Decamethylcyclopentasiloxane (BioDeep_00000680180)

   


代谢物信息卡片


Decamethylcyclopentasiloxane

化学式: C10H30O5Si5 (370.093953)
中文名称: 环五聚二甲基硅氧烷
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C[Si]1(O[Si](O[Si](O[Si](O[Si](O1)(C)C)(C)C)(C)C)(C)C)C
InChI: InChI=1S/C10H30O5Si5/c1-16(2)11-17(3,4)13-19(7,8)15-20(9,10)14-18(5,6)12-16/h1-10H3

描述信息

D001697 - Biomedical and Dental Materials

同义名列表

2 个代谢物同义名

Decamethylcyclopentasiloxane; Cyclomethicone 5



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Lifang Zhang, Ruifen Jiang, Wanbin Li, Derek C G Muir, Eddy Y Zeng. Development of a solid-phase microextraction method for fast analysis of cyclic volatile methylsiloxanes in water. Chemosphere. 2020 Jul; 250(?):126304. doi: 10.1016/j.chemosphere.2020.126304. [PMID: 32120150]
  • Dominika Krenczkowska, Krystyna Mojsiewicz-Pieńkowska, Bartosz Wielgomas, Krzysztof Cal, Rafał Bartoszewski, Sylwia Bartoszewska, Zbigniew Jankowski. The consequences of overcoming the human skin barrier by siloxanes (silicones) Part 1. Penetration and permeation depth study of cyclic methyl siloxanes. Chemosphere. 2019 Sep; 231(?):607-623. doi: 10.1016/j.chemosphere.2018.09.154. [PMID: 30292575]
  • Jeanne Y Domoradzki, Jacob M Sushynski, Lisa M Thackery, Timothy A Springer, Timothy L Ross, Kent B Woodburn, Jeremy A Durham, Debra A McNett. Metabolism of 14C-octamethylcyclotetrasiloxane ([14C]D4) or 14C-decamethylcyclopentasiloxane ([14C]D5) orally gavaged in rainbow trout (Oncorhynchus mykiss). Toxicology letters. 2017 Oct; 279 Suppl 1(?):115-124. doi: 10.1016/j.toxlet.2017.03.025. [PMID: 28438492]
  • Scott M Knoerr, Jeremy A Durham, Debra A McNett. Development of collection, storage and analysis procedures for the quantification of cyclic volatile methylsiloxanes in wastewater treatment plant effluent and influent. Chemosphere. 2017 Sep; 182(?):114-121. doi: 10.1016/j.chemosphere.2017.04.136. [PMID: 28494354]
  • Arturo Trapote, Mariano García, Daniel Prats. The elimination of siloxanes from the biogas of a wastewater treatment plant by means of an adsorption process. Water science and technology : a journal of the International Association on Water Pollution Research. 2016 Dec; 74(12):2927-2934. doi: 10.2166/wst.2016.465. [PMID: 27997402]
  • Wolfgang Dekant, James E Klaunig. Toxicology of decamethylcyclopentasiloxane (D5). Regulatory toxicology and pharmacology : RTP. 2016 Feb; 74 Suppl(?):S67-76. doi: 10.1016/j.yrtph.2015.06.011. [PMID: 26111607]
  • Anne Fairbrother, G Allen Burton, Stephen J Klaine, David E Powell, Charles A Staples, Ellen M Mihaich, Kent B Woodburn, Frank A P C Gobas. Characterization of ecological risks from environmental releases of decamethylcyclopentasiloxane (D5). Environmental toxicology and chemistry. 2015 Dec; 34(12):2715-22. doi: 10.1002/etc.3041. [PMID: 26211518]
  • Hongliang Jia, Zifeng Zhang, Chaoqun Wang, Wen-Jun Hong, Yeqing Sun, Yi-Fan Li. Trophic transfer of methyl siloxanes in the marine food web from coastal area of Northern China. Environmental science & technology. 2015 Mar; 49(5):2833-40. doi: 10.1021/es505445e. [PMID: 25625298]
  • Janine Bruemmer, Raquel Falcon, Richard Greenwood, Graham A Mills, Colin Hastie, Chris Sparham, Roger van Egmond. Measurement of cyclic volatile methylsiloxanes in the aquatic environment using low-density polyethylene passive sampling devices using an in-field calibration study--challenges and guidance. Chemosphere. 2015 Mar; 122(?):38-44. doi: 10.1016/j.chemosphere.2014.10.069. [PMID: 25434262]
  • Nicholas A Warner, Therese H Nøst, Hector Andrade, Guttorm Christensen. Allometric relationships to liver tissue concentrations of cyclic volatile methyl siloxanes in Atlantic cod. Environmental pollution (Barking, Essex : 1987). 2014 Jul; 190(?):109-14. doi: 10.1016/j.envpol.2014.03.031. [PMID: 24747104]
