Tenofovir alafenamide (BioDeep_00000683642)
代谢物信息卡片
propan-2-yl (2S)-2-[[[(2R)-1-(6-aminopurin-9-yl)propan-2-yl]oxymethyl-phenoxyphosphoryl]amino]propanoate
化学式: C21H29N6O5P (476.1937)
中文名称: 替诺福韦艾拉酚胺, 磷丙替诺福韦, GS7340中间体
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3
InChI: InChI=1S/C21H29N6O5P/c1-14(2)31-21(28)16(4)26-33(29,32-17-8-6-5-7-9-17)13-30-15(3)10-27-12-25-18-19(22)23-11-24-20(18)27/h5-9,11-12,14-16H,10,13H2,1-4H3,(H,26,29)(H2,22,23,24)
描述信息
J - Antiinfectives for systemic use > J05 - Antivirals for systemic use > J05A - Direct acting antivirals > J05AF - Nucleoside and nucleotide reverse transcriptase inhibitors
C471 - Enzyme Inhibitor > C1589 - Reverse Transcriptase Inhibitor > C97452 - Nucleoside Reverse Transcriptase Inhibitor
C254 - Anti-Infective Agent > C281 - Antiviral Agent
同义名列表
数据库引用编号
10 个数据库交叉引用编号
- ChEBI: CHEBI:90926
- KEGGdrug: D10428
- PubChem: 9574768
- PubChem: 72370618
- DrugBank: DB09299
- ChEMBL: CHEMBL2107825
- ChEMBL: CHEMBL4303549
- CAS: 379270-37-8
- CAS: 383365-04-6
- CAS: 379270-36-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Dathan M Byonanebye, Mark N Polizzotto, Fernando Maltez, Andri Rauch, Katharina Grabmeier-Pfistershammer, Ferdinand Wit, Stéphane De Wit, Antonella Castagna, Antonella d'Arminio Monforte, Cristina Mussini, Jan-Christian Wasmuth, Eric Fontas, Irene Abela, Mario Sarcletti, Loveleen Bansi-Matharu, Nadine Jaschinski, Lars Peters, Sean R Hosein, Vani Vannappagari, Cal Cohen, Emiliano Bissio, Amanda Mocroft, Matthew Law, Lene Ryom, Kathy Petoumenos. Associations between change in BMI and the risk of hypertension and dyslipidaemia in people receiving integrase strand-transfer inhibitors, tenofovir alafenamide, or both compared with other contemporary antiretroviral regimens: a multicentre, prospective observational study from the RESPOND consortium cohorts.
The lancet. HIV.
2024 May; 11(5):e321-e332. doi:
10.1016/s2352-3018(23)00328-4. [PMID: 38621392] - Jen-Yu Hsu, Hsin-Yun Sun, Ling-Ya Chen, Sui-Yuan Chang, Yu-Chung Chuang, Yu-Shan Huang, Yi-Ching Su, Wen-Chun Liu, Chien-Ching Hung. Weight and metabolic changes among virally suppressed people with HIV who switched to co-formulated bictegravir/emtricitabine/tenofovir alafenamide.
Journal of global antimicrobial resistance.
2024 Mar; 36(?):426-435. doi:
10.1016/j.jgar.2023.10.012. [PMID: 37923129] - Lin Gan, Xiaoxin Xie, Yanhua Fu, Yebing Song, Chunli Song, Tingting Ren, Hai Long. Efficacy and safety of bictegravir/emtricitabine/tenofovir alafenamide fumarate for adult patients with human immunodeficiency virus-1 in China: a retrospective real-world cohort study.
Expert review of anti-infective therapy.
2023 Dec; ?(?):1-7. doi:
10.1080/14787210.2023.2292544. [PMID: 38058002] - Yinghua Wei, Jin Li, Ruhong Xu, Li Wen, Yiming Deng, Lixia He, Huijun Zhong, Yanhao Wang. Efficacy and safety profiles of dolutegravir plus lamivudine vs. bictegravir/emtricitabine/tenofovir alafenamide in therapy-naïve adults with HIV-1.
Chinese medical journal.
