UNII:59JV96YTXV (BioDeep_00000694134)

   


代谢物信息卡片


Midodrine (hydrochloride)

化学式: C12H19ClN2O4 (290.1033284)
中文名称: 盐酸米多君-d6, 盐酸米多君
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: COC1=CC(=C(C=C1)OC)C(CNC(=O)CN)O.Cl
InChI: 1H

描述信息

D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
C78272 - Agent Affecting Nervous System > C29747 - Adrenergic Agent > C87053 - Adrenergic Agonist
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents > D000322 - Adrenergic Agonists
D002317 - Cardiovascular Agents > D014662 - Vasoconstrictor Agents
Midodrine hydrochloride ((±)-Midodrine hydrochloride) is an α1-receptor agonist, for the treatment of dysautonomia and orthostatic hypotension.

同义名列表

4 个代谢物同义名

Midodrine (hydrochloride); Midodrine hydrochloride; UNII:59JV96YTXV; (±)-Midodrine (hydrochloride)



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Praveen Sharma, Pankaj Puri, Naresh Bansal, Vikas Singla, Ashish Kumar, Anil Anikhindi ShriHari, Anil Arora. Midodrine and albumin versus albumin alone for the secondary prophylaxis of acute kidney injury in a patient with cirrhosis and ascites. European journal of gastroenterology & hepatology. 2021 12; 33(1S Suppl 1):e499-e504. doi: 10.1097/meg.0000000000002154. [PMID: 34034268]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Xiaolan Ye, Bai Ling, Jian Wu, Shujuan Wu, Yan Ren, Hongjuan Zhang, Feifeng Song, Zixue Xuan, Maosheng Chen. Case report: severe myoclonus associated with oral midodrine treatment for hypotension. Medicine. 2020 Oct; 99(40):e21533. doi: 10.1097/md.0000000000021533. [PMID: 33019383]
  • Mary J Thomson, Arthur Taylor, Pratima Sharma, Anna S Lok, Elliot B Tapper. Limited Progress in Hepatorenal Syndrome (HRS) Reversal and Survival 2002-2018: A Systematic Review and Meta-Analysis. Digestive diseases and sciences. 2020 05; 65(5):1539-1548. doi: 10.1007/s10620-019-05858-2. [PMID: 31571102]
  • Amruta Tripathy, Rituparna Maiti, Monalisa Jena, Archana Mishra, Anand Srinivasan. Effect of alpha agonists on the prevention of postparacentesis circulatory dysfunction in patients with refractory or recurrent ascites: a meta-analysis. European journal of gastroenterology & hepatology. 2020 03; 32(3):303-311. doi: 10.1097/meg.0000000000001594. [PMID: 31688312]
  • Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. Molecular pharmacology. 2019 11; 96(5):629-640. doi: 10.1124/mol.119.115964. [PMID: 31515284]
  • Yeliz Demir. The behaviour of some antihypertension drugs on human serum paraoxonase-1: an important protector enzyme against atherosclerosis. The Journal of pharmacy and pharmacology. 2019 Oct; 71(10):1576-1583. doi: 10.1111/jphp.13144. [PMID: 31347707]
  • Nikhil Cordeiro, Sushilkumar Satish Gupta, Daniel Lindsay, Chanaka Seneviratne, Guy Kulbak, Yizhak Kupfer. Midodrine: Associated Bradycardia. American journal of therapeutics. 2019 Sep; 26(5):e655-e656. doi: 10.1097/mjt.0000000000000856. [PMID: 31498780]
  • Victoria Treasure, Royce P Vincent, David R Taylor. Falsely elevated plasma 3-methoxytyramine in a patient receiving midodrine therapy. Annals of clinical biochemistry. 2019 05; 56(3):415-416. doi: 10.1177/0004563218818199. [PMID: 30813742]
  • Rupesh Raina, Stephanie Lam, Hershita Raheja, Vinod Krishnappa, Daljit Hothi, Andrew Davenport, Deepa Chand, Gaurav Kapur, Franz Schaefer, Sidharth Kumar Sethi, Mignon McCulloch, Arvind Bagga, Timothy Bunchman, Bradley A Warady. Pediatric intradialytic hypotension: recommendations from the Pediatric Continuous Renal Replacement Therapy (PCRRT) Workgroup. Pediatric nephrology (Berlin, Germany). 2019 05; 34(5):925-941. doi: 10.1007/s00467-018-4190-1. [PMID: 30734850]
  • Ayman Yosry, Zeinab A Soliman, Rasha Eletreby, Iman Hamza, Alaa Ismail, Mohammad A Elkady. Oral midodrine is comparable to albumin infusion in cirrhotic patients with refractory ascites undergoing large-volume paracentesis: results of a pilot study. European journal of gastroenterology & hepatology. 2019 03; 31(3):345-351. doi: 10.1097/meg.0000000000001277. [PMID: 30312183]
  • Beatrice Drambarean, Paula Bielnicka, Ali Alobaidi. Midodrine treatment in a patient with treprostinil-induced hypotension receiving hemodialysis. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. 2019 Jan; 76(1):13-16. doi: 10.1093/ajhp/zxy001. [PMID: 31381098]
  • Elsa Solà, Cristina Solé, Macarena Simón-Talero, Marta Martín-Llahí, José Castellote, Rita Garcia-Martínez, Rebeca Moreira, Maria Torrens, Francisca Márquez, Núria Fabrellas, Gloria de Prada, Patrícia Huelin, Eva Lopez Benaiges, Meritxell Ventura, Marcela Manríquez, André Nazar, Xavier Ariza, Pilar Suñé, Isabel Graupera, Elisa Pose, Jordi Colmenero, Marco Pavesi, Mónica Guevara, Miquel Navasa, Xavier Xiol, Joan Córdoba, Victor Vargas, Pere Ginès. Midodrine and albumin for prevention of complications in patients with cirrhosis awaiting liver transplantation. A randomized placebo-controlled trial. Journal of hepatology. 2018 12; 69(6):1250-1259. doi: 10.1016/j.jhep.2018.08.006. [PMID: 30138685]
  • April A Pottebaum, Jennifer C Hagopian, Daniel C Brennan, Ara Gharabagi, Timothy A Horwedel. Influence of pretransplant midodrine use on outcomes after kidney transplantation. Clinical transplantation. 2018 09; 32(9):e13366. doi: 10.1111/ctr.13366. [PMID: 30076650]
  • Holly Emms, George Farah, Brian Shine, Chris Boot, Barry Toole, Martin McFadden, Leo Lam, Zong-Quan Ou, Gerald Woollard, Hima Madhavaram, Campbell Kyle, Ashley B Grossman. Falsely elevated plasma metanephrine in patients taking midodrine. Annals of clinical biochemistry. 2018 Jul; 55(4):509-515. doi: 10.1177/0004563218755817. [PMID: 29357678]
  • Isabelle Colle, Pierre-François Laterre. Hepatorenal syndrome: the clinical impact of vasoactive therapy. Expert review of gastroenterology & hepatology. 2018 Feb; 12(2):173-188. doi: 10.1080/17474124.2018.1417034. [PMID: 29258378]
  • Niels Klarskov, Dirk Cerneus, William Sawyer, Donald Newgreen, Olivier van Till, Gunnar Lose. The effect of single oral doses of duloxetine, reboxetine, and midodrine on the urethral pressure in healthy female subjects, using urethral pressure reflectometry. Neurourology and urodynamics. 2018 01; 37(1):244-249. doi: 10.1002/nau.23282. [PMID: 28419624]
  • Steven M Brunelli, Dena E Cohen, Gilbert Marlowe, David Van Wyck. The Impact of Midodrine on Outcomes in Patients with Intradialytic Hypotension. American journal of nephrology. 2018; 48(5):381-388. doi: 10.1159/000494806. [PMID: 30423552]
  • Nitish Rai, Baljinder Singh, Akash Singh, Rajesh Vijayvergiya, Navneet Sharma, Ashish Bhalla, Virendra Singh. Midodrine and tolvaptan in patients with cirrhosis and refractory or recurrent ascites: a randomised pilot study. Liver international : official journal of the International Association for the Study of the Liver. 2017 03; 37(3):406-414. doi: 10.1111/liv.13250. [PMID: 27614145]
  • Amr S Hanafy, Ahmad M Hassaneen. Rifaximin and midodrine improve clinical outcome in refractory ascites including renal function, weight loss, and short-term survival. European journal of gastroenterology & hepatology. 2016 Dec; 28(12):1455-1461. doi: 10.1097/meg.0000000000000743. [PMID: 27622998]
