CID 25212181 (BioDeep_00000675745)
代谢物信息卡片
2-(chloromethyl)oxirane,N,N,N,N-tetrakis(3-aminopropyl)butane-1,4-diamine
化学式: C19H45ClN6O (408.334319)
中文名称: N,N,N’,N’-四(3-氨基丙基)-1,4-丁二胺 2-(氯甲基)环氧乙烷聚合物
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1C(O1)CCl.C(CCN(CCCN)CCCN)CN(CCCN)CCCN
InChI: 3H,1-2H2
描述信息
同义名列表
相关代谢途径
Reactome(0)
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Nobuo Nagano, Ayako Minegishi, Kyoko Ito, Tetsuo Ando, Takaaki Tsutsui, Tetsuya Ogawa. Phosphate Binders Derived from Natural Ores Contain Many Kinds of Metallic Elements Besides Their Active Ingredient Metals.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2018 Dec; 22(6):630-634. doi:
10.1111/1744-9987.12704. [PMID: 29989312] - Satoru Mitsuboshi, Hitoshi Yamada, Kazuhiko Nagai, Hideo Okajima. [Low Continuity Rate of Sucroferric Oxyhydroxide among Japanese Hemodialysis Patients with High Phosphate Binder Pill Burden].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan.
2018; 138(1):135-139. doi:
10.1248/yakushi.17-00180. [PMID: 29311459] - Tadao Akizawa, Junko Tsukada, Chisato Kameoka, Kentarou Kuroishi, Yusuke Yamaguchi. Long-Term Safety and Efficacy of Bixalomer in Hyperphosphatemic Patients With Chronic Kidney Disease Not on Dialysis.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2017 Apr; 21(2):173-179. doi:
10.1111/1744-9987.12502. [PMID: 28194884] - Tadao Akizawa, Hideki Origasa, Chisato Kameoka, Junko Tsukada, Kentarou Kuroishi, Yusuke Yamaguchi. Bixalomer in Hyperphosphatemic Patients With Chronic Kidney Disease Not on Dialysis: Phase 3 Randomized Trial.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2016 Dec; 20(6):588-597. doi:
10.1111/1744-9987.12461. [PMID: 27896908] - Jürgen Floege. Phosphate binders in chronic kidney disease: a systematic review of recent data.
Journal of nephrology.
2016 Jun; 29(3):329-340. doi:
10.1007/s40620-016-0266-9. [PMID: 26800972] - Keiichi Taniguchi, Hirotoshi Kakuta. Bixalomer, a novel phosphate binder with a small swelling index, improves hyperphosphatemia in chronic kidney disease rat.
European journal of pharmacology.
2015 Nov; 766(?):129-34. doi:
10.1016/j.ejphar.2015.10.001. [PMID: 26452517] - Toru Sanai, Hideo Tada, Takashi Ono, Toma Fukumitsu. Phosphate binders and metabolic acidosis in patients undergoing maintenance hemodialysis—sevelamer hydrochloride, calcium carbonate, and bixalomer.
Hemodialysis international. International Symposium on Home Hemodialysis.
2015 Jan; 19(1):54-9. doi:
10.1111/hdi.12188. [PMID: 24980286] - Tadao Akizawa, Hideki Origasa, Chisato Kameoka, Yuichiro Kaneko, Hiroyuki Kanoh. Dose-finding study of bixalomer in patients with chronic kidney disease on hemodialysis with hyperphosphatemia: a double-blind, randomized, placebo-controlled and sevelamer hydrochloride-controlled open-label, parallel group study.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):24-32. doi:
10.1111/1744-9987.12202. [PMID: 24975892] - Kazunori Furukawa, Tomoyoshi Ikawa, Sayuri Yokoi, Shuhei Yokouchi, Kieko Kato, Miki Ueno, Junichiro Takahashi. Effects of switching from sevelamer hydrochloride to bixalomer on laboratory parameters in hemodialysis patients.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):2-7. doi:
10.1111/1744-9987.12227. [PMID: 24975888] - Hideaki Shima, Ryojiro Makino, Kenichiro Hata, Akihiko Ban, Kiyoaki Funao, Syouzou Sugita, Yutaka Furumitsu, Keisuke Inoue, Mitsuru Yoshimoto, Mikio Okamura. Clinical experiences of bixalomer usage at our hospital.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):13-8. doi:
10.1111/1744-9987.12203. [PMID: 24975890] - Shikou Gen, Takaya Sasaki, Kanako Saito, Kanako Nobe, Yuka Nodaira, Naofumi Ikeda. Clinical effects of the new phosphorus binder, bixalomer in hemodialysis patients switched from sevelamer hydrochloride.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):8-12. doi:
10.1111/1744-9987.12228. [PMID: 24975889] - Kae Ito, Akiko Takeshima, Kanji Shishido, Mikio Wakasa, Chiaki Kumata, Kantaro Matsuzaka, Yutaka Nakajima, Hiroaki Ogata. Treatment of hyperphosphatemia with bixalomer in Japanese patients on long-term hemodialysis with gastrointestinal symptoms.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):19-23. doi:
10.1111/1744-9987.12229. [PMID: 24975891] - Takashi Akiba. Preface.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Jun; 18 Suppl 2(?):1. doi:
10.1111/1744-9987.12231. [PMID: 24975887] - Tadao Akizawa, Hideki Origasa, Chisato Kameoka, Yuichiro Kaneko, Shigenori Kawasaki. Randomized controlled trial of bixalomer versus sevelamer hydrochloride in hemodialysis patients with hyperphosphatemia.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2014 Apr; 18(2):122-31. doi:
10.1111/1744-9987.12068. [PMID: 24720402] - Tadao Akizawa, Chisato Kameoka, Yuichiro Kaneko, Shigenori Kawasaki. Long-term treatment of hyperphosphatemia with bixalomer in Japanese hemodialysis patients.
Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy.
2013 Dec; 17(6):612-9. doi:
10.1111/1744-9987.12023. [PMID: 24330556]