2023 Nov; ?(?):. doi:
10.1097/cm9.0000000000002907. [PMID: 37914678] - Sandra Rotea-Salvo, Víctor Giménez-Arufe, Alejandro Martínez-Pradeda, Carla Fernández-Oliveira, Álvaro Mena-de-Cea, Luis Margusino-Framiñán, Isabel Martín-Herranz, Purificación Cid-Silva. Lipid profile changes associated with antiretroviral therapies in a real-world cohort.
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria.
2023 Sep; 47(5):T210-T217. doi:
10.1016/j.farma.2023.07.005. [PMID: 37673703] - Sandra Rotea-Salvo, Víctor Giménez-Arufe, Alejandro Martínez-Pradeda, Carla Fernández-Oliveira, Álvaro Mena-de-Cea, Luis Margusino-Framiñán, Isabel Martín-Herranz, Purificación Cid-Silva. Lipid profile changes associated with antiretroviral therapies in a real-world cohort.
Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria.
2023 Jun; ?(?):. doi:
10.1016/j.farma.2023.04.007. [PMID: 37349200] - Alessandro Lazzaro, Diana Bianchini, Elio Gentilini Cacciola, Ivano Mezzaroma, Mario Falciano, Carolina Andreoni, Caterina Fimiani, Letizia Santinelli, Luca Maddaloni, Ginevra Bugani, Giancarlo Ceccarelli, Claudio Maria Mastroianni, Gabriella d'Ettorre. Immune Reconstitution and Safe Metabolic Profile after the Switch to Bictegravir/Emtricitabine/Tenofovir Alafenamide Fumarate among Virologically Controlled PLWH: A 96 Week Update from the BICTEL Cohort.
Viruses.
2023 05; 15(6):. doi:
10.3390/v15061222. [PMID: 37376522] - Ryoko Sekiya, Takashi Muramatsu, Akito Ichiki, Yushi Chikasawa, Masato Bingo, Mihoko Yotsumoto, Takeshi Hagiwara, Kagehiro Amano, Ei Kinai. Young age is a key determinant of body weight gain after switching from tenofovir disoproxil fumarate to tenofovir alafenamide in Japanese people living with HIV.
Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy.
2023 Feb; 29(2):171-178. doi:
10.1016/j.jiac.2022.10.014. [PMID: 37589078] - Nicola Squillace, Elena Ricci, Paolo Maggi, Lucia Taramasso, Barbara Menzaghi, Giuseppe Vittorio De Socio, Stefania Piconi, Benedetto Maurizio Celesia, Giancarlo Orofino, Eleonora Sarchi, Giovanni Francesco Pellicanò, Filomena Simeone, Laura Valsecchi, Alessandra Bandera, Giovanni Cenderello, Letizia Attala, Goffredo Angioni, Katia Falasca, Antonio Cascio, Olivia Bargiacchi, Antonio Di Biagio, Paolo Bonfanti. Real-life safety of Emtricitabine/Tenofovir Alafenamide/Bictegravir.
PloS one.
2023; 18(8):e0289132. doi:
10.1371/journal.pone.0289132. [PMID: 37556481] - Franco Maggiolo, Giuliano Rizzardini, Jean-Michel Molina, Federico Pulido, Stephane De Wit, Linos Vandekerckhove, Juan Berenguer, Michelle L D'Antoni, Christiana Blair, Susan K Chuck, David Piontkowsky, Hal Martin, Richard Haubrich, Ian R McNicholl, Joel Gallant. Bictegravir/emtricitabine/tenofovir alafenamide in older individuals with HIV: Results of a 96-week, phase 3b, open-label, switch trial in virologically suppressed people ≥65 years of age.
HIV medicine.
2023 01; 24(1):27-36. doi:
10.1111/hiv.13319. [PMID: 35527425] - Liqin Sun, Yun He, Liumei Xu, Fang Zhao, Yang Zhou, Lukun Zhang, Qiaoli Peng, Haitao Zhang, Qiuyue Zhang, Tingzhi Cao, Ying Song, Siyuan Wang, Man Rao, Xinyun Jia, Xiaoning Liu, Jing Zhou, Bin Ju, Hui Wang, Jiaye Liu. Higher Risk of Dyslipidemia With Coformulated Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide than Efavirenz, Lamivudine, and Tenofovir Disoproxil Fumarate Among Antiretroviral-Naive People Living With HIV in China.