  • Tien Dong, Andrew Aronsohn, K Gautham Reddy, Helen S Te. Rifaximin Decreases the Incidence and Severity of Acute Kidney Injury and Hepatorenal Syndrome in Cirrhosis. Digestive diseases and sciences. 2016 12; 61(12):3621-3626. doi: 10.1007/s10620-016-4313-0. [PMID: 27655104]
  • Daxesh P Patel, Sneha Nair, Bhanubhai N Suhagia, Bhargav M Patel. A novel, sensitive and selective method of UPLC/MS-MS for rapid simultaneous determination of midodrine and its active metabolite desglymidodrine in human plasma: Application to support bioequivalence study in healthy human volunteers. Journal of pharmaceutical and biomedical analysis. 2016 Nov; 131(?):355-363. doi: 10.1016/j.jpba.2016.09.005. [PMID: 27639073]
  • Gaetano Bertino, Graziella Privitera, Francesco Purrello, Shirin Demma, Emanuele Crisafulli, Luisa Spadaro, Nikolaos Koukias, Emmanuel A Tsochatzis. Emerging hepatic syndromes: pathophysiology, diagnosis and treatment. Internal and emergency medicine. 2016 Oct; 11(7):905-16. doi: 10.1007/s11739-016-1478-7. [PMID: 27273018]
  • Florence Wong. Diagnosing and treating renal disease in cirrhotic patients. Minerva gastroenterologica e dietologica. 2016 Sep; 62(3):253-66. doi: . [PMID: 27096702]
  • Tary A Salman, Ahmed M Edrees, Hala H El-Said, Osama L El-Abd, Gasser I El-Azab. Effect of different therapeutic modalities on systemic, renal, and hepatic hemodynamics and short-term outcomes in cirrhotic patients with spontaneous bacterial peritonitis. European journal of gastroenterology & hepatology. 2016 Jul; 28(7):777-85. doi: 10.1097/meg.0000000000000635. [PMID: 27097354]
  • Ryoko Kurihara, Katsunori Imazumi, Hajime Takamatsu, Kenichiro Ishizu, Taiji Yoshino, Noriyuki Masuda. Effect of Selective Prostaglandin E2 EP2 Receptor Agonist CP-533,536 on Voiding Efficiency in Rats with Midodrine-Induced Functional Urethral Obstruction. Lower urinary tract symptoms. 2016 May; 8(2):130-5. doi: 10.1111/luts.12080. [PMID: 27111626]
  • Tarek Alhamad, Daniel C Brennan, Zaid Brifkani, Huiling Xiao, Mark A Schnitzler, Vikas R Dharnidharka, David Axelrod, Dorry L Segev, Krista L Lentine. Pretransplant Midodrine Use: A Newly Identified Risk Marker for Complications After Kidney Transplantation. Transplantation. 2016 05; 100(5):1086-93. doi: 10.1097/tp.0000000000001113. [PMID: 26950718]
  • Giovanni Sansoè, Manuela Aragno, Raffaella Mastrocola, Maurizio Parola. Dose-dependency of clonidine's effects in ascitic cirrhotic rats: comparison with α1-adrenergic agonist midodrine. Liver international : official journal of the International Association for the Study of the Liver. 2016 Feb; 36(2):205-11. doi: 10.1111/liv.12905. [PMID: 26121993]
  • Ahmed Ali, Samar Farid, Mona Amin, Mohamed Kassem, Nouman Al-Garem, Medhat Al-Ghobashy. Comparative Clinical Pharmacokinetics of Midodrine and Its Active Metabolite Desglymidodrine in Cirrhotic Patients with Tense Ascites Versus Healthy Volunteers. Clinical drug investigation. 2016 Feb; 36(2):147-55. doi: 10.1007/s40261-015-0359-6. [PMID: 26597181]
  • Ting Ting Guo, Yue Yang, Yang Song, Yu Ren, Zhi Xin Liu, Gang Cheng. Effects of midodrine in patients with ascites due to cirrhosis: Systematic review and meta-analysis. Journal of digestive diseases. 2016 Jan; 17(1):11-9. doi: 10.1111/1751-2980.12304. [PMID: 26630543]
