Phaseolotoxin (BioDeep_00000006777)

   


代谢物信息卡片


(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-[[amino-(sulfoamino)phosphoryl]amino]pentanoyl]amino]propanoyl]amino]-6-(diaminomethylideneamino)hexanoic acid

化学式: C15H34N9O8PS (531.1988574)
中文名称:
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(=O)NC(CCCCN=C(N)N)C(=O)O)NC(=O)C(CCCNP(=O)(N)NS(=O)(=O)O)N
InChI: InChI=1S/C15H34N9O8PS/c1-9(12(25)23-11(14(27)28)6-2-3-7-20-15(17)18)22-13(26)10(16)5-4-8-21-33(19,29)24-34(30,31)32/h9-11H,2-8,16H2,1H3,(H,22,26)(H,23,25)(H,27,28)(H4,17,18,20)(H,30,31,32)(H4,19,21,24,29)/t9-,10-,11-,33?/m0/s1

描述信息

同义名列表

4 个代谢物同义名

(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-[[amino-(sulfoamino)phosphoryl]amino]pentanoyl]amino]propanoyl]amino]-6-(diaminomethylideneamino)hexanoic acid; Phaseolotoxin; N5-[Amino(sulfoamino)phosphinyl]-L-ornithyl-L-alanyl-N6-(aminoiminomethyl)-L-lysine; N5-[Amino(sulfoamino)phosphinyl]-L-ornithyl-L-alanyl-N6-(aminoiminomethyl)-L-lysine; Phaseolotoxin