Journal of acquired immune deficiency syndromes (1999).
2022 10; 91(S1):S8-S15. doi:
10.1097/qai.0000000000003040. [PMID: 36094509] - William Liu, Sarah Yu, Bingfang Yan. Effect of alcohol exposure on the efficacy and safety of tenofovir alafenamide fumarate, a major medicine against human immunodeficiency virus.
Biochemical pharmacology.
2022 10; 204(?):115224. doi:
10.1016/j.bcp.2022.115224. [PMID: 36007574] - Olayemi Osiyemi, Stéphane De Wit, Faïza Ajana, Fiona Bisshop, Joaquín Portilla, Jean Pierre Routy, Christoph Wyen, Mounir Ait-Khaled, Peter Leone, Keith A Pappa, Ruolan Wang, Jonathan Wright, Nisha George, Brian Wynne, Michael Aboud, Jean van Wyk, Kimberly Y Smith. Efficacy and Safety of Switching to Dolutegravir/Lamivudine Versus Continuing a Tenofovir Alafenamide-Based 3- or 4-Drug Regimen for Maintenance of Virologic Suppression in Adults Living With Human Immunodeficiency Virus Type 1: Results Through Week 144 From the Phase 3, Noninferiority TANGO Randomized Trial.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2022 09; 75(6):975-986. doi:
10.1093/cid/ciac036. [PMID: 35079789] - Tahrima Kayes, Harry Crane, Allison Symonds, Julie Dumond, Mackenzie Cottrell, Julia Di Girolamo, Sicha Manandhar, Tien Huey Lim, Edward Gane, Angela Kashuba, Miriam T Levy. Plasma and breast milk pharmacokinetics of tenofovir alafenamide in mothers with chronic hepatitis B infection.
Alimentary pharmacology & therapeutics.
2022 Aug; 56(3):510-518. doi:
10.1111/apt.17040. [PMID: 35599363] - Miriam T Levy, Angela Kashuba, Edward Gane. Plasma and breast milk pharmacokinetics of tenofovir alafenamide of mothers with chronic hepatitis B infection-Authors' reply.
Alimentary pharmacology & therapeutics.
2022 Aug; 56(3):548-549. doi:
10.1111/apt.17102. [PMID: 35804469] - Mei-Hsuan Lee. Plasma and breast milk pharmacokinetics of tenofovir alafenamide in mothers with chronic hepatitis B infection.
Alimentary pharmacology & therapeutics.
2022 Aug; 56(3):546-547. doi:
10.1111/apt.17079. [PMID: 35804473] - Jihye Lim, Won-Mook Choi, Ju Hyun Shim, Danbi Lee, Kang Mo Kim, Young-Suk Lim, Han Chu Lee, Jonggi Choi. Efficacy and safety of tenofovir alafenamide versus tenofovir disoproxil fumarate in treatment-naïve chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver.
2022 07; 42(7):1517-1527. doi:
10.1111/liv.15261. [PMID: 35343041] - Eiichi Ogawa, Makoto Nakamuta, Toshimasa Koyanagi, Aritsune Ooho, Norihiro Furusyo, Eiji Kajiwara, Kazufumi Dohmen, Akira Kawano, Takeaki Satoh, Kazuhiro Takahashi, Koichi Azuma, Nobuyuki Yamashita, Naoki Yamashita, Rie Sugimoto, Hiromasa Amagase, Masami Kuniyoshi, Yasunori Ichiki, Chie Morita, Masaki Kato, Shinji Shimoda, Hideyuki Nomura, Jun Hayashi. Switching to tenofovir alafenamide for nucleos(t)ide analogue-experienced patients with chronic hepatitis B: Week 144 results from a real-world, multicentre cohort study.
Alimentary pharmacology & therapeutics.
2022 Jun; ?(?):. doi:
10.1111/apt.17107. [PMID: 35735794] - Kai Juhani Kauppinen, Inka Aho, Jussi Sutinen. Switching from tenofovir alafenamide to tenofovir disoproxil fumarate improves lipid profile and protects from weight gain.
AIDS (London, England).
