Thieno[3,2-b]pyridine (BioDeep_00000677425)
代谢物信息卡片
Thieno[3,2-b]pyridine
化学式: C7H5NS (135.014269)
中文名称: 噻吩并[3,2-b]吡啶
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC2=C(C=CS2)N=C1
InChI: InChI=1S/C7H5NS/c1-2-7-6(8-4-1)3-5-9-7/h1-5H
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Yu Wu, Yimiao Song, Yuesong Pan, Yong Gong, Yilun Zhou. Long-term and short-term duration of thienopyridine therapy after coronary stenting in patients with chronic kidney disease a meta-analysis of literature studies.
Platelets.
2020 May; 31(4):483-489. doi:
10.1080/09537104.2019.1647528. [PMID: 31357901] - Pei-Jui Luo, Xi-Hsuan Lin, Chung-Chi Lin, Jiing-Chyuan Luo, Hsiao-Yun Hu, Po-Hsiang Ting, Ming-Chih Hou. Risk factors for upper gastrointestinal bleeding among aspirin users: An old issue with new findings from a population-based cohort study.
Journal of the Formosan Medical Association = Taiwan yi zhi.
2019 May; 118(5):939-944. doi:
10.1016/j.jfma.2018.10.007. [PMID: 30366771] - Y V Madhavi, Nikhil Gaikwad, Veera Ganesh Yerra, Anil Kumar Kalvala, Srinivas Nanduri, Ashutosh Kumar. Targeting AMPK in Diabetes and Diabetic Complications: Energy Homeostasis, Autophagy and Mitochondrial Health.
Current medicinal chemistry.
2019; 26(27):5207-5229. doi:
10.2174/0929867325666180406120051. [PMID: 29623826] - Bernadeta Chyrchel, Anna Drożdż, Dorota Długosz, Ewa Ł Stępień, Andrzej Surdacki. Platelet Reactivity And Circulating Platelet-Derived Microvesicles Are Differently Affected By P2Y12 Receptor Antagonists.
International journal of medical sciences.
2019; 16(2):264-275. doi:
10.7150/ijms.28580. [PMID: 30745807] - Ryota Niikura, Atsuo Yamada, Mitsuhiro Fujishiro, Kiyohito Tanaka, Koji Matsuda, Yutaka Saito, Kazuo Ohtsuka, Ichiro Oda, Chikatoshi Katada, Masayuki Kato, Mitsuhiro Kida, Kiyonori Kobayashi, Shu Hoteya, Takahiro Horimatsu, Shinya Kodashima, Takahisa Matsuda, Manabu Muto, Hironori Yamamoto, Shomei Ryozawa, Ryuichi Iwakiri, Hiromu Kutsumi, Hiroaki Miyata, Mototsugu Kato, Ken Haruma, Kazuma Fujimoto, Naomi Uemura, Michio Kaminishi, Tomohiro Shinozaki, Hisao Tajiri, Kazuhiko Koike. The Effects of Direct Oral Anticoagulants, Warfarin, Aspirin and Thienopyridine on the Performance of Immunochemical, Faecal, Occult Blood Tests.
Digestion.
2019; 100(2):117-126. doi:
10.1159/000494251. [PMID: 30408803] - Ana Rita O Rodrigues, Pedro M F Mendes, Pedro M L Silva, V A Machado, Bernardo G Almeida, J P Araújo, Maria-João R P Queiroz, Elisabete M S Castanheira, Paulo J G Coutinho. Solid and aqueous magnetoliposomes as nanocarriers for a new potential drug active against breast cancer.
Colloids and surfaces. B, Biointerfaces.
2017 Oct; 158(?):460-468. doi:
10.1016/j.colsurfb.2017.07.015. [PMID: 28732311] - Yosuke Tatami, Hideki Ishii, Toshijiro Aoki, Kazuhiro Harada, Kenshi Hirayama, Yohei Shibata, Takuya Sumi, Yosuke Negishi, Kazuhiro Kawashima, Ayako Kunimura, Toshiki Kawamiya, Dai Yamamoto, Susumu Suzuki, Toyoaki Murohara. Decreased Serum Albumin Predicts Bleeding Events in Patients on Antiplatelet Therapy After Percutaneous Coronary Intervention.
Circulation journal : official journal of the Japanese Circulation Society.
2017 Jun; 81(7):999-1005. doi:
10.1253/circj.cj-17-0015. [PMID: 28344205] - Elizabeth E Bollinger, Melissa A Spera, Daniel L Raines. Device-assisted Enteroscopy for Obscure Gastrointestinal Bleeding in the Setting of Thienopyridine Antiplatelet Therapy.
Journal of clinical gastroenterology.
2017 01; 51(1):e1-e4. doi:
10.1097/mcg.0000000000000537. [PMID: 27136961] - Dimitrios Alexopoulos, Periklis Davlouros, Grigorios Tsigkas, Nikolaos Koutsogiannis, Athena Hassapi, Christos Scortsanitis, Ioanna Pentara, Chrysoula Vogiatzi, Ioanna Xanthopoulou. Comparison of Ticagrelor Versus Thienopyridine Loading Effect on Fractional Flow Reserve in Patients With Coronary Artery Disease.
The American journal of cardiology.
2016 Jan; 117(1):22-8. doi:
10.1016/j.amjcard.2015.09.044. [PMID: 26552503] - Shuang Zhi, Guangping Xia, Ying Liu, Zunwei Tao, Ligong Chen, Dengke Liu. Synthesis of the alkylated active metabolite of tipidogrel.
Bioorganic & medicinal chemistry letters.
2015 Apr; 25(8):1718-1723. doi:
10.1016/j.bmcl.2015.02.072. [PMID: 25801935] - Tara I Chang, Maria E Montez-Rath, Jenny I Shen, Matthew D Solomon, Glenn M Chertow, Wolfgang C Winkelmayer. Thienopyridine use after coronary stenting in low income patients enrolled in medicare part D receiving maintenance dialysis.
Journal of the American Heart Association.
2014 Oct; 3(5):e001356. doi:
10.1161/jaha.114.001356. [PMID: 25336465] - Robert F Storey, Jayaprakash Kotha, Susan S Smyth, David J Moliterno, Tyrus L Rorick, Tiziano Moccetti, Marco Valgimigli, Jean Pierre Dery, Jan H Cornel, Gregory S Thomas, Kurt Huber, Robert A Harrington, Edward Hord, Heather M Judge, Edmond Chen, John Strony, Kenneth W Mahaffey, Pierluigi Tricoci, Richard C Becker, Lisa K Jennings. Effects of vorapaxar on platelet reactivity and biomarker expression in non-ST-elevation acute coronary syndromes. The TRACER Pharmacodynamic Substudy.
Thrombosis and haemostasis.
2014 May; 111(5):883-91. doi:
10.1160/th13-07-0624. [PMID: 24402559] - Tsukasa Ohmori, Yuichiro Yano, Asuka Sakata, Tomokazu Ikemoto, Masahisa Shimpo, Seiji Madoiwa, Takaaki Katsuki, Jun Mimuro, Kazuyuki Shimada, Kazuomi Kario, Yoichi Sakata. Lack of association between serum paraoxonase-1 activity and residual platelet aggregation during dual anti-platelet therapy.
Thrombosis research.
2012 Apr; 129(4):e36-40. doi:
10.1016/j.thromres.2011.10.033. [PMID: 22115701] - Jean-Sébastien Hulot, Jean-Philippe Collet, Gilles Montalescot. Thienopyridine-associated drug-drug interactions: pharmacologic mechanisms and clinical relevance.
Current cardiology reports.
2011 Oct; 13(5):451-8. doi:
10.1007/s11886-011-0206-1. [PMID: 21826477] - Yoshie Uchida, Fumiaki Mori, Hiroshi Ogawa, Atsushi Takagi, Nobuhisa Hagiwara. Impact of anticoagulant therapy with dual antiplatelet therapy on prognosis after treatment with drug-eluting coronary stents.
Journal of cardiology.
2010 May; 55(3):362-9. doi:
10.1016/j.jjcc.2009.12.014. [PMID: 20350510] - Paul P Dobesh. Pharmacokinetics and pharmacodynamics of prasugrel, a thienopyridine P2Y12 inhibitor.
Pharmacotherapy.
2009 Sep; 29(9):1089-102. doi:
10.1592/phco.29.9.1089. [PMID: 19698014] - Jo Ann Janovick, Guadalupe Maya-Núñez, Alfredo Ulloa-Aguirre, Ilpo T Huhtaniemi, James A Dias, Pieter Verbost, P Michael Conn. Increased plasma membrane expression of human follicle-stimulating hormone receptor by a small molecule thienopyr(im)idine.
Molecular and cellular endocrinology.
2009 Jan; 298(1-2):84-8. doi:
10.1016/j.mce.2008.09.015. [PMID: 18848862] - David Erlinge, Christoph Varenhorst, Oscar O Braun, Stefan James, Kenneth J Winters, Joseph A Jakubowski, John T Brandt, Atsuhiro Sugidachi, Agneta Siegbahn, Lars Wallentin. Patients with poor responsiveness to thienopyridine treatment or with diabetes have lower levels of circulating active metabolite, but their platelets respond normally to active metabolite added ex vivo.
Journal of the American College of Cardiology.
2008 Dec; 52(24):1968-77. doi:
10.1016/j.jacc.2008.07.068. [PMID: 19055987] - Charles L Bennett, Benjamin Kim, Anaadriana Zakarija, Nicholas Bandarenko, Dilip K Pandey, Charlie G Buffie, June M McKoy, Amul D Tevar, John F Cursio, Paul R Yarnold, Hau C Kwaan, Davide De Masi, Ravindra Sarode, Thomas J Raife, Joseph E Kiss, Dennis W Raisch, Charles Davidson, J Evan Sadler, Thomas L Ortel, X Long Zheng, Seiji Kato, Masanori Matsumoto, Masahito Uemura, Yoshihiro Fujimura. Two mechanistic pathways for thienopyridine-associated thrombotic thrombocytopenic purpura: a report from the SERF-TTP Research Group and the RADAR Project.
Journal of the American College of Cardiology.
2007 Sep; 50(12):1138-43. doi:
10.1016/j.jacc.2007.04.093. [PMID: 17868804] - Nagy A Farid, Richard L Smith, Todd A Gillespie, T James Rash, Patrick E Blair, Atsushi Kurihara, Mark J Goldberg. The disposition of prasugrel, a novel thienopyridine, in humans.
Drug metabolism and disposition: the biological fate of chemicals.
2007 Jul; 35(7):1096-104. doi:
10.1124/dmd.106.014522. [PMID: 17403916] - K Hagihara, A Kurihara, K Kawai, M Kazui, M Takahashi, K Kawabata, N A Farid, T Ikeda. Absorption, distribution and excretion of the new thienopyridine agent prasugrel in rats.
Xenobiotica; the fate of foreign compounds in biological systems.
2007 Jul; 37(7):788-801. doi:
10.1080/00498250701397721. [PMID: 17620223] - Michael J Lim, Kim A Eagle, Joel M Gore, Frederick A Anderson, Omar H Dabbous, Rajendra H Mehta, Christopher B Granger, Keith A A Fox, Frederick A Spencer, Robert J Goldberg. Treating patients with acute coronary syndromes with aggressive antiplatelet therapy (from the Global Registry of Acute Coronary Events).
The American journal of cardiology.
2005 Oct; 96(7):917-21. doi:
10.1016/j.amjcard.2005.05.047. [PMID: 16188516] - Pierre Savi, Jean-Marc Herbert. Clopidogrel and ticlopidine: P2Y12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis.
Seminars in thrombosis and hemostasis.
2005 Apr; 31(2):174-83. doi:
10.1055/s-2005-869523. [PMID: 15852221] - G Christ, M Nikfardjam, R Huber-Beckmann, M Gottsauner-Wolf, D Glogar, B R Binder, J Wojta, K Huber. Predictive value of plasma plasminogen activator inhibitor-1 for coronary restenosis: dependence on stent implantation and antithrombotic medication.
Journal of thrombosis and haemostasis : JTH.
2005 Feb; 3(2):233-9. doi:
10.1111/j.1538-7836.2004.01062.x. [PMID: 15670026]