数据库引用编号

11 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Takashi Fujikawa, Hiroyuki Sawada. Genome analysis of Pseudomonas syringae pv. actinidiae biovar 6, which produces the phytotoxins, phaseolotoxin and coronatine. Scientific reports. 2019 03; 9(1):3836. doi: 10.1038/s41598-019-40754-9. [PMID: 30846809]
  • Selene Aguilera, Ariel Alvarez-Morales, Jesús Murillo, José Luis Hernández-Flores, Jaime Bravo, Susana De la Torre-Zavala. Temperature-mediated biosynthesis of the phytotoxin phaseolotoxin by Pseudomonas syringae pv. phaseolicola depends on the autoregulated expression of the phtABC genes. PloS one. 2017; 12(6):e0178441. doi: 10.1371/journal.pone.0178441. [PMID: 28570637]
  • Selene Aguilera, Susana De la Torre-Zavala, José Luis Hernández-Flores, Jesús Murillo, Jaime Bravo, Ariel Alvarez-Morales. Expression of the gene for resistance to phaseolotoxin (argK) depends on the activity of genes phtABC in Pseudomonas syringae pv. phaseolicola. PloS one. 2012; 7(10):e46815. doi: 10.1371/journal.pone.0046815. [PMID: 23056465]
  • Jesús Murillo, Leire Bardaji, Laura Navarro de la Fuente, Maria Elena Führer, Selene Aguilera, Ariel Alvarez-Morales. Variation in conservation of the cluster for biosynthesis of the phytotoxin phaseolotoxin in Pseudomonas syringae suggests at least two events of horizontal acquisition. Research in microbiology. 2011 Apr; 162(3):253-61. doi: 10.1016/j.resmic.2010.10.011. [PMID: 21187143]
  • Simone Marcelletti, Patrizia Ferrante, Milena Petriccione, Giuseppe Firrao, Marco Scortichini. Pseudomonas syringae pv. actinidiae draft genomes comparison reveal strain-specific features involved in adaptation and virulence to Actinidia species. PloS one. 2011; 6(11):e27297. doi: 10.1371/journal.pone.0027297. [PMID: 22132095]
  • Min Seok Cho, Yong Ho Jeon, Man Jung Kang, Hong Il Ahn, Hyung-Jin Baek, Young Wang Na, Yu Mi Choi, Tae San Kim, Dong Suk Park. Sensitive and specific detection of phaseolotoxigenic and nontoxigenic strains of Pseudomonas syringae pv. phaseolicola by TaqMan real-time PCR using site-specific recombinase gene sequences. Microbiological research. 2010 Sep; 165(7):565-72. doi: 10.1016/j.micres.2009.11.001. [PMID: 20022231]
  • Alejandro Hernández-Morales, Susana De la Torre-Zavala, Enrique Ibarra-Laclette, José Luis Hernández-Flores, Alba Estela Jofre-Garfias, Agustino Martínez-Antonio, Ariel Alvarez-Morales. Transcriptional profile of Pseudomonas syringae pv. phaseolicola NPS3121 in response to tissue extracts from a susceptible Phaseolus vulgaris L. cultivar. BMC microbiology. 2009 Dec; 9(?):257. doi: 10.1186/1471-2180-9-257. [PMID: 20003402]
  • Jesús Caballero-Mellado. [Agriculture microbiology and microbe interaction with plants]. Revista latinoamericana de microbiologia. 2006 Apr; 48(2):154-61. doi: . [PMID: 17578087]
  • Daniela Dietrich, Ulrich Hammes, Kathrin Thor, Marianne Suter-Grotemeyer, Ricardo Flückiger, Alan J Slusarenko, John M Ward, Doris Rentsch. AtPTR1, a plasma membrane peptide transporter expressed during seed germination and in vascular tissue of Arabidopsis. The Plant journal : for cell and molecular biology. 2004 Nov; 40(4):488-99. doi: 10.1111/j.1365-313x.2004.02224.x. [PMID: 15500465]
  • André S Bachmann, Ronghui Xu, Lal Ratnapala, Suresh S Patil. Inhibitory effects of phaseolotoxin on proliferation of leukemia cells HL-60, K-562 and L1210 and pancreatic cells RIN-m5F. Leukemia research. 2004 Mar; 28(3):301-6. doi: 10.1016/j.leukres.2003.07.002. [PMID: 14687626]
  • José A Oguiza, Arantza Rico, Luis A Rivas, Laurent Sutra, Alan Vivian, Jesús Murillo. Pseudomonas syringae pv. phaseolicola can be separated into two genetic lineages distinguished by the possession of the phaseolotoxin biosynthetic cluster. Microbiology (Reading, England). 2004 Feb; 150(Pt 2):473-482. doi: 10.1099/mic.0.26635-0. [PMID: 14766926]
  • G Hernández-Guzmán, A Alvarez-Morales. Isolation and characterization of the gene coding for the amidinotransferase involved in the biosynthesis of phaseolotoxin in Pseudomonas syringae pv. phaseolicola. Molecular plant-microbe interactions : MPMI. 2001 Apr; 14(4):545-54. doi: 10.1094/mpmi.2001.14.4.545. [PMID: 11310742]
  • K B Rowley, R Xu, S S Patil. Molecular analysis of thermoregulation of phaseolotoxin-resistant ornithine carbamoyltransferase (argK) from Pseudomonas syringae pv. phaseolicola. Molecular plant-microbe interactions : MPMI. 2000 Oct; 13(10):1071-80. doi: 10.1094/mpmi.2000.13.10.1071. [PMID: 11043468]
  • H Sawada, F Suzuki, I Matsuda, N Saitou. Phylogenetic analysis of Pseudomonas syringae pathovars suggests the horizontal gene transfer of argK and the evolutionary stability of hrp gene cluster. Journal of molecular evolution. 1999 Nov; 49(5):627-44. doi: 10.1007/pl00006584. [PMID: 10552044]
  • C L Bender, F Alarcón-Chaidez, D C Gross. Pseudomonas syringae phytotoxins: mode of action, regulation, and biosynthesis by peptide and polyketide synthetases. Microbiology and molecular biology reviews : MMBR. 1999 Jun; 63(2):266-92. doi: 10.1128/mmbr.63.2.266-292.1999. [PMID: 10357851]
  • Y X Zhang, S S Patil. The phtE locus in the phaseolotoxin gene cluster has ORFs with homologies to genes encoding amino acid transferases, the AraC family of transcriptional factors, and fatty acid desaturases. Molecular plant-microbe interactions : MPMI. 1997 Nov; 10(8):947-60. doi: 10.1094/mpmi.1997.10.8.947. [PMID: 9353942]
  • E Hatziloukas, N J Panopoulos, S Delis, D E Prosen, N W Schaad. An open reading frame in the approximately 28-kb tox-argk gene cluster encodes a polypeptide with homology to fatty acid desaturases. Gene. 1995 Dec; 166(1):83-7. doi: 10.1016/0378-1119(95)00569-5. [PMID: 8529898]
  • N Missaleva, G Petri, G Reuter, E Szöke, U Markish. Influence of phaseolotoxin on the alkaloid accumulation in Datura innoxia Mill. Acta pharmaceutica Hungarica. 1993 Nov; 63(6):307-12. doi: ". [PMID: 8116450]
  • Y Zhang, K B Rowley, S S Patil. Genetic organization of a cluster of genes involved in the production of phaseolotoxin, a toxin produced by Pseudomonas syringae pv. phaseolicola. Journal of bacteriology. 1993 Oct; 175(20):6451-8. doi: 10.1128/jb.175.20.6451-6458.1993. [PMID: 8407821]
  • K B Rowley, D E Clements, M Mandel, T Humphreys, S S Patil. Multiple copies of a DNA sequence from Pseudomonas syringae pathovar phaseolicola abolish thermoregulation of phaseolotoxin production. Molecular microbiology. 1993 May; 8(3):625-35. doi: 10.1111/j.1365-2958.1993.tb01606.x. [PMID: 8326870]
  • E Hatziloukas, N J Panopoulos. Origin, structure, and regulation of argK, encoding the phaseolotoxin-resistant ornithine carbamoyltransferase in Pseudomonas syringae pv. phaseolicola, and functional expression of argK in transgenic tobacco. Journal of bacteriology. 1992 Sep; 174(18):5895-909. doi: 10.1128/jb.174.18.5895-5909.1992. [PMID: 1522066]
  • J M de la Fuente-Martínez, G Mosqueda-Cano, A Alvarez-Morales, L Herrera-Estrella. Expression of a bacterial phaseolotoxin-resistant ornithyl transcarbamylase in transgenic tobacco confers resistance to Pseudomonas syringae pv. phaseolicola. Bio/technology (Nature Publishing Company). 1992 Aug; 10(8):905-9. doi: 10.1038/nbt0892-905. [PMID: 1368986]
  • H V Kamdar, K B Rowley, D Clements, S S Patil. Pseudomonas syringae pv. phaseolicola genomic clones harboring heterologous DNA sequences suppress the same phaseolotoxin-deficient mutants. Journal of bacteriology. 1991 Feb; 173(3):1073-9. doi: 10.1128/jb.173.3.1073-1079.1991. [PMID: 1991709]
  • B Völksch, F Laplace, W Fritsche. [Studies on the variability of the phaseolotoxin production by Pseudomonas syringae pv. phaseolicola]. Zentralblatt fur Mikrobiologie. 1984; 139(2):109-18. doi: ". [PMID: 6428075]