2022 Jun; ?(?):. doi:
10.1097/qad.0000000000003245. [PMID: 35727143] - Jennifer Lagoutte-Renosi, Mylène Flammang, Didier Ducloux, Jamal Bamoulid, Pierre-Yves Royer, Quentin Lepiller, Anne-Laure Clairet, Siamak Davani, Patrice Muret. Bictegravir/emtricitabine/tenofovir alafenamide combination in the management of kidney transplant patients with HIV receiving immunosuppressants.
Journal of chemotherapy (Florence, Italy).
2022 May; 34(3):199-202. doi:
10.1080/1120009x.2021.1940436. [PMID: 34180378] - Chan-Young Jung, Hyung Woo Kim, Sang Hoon Ahn, Seung Up Kim, Beom Seok Kim. Higher risk of kidney function decline with entecavir than tenofovir alafenamide in patients with chronic hepatitis B.
Liver international : official journal of the International Association for the Study of the Liver.
2022 05; 42(5):1017-1026. doi:
10.1111/liv.15208. [PMID: 35220649] - E Sinakos, P Panas, N Fragkou, N Antoniadis, G Katsanos, E Tsakni, T Oikonomou, A Notopoulos, G Tsoulfas, I Goulis, E Akriviadis. Tenofovir alafenamide prophylaxis post-liver transplantation: a real-world study in patients with chronic kidney disease.
Acta gastro-enterologica Belgica.
2022 Apr; 85(2):331-337. doi:
10.51821/85.2.9577. [PMID: 35709777] - Eiichi Ogawa, Makoto Nakamuta, Toshimasa Koyanagi, Aritsune Ooho, Norihiro Furusyo, Eiji Kajiwara, Kazufumi Dohmen, Akira Kawano, Takeaki Satoh, Kazuhiro Takahashi, Koichi Azuma, Nobuyuki Yamashita, Naoki Yamashita, Rie Sugimoto, Hiromasa Amagase, Masami Kuniyoshi, Yasunori Ichiki, Chie Morita, Masaki Kato, Shinji Shimoda, Hideyuki Nomura, Jun Hayashi. Sequential HBV treatment with tenofovir alafenamide for patients with chronic hepatitis B: week 96 results from a real-world, multicenter cohort study.
Hepatology international.
2022 Apr; 16(2):282-293. doi:
10.1007/s12072-021-10295-3. [PMID: 35075593] - Joonho Jeong, Jung Woo Shin, Seok Won Jung, Eun Ji Park, Neung Hwa Park. Tenofovir alafenamide treatment may not worsen the lipid profile of chronic hepatitis B patients: A propensity score-matched analysis.
Clinical and molecular hepatology.
2022 04; 28(2):254-264. doi:
10.3350/cmh.2021.0314. [PMID: 34959261] - Derin Sevenler, Xin Niu, Sandy Dossantos, Mehmet Toner, Tim R Cressey, Rebecca D Sandlin, Paul K Drain. Point-of-care semi-quantitative test for adherence to tenofovir alafenamide or tenofovir disoproxil fumarate.
The Journal of antimicrobial chemotherapy.
2022 03; 77(4):996-999. doi:
10.1093/jac/dkab487. [PMID: 35038336] - Xiaoping Qian, Qi Chen, Yunhui Chen, Shiliang Ji, Ying Wang, Ye Sun, Huixin Qi, Kan Zhong, Jinfang Jiang, Xin Chen, Lifeng Huang, Yong Yang. A simple and fast LC-MS/MS method for the simultaneous determination of tenofovir alafenamide and tenofovir in human plasma.
Biomedical chromatography : BMC.
2022 Mar; 36(3):e5273. doi:
10.1002/bmc.5273. [PMID: 34725843] - Wenting Peng, Huimin Gu, Chuan Jiang, Jinqing Liu, Jian Zhang, Lei Fu. Comparison of tenofovir alafenamide and entecavir for hepatitis B virus-related acute-on-chronic liver failure.
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2022 Feb; 47(2):194-201. doi:
10.11817/j.issn.1672-7347.2022.210578. [PMID: 35545409] - A Geragotellis, S Patel, M Sonderup, N Wearne, Z Barday, L Sanglay, V Naicker, C W Spearman. Tenofovir alafenamide: An initial experience at Groote Schuur Hospital, Cape Town, South Africa.