  • Marta Cavallin, Patrick S Kamath, Manuela Merli, Silvano Fasolato, Pierluigi Toniutto, Francesco Salerno, Mauro Bernardi, Roberto Giulio Romanelli, Cosimo Colletta, Freddy Salinas, Antonio Di Giacomo, Lorenzo Ridola, Ezio Fornasiere, Paolo Caraceni, Filippo Morando, Salvatore Piano, Angelo Gatta, Paolo Angeli. Terlipressin plus albumin versus midodrine and octreotide plus albumin in the treatment of hepatorenal syndrome: A randomized trial. Hepatology (Baltimore, Md.). 2015 Aug; 62(2):567-74. doi: 10.1002/hep.27709. [PMID: 25644760]
  • Ahmed A Ali, Medhat A Al-Ghobashy, Samar F Farid, Mohamed A Kassem. Development and validation of LC-MS/MS assay for the determination of the prodrug Midodrine and its active metabolite Desglymidodrine in plasma of ascitic patients: Application to individualized therapy and comparative pharmacokinetics. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Jun; 991(?):34-40. doi: 10.1016/j.jchromb.2015.03.032. [PMID: 25910235]
  • Hongxia Li, Fengwen Zhang, Yuli Wang, Ping Liu, Chunyu Zhang, Xueli Feng, Junbao Du, Hongfang Jin. [Predictive value of baseline plasma midregional fragment of pro-adrenomedullin level on long-term outcome of postural tachycardia syndrome children treated with midodrine hydrochloride]. Zhonghua xin xue guan bing za zhi. 2015 Jun; 43(6):507-10. doi: NULL. [PMID: 26420118]
  • Bernard E Leduc, Christine Fournier, Géraldine Jacquemin, Yves Lepage, Bernard Vinet, Pierre-Olivier Hétu, Miguel Chagnon. Midodrine in patients with spinal cord injury and anejaculation: A double-blind randomized placebo-controlled pilot study. The journal of spinal cord medicine. 2015 Jan; 38(1):57-62. doi: 10.1179/2045772314y.0000000225. [PMID: 24969635]
  • Juan Carlos Q Velez, Manish Kadian, Margarita Taburyanskaya, Nicole M Bohm, Tracie A Delay, Nithin Karakala, Don C Rockey, Paul J Nietert, Andrew J Goodwin, Timothy P Whelan. Hepatorenal Acute Kidney Injury and the Importance of Raising Mean Arterial Pressure. Nephron. 2015; 131(3):191-201. doi: 10.1159/000441151. [PMID: 26485256]
  • Ahmed Ali, Samar Farid, Mona Amin, Mohamed Kassem, Nouman Al-Garem. Clinical study on the therapeutic role of midodrine in non azotemic cirrhotic patients with tense ascites: a double-blind, placebo-controlled, randomized trial. Hepato-gastroenterology. 2014 Oct; 61(135):1915-24. doi: . [PMID: 25713888]
  • Natsumi Tanabe, Koki Takane, Keitaro Yokoyama, Yudo Tanno, Izumi Yamamoto, Ichiro Ohkido, Takashi Yokoo. Dialysate temperature adjustment as an effective treatment for baroreflex failure syndrome in hemodialysis patient. BMC nephrology. 2014 Sep; 15(?):151. doi: 10.1186/1471-2369-15-151. [PMID: 25231766]
  • Juan Zhao, Chaoshu Tang, Hongfang Jin, Junbao Du. Plasma copeptin and therapeutic effectiveness of midodrine hydrochloride on postural tachycardia syndrome in children. The Journal of pediatrics. 2014 Aug; 165(2):290-294.e1. doi: 10.1016/j.jpeds.2014.04.032. [PMID: 24857518]
  • Hassan Hamdy, Ahmed A ElBaz, Ahmed Hassan, Omayma Hassanin. Comparison of midodrine and albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients: a randomized pilot study. Journal of clinical gastroenterology. 2014 Feb; 48(2):184-8. doi: 10.1097/mcg.0b013e31829ae376. [PMID: 23842215]
  • N Hadiji, R Benbouzid, J G Previnaire, C Leblond, R Mieusset, M Enjalbert, J M Soler. [Evaluation of the management of erectile and ejaculatory dysfunction in a series of 90 patients with spinal cord injuries]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie. 2013 Dec; 23(17):1489-93. doi: 10.1016/j.purol.2013.08.316. [PMID: 24286550]
