Chlorotrifluoroethylene (BioDeep_00000690451)
代谢物信息卡片
fluorolube grease, gr-362
化学式: C2ClF3 (115.9640626)
中文名称: 聚三氟氯乙烯, 三氟氯乙烯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C(=C(F)Cl)(F)F
InChI: InChI=1S/C2ClF3/c3-1(4)2(5)6
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Georges Morel, Masarin Ban, Pierre Bonnet, Danièle Zissu, Marie-Thérèse Brondeau. Effect of beta-naphthoflavone and phenobarbital on the nephrotoxicity of chlorotrifluoroethylene and 1,1-dichloro-2,2-difluoroethylene in the rat.
Journal of applied toxicology : JAT.
2005 Mar; 25(2):153-65. doi:
10.1002/jat.1048. [PMID: 15744758] - Alvaro Mata, Xiaowei Su, Aaron J Fleischman, Shuvo Roy, Bruce A Banks, Sharon K Miller, Ronald J Midura. Osteoblast attachment to a textured surface in the absence of exogenous adhesion proteins.
IEEE transactions on nanobioscience.
2003 Dec; 2(4):287-94. doi:
10.1109/tnb.2003.820268. [PMID: 15376920] - J C Lin, S L Tiong, C Y Chen. Surface characterization and platelet adhesion studies on fluorocarbons prepared by plasma-induced graft polymerization.
Journal of biomaterials science. Polymer edition.
2000; 11(7):701-14. doi:
10.1163/156856200743968. [PMID: 11011768] - E Tanaka, M W Anders. Biosynthesis of S-(2-chloro-1,1,2-trifluoroethyl)glutathione in rat and human hepatocytes and in Hep G2 cells.
Drug metabolism and disposition: the biological fate of chemicals.
1995 Jan; 23(1):48-54. doi:
NULL. [PMID: 7720524] - M Rahman, K Fujii, N Sato, O Yuge. Isoflurane increases the anaerobic metabolites of halothane.
Journal of applied toxicology : JAT.
1994 Jan; 14(1):43-6. doi:
10.1002/jat.2550140109. [PMID: 8157869] - M J Diaz, E Chinje, P Kentish, B Jarnot, M George, G G Gibson. Chlorotrifluoroethylene trimer and tetramer are inducers of the CYP4A subfamily.
Biochemical pharmacology.
1993 Sep; 46(6):1076-80. doi:
10.1016/0006-2952(93)90673-k. [PMID: 8216351] - J W Harris, W Dekant, M W Anders. In vivo detection and characterization of protein adducts resulting from bioactivation of haloethene cysteine S-conjugates by 19F NMR: chlorotrifluoroethene and tetrafluoroethene.
Chemical research in toxicology.
1992 Jan; 5(1):34-41. doi:
10.1021/tx00025a007. [PMID: 1581534] - N J DelRaso, C S Godin, C E Jones, H G Wall, D R Mattie, C D Flemming. Comparative hepatotoxicity of two polychlorotrifluoroethylenes (3.1 oils) and two chlorotrifluoroethylene (CTFE) oligomers in male Fischer 344 rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1991 Oct; 17(3):550-62. doi:
10.1016/0272-0590(91)90205-i. [PMID: 1794657] - J N Commandeur, G J Stijntjes, J Wijngaard, N P Vermeulen. Metabolism of L-cysteine S-conjugates and N-(trideuteroacetyl)-L-cysteine S-conjugates of four fluoroethylenes in the rat. Role of balance of deacetylation and acetylation in relation to the nephrotoxicity of mercapturic acids.
Biochemical pharmacology.
1991 Jun; 42(1):31-8. doi:
10.1016/0006-2952(91)90677-w. [PMID: 2069595] - P J Boogaard, J P Zoeteweij, T J van Berkel, J M van't Noordende, G J Mulder, J F Nagelkerke. Primary culture of proximal tubular cells from normal rat kidney as an in vitro model to study mechanisms of nephrotoxicity. Toxicity of nephrotoxicants at low concentrations during prolonged exposure.
Biochemical pharmacology.
1990 Apr; 39(8):1335-45. doi:
10.1016/0006-2952(90)90010-i. [PMID: 2322315] - G L Kennedy. Toxicology of fluorine-containing monomers.
Critical reviews in toxicology.
1990; 21(2):149-70. doi:
10.3109/10408449009089877. [PMID: 2083033] - D R Dohn, J R Leininger, L H Lash, A J Quebbemann, M W Anders. Nephrotoxicity of S-(2-chloro-1,1,2-trifluoroethyl)glutathione and S-(2-chloro-1,1,2-trifluoroethyl)-L-cysteine, the glutathione and cysteine conjugates of chlorotrifluoroethene.
The Journal of pharmacology and experimental therapeutics.
1985 Dec; 235(3):851-7. doi:
NULL. [PMID: 4078735] - C D Hassall, A J Gandolfi, R C Duhamel, K Brendel. The formation and biotransformation of cysteine conjugates of halogenated ethylenes by rabbit renal tubules.
Chemico-biological interactions.
1984 May; 49(3):283-97. doi:
10.1016/0009-2797(84)90103-0. [PMID: 6547077] - L A Buckley, J W Clayton, R B Nagle, A J Gandolfi. Chlorotrifluoroethylene nephrotoxicity in rats: a subacute study.
Fundamental and applied toxicology : official journal of the Society of Toxicology.
1982 Jul; 2(4):181-6. doi:
10.1016/s0272-0590(82)80044-4. [PMID: 7185615] - D W Bonhaus, A J Gandolfi. Conjugation and bioactivation of chlorotrifluoroethylene.
Life sciences.
1981 Dec; 29(23):2399-405. doi:
10.1016/0024-3205(81)90476-8. [PMID: 7321765] - A J Gandolfi, R B Nagle, J J Soltis, F H Plescia. Nephrotoxicity of halogenated vinyl cysteine compounds.
Research communications in chemical pathology and pharmacology.
1981 Aug; 33(2):249-61. doi:
NULL. [PMID: 7302373] - C L Potter, A J Gandolfi, R Nagle, J W Clayton. Effects of inhaled chlorotrifluoroethylene and hexafluoropropene on the rat kidney.
Toxicology and applied pharmacology.
1981 Jul; 59(3):431-40. doi:
10.1016/0041-008x(81)90295-7. [PMID: 7268767]