South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.
2022 Feb; 112(2):13505. doi:
NULL. [PMID: 35139993] - Yoshihito Uchida, Masamitsu Nakao, Shunsuke Yamada, Shohei Tsuji, Hayato Uemura, Jun-Ichi Kouyama, Kayoko Naiki, Kayoko Sugawara, Nobuaki Nakayama, Yukinori Imai, Tomoaki Tomiya, Satoshi Mochida. Superiority of tenofovir alafenamide fumarate over entecavir for serum HBsAg level reduction in patients with chronic HBV infection: A 144-week outcome study after switching of the nucleos(t)ide analog.
PloS one.
2022; 17(2):e0262764. doi:
10.1371/journal.pone.0262764. [PMID: 35180213] - Pimsiri Sripongpun, W Ray Kim, Ajitha Mannalithara, Allison Kwong, Tami Daugherty, Aparna Goel, Paul Y Kwo. Tenofovir Alafenamide Attenuates Effects of Diabetes and Body Mass on Serum Alanine Aminotransferase Activities in Patients With Chronic Hepatitis B.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.
2022 01; 20(1):230-232. doi:
10.1016/j.cgh.2020.11.047. [PMID: 33285291] - Kazuharu Suzuki, Goki Suda, Yoshiya Yamamoto, Satoshi Abiko, Kenji Kinoshita, Shuichi Miyamoto, Ryo Sugiura, Megumi Kimura, Osamu Maehara, Ren Yamada, Takashi Kitagataya, Taku Shigesawa, Masatsugu Ohara, Naoki Kawagishi, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Kenichi Morikawa, Koji Ogawa, Naoya Sakamoto. Effect of switching from tenofovir disoproxil fumarate to tenofovir alafenamide on lipid profiles in patients with hepatitis B.
PloS one.
2022; 17(1):e0261760. doi:
10.1371/journal.pone.0261760. [PMID: 35051189] - Kensuke Abe, Taku Obara, Satomi Kamio, Asahi Kondo, Junji Imamura, Tatsuya Goto, Toshihiro Ito, Hiroshi Sato, Nobuyuki Takahashi. Renal function in Japanese HIV-1-positive patients who switch to tenofovir alafenamide fumarate after long-term tenofovir disoproxil fumarate: a single-center observational study.
AIDS research and therapy.
2021 12; 18(1):94. doi:
10.1186/s12981-021-00420-5. [PMID: 34876151] - Bo-Huang Liou, Chih-Ning Cheng, Ya-Ting Lin, Yu-Jou Lin, Yu-Chung Chuang, Kuan-Yin Lin, Wen-Chun Liu, Shu-Wen Lin, Ching-Hua Kuo, Hsin-Yun Sun, Chien-Ching Hung. Short-course daily isoniazid and rifapentine for latent tuberculosis infection in people living with HIV who received coformulated bictegravir/emtricitabine/tenofovir alafenamide.
Journal of the International AIDS Society.
2021 11; 24(11):e25844. doi:
10.1002/jia2.25844. [PMID: 34822220] - Laurence Brunet, Patrick Mallon, Jennifer S Fusco, Michael B Wohlfeiler, Girish Prajapati, Andrew Beyer, Gregory P Fusco. Switch from Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in People Living with HIV: Lipid Changes and Statin Underutilization.
Clinical drug investigation.
2021 Nov; 41(11):955-965. doi:
10.1007/s40261-021-01081-y. [PMID: 34546533] - Huan Xia, Xiao-Jie Huang, Yue Hu, Li-Ying Gao, Yue Wu, Hao Wu, Zhong-Fang Yan, Ping Ma. Switching from efavirenz to elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide reduces central nervous system symptoms in people living with HIV.
Chinese medical journal.