  • Daryl J McGoldrick, Cecilia Chan, Ken G Drouillard, Michael J Keir, Mandi G Clark, Sean M Backus. Concentrations and trophic magnification of cyclic siloxanes in aquatic biota from the Western Basin of Lake Erie, Canada. Environmental pollution (Barking, Essex : 1987). 2014 Mar; 186(?):141-8. doi: 10.1016/j.envpol.2013.12.003. [PMID: 24374064]
  • Amelie Kierkegaard, Anders Bignert, Michael S McLachlan. Cyclic volatile methylsiloxanes in fish from the Baltic Sea. Chemosphere. 2013 Oct; 93(5):774-8. doi: 10.1016/j.chemosphere.2012.10.048. [PMID: 23177719]
  • Kent Woodburn, Kurt Drottar, Jean Domoradzki, Jeremy Durham, Debra McNett, Renee Jezowski. Determination of the dietary biomagnification of octamethylcyclotetrasiloxane and decamethylcyclopentasiloxane with the rainbow trout (Oncorhynchus mykiss). Chemosphere. 2013 Oct; 93(5):779-88. doi: 10.1016/j.chemosphere.2012.10.049. [PMID: 23200569]
  • W P Norwood, M Alaee, E Sverko, D Wang, M Brown, M Galicia. Decamethylcyclopentasiloxane (D5) spiked sediment: bioaccumulation and toxicity to the benthic invertebrate Hyalella azteca. Chemosphere. 2013 Oct; 93(5):805-12. doi: 10.1016/j.chemosphere.2012.10.052. [PMID: 23273736]
  • Amelie Kierkegaard, Anders Bignert, Michael S McLachlan. Bioaccumulation of decamethylcyclopentasiloxane in perch in Swedish lakes. Chemosphere. 2013 Oct; 93(5):789-93. doi: 10.1016/j.chemosphere.2012.10.050. [PMID: 23228907]
  • Lin Xu, Yali Shi, Yaqi Cai. Occurrence and fate of volatile siloxanes in a municipal wastewater treatment plant of Beijing, China. Water research. 2013 Feb; 47(2):715-24. doi: 10.1016/j.watres.2012.10.046. [PMID: 23182664]
  • Linda Hanssen, Nicholas A Warner, Tonje Braathen, Jon Ø Odland, Eiliv Lund, Evert Nieboer, Torkjel M Sandanger. Plasma concentrations of cyclic volatile methylsiloxanes (cVMS) in pregnant and postmenopausal Norwegian women and self-reported use of personal care products (PCPs). Environment international. 2013 Jan; 51(?):82-7. doi: 10.1016/j.envint.2012.10.008. [PMID: 23201819]
  • Daekyoung Kim, Hoonbae Kim, Haegyu Jang, Donggeun Jung, Heeyeop Chae. Characterization of low-k dielectric SiCOH films deposited with decamethylcyclopentasiloxane and cyclohexane. Journal of nanoscience and nanotechnology. 2012 Jul; 12(7):6040-4. doi: 10.1166/jnn.2012.6270. [PMID: 22966705]
  • Katrine Borgå, Eirik Fjeld, Amelie Kierkegaard, Michael S McLachlan. Food web accumulation of cyclic siloxanes in Lake Mjøsa, Norway. Environmental science & technology. 2012 Jun; 46(11):6347-54. doi: 10.1021/es300875d. [PMID: 22571757]
  • Jessica Velicogna, Ellyn Ritchie, Juliska Princz, Marie-Eve Lessard, Rick Scroggins. Ecotoxicity of siloxane D5 in soil. Chemosphere. 2012 Mar; 87(1):77-83. doi: 10.1016/j.chemosphere.2011.11.064. [PMID: 22197313]
  • Amelie Kierkegaard, Roger van Egmond, Michael S McLachlan. Cyclic volatile methylsiloxane bioaccumulation in flounder and ragworm in the Humber Estuary. Environmental science & technology. 2011 Jul; 45(14):5936-42. doi: 10.1021/es200707r. [PMID: 21662991]
  • Amelie Kierkegaard, Margaretha Adolfsson-Erici, Michael S McLachlan. Determination of cyclic volatile methylsiloxanes in biota with a purge and trap method. Analytical chemistry. 2010 Nov; 82(22):9573-8. doi: 10.1021/ac102406a. [PMID: 20954717]
  • Nicholas A Warner, Anita Evenset, Guttorm Christensen, Geir W Gabrielsen, Katrine Borgå, Henriette Leknes. Volatile siloxanes in the European arctic: assessment of sources and spatial distribution. Environmental science & technology. 2010 Oct; 44(19):7705-10. doi: 10.1021/es101617k. [PMID: 20836489]
