Iodo-gen (BioDeep_00000692179)

   


代谢物信息卡片


1,3,4,6-Tetrachloro-3a,6a-diphenylglycouril

化学式: C16H10Cl4N4O2 (429.955784)
中文名称: 1,3,4,6-四氯-3α,6α-二苯基甘油
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C(C=C1)C23C(N(C(=O)N2Cl)Cl)(N(C(=O)N3Cl)Cl)C4=CC=CC=C4
InChI: InChI=1S/C16H10Cl4N4O2/c17-21-13(25)23(19)16(12-9-5-2-6-10-12)15(21,11-7-3-1-4-8-11)22(18)14(26)24(16)20/h1-10H

描述信息

D019995 - Laboratory Chemicals > D007202 - Indicators and Reagents

同义名列表

2 个代谢物同义名

1,3,4,6-Tetrachloro-3a,6a-diphenylglycouril; Iodo-gen



数据库引用编号

2 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Jianqing Chen, Mengmeng Wang, Alison Joyce, David DeFranco, Mania Kavosi, Xin Xu, Denise M O'Hara. Comparison of succinimidyl [(125)I]iodobenzoate with iodogen iodination methods to study pharmacokinetics and ADME of biotherapeutics. Pharmaceutical research. 2014 Oct; 31(10):2810-21. doi: 10.1007/s11095-014-1378-3. [PMID: 24844406]
  • Marlein Miranda Cona, Junjie Li, Feng Chen, Yuanbo Feng, Yeranddy Aguiar Alpizar, Florent Vanstapel, Karel Talavera, Peter de Witte, Alfons Verbruggen, Ziping Sun, Raymond Oyen, Yicheng Ni. A safety study on single intravenous dose of tetrachloro-diphenyl glycoluril [iodogen] dissolved in dimethyl sulphoxide (DMSO). Xenobiotica; the fate of foreign compounds in biological systems. 2013 Aug; 43(8):730-7. doi: 10.3109/00498254.2012.756559. [PMID: 23294333]
  • Ying Xie, Gaoren Zhong, Hongbing He, Guorong Fan, Yutian Wu. Pharmacokinetics, tissue distribution and excretion of porcine fibrinogen after intraperitoneal injection of a porcine-derived fibrin glue to rats. Journal of pharmaceutical and biomedical analysis. 2011 Jan; 54(1):148-53. doi: 10.1016/j.jpba.2010.07.048. [PMID: 20828964]
  • Chenguang Cai, Jinjing Che, Long Xu, Qiang Guo, Yirong Kong, Ling Fu, Junjie Xu, Yuanguo Cheng, Wei Chen. Tumor endothelium marker-8 based decoys exhibit superiority over capillary morphogenesis protein-2 based decoys as anthrax toxin inhibitors. PloS one. 2011; 6(6):e20646. doi: 10.1371/journal.pone.0020646. [PMID: 21674060]
  • Vesa Kirjavainen, Hanna Jarva, Marta Biedzka-Sarek, Anna M Blom, Mikael Skurnik, Seppo Meri. Yersinia enterocolitica serum resistance proteins YadA and ail bind the complement regulator C4b-binding protein. PLoS pathogens. 2008 Aug; 4(8):e1000140. doi: 10.1371/journal.ppat.1000140. [PMID: 18769718]
  • Beom Soo Shin, Jin Hyuk Seo, Man-Wook Hur, Min-Nyung Lee, Sun Dong Yoo. Pharmacokinetics of GST-TatdMt, a recombinant fusion protein possessing potent anti-obesity activity, in mice. Archives of pharmacal research. 2007 Sep; 30(9):1162-7. doi: 10.1007/bf02980253. [PMID: 17958336]
  • Beom Soo Shin, Chul Hwan Kim, Min-Nyung Lee, Man-Wook Hur, Kang Choon Lee, Yu Seok Youn, Sun Dong Yoo. Pharmacokinetics of 125I-GST-TatdMt, a recombinant fusion protein possessing potent anti-obesity activity, after intravenous, nasal, oral, and subcutaneous administration. Regulatory peptides. 2007 Apr; 140(1-2):74-80. doi: 10.1016/j.regpep.2006.11.013. [PMID: 17175039]
  • Samuel Samnick, Ursula Nestle, Mathias Wagner, Thierry Fozing, Andrea Schaefer, Michael D Menger, Carl-Martin Kirsch. Validation of 8-[123I]iodo-L-1,2,3,4-tetrahydro-7-hydroxyisoquinoline-3-carboxylic acid as an imaging agent for prostate cancer in experimental models of human prostate cancer. Nuclear medicine and biology. 2007 Jan; 34(1):99-107. doi: 10.1016/j.nucmedbio.2006.10.013. [PMID: 17210466]
  • Devin B Tesar, Noreen E Tiangco, Pamela J Bjorkman. Ligand valency affects transcytosis, recycling and intracellular trafficking mediated by the neonatal Fc receptor. Traffic (Copenhagen, Denmark). 2006 Sep; 7(9):1127-42. doi: 10.1111/j.1600-0854.2006.00457.x. [PMID: 17004319]