2021 Oct; 134(23):2850-2856. doi:
10.1097/cm9.0000000000001824. [PMID: 34653085] - Arkaitz Imaz, Juan M Tiraboschi, Jordi Niubó, Javier Martinez-Picado, Mackenzie L Cottrell, Pere Domingo, Ivan Chivite, Eugenia Negredo, Amanda Schauer, Brian Van Horne, Sandra Morenilla, Víctor Urrea, Ana Silva-Klug, Sofía Scévola, Benito Garcia, Angela D M Kashuba, Daniel Podzamczer. Dynamics of the Decay of Human Immunodeficiency Virus (HIV) RNA and Distribution of Bictegravir in the Genital Tract and Rectum in Antiretroviral-naive Adults Living With HIV-1 Treated With Bictegravir/Emtricitabine/Tenofovir Alafenamide (Spanish HIV/AIDS Research Network, PreEC/RIS 58).
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2021 10; 73(7):e1991-e1999. doi:
10.1093/cid/ciaa1416. [PMID: 32945851] - Baijun Li, Zhaozhe Liu, Xing Liu, Dongchun Liu, Mingyu Duan, Ye Gu, Qiong Liu, Qiang Ma, Yushi Wei, Yan Wang. Efficacy and safety of tenofovir disoproxil fumarate and tenofovir alafenamide fumarate in preventing HBV vertical transmission of high maternal viral load.
Hepatology international.
2021 Oct; 15(5):1103-1108. doi:
10.1007/s12072-021-10235-1. [PMID: 34312798] - Lucy Campbell, Birgit Barbini, Keith Burling, Ben Cromarty, Lisa Hamzah, Margaret Johnson, Rachael Jones, Amanda Samarawickrama, Deborah Williams, Alan Winston, Frank A Post. Safety of Tenofovir Alafenamide in People With HIV Who Experienced Proximal Renal Tubulopathy on Tenofovir Disoproxil Fumarate.
Journal of acquired immune deficiency syndromes (1999).
2021 10; 88(2):214-219. doi:
10.1097/qai.0000000000002747. [PMID: 34506361] - Pierre-Emmanuel Plum, Nathalie Maes, Anne-Sophie Sauvage, Frédéric Frippiat, Christelle Meuris, Françoise Uurlings, Marianne Lecomte, Philippe Léonard, Nicolas Paquot, Karine Fombellida, Dolores Vaira, Michel Moutschen, Gilles Darcis. Impact of switch from tenofovir disoproxil fumarate-based regimens to tenofovir alafenamide-based regimens on lipid profile, weight gain and cardiovascular risk score in people living with HIV.
BMC infectious diseases.
2021 Sep; 21(1):910. doi:
10.1186/s12879-021-06479-9. [PMID: 34488664] - Kelly A Johnson, Hideaki Okochi, David V Glidden, Monica Gandhi, Matthew Spinelli. Brief Report: No Difference in Urine Tenofovir Levels in Patients Living With HIV on Unboosted Versus Dose-Adjusted Boosted Tenofovir Alafenamide.
Journal of acquired immune deficiency syndromes (1999).
2021 09; 88(1):57-60. doi:
10.1097/qai.0000000000002727. [PMID: 33990489] - Thornthun Ueaphongsukkit, Sivaporn Gatechompol, Anchalee Avihingsanon, Jerasit Surintrspanont, Kroonpong Iampenkhae, Yingyos Avihingsanon, Suwasin Udomkarnjananun. Tenofovir alafenamide nephrotoxicity: a case report and literature review.
AIDS research and therapy.
2021 08; 18(1):53. doi:
10.1186/s12981-021-00380-w. [PMID: 34419091] - Lu Wang, Lina Wu, Xuejun Li, Ying Zhang, Jing Lai, Xiang Zhu, Chan Xie, Liang Peng. Tenofovir alafenamide fumarate therapy in subjects with positive HBV-DNA and normal levels of alanine transaminase: a study protocol for a randomised controlled trial.
BMJ open.
2021 08; 11(8):e048410. doi:
10.1136/bmjopen-2020-048410. [PMID: 34408049] - M Gutiérrez-Lorenzo, D Rubio-Calvo, J Urda-Romacho. [Effectiveness, safety, and economic impact of the bictegravir/emtricitabine/tenofovir alafenamide regimen in real clinical practice cohort of HIV-1 infected adult patients].
Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia.
