Hexaminolevulinate Hydrochloride (BioDeep_00000677071)
代谢物信息卡片
化学式: C11H22ClNO3 (251.1288132)
中文名称: 盐酸氨基乙酰丙酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCCCCOC(=O)CCC(=O)CN.Cl
InChI: 1H
数据库引用编号
5 个数据库交叉引用编号
- KEGGdrug: D81726
- KEGGdrug: D04436
- PubChem: 6433082
- ChEMBL: CHEMBL1201785
- CAS: 140898-91-5
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- Hang Zhao, Panxin Peng, Zhenkai Luo, Hailong Liu, Junwei Sun, Xuming Wang, Qiang Jia, Zhihao Yang. Comparison of hexaminolevulinate (HAL) -guided versus white light transurethral resection for NMIBC: A systematic review and meta-analysis of randomized controlled trials.
Photodiagnosis and photodynamic therapy.
2023 Mar; 41(?):103220. doi:
10.1016/j.pdpdt.2022.103220
. [PMID: 36462704] - Makito Miyake, Yasushi Nakai, Nobutaka Nishimura, Sayuri Ohnishi, Yuki Oda, Tomomi Fujii, Takuya Owari, Shunta Hori, Yosuke Morizawa, Daisuke Gotoh, Satoshi Anai, Kazumasa Torimoto, Nobumichi Tanaka, Yoshihiko Hirao, Kiyohide Fujimoto. Hexylaminolevulinate-mediated fluorescent urine cytology with a novel automated detection technology for screening and surveillance of bladder cancer.
BJU international.
2021 08; 128(2):244-253. doi:
10.1111/bju.15368
. [PMID: 33580627] - Kit Man Chan, Jonathan Gleadle, Jordan Li, Thomas Danny Michl, Krasimir Vasilev, Melanie MacGregor. Improving hexaminolevulinate enabled cancer cell detection in liquid biopsy immunosensors.
Scientific reports.
2021 03; 11(1):7283. doi:
10.1038/s41598-021-86649-6
. [PMID: 33790357] - Hanieh Safizadeh Shirazi, Kit Man Chan, Julien Rouget, Kola Ostrikov, Kym McNicholas, Jordan Li, Lisa Butler, Jonathan M Gleadle, Krasimir Vasilev, Melanie MacGregor. Plasma enabled devices for the selective capture and photodynamic identification of prostate cancer cells.
Biointerphases.
2020 05; 15(3):031002. doi:
10.1116/6.0000047
. [PMID: 32414237] - Vito Lacetera, Ubaldo Cantoro, Lorenzo Montesi, Daniele Cantoro, Bernardo Cervelli, Antonio Cicetti, Giuliana Gabrielloni, Domenico Milella, Michele Montesi, Roberto Morcellini, Gianni Parri, Emilio Recanatini, Valerio Beatrici. Blue light cystoscopy with hexylaminolevulinate: Our 7 years experience.
Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica.
2017 Mar; 89(1):39-41. doi:
10.4081/aiua.2017.1.39
. [PMID: 28403596] - Petru Octavian Drăgoescu, Ştefania Tudorache, Andrei Ioan Drocaş, George Mitroi, Andrei Pănuş, Nicoleta Alice Marilena Drăgoescu, Cristian Meşină, Cosmin Daniel Mititelu, Andreea Doriana Stănculescu, Guleed Mohamed, Paul Ioan Tomescu. Improved diagnosis and long-term recurrence rate reduction for non-muscle-invasive bladder cancer patients undergoing fluorescent hexylaminolevulinate photodynamic diagnosis.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.
2017; 58(4):1279-1283. doi:
NULL
. [PMID: 29556618] - Yann Neuzillet, Charlotte Methorst, Marc Schneider, Thierry Lebret, Mathieu Rouanne, Camelia Radulescu, Vincent Molinie, Jean-François Dreyfus, Veronique Pelcat, Henry Botto. Assessment of diagnostic gain with hexaminolevulinate (HAL) in the setting of newly diagnosed non-muscle-invasive bladder cancer with positive results on urine cytology.
Urologic oncology.
2014 Nov; 32(8):1135-40. doi:
10.1016/j.urolonc.2014.04.005
. [PMID: 25023786] - J Alfred Witjes, Marek Babjuk, Paolo Gontero, Didier Jacqmin, Alexander Karl, Stephan Kruck, Paramananthan Mariappan, Juan Palou Redorta, Arnulf Stenzl, Roland van Velthoven, Dirk Zaak. Clinical and cost effectiveness of hexaminolevulinate-guided blue-light cystoscopy: evidence review and updated expert recommendations.
European urology.
2014 Nov; 66(5):863-71. doi:
10.1016/j.eururo.2014.06.037
. [PMID: 25001887] - Siamak Daneshmand, Anne K Schuckman, Bernard H Bochner, Michael S Cookson, Tracy M Downs, Leonard G Gomella, H Barton Grossman, Ashish M Kamat, Badrinath R Konety, Cheryl T Lee, Kamal S Pohar, Raj S Pruthi, Matthew J Resnick, Norm D Smith, J Alfred Witjes, Mark P Schoenberg, Gary D Steinberg. Hexaminolevulinate blue-light cystoscopy in non-muscle-invasive bladder cancer: review of the clinical evidence and consensus statement on appropriate use in the USA.
Nature reviews. Urology.
2014 Oct; 11(10):589-96. doi:
10.1038/nrurol.2014.245
. [PMID: 25245244] - Carla Martoccia, Matthieu Zellweger, Blaise Lovisa, Patrice Jichlinski, Hubert van den Bergh, Georges Wagnières. Optical spectroscopy of the bladder washout fluid to optimize fluorescence cystoscopy with Hexvix®.