  • Beom Soo Shin, Chul Hwan Kim, Yun Sik Jun, Eun Hye Park, Man-Wook Hur, Kang Choon Lee, Yu Seok Yoon, Min-Nyung Lee, Sun Dong Yoo. Dose-linear pharmacokinetics, tissue distribution, and excretion of a recombinant fusion protein 125I-GST-TatdMt possessing potent anti-obesity activity. Regulatory peptides. 2005 Jul; 129(1-3):25-30. doi: 10.1016/j.regpep.2005.01.010. [PMID: 15927694]
  • J R Romero, R Martínez, O Fresnedo, B Ochoa. Comparison of two methods for radioiodination on the oxidizability properties of low density lipoprotein. Journal of physiology and biochemistry. 2001 Dec; 57(4):291-301. doi: 10.1007/bf03179823. [PMID: 12005032]
  • G W Visser, R P Klok, J W Gebbinck, T ter Linden, G A van Dongen, C F Molthoff. Optimal quality (131)I-monoclonal antibodies on high-dose labeling in a large reaction volume and temporarily coating the antibody with IODO-GEN. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2001 Mar; 42(3):509-19. doi: NULL. [PMID: 11337531]
  • B A Abreu Filho, B P Dias Filho, A B Vermelho, S I Jankevicius, J V Jankevicius, R L dos Santos. Surface component characterization as taxonomic tools for Phytomonas spp identification. Parasitology research. 2001 Feb; 87(2):138-44. doi: 10.1007/pl00008566. [PMID: 11206111]
  • H Wolf, F Marschall, N Scheffold, M Clausen, M Schramm, E Henze. Iodine-123 labelling of atrial natriuretic peptide and its analogues: initial results. European journal of nuclear medicine. 1993 Apr; 20(4):297-301. doi: 10.1007/bf00169804. [PMID: 8491221]
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  • R J Aitken, M J Hulme, C J Henderson, T B Hargreave, A Ross. Analysis of the surface labelling characteristics of human spermatozoa and the interaction with anti-sperm antibodies. Journal of reproduction and fertility. 1987 Jul; 80(2):473-85. doi: 10.1530/jrf.0.0800473. [PMID: 2443696]
  • P M Kleveland, S E Haugen, H L Waldum. The preparation of bioactive 125I-gastrin, using Iodo-gen as oxidizing agent, and the use of this tracer in receptor studies. Scandinavian journal of gastroenterology. 1985 Jun; 20(5):569-76. doi: 10.3109/00365528509089698. [PMID: 2992067]
  • D R Jury, J F Speed, P J Dunn. Urinary albumin radioimmunoassay using a solid phase second antibody and solid phase albumin iodination. Clinica chimica acta; international journal of clinical chemistry. 1985 May; 148(1):63-7. doi: 10.1016/0009-8981(85)90301-8. [PMID: 4006224]
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  • T B Schulz, R Jorde, H L Waldum, P G Burhol. Preparation of 125I-labeled gastric inhibitory polypeptide, using water-insoluble 1,2,4,6-tetrachloro-3 alpha,6 alpha-diphenylglycoluril (Iodo-gen) as the oxidizing agent. Scandinavian journal of gastroenterology. 1982 Apr; 17(3):379-82. doi: 10.3109/00365528209182071. [PMID: 7134864]
  • R Heath, S Jeffery, N Carter. Radioimmunoassay of human muscle carbonic anhydrase III in dystrophic states. Clinica chimica acta; international journal of clinical chemistry. 1982 Mar; 119(3):299-305. doi: 10.1016/0009-8981(82)90343-6. [PMID: 6802521]
  • P G Burhol, T G Jenssen, I Lygren, T B Schulz, R Jorde, H L Waldum. Iodination with Iodo-gen and radioimmunoassay of cholecystokinin (CCK) in acidified plasma, CCK release, and molecular CCK components in man. Digestion. 1982; 23(3):156-68. doi: 10.1159/000198723. [PMID: 7106417]
  • L C Knight, A Z Budzynski, S A Olexa. Radiolabeling of fibrinogen using the iodogen technique. Thrombosis and haemostasis. 1981 Oct; 46(3):593-6. doi: 10.1055/s-0038-1653425. [PMID: 7314054]