Buthiazide (BioDeep_00000681402)
代谢物信息卡片
化学式: C11H16ClN3O4S2 (353.0270726)
中文名称: 布噻嗪
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(C)CC1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl
InChI: InChI=1S/C11H16ClN3O4S2/c1-6(2)3-11-14-8-4-7(12)9(20(13,16)17)5-10(8)21(18,19)15-11/h4-6,11,14-15H,3H2,1-2H3,(H2,13,16,17)
描述信息
C78275 - Agent Affecting Blood or Body Fluid > C448 - Diuretic > C49185 - Thiazide Diuretic
D002317 - Cardiovascular Agents > D000959 - Antihypertensive Agents
D002317 - Cardiovascular Agents > D045283 - Natriuretic Agents
D045283 - Natriuretic Agents > D004232 - Diuretics
同义名列表
1 个代谢物同义名
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:135492
- KEGGdrug: D03189
- PubChem: 16274
- ChEMBL: CHEMBL2104197
- CAS: 2043-38-1
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Han Hui Caline Koh-Tan, Delyth Graham, Carlene A Hamilton, Gavin Nicoll, Laura Fields, Martin W McBride, Barbara Young, Anna F Dominiczak. Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure.
Journal of hypertension.
2009 Aug; 27(8):1575-84. doi:
10.1097/hjh.0b013e32832cc5a1
. [PMID: 19531963] - Jochen Beyer, Anabelle Bierl, Frank T Peters, Hans H Maurer. Screening procedure for detection of diuretics and uricosurics and/or their metabolites in human urine using gas chromatography-mass spectrometry after extractive methylation.
Therapeutic drug monitoring.
2005 Aug; 27(4):509-20. doi:
10.1097/01.ftd.0000160719.96445.91
. [PMID: 16044110] - M Suzuki, T Aso, T Sato, M Michimata, I Kazama, H Saiki, R Hatano, Y Ejima, N Miyama, A Sato, M Matsubara. A case of gain-of-function mutation in calcium-sensing receptor: supplemental hydration is required for renal protection.
Clinical nephrology.
2005 Jun; 63(6):481-6. doi:
10.5414/cnp63481
. [PMID: 15960151] - A V Nedostup, V I Fedorova, A Iu Linevich, T G Pukhal'skaia, G G Toropina, V S Kudrin, P M Klodt. [Anxiodepressive and neuromediatory disorders in hypertensive patients. Effects of cypramil therapy].
Terapevticheskii arkhiv.
2005; 77(11):55-62. doi:
NULL
. [PMID: 16404864] - D Fliser, M Schröter, M Neubeck, E Ritz. Coadministration of thiazides increases the efficacy of loop diuretics even in patients with advanced renal failure.
Kidney international.
1994 Aug; 46(2):482-8. doi:
10.1038/ki.1994.298
. [PMID: 7967362] - S Morabito, M Fabiano, M Puliti, R Palumbo, R Marinelli, B M Simonetti, A Pierucci. [Potassium canrenoate and the combination of potassium canrenoate-butizide in the therapy of light to moderate arterial hypertension].
La Clinica terapeutica.
1992 Jul; 141(7):23-8. doi:
NULL
. [PMID: 1505173] - R Brunkhorst, E Wrenger, K Kühn, F W Schmidt, K Koch. [Effect of captopril therapy on sodium and water excretion in patients with liver cirrhosis and ascites].
Klinische Wochenschrift.
1989 Aug; 67(15):774-83. doi:
10.1007/bf01745350
. [PMID: 2671477] - H Mauersberger, B Rangoonwala, E Ehrlich. [Comparative study of 2 diuretic-containing combination preparations in patients with edematous heart failure].
Wiener medizinische Wochenschrift (1946).
1985 Apr; 135(8):205-13. doi:
NULL
. [PMID: 4013351] - A Salama, C Mueller-Eckhardt, K Kissel, H Pralle, W Seeger. Ex vivo antigen preparation for the serological detection of drug-dependent antibodies in immune haemolytic anaemias.
British journal of haematology.
1984 Nov; 58(3):525-31. doi:
10.1111/j.1365-2141.1984.tb04000.x
. [PMID: 6208933] - F Matzkies, B Webs. [Electrolyte excretion following administration of various diuretics in healthy females].
Fortschritte der Medizin.
1984 Feb; 102(6):133-7. doi:
NULL
. [PMID: 6706271]