Ecadotril (BioDeep_00000672140)
代谢物信息卡片
Ecadotril
化学式: C21H23NO4S (385.13477180000007)
中文名称: 依卡曲尔
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(=O)SCC(CC1=CC=CC=C1)C(=O)NCC(=O)OCC2=CC=CC=C2
InChI: InChI=1S/C21H23NO4S/c1-16(23)27-15-19(12-17-8-4-2-5-9-17)21(25)22-13-20(24)26-14-18-10-6-3-7-11-18/h2-11,19H,12-15H2,1H3,(H,22,25)/t19-/m1/s1
描述信息
D005765 - Gastrointestinal Agents > D000930 - Antidiarrheals
D004791 - Enzyme Inhibitors > D011480 - Protease Inhibitors
C471 - Enzyme Inhibitor > C783 - Protease Inhibitor
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Lan Li, Chenlin Shen, Lian Tang, Yanxia Yu, Qin Zhou, Xiaohui Huang, Sudong Xue. Determination of thiorphan, a racecadotril metabolite, in human plasma by LC-MS/MS and its application to a bioequivalence study in Chinese subjects
.
International journal of clinical pharmacology and therapeutics.
2020 Jul; 58(7):408-414. doi:
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The Journal of pharmacology and experimental therapeutics.
2016 May; 357(2):423-31. doi:
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Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver.
2011 Sep; 43(9):707-13. doi:
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2011 Jun; 43(7):489-93. doi:
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2010 Apr; 42(4):261-7. doi:
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Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.
2008 Jan; 861(1):130-5. doi:
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2007 Jun; 852(1-2):101-7. doi:
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The Journal of pharmacology and experimental therapeutics.
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2004 Jun; 309(3):1141-7. doi:
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Digestive diseases and sciences.
2003 Feb; 48(2):239-50. doi:
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The New England journal of medicine.
2000 Aug; 343(7):463-7. doi:
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2000 Jul; 18(7):927-33. doi:
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The Journal of pharmacology and experimental therapeutics.
2000 Jun; 293(3):989-95. doi:
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American journal of veterinary research.
2000 Apr; 61(4):425-9. doi:
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American journal of veterinary research.
2000 Mar; 61(3):333-8. doi:
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American heart journal.
1999 Dec; 138(6 Pt 1):1140-8. doi:
10.1016/s0002-8703(99)70081-5. [PMID: 10577446] - A M Duncan, G M James, F Anastasopoulos, A Kladis, T A Briscoe, D J Campbell. Interaction between neutral endopeptidase and angiotensin converting enzyme inhibition in rats with myocardial infarction: effects on cardiac hypertrophy and angiotensin and bradykinin peptide levels.
The Journal of pharmacology and experimental therapeutics.
1999 Apr; 289(1):295-303. doi:
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British journal of pharmacology.
1999 Feb; 126(3):613-20. doi:
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The Canadian journal of cardiology.
1998 Jan; 14(1):63-8. doi:
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European journal of gastroenterology & hepatology.
1997 Sep; 9(9):887-91. doi:
10.1097/00042737-199709000-00012. [PMID: 9355788] - J P Stasch, C Hirth-Dietrich, D Ganten, M Wegner. Renal and antihypertensive effects of neutral endopeptidase inhibition in transgenic rats with an extra renin gene.
American journal of hypertension.
1996 Aug; 9(8):795-802. doi:
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European journal of gastroenterology & hepatology.
1996 May; 8(5):485-9. doi:
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1995 Dec; 38(26):5023-30. doi:
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The American journal of physiology.
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1991 Oct; 84(10):1465-71. doi:
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