  • Micaela B Reddy, Ivan D Dobrev, Debra A McNett, Joseph M Tobin, Mark J Utell, Paul E Morrow, Jeanne Y Domoradzki, Kathleen P Plotzke, Melvin E Andersen. Inhalation dosimetry modeling with decamethylcyclopentasiloxane in rats and humans. Toxicological sciences : an official journal of the Society of Toxicology. 2008 Oct; 105(2):275-85. doi: 10.1093/toxsci/kfn125. [PMID: 18583370]
  • Han-Shen Zhen, Jing Ge, Jie Liang, Qin Qiu, Zhi-Hua Song, Zhen-Guo Zhong, Wen-Hui Wang, Jian-Ping Jiang. [Analysis of the volatile oils chemical constituents of roots of Actinidia deliciosa]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials. 2008 May; 31(5):677-8. doi: ". [PMID: 18826142]
  • Joseph M Tobin, Debra A McNett, Jeremy A Durham, Kathleen P Plotzke. Disposition of decamethylcyclopentasiloxane in Fischer 344 rats following single or repeated inhalation exposure to 14C-decamethylcyclopentasiloxane (14C-D5). Inhalation toxicology. 2008 Mar; 20(5):513-31. doi: 10.1080/08958370801935075. [PMID: 18368622]
  • Marina L Jovanovic, Joan M McMahon, Debra A McNett, Joseph M Tobin, Kathleen P Plotzke. In vitro and in vivo percutaneous absorption of 14C-octamethylcyclotetrasiloxane (14C-D4) and 14C-decamethylcyclopentasiloxane (14C-D5). Regulatory toxicology and pharmacology : RTP. 2008 Mar; 50(2):239-48. doi: 10.1016/j.yrtph.2007.11.003. [PMID: 18178298]
  • Micaela B Reddy, Richard John Looney, Mark J Utell, Kathleen P Plotzke, Melvin E Andersen. Modeling of human dermal absorption of octamethylcyclotetrasiloxane (D(4)) and decamethylcyclopentasiloxane (D(5)). Toxicological sciences : an official journal of the Society of Toxicology. 2007 Oct; 99(2):422-31. doi: 10.1093/toxsci/kfm174. [PMID: 17630416]
  • Bin He, Stacey Rhodes-Brower, Michael R Miller, Albert E Munson, Dori R Germolec, Vickie R Walker, Kenneth S Korach, B Jean Meade. Octamethylcyclotetrasiloxane exhibits estrogenic activity in mice via ERalpha. Toxicology and applied pharmacology. 2003 Nov; 192(3):254-61. doi: 10.1016/s0041-008x(03)00282-5. [PMID: 14575643]
  • Daniela Flassbeck, Bettina Pfleiderer, Patrick Klemens, Klaus G Heumann, Elke Eltze, Alfred V Hirner. Determination of siloxanes, silicon, and platinum in tissues of women with silicone gel-filled implants. Analytical and bioanalytical chemistry. 2003 Feb; 375(3):356-62. doi: 10.1007/s00216-002-1694-z. [PMID: 12589499]
  • Sudarsanan Varaprath, Joan M McMahon, Kathleen P Plotzke. Metabolites of hexamethyldisiloxane and decamethylcyclopentasiloxane in Fischer 344 rat urine--a comparison of a linear and a cyclic siloxane. Drug metabolism and disposition: the biological fate of chemicals. 2003 Feb; 31(2):206-14. doi: 10.1124/dmd.31.2.206. [PMID: 12527702]
  • Magdalena Prokopowicz, Bogdan Banecki, Jerzy Lukasiak, Andrzej Przyjazny. The measurement of conformational stability of proteins adsorbed on siloxanes. Journal of biomaterials science. Polymer edition. 2003; 14(2):103-18. doi: 10.1163/156856203321142560. [PMID: 12661663]
  • D Flassbeck, B Pfleiderer, R Grümping, A V Hirner. Determination of low molecular weight silicones in plasma and blood of women after exposure to silicone breast implants by GC/MS. Analytical chemistry. 2001 Feb; 73(3):606-11. doi: 10.1021/ac000738z. [PMID: 11217769]
  • L A Burns-Naas, R W Mast, R G Meeks, P C Mann, P Thevenaz. Inhalation toxicology of decamethylcyclopentasiloxane (D5) following a 3-month nose-only exposure in Fischer 344 rats. Toxicological sciences : an official journal of the Society of Toxicology. 1998 Jun; 43(2):230-40. doi: 10.1006/toxs.1998.2441. [PMID: 9710964]