancing novel anesthetics: pharmacodynamic and pharmacokinetic studies of cyclopropyl-methoxycarbonyl metomidate in dogs. Anesthesiology. 2014 Dec; 121(6):1203-16. doi: 10.1097/aln.0000000000000416. [PMID: 25170571]
  • Anders Karlsson, Bjørn Olav Rosseland, Jean-Charles Massabuau, Anders Kiessling. Pre-anaesthetic metomidate sedation delays the stress response after caudal artery cannulation in Atlantic cod (Gadus morhua). Fish physiology and biochemistry. 2012 Apr; 38(2):401-11. doi: 10.1007/s10695-011-9516-x. [PMID: 21638007]
  • Henrik Sundh, Bjørn Olav Kvamme, Frode Fridell, Rolf Erik Olsen, Tim Ellis, Geir Lasse Taranger, Kristina Sundell. Intestinal barrier function of Atlantic salmon (Salmo salar L.) post smolts is reduced by common sea cage environments and suggested as a possible physiological welfare indicator. BMC physiology. 2010 Nov; 10(?):22. doi: 10.1186/1472-6793-10-22. [PMID: 21062437]
  • Pål A Olsvik, Kai K Lie, Ernst M Hevrøy. Do anesthetics and sampling strategies affect transcription analysis of fish tissues?. BMC molecular biology. 2007 Jun; 8(?):48. doi: 10.1186/1471-2199-8-48. [PMID: 17559653]
  • Damian P Bright, Sara D Adham, Lucienne C J M Lemaire, Rodrigo Benavides, Marco Gruss, Graham W Taylor, Edward H Smith, Nicholas P Franks. Identification of anesthetic binding sites on human serum albumin using a novel etomidate photolabel. The Journal of biological chemistry. 2007 Apr; 282(16):12038-47. doi: 10.1074/jbc.m700479200. [PMID: 17311911]
  • Vladimir Krejci, Luzius B Hiltebrand, Stephan M Jakob, Jukka Takala, Gisli H Sigurdsson. Vasopressin in septic shock: effects on pancreatic, renal, and hepatic blood flow. Critical care (London, England). 2007; 11(6):R129. doi: 10.1186/cc6197. [PMID: 18078508]
  • Kenneth B Davis, Brian C Small. Rates of cortisol increase and decrease in channel catfish and sunshine bass exposed to an acute confinement stressor. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. 2006 May; 143(1):134-9. doi: 10.1016/j.cbpc.2006.01.003. [PMID: 16466968]
  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • M K Hansen, U Nymoen, T E Horsberg. Pharmacokinetic and pharmacodynamic properties of metomidate in turbot (Scophthalmus maximus) and halibut (Hippoglossus hippoglossus). Journal of veterinary pharmacology and therapeutics. 2003 Apr; 26(2):95-103. doi: 10.1046/j.1365-2885.2003.00454.x. [PMID: 12667178]
  • H Gerard, P L Sensky, D M Broom, S Perremans, R Geers. Influences of type of anaesthesia on cortisol, beta-endorphin and heart rate in pigs. Veterinary research. 1996; 27(3):219-26. doi: NULL. [PMID: 8767884]