  • Virendra Singh, Ajay Singh, Baljinder Singh, Rajesh Vijayvergiya, Navneet Sharma, Anchal Ghai, Ashish Bhalla. Midodrine and clonidine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study. The American journal of gastroenterology. 2013 Apr; 108(4):560-7. doi: 10.1038/ajg.2013.9. [PMID: 23419385]
  • Amanda B Hassinger, Sudha Garimella. Refractory hypotension after bilateral nephrectomies in a Denys-Drash patient with phenylketonuria. Pediatric nephrology (Berlin, Germany). 2013 Feb; 28(2):345-8. doi: 10.1007/s00467-012-2311-9. [PMID: 22992984]
  • Khurram Bari, Cecilia Miñano, Martha Shea, Irteza B Inayat, Hashem J Hashem, Hochong Gilles, Douglas Heuman, Guadalupe Garcia-Tsao. The combination of octreotide and midodrine is not superior to albumin in preventing recurrence of ascites after large-volume paracentesis. Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association. 2012 Oct; 10(10):1169-75. doi: 10.1016/j.cgh.2012.06.027. [PMID: 22801062]
  • Roberta A Thomas, Marshall S Scicchitano, Rosanna C Mirabile, Nancy T Chau, Kendall S Frazier, Heath C Thomas. MicroRNA changes in rat mesentery and serum associated with drug-induced vascular injury. Toxicology and applied pharmacology. 2012 Aug; 262(3):310-20. doi: 10.1016/j.taap.2012.05.009. [PMID: 22627061]
  • Kurt Kimpinski, Juan J Figueroa, Wolfgang Singer, David M Sletten, Valeria Iodice, Paola Sandroni, Philip R Fischer, Tonette L Opfer-Gehrking, Jade A Gehrking, Phillip A Low. A prospective, 1-year follow-up study of postural tachycardia syndrome. Mayo Clinic proceedings. 2012 Aug; 87(8):746-52. doi: 10.1016/j.mayocp.2012.02.020. [PMID: 22795533]
  • Fengwen Zhang, Xueying Li, Todd Ochs, Li Chen, Ying Liao, Chaoshu Tang, Hongfang Jin, Junbao Du. Midregional pro-adrenomedullin as a predictor for therapeutic response to midodrine hydrochloride in children with postural orthostatic tachycardia syndrome. Journal of the American College of Cardiology. 2012 Jul; 60(4):315-20. doi: 10.1016/j.jacc.2012.04.025. [PMID: 22813609]
  • Virendra Singh, Sahdeb P Dhungana, Baljinder Singh, Rajesh Vijayverghia, Chander K Nain, Navneet Sharma, Ashish Bhalla, Pramod K Gupta. Midodrine in patients with cirrhosis and refractory or recurrent ascites: a randomized pilot study. Journal of hepatology. 2012 Feb; 56(2):348-54. doi: 10.1016/j.jhep.2011.04.027. [PMID: 21749847]
  • Marco Olivera-Martinez, Marco Olivera Martinez, Harlan Sayles, Renuga Vivekanandan, Sharlene D' Souza, Marius C Florescu. Hepatorenal syndrome: are we missing some prognostic factors?. Digestive diseases and sciences. 2012 Jan; 57(1):210-4. doi: 10.1007/s10620-011-1861-1. [PMID: 21850494]
  • Jill M Wecht, Miroslav Radulovic, Dwindally Rosado-Rivera, Run-Lin Zhang, Michael F LaFountaine, William A Bauman. Orthostatic effects of midodrine versus L-NAME on cerebral blood flow and the renin-angiotensin-aldosterone system in tetraplegia. Archives of physical medicine and rehabilitation. 2011 Nov; 92(11):1789-95. doi: 10.1016/j.apmr.2011.03.022. [PMID: 21762873]
  • John P Rice, Catherine Skagen, Adnan Said. Liver transplant outcomes for patients with hepatorenal syndrome treated with pretransplant vasoconstrictors and albumin. Transplantation. 2011 May; 91(10):1141-7. doi: 10.1097/tp.0b013e31821690bf. [PMID: 21544034]
  • Shang-Jin Shi, Steven H Platts, Michael G Ziegler, Janice V Meck. Effects of promethazine and midodrine on orthostatic tolerance. Aviation, space, and environmental medicine. 2011 Jan; 82(1):9-12. doi: 10.3357/asem.2888.2011. [PMID: 21235099]
