5-Carboxy-2,7-dichlorofluorescein (BioDeep_00000686213)

   


代谢物信息卡片


2,7-DICHLORO-3,6-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9-XANTHENE]-5-CARBOXYLIC ACID

化学式: C21H10Cl2O7 (443.98035699999997)
中文名称: 2,7-二氯-3,6-二羟基-3-氧代-3H-螺[异苯并呋喃-1,9-氧杂蒽]-5-羧酸, 5-(6)-CDCF [5(6)-羧基-2,7-二氯荧光素]
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC2=C(C=C1C(=O)O)C(=O)OC23C4=CC(=C(C=C4OC5=CC(=C(C=C35)Cl)O)O)Cl
InChI: InChI=1S/C21H10Cl2O7/c22-13-4-11-17(6-15(13)24)29-18-7-16(25)14(23)5-12(18)21(11)10-2-1-8(19(26)27)3-9(10)20(28)30-21/h1-7,24-25H,(H,26,27)

描述信息

D004396 - Coloring Agents > D005456 - Fluorescent Dyes > D005452 - Fluoresceins

同义名列表

3 个代谢物同义名

2,7-DICHLORO-3,6-DIHYDROXY-3-OXO-3H-SPIRO[ISOBENZOFURAN-1,9-XANTHENE]-5-CARBOXYLIC ACID; 5(6)-carboxy-2 7-dichlorofluorescein; 5-Carboxy-2,7-dichlorofluorescein



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Delon W Barfuss, John T Buchanan, Lucy Joshee, Elizabeth H Pittman, Nigel D'Souza, Kayla E Matta, Ryan T Brownlee, Christy C Bridges. Hepatic processing of mercuric ions facilitates delivery to renal proximal tubules. Toxicology letters. 2022 Apr; 359(?):1-9. doi: 10.1016/j.toxlet.2022.01.009. [PMID: 35066093]
  • Mónika Szabó, Zsuzsa Veres, Attila Bátai-Konczos, Orsolya Kékesi, Emese Kis, Kitti Szabó, Katalin Jemnitz. Statins alter the hepatobiliary transport of unconjugated and conjugated bilirubin in sandwich-cultured rat hepatocytes. Toxicology in vitro : an international journal published in association with BIBRA. 2014 Sep; 28(6):1136-43. doi: 10.1016/j.tiv.2014.05.016. [PMID: 24909372]
  • Katharine Howe, G Gordon Gibson, Tanya Coleman, Nick Plant. In silico and in vitro modeling of hepatocyte drug transport processes: importance of ABCC2 expression levels in the disposition of carboxydichlorofluroscein. Drug metabolism and disposition: the biological fate of chemicals. 2009 Feb; 37(2):391-9. doi: 10.1124/dmd.108.022921. [PMID: 19022944]
  • J McLaurin, A Chakrabartty. Characterization of the interactions of Alzheimer beta-amyloid peptides with phospholipid membranes. European journal of biochemistry. 1997 Apr; 245(2):355-63. doi: 10.1111/j.1432-1033.1997.t01-2-00355.x. [PMID: 9151964]
  • T Satoh, N Sakai, Y Enokido, Y Uchiyama, H Hatanaka. Survival factor-insensitive generation of reactive oxygen species induced by serum deprivation in neuronal cells. Brain research. 1996 Sep; 733(1):9-14. doi: 10.1016/0006-8993(96)00527-6. [PMID: 8891242]
  • D Cao, L A Boxer, H R Petty. Deposition of reactive oxygen metabolites onto and within living tumor cells during neutrophil-mediated antibody-dependent cellular cytotoxicity. Journal of cellular physiology. 1993 Aug; 156(2):428-36. doi: 10.1002/jcp.1041560227. [PMID: 8344997]
  • A R Kendall. Cost containment: why unnecessary urine cultures?. The Journal of urology. 1979 May; 121(5):691. doi: 10.1016/s0022-5347(17)56955-4. [PMID: 439280]