(-)-alpinetin (BioDeep_00000671501)
代谢物信息卡片
7-Hydroxy-5-methoxy-2-phenylchroman-4-one
化学式: C16H14O4 (270.0892044)
中文名称: 山姜素
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=CC(=CC2=C1C(=O)CC(O2)C3=CC=CC=C3)O
InChI: InChI=1S/C16H14O4/c1-19-14-7-11(17)8-15-16(14)12(18)9-13(20-15)10-5-3-2-4-6-10/h2-8,13,17H,9H2,1H3
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Yelin Kang, Bong-Gyu Kim, Sunghoon Kim, Youngshim Lee, Youngdae Yoon. Inhibitory potential of flavonoids on PtdIns(3,4,5)P3 binding with the phosphoinositide-dependent kinase 1 pleckstrin homology domain.
Bioorganic & medicinal chemistry letters.
2017 02; 27(3):420-426. doi:
10.1016/j.bmcl.2016.12.051. [PMID: 28049590] - Wenhui Pan, Kanglun Liu, Yifu Guan, Ghee Teng Tan, Nguyen Van Hung, Nguyen Manh Cuong, D Doel Soejarto, John M Pezzuto, Harry H S Fong, Hongjie Zhang. Bioactive compounds from Vitex leptobotrys.
Journal of natural products.
2014 Mar; 77(3):663-7. doi:
10.1021/np400779v. [PMID: 24404757] - Bo Tang, Jian Du, Jingwen Wang, Guang Tan, Zhenming Gao, Zhongyu Wang, Liming Wang. Alpinetin suppresses proliferation of human hepatoma cells by the activation of MKK7 and elevates sensitization to cis-diammined dichloridoplatium.
Oncology reports.
2012 Apr; 27(4):1090-6. doi:
10.3892/or.2011.1580. [PMID: 22159816] - Mee-Young Lee, Chang-Seob Seo, Jin-Ah Lee, In-Sik Shin, Su-Jeong Kim, HeyKyung Ha, Hyeun-Kyoo Shin. Alpinia katsumadai H(AYATA) seed extract inhibit LPS-induced inflammation by induction of heme oxygenase-1 in RAW264.7 cells.
Inflammation.
2012 Apr; 35(2):746-57. doi:
10.1007/s10753-011-9370-0. [PMID: 21830094] - Jian Du, Bo Tang, Jingwen Wang, Hongtao Sui, Xueli Jin, Liming Wang, Zhongyu Wang. Antiproliferative effect of alpinetin in BxPC-3 pancreatic cancer cells.
International journal of molecular medicine.
2012 Apr; 29(4):607-12. doi:
10.3892/ijmm.2012.884. [PMID: 22246103] - Ahmed Belatik, Surat Hotchandani, Robert Carpentier, Heidar-Ali Tajmir-Riahi. Locating the binding sites of Pb(II) ion with human and bovine serum albumins.
PloS one.
2012; 7(5):e36723. doi:
10.1371/journal.pone.0036723. [PMID: 22574219] - Meixia Huo, Na Chen, Gefu Chi, Xue Yuan, Shuang Guan, Hongyu Li, Weiting Zhong, Weixiao Guo, Lanan Wassy Soromou, Ruijie Gao, Hongsheng Ouyang, Xuming Deng, Haihua Feng. Traditional medicine alpinetin inhibits the inflammatory response in Raw 264.7 cells and mouse models.
International immunopharmacology.
2012 Jan; 12(1):241-8. doi:
10.1016/j.intimp.2011.11.017. [PMID: 22178196] - Maidul Hossain, Asma Yasmeen Khan, Gopinatha Suresh Kumar. Interaction of the anticancer plant alkaloid sanguinarine with bovine serum albumin.
PloS one.
2011 Apr; 6(4):e18333. doi:
10.1371/journal.pone.0018333. [PMID: 21494677] - Sri Nurestri Abdul Malek, Chung Weng Phang, Halijah Ibrahim, Abdul Wahab Norhanom, Kae Shin Sim. Phytochemical and cytotoxic investigations of Alpinia mutica rhizomes.
Molecules (Basel, Switzerