6-Chloropurine (BioDeep_00000686949)

   


代谢物信息卡片


6-Chloropurine

  化学式: C5H3ClN4 (154.0046)
中文名称: 6-氯嘌呤, 4-氯-1H-吡唑并[3,4-d]嘧啶
  谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(N1)C(=NC=N2)Cl
InChI: InChI=1S/C5H3ClN4/c6-4-3-5(9-1-7-3)10-2-8-4/h1-2H,(H,7,8,9,10)


描述信息

D000890 - Anti-Infective Agents > D000998 - Antiviral Agents
D000970 - Antineoplastic Agents

同义名列表

1 个代谢物同义名

6-Chloropurine



数据库引用编号

7 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Václav Mik, Lucie Szüčová, Lukáš Spíchal, Ondřej Plíhal, Jaroslav Nisler, Lenka Zahajská, Karel Doležal, Miroslav Strnad. N9-Substituted N⁶-[(3-methylbut-2-en-1-yl)amino]purine derivatives and their biological activity in selected cytokinin bioassays. Bioorganic & medicinal chemistry. 2011 Dec; 19(23):7244-51. doi: 10.1016/j.bmc.2011.09.052. [PMID: 22019467]
  • Alissa M Goble, Hao Fan, Andrej Sali, Frank M Raushel. Discovery of a cytokinin deaminase. ACS chemical biology. 2011 Oct; 6(10):1036-40. doi: 10.1021/cb200198c. [PMID: 21823622]
  • Nai-Kuei Huang, Jung-Hsin Lin, Jiun-Tsai Lin, Chia-I Lin, Eric Minwei Liu, Chun-Jung Lin, Wan-Ping Chen, Yuh-Chiang Shen, Hui-Mei Chen, Jhih-Bin Chen, Hsing-Lin Lai, Chieh-Wen Yang, Ming-Chang Chiang, Yu-Shuo Wu, Chen Chang, Jiang-Fan Chen, Jim-Min Fang, Yun-Lian Lin, Yijuang Chern. A new drug design targeting the adenosinergic system for Huntington's disease. PloS one. 2011; 6(6):e20934. doi: 10.1371/journal.pone.0020934. [PMID: 21713039]
  • Andreas Thalassitis, Dimitra J Hadjipavlou-Litina, Konstantinos E Litinas, Panagiotis Miltiadou. Synthesis of modified homo-N-nucleosides from the reactions of mesityl nitrile oxide with 9-allylpurines and their influence on lipid peroxidation and thrombin inhibition. Bioorganic & medicinal chemistry letters. 2009 Nov; 19(22):6433-6. doi: 10.1016/j.bmcl.2009.09.040. [PMID: 19811914]
  • Lucie Szücová, Lukás Spíchal, Karel Dolezal, Marek Zatloukal, Jarmila Greplová, Petr Galuszka, Vladimír Krystof, Jirí Voller, Igor Popa, Frank J Massino, Jan-Elo Jørgensen, Miroslav Strnad. Synthesis, characterization and biological activity of ring-substituted 6-benzylamino-9-tetrahydropyran-2-yl and 9-tetrahydrofuran-2-ylpurine derivatives. Bioorganic & medicinal chemistry. 2009 Mar; 17(5):1938-47. doi: 10.1016/j.bmc.2009.01.041. [PMID: 19232496]
  • Karel Dolezal, Igor Popa, Vladimír Krystof, Lukás Spíchal, Martina Fojtíková, Jan Holub, René Lenobel, Thomas Schmülling, Miroslav Strnad. Preparation and biological activity of 6-benzylaminopurine derivatives in plants and human cancer cells. Bioorganic & medicinal chemistry. 2006 Feb; 14(3):875-84. doi: 10.1016/j.bmc.2005.09.004. [PMID: 16214355]
  • Hao Wang, Lawrence J Marnett, Thomas M Harris, Carmelo J Rizzo. A novel synthesis of malondialdehyde adducts of deoxyguanosine, deoxyadenosine, and deoxycytidine. Chemical research in toxicology. 2004 Feb; 17(2):144-9. doi: 10.1021/tx034174g. [PMID: 14967001]
  • Lukas Bürkle, Anna Cedzich, Corinna Döpke, Harald Stransky, Sakiko Okumoto, Bernd Gillissen, Christina Kühn, Wolf B Frommer. Transport of cytokinins mediated by purine transporters of the PUP family expressed in phloem, hydathodes, and pollen of Arabidopsis. The Plant journal : for cell and molecular biology. 2003 Apr; 34(1):13-26. doi: 10.1046/j.1365-313x.2003.01700.x. [PMID: 12662305]
  • I Y Hwang, A A Elfarra. Detection and mechanisms of formation of S-(6-purinyl)glutathione and 6-mercaptopurine in rats given 6-chloropurine. The Journal of pharmacology and experimental therapeutics. 1993 Jan; 264(1):41-6. doi: . [PMID: 8423540]