METHENAMINE MANDELATE (BioDeep_00000685650)
代谢物信息卡片
化学式: C14H20N4O3 (292.1535)
中文名称: 扁桃酸乌洛托品
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1N2CN3CN1CN(C2)C3.C1=CC=C(C=C1)C(C(=O)O)O
InChI: InChI=1S/C8H8O3.C6H12N4/c9-7(8(10)11)6-4-2-1-3-5-6
描述信息
D000890 - Anti-Infective Agents > D000892 - Anti-Infective Agents, Urinary > D008333 - Mandelic Acids
C254 - Anti-Infective Agent > C255 - Urinary Anti-Infective Agent
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents
同义名列表
1 个代谢物同义名
数据库引用编号
6 个数据库交叉引用编号
- KEGGdrug: D00856
- PubChem: 11478
- ChEMBL: CHEMBL3833312
- CAS: 19442-87-6
- CAS: 6754-75-2
- CAS: 587-23-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- Linhua Zhang, Wenbo Hao, Lv Xu, Yongfeng Gao, Xusheng Wang, Dunwan Zhu, Zhuo Chen, Xudong Zhang, Hongbo Chen, Lin Mei. A pH-sensitive methenamine mandelate-loaded nanoparticle induces DNA damage and apoptosis of cancer cells.
Acta biomaterialia.
2017 10; 62(?):246-256. doi:
10.1016/j.actbio.2017.08.019. [PMID: 28822844] - J G Strom, H W Jun. Effect of urine pH and ascorbic acid on the rate of conversion of methenamine to formaldehyde.
Biopharmaceutics & drug disposition.
1993 Jan; 14(1):61-9. doi:
10.1002/bdd.2510140106. [PMID: 8427945] - A Jeantet, A Thea, U Ferrando, M Gaido, M Rotunno, P F Martini, A Vercellone. Infectious nephrolithiasis: results of treatment with methenamine mandelate.
Contributions to nephrology.
1987; 58(?):233-5. doi:
10.1159/000414526. [PMID: 3691135] - C G Kevorkian, J L Merritt, D M Ilstrup. Methenamine mandelate with acidification: an effective urinary antiseptic in patients with neurogenic bladder.
Mayo Clinic proceedings.
1984 Aug; 59(8):523-9. doi:
10.1016/s0025-6196(12)61489-x. [PMID: 6379319] - J K Devenport, J R Swenson, G E Dukes, P K Sonsalla. Formaldehyde generation from methenamine salts in spinal cord injury.
Archives of physical medicine and rehabilitation.
1984 May; 65(5):257-9. doi:
NULL. [PMID: 6712452] - R Kwieciński, J Jaworska-Wieczorek. [Evaluation of various urine-acidifying agents].
Wiadomosci lekarskie (Warsaw, Poland : 1960).
1983 Nov; 36(22):1851-4. doi:
NULL. [PMID: 6675290] - S Lamid. Ascorbic acid and methenamine mandelate on the urinary pH of spinal cord injury patients.
The Journal of urology.
1983 Apr; 129(4):845-6. doi:
10.1016/s0022-5347(17)52396-4. [PMID: 6842722] - D S Liang, J Ballou. Long term catheter care with infected urine.
Rhode Island medical journal.
1981 Mar; 64(3):153-5. doi:
NULL. [PMID: 6939057] - D Greenwood, R C Slack. The antibacterial activity of hexamine (methenamine), hexamine hippurate and hexamine mandelate.
Infection.
1981; 9(5):223-7. doi:
10.1007/bf01640720. [PMID: 7028634] - R A Roesel, M E Coryell, P R Blankenship, T G Thevaos, W K Hall. Interference by methenamine mandelate in screening for organic and amino acid disorders.
Clinica chimica acta; international journal of clinical chemistry.
1980 Jan; 100(1):55-8. doi:
10.1016/0009-8981(80)90185-0. [PMID: 7351078] - A ULLMAN. METHENAMINE MANDELATE (MANDELAMINE) IN URINARY TRACT INFECTIONS.
Medical times.
1964 Oct; 92(?):991-6. doi:
NULL. [PMID: 14200475]
