Eutypine (BioDeep_00000006783)
human metabolite
代谢物信息卡片
化学式: C12H10O2 (186.06807600000002)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C=C(C)C#Cc1cc(C=O)ccc1O
InChI: InChI=1S/C12H10O2/c1-9(2)3-5-11-7-10(8-13)4-6-12(11)14/h4,6-8,14H,1H2,2H3
描述信息
Eutypine is a member of the class of compounds known as hydroxybenzaldehydes. Hydroxybenzaldehydes are organic aromatic compounds containing a benzene ring carrying an aldehyde group and a hydroxyl group. Eutypine is practically insoluble (in water) and a very weakly acidic compound (based on its pKa). Eutypine can be found in common grape, which makes eutypine a potential biomarker for the consumption of this food product.
同义名列表
数据库引用编号
12 个数据库交叉引用编号
- KEGG: C08448
- PubChem: 129326
- HMDB: HMDB0301834
- Metlin: METLIN66984
- ChEMBL: CHEMBL501128
- KNApSAcK: C00001282
- foodb: FDB001486
- CAS: 121007-17-8
- PMhub: MS000019923
- PubChem: 10641
- NIKKAJI: J391.841F
- RefMet: Eutypine
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
3 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Anna Andolfi, Laura Mugnai, Jordi Luque, Giuseppe Surico, Alessio Cimmino, Antonio Evidente. Phytotoxins produced by fungi associated with grapevine trunk diseases.
Toxins.
2011 12; 3(12):1569-605. doi:
10.3390/toxins3121569
. [PMID: 22295177] - Gaetan Glauser, Katia Gindro, Juliane Fringeli, Jean-Pierre De Joffrey, Serge Rudaz, Jean-Luc Wolfender. Differential analysis of mycoalexins in confrontation zones of grapevine fungal pathogens by ultrahigh pressure liquid chromatography/time-of-flight mass spectrometry and capillary nuclear magnetic resonance.
Journal of agricultural and food chemistry.
2009 Feb; 57(4):1127-34. doi:
10.1021/jf8033539
. [PMID: 19182944] - Danilo Christen, Manuel Tharin, Sandrine Perrin-Cherioux, Eliane Abou-Mansour, Raphaël Tabacchi, Geneviève Défago. Transformation of Eutypa dieback and esca disease pathogen toxins by antagonistic fungal strains reveals a second detoxification pathway not present in Vitis vinifera.
Journal of agricultural and food chemistry.
2005 Sep; 53(18):7043-51. doi:
10.1021/jf050863h
. [PMID: 16131109] - Jean-François Chollet, Françoise Rocher, Cyril Jousse, Céline Delétage-Grandon, Georges Bashiardes, Jean-Louis Bonnemain. Synthesis and phloem mobility of acidic derivatives of the fungicide fenpiclonil.
Pest management science.
2004 Nov; 60(11):1063-72. doi:
10.1002/ps.906
. [PMID: 15532679] - Jong H Kim, Noreen Mahoney, Kathleen L Chan, Russell J Molyneux, Bruce C Campbell. Secondary metabolites of the grapevine pathogen Eutypa lata inhibit mitochondrial respiration, based on a model bioassay using the yeast Saccharomyces cerevisiae.
Current microbiology.
2004 Oct; 49(4):282-7. doi:
10.1007/s00284-004-4349-9
. [PMID: 15386117] - Noreen Mahoney, Richard Lardner, Russell J Molyneux, Eileen S Scott, Leverett R Smith, Thomas K Schoch. Phenolic and heterocyclic metabolite profiles of the grapevine pathogen Eutypa lata.
Phytochemistry.
2003 Sep; 64(2):475-84. doi:
10.1016/s0031-9422(03)00337-6
. [PMID: 12943765] - Maha Afifi, Ashraf El-Kereamy, Valérie Legrand, Christian Chervin, Marie-Carmen Monje, Françoise Nepveu, Jean-Paul Roustan. Control of anthocyanin biosynthesis pathway gene expression by eutypine, a toxin from Eutypa lata, in grape cell tissue cultures.
Journal of plant physiology.
2003 Aug; 160(8):971-5. doi:
10.1078/0176-1617-00921
. [PMID: 12964874] - Leverett R Smith, Noreen Mahoney, Russell J Molyneux. Synthesis and structure-phytotoxicity relationships of acetylenic phenols and chromene metabolites, and their analogues, from the grapevine pathogen Eutypa lata.
Journal of natural products.
2003 Feb; 66(2):169-76. doi:
10.1021/np020415t
. [PMID: 12608846] - Russell J Molyneux, Noreen Mahoney, Paul Bayman, Rosalind Y Wong, Kenneth Meyer, Nancy Irelan. Eutypa dieback in grapevines: differential production of acetylenic phenol metabolites by strains of Eutypa lata.
Journal of agricultural and food chemistry.
2002 Mar; 50(6):1393-9. doi:
10.1021/jf011215a
. [PMID: 11879009] - P Guillén, M Guis, G Martínez-Reina, S Colrat, S Dalmayrac, C Deswarte, M Bouzayen, J P Roustan, J Fallot, J C Pech, A Latché. A novel NADPH-dependent aldehyde reductase gene from Vigna radiata confers resistance to the grapevine fungal toxin eutypine.
The Plant journal : for cell and molecular biology.
1998 Nov; 16(3):335-43. doi:
10.1046/j.1365-313x.1998.00303.x
. [PMID: 9881154] - C Deswarte, J Eychenne, J Davy de Virville, J P Roustan, F Moreau, J Fallot. Protonophoric activity of eutypine, a toxin from Eutypa lata, in plant mitochondria.
Archives of biochemistry and biophysics.
1996 Oct; 334(2):200-5. doi:
10.1006/abbi.1996.0447
. [PMID: 8900393] - R Sekura, A Meister. Covalent interaction of L-2-amino-4-oxo-5-chloropentanoate at glutamate binding site of gamma-glutamylcysteine synthetase.
The Journal of biological chemistry.
1977 Apr; 252(8):2606-10. doi:
NULL
. [PMID: 15993]