SMCC (BioDeep_00000682469)
代谢物信息卡片
化学式: C16H18N2O6 (334.1164808)
中文名称: 4-(N-马来酰亚胺甲基)环己烷羧酸 -N-琥珀酰亚胺酯, 反式-4-(马来酰亚胺甲基)环己烷羧酸-NHS
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)ON3C(=O)CCC3=O
InChI: InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Li Li, Chanrui Wang, Yijue Wu, Lihou Dong, Fang Chen, Kelly Dong, Haifeng Song. Simple and Rapid LC-MS/MS Methods for Quantifying Catabolites of Antibody-Drug Conjugates with SMCC Linker.
Journal of chromatographic science.
2021 Jun; 59(7):642-649. doi:
10.1093/chromsci/bmaa122. [PMID: 33420505] - Lei Ye, Na-Li Huang, Xue-Ling Ma, Marion Schneider, Xin-Jiu Huang, Wei-Dong Du. Establishment of N-succinimidyl 4-(maleimidomethyl) cyclohexanecarboxylate (SMCC) modified biochip enabling concurrent detection of serum infectious antibodies in neuroborreliosis.
Biosensors & bioelectronics.
2016 Apr; 78(?):404-410. doi:
10.1016/j.bios.2015.11.050. [PMID: 26655180] - Shannen Lau, Bim Graham, Nga Cao, Ben J Boyd, Colin W Pouton, Paul J White. Enhanced extravasation, stability and in vivo cardiac gene silencing via in situ siRNA-albumin conjugation.
Molecular pharmaceutics.
2012 Jan; 9(1):71-80. doi:
10.1021/mp2002522. [PMID: 22141328] - Nathan Fishkin, Erin K Maloney, Ravi V J Chari, Rajeeva Singh. A novel pathway for maytansinoid release from thioether linked antibody-drug conjugates (ADCs) under oxidative conditions.
Chemical communications (Cambridge, England).
2011 Oct; 47(38):10752-4. doi:
10.1039/c1cc14164c. [PMID: 21874179] - Yelena V Kovtun, Charlene A Audette, Michele F Mayo, Gregory E Jones, Heather Doherty, Erin K Maloney, Hans K Erickson, Xiuxia Sun, Sharon Wilhelm, Olga Ab, Katharine C Lai, Wayne C Widdison, Brenda Kellogg, Holly Johnson, Jan Pinkas, Robert J Lutz, Rajeeva Singh, Victor S Goldmacher, Ravi V J Chari. Antibody-maytansinoid conjugates designed to bypass multidrug resistance.
Cancer research.
2010 Mar; 70(6):2528-37. doi:
10.1158/0008-5472.can-09-3546. [PMID: 20197459] - Chunhua Shi, Matthew F Paige, Jason Maley, Michèle C Loewen. In vitro characterization of ligand-induced oligomerization of the S. cerevisiae G-protein coupled receptor, Ste2p.
Biochimica et biophysica acta.
2009 Jan; 1790(1):1-7. doi:
10.1016/j.bbagen.2008.10.003. [PMID: 18996443] - C D Karapitta, T G Sotiroudis, A Papadimitriou, A Xenakis. Homogeneous enzyme immunoassay for triiodothyronine in serum.
Clinical chemistry.
2001 Mar; 47(3):569-74. doi:
10.1093/clinchem/47.3.569. [PMID: 11238313] - W Jarmuszkiewicz, A M Wagner, M J Wagner, L Hryniewiecka. Immunological identification of the alternative oxidase of Acanthamoeba castellanii mitochondria.
FEBS letters.
1997 Jul; 411(1):110-4. doi:
10.1016/s0014-5793(97)00676-5. [PMID: 9247153] - M D Phaneuf, S A Berceli, M J Bide, W C Quist, F W LoGerfo. Covalent linkage of recombinant hirudin to poly(ethylene terephthalate) (Dacron): creation of a novel antithrombin surface.
Biomaterials.
1997 May; 18(10):755-65. doi:
10.1016/s0142-9612(96)00193-7. [PMID: 9158859] - M Kurobe, Y Takei, T Fukatsu, A Kato, K Hayashi. Peroxidase-linked anti-basic fibroblast growth factor monoclonal antibody Fab' conjugates: application for two-site enzyme immunoassay and immunohistochemical detection.
Bioconjugate chemistry.
1993 Mar; 4(2):134-8. doi:
10.1021/bc00020a005. [PMID: 7873645] - E Weiss, M H Van Regenmortel. Use of rabbit Fab'-peroxidase conjugates prepared by the maleimide method for detecting plant viruses by ELISA.
Journal of virological methods.
1989 Apr; 24(1-2):11-25. doi:
10.1016/0166-0934(89)90003-7. [PMID: 2668313]