  • V L Misra, R Vuppalanchi, D Jones, M Hamman, P Y Kwo, C Kahi, N Chalasani. The effects of midodrine on the natriuretic response to furosemide in cirrhotics with ascites. Alimentary pharmacology & therapeutics. 2010 Oct; 32(8):1044-50. doi: 10.1111/j.1365-2036.2010.04426.x. [PMID: 20937051]
  • Suzanne M Bergman. Hemodialysis in hypotensive heart failure using midodrine. The American journal of the medical sciences. 2009 Dec; 338(6):470-3. doi: 10.1097/maj.0b013e3181b7efa7. [PMID: 19875951]
  • C Alessandria, W Debernardi-Venon, M Carello, S Ceretto, M Rizzetto, A Marzano. Midodrine in the prevention of hepatorenal syndrome type 2 recurrence: a case-control study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver. 2009 Apr; 41(4):298-302. doi: 10.1016/j.dld.2008.09.014. [PMID: 19158001]
  • S K Baker, C Morillo, S Vernino. Autoimmune autonomic ganglionopathy with late-onset encephalopathy. Autonomic neuroscience : basic & clinical. 2009 Mar; 146(1-2):29-32. doi: 10.1016/j.autneu.2008.10.016. [PMID: 19028442]
  • Puneeta Tandon, Ross T Tsuyuki, Lesley Mitchell, Michael Hoskinson, Mang M Ma, Winnie W Wong, Andrew L Mason, Klaus Gutfreund, Vincent G Bain. The effect of 1 month of therapy with midodrine, octreotide-LAR and albumin in refractory ascites: a pilot study. Liver international : official journal of the International Association for the Study of the Liver. 2009 Feb; 29(2):169-74. doi: 10.1111/j.1478-3231.2008.01778.x. [PMID: 18492024]
  • Maxime Lamarre-Cliche, Patrick du Souich, Jacques de Champlain, Pierre Larochelle. Pharmacokinetic and pharmacodynamic effects of midodrine on blood pressure, the autonomic nervous system, and plasma natriuretic peptides: a prospective, randomized, single-blind, two-period, crossover, placebo-controlled study. Clinical therapeutics. 2008 Sep; 30(9):1629-38. doi: 10.1016/j.clinthera.2008.09.001. [PMID: 18840368]
  • Beate Appenrodt, Andrea Wolf, Frank Grünhage, Jonel Trebicka, Michael Schepke, Christian Rabe, Frank Lammert, Tilman Sauerbruch, J Heller. Prevention of paracentesis-induced circulatory dysfunction: midodrine vs albumin. A randomized pilot study. Liver international : official journal of the International Association for the Study of the Liver. 2008 Aug; 28(7):1019-25. doi: 10.1111/j.1478-3231.2008.01734.x. [PMID: 18410283]
  • Virendra Singh, Prashant C Dheerendra, Baljinder Singh, Chander K Nain, Divya Chawla, Navneet Sharma, Ashish Bhalla, Sushil K Mahi. Midodrine versus albumin in the prevention of paracentesis-induced circulatory dysfunction in cirrhotics: a randomized pilot study. The American journal of gastroenterology. 2008 Jun; 103(6):1399-405. doi: 10.1111/j.1572-0241.2008.01787.x. [PMID: 18547224]
  • Sofia Rubinstein, Moshe Haimov, Michael J Ross. Midodrine-induced vascular ischemia in a hemodialysis patient: a case report and literature review. Renal failure. 2008; 30(8):808-12. doi: 10.1080/08860220802249025. [PMID: 18791956]
  • Subramanian Vaidyanathan, Bakul M Soni, Peter L Hughes. Midodrine: insidious development of urologic adverse effects in patients with spinal cord injury: a report of 2 cases. Advances in therapy. 2007 Jul; 24(4):712-20. doi: 10.1007/bf02849965. [PMID: 17901021]
  • Georgios Kalambokis, Andreas Fotopoulos, Michalis Economou, Konstantinos Pappas, Epameinondas V Tsianos. Effects of a 7-day treatment with midodrine in non-azotemic cirrhotic patients with and without ascites. Journal of hepatology. 2007 Feb; 46(2):213-21. doi: 10.1016/j.jhep.2006.09.012. [PMID: 17156883]
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