2021 Aug; 34(4):315-319. doi:
10.37201/req/148.2020. [PMID: 34032111] - Mostafa Shokoohi, Meenakshi Gupta, Fred Crouzat, Graham Smith, Colin Kovacs, Jason Brunetta, Benny Chang, David Knox, Megan Acsai, Barry Merkley, Kevin Giolma, David Fletcher, Mona Loutfy. Changes in renal and metabolic indices after switching from tenofovir disoproxil fumarate- to tenofovir alafenamide-containing ART among individuals with HIV in Canada: A retrospective study.
International journal of STD & AIDS.
2021 08; 32(9):861-871. doi:
10.1177/0956462421999931. [PMID: 33890817] - Hidenori Toyoda, Jennifer Leong, Charles Landis, Masanori Atsukawa, Tsunamasa Watanabe, Daniel Q Huang, Joanne Liu, Sabrina Xin Zi Quek, Toru Ishikawa, Taeang Arai, Keisuke Yokohama, Makoto Chuma, Koichi Takaguchi, Haruki Uojima, Tomonori Senoo, Hansen Dang, Mayumi Maeda, Joseph Hoang, Richard H Le, Satoshi Yasuda, Khin N Thin, Sally Tran, Nicholas Chien, Linda Henry, Akira Asai, Shinya Fukunishi, Ramsey Cheung, Seng Gee Lim, Huy N Trinh, Mindie H Nguyen. Treatment and Renal Outcomes Up to 96 Weeks After Tenofovir Alafenamide Switch From Tenofovir Disoproxil Fumarate in Routine Practice.
Hepatology (Baltimore, Md.).
2021 08; 74(2):656-666. doi:
10.1002/hep.31793. [PMID: 33706421] - Paul E Sax, Jürgen K Rockstroh, Anne F Luetkemeyer, Yazdan Yazdanpanah, Douglas Ward, Benoit Trottier, Armin Rieger, Hui Liu, Rima Acosta, Sean E Collins, Diana M Brainard, Hal Martin. Switching to Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Virologically Suppressed Adults With Human Immunodeficiency Virus.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
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HIV medicine.
2021 07; 22(6):457-466. doi:
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BMC infectious diseases.
2021 Jun; 21(1):567. doi:
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The AAPS journal.
2021 06; 23(4):82. doi:
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Journal of viral hepatitis.
2021 06; 28(6):942-950. doi:
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Liver international : official journal of the International Association for the Study of the Liver.
2021 06; 41 Suppl 1(?):9-14. doi:
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Annals of internal medicine.
2021 06; 174(6):758-767. doi:
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The lancet. HIV.
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AIDS research and human retroviruses.
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AIDS research and therapy.
2021 05; 18(1):30. doi:
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Antimicrobial agents and chemotherapy.
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Journal of acquired immune deficiency syndromes (1999).
2021 04; 86(4):473-481. doi:
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Journal of viral hepatitis.
2021 04; 28(4):592-600. doi:
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Antimicrobial agents and chemotherapy.
2021 03; 65(4):. doi:
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2021 Mar; 32(2):592-594. doi:
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The Journal of antimicrobial chemotherapy.
2021 02; 76(3):692-698. doi:
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HIV medicine.
2021 02; 22(2):140-145. doi:
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Drug design, development and therapy.
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Journal of managed care & specialty pharmacy.
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Clinical pharmacology and therapeutics.
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The lancet. HIV.
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HIV medicine.
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AIDS research and human retroviruses.
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Antimicrobial agents and chemotherapy.
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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
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BMC nephrology.
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The Journal of infectious diseases.
2020 07; 222(4):637-645. doi:
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Antimicrobial agents and chemotherapy.
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BMC infectious diseases.
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Liver international : official journal of the International Association for the Study of the Liver.
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HIV medicine.
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AIDS (London, England).
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International journal of pharmaceutics.
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Biomedica : revista del Instituto Nacional de Salud.
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The lancet. Gastroenterology & hepatology.
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AIDS (London, England).
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International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
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Sexual health.
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Analytical biochemistry.
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HIV medicine.
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Journal of medical virology.
2020 03; 92(3):329-338. doi:
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International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.
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Antimicrobial agents and chemotherapy.
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Current clinical pharmacology.
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Drug design, development and therapy.
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AIDS research and therapy.
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