Journal of biomedical optics.
2014 Sep; 19(9):97002. doi:
10.1117/1.jbo.19.9.097002
. [PMID: 25208244] - Francesco Soria, Alberto Gurioli, Francesca Peraldo, Marco Oderda, Simone Giona, Emanuele Ambrosini, Bruno Frea, Paolo Gontero. Innovations in the endoscopic management of bladder cancer: is the era of white light cystoscopy over.
Urologia.
2013 Jun; 80 Spec No 1(?):1-8. doi:
10.5301/ru.2013.11151
. [PMID: 23813287] - S Tauber, C Brunken, M Vierbuchen. [Expression of the tumormarker p16INK4a in cytology specimens of the urinary bladder. A new means for early recognition and surveillance of urothelial cancer].
Der Urologe. Ausg. A.
2011 Sep; 50(9):1130-3. doi:
10.1007/s00120-011-2693-5
. [PMID: 21847682] - F Vom Dorp, S Tschirdewahn, T Olbricht, T Szarvas, H Rübben. [Photodynamic diagnostics of bladder carcinoma].
Der Urologe. Ausg. A.
2011 Sep; 50(9):1068-71. doi:
10.1007/s00120-011-2696-2
. [PMID: 21845422] - J Alfred Witjes, Juan Palou Redorta, Didier Jacqmin, Frank Sofras, Per-Uno Malmström, Claus Riedl, Dieter Jocham, Giario Conti, Francesco Montorsi, Harm C Arentsen, Dirk Zaak, A Hugh Mostafid, Marko Babjuk. Hexaminolevulinate-guided fluorescence cystoscopy in the diagnosis and follow-up of patients with non-muscle-invasive bladder cancer: review of the evidence and recommendations.
European urology.
2010 Apr; 57(4):607-14. doi:
10.1016/j.eururo.2010.01.025
. [PMID: 20116164] - Eleanor R Ray, Kathryn Chatterton, M Shamim Khan, Ashish Chandra, Kay Thomas, Prokar Dasgupta, Tim S O'Brien. Hexylaminolaevulinate fluorescence cystoscopy in patients previously treated with intravesical bacille Calmette-Guérin.
BJU international.
2010 Mar; 105(6):789-94. doi:
10.1111/j.1464-410x.2009.08839.x
. [PMID: 19832725] - Eleanor R Ray, Kathryn Chatterton, Mohammed S Khan, Kay Thomas, Ashish Chandra, Tim S O'Brien. Hexylaminolaevulinate 'blue light' fluorescence cystoscopy in the investigation of clinically unconfirmed positive urine cytology.
BJU international.
2009 May; 103(10):1363-7. doi:
10.1111/j.1464-410x.2008.08238.x
. [PMID: 19076151] - José M Abascal Junquera, Miguel Hevia Suárez, José M Abascal García, Cristina Estébanez, Aurora Astudillo, Ramón Abascal. [Initial experience in the diagnosis and treatment of superficial bladder tumors with Hexvix].
Archivos espanoles de urologia.
2008 May; 61(4):475-82; discussion 482. doi:
10.4321/s0004-06142008000400003
. [PMID: 18592765] - H Stepp, R Waidelich. [Fluorescence diagnosis and photodynamic therapy in urology].
Aktuelle Urologie.
2007 Nov; 38(6):455-64. doi:
10.1055/s-2007-980149
. [PMID: 17987533] - B Cunderlíková, R Wahlqvist, A Berner, V Vasovic, T Warloe, J M Nesland, Q Peng. Detection of urinary bladder cancer with flow cytometry and hexaminolevulinate in urine samples.
Cytopathology : official journal of the British Society for Clinical Cytology.
2007 Apr; 18(2):87-95. doi:
10.1111/j.1365-2303.2007.00436.x
. [PMID: 17397493] - L Colapaoli, J Thorsen, A Nopp, A B Guttormsen. A case of anaphylactic shock possibly caused by intravesical Hexvix.
Acta anaesthesiologica Scandinavica.
2006 Oct; 50(9):1165-7. doi:
10.1111/j.1399-6576.2006.01110.x
. [PMID: 16987348] - NULL. Hexyl aminolevulinate: 5-ALA hexylester, 5-ALA hexylesther, aminolevulinic acid hexyl ester, hexaminolevulinate, hexyl 5-aminolevulinate, P 1206.
Drugs in R&D.
2005; 6(4):235-8. doi:
10.2165/00126839-200506040-00007
. [PMID: 15991884] - Qing-Guang Ren, Su-Min Wu, Qian Peng, Ji-Yao Chen. Comparison of 5-aminolevulinic acid and its hexylester mediated photodynamic action on human hepatoma cells.
Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica.
2002 Sep; 34(5):650-4. doi:
"
. [PMID: 12198571] - A Casas, C Perotti, M Saccoliti, P Sacca, H Fukuda, A M del C Batlle. ALA and ALA hexyl ester in free and liposomal formulations for the photosensitisation of tumour organ cultures.
British journal of cancer.
2002 Mar; 86(5):837-42. doi:
10.1038/sj.bjc.6600144
. [PMID: 11875750] - A Casas, C Perotti, H Fukuda, L Rogers, A R Butler, A Batlle. ALA and ALA hexyl ester-induced porphyrin synthesis in chemically induced skin tumours: the role of different vehicles on improving photosensitization.
British journal of cancer.
2001 Nov; 85(11):1794-800. doi:
10.1054/bjoc.2001.2156
. [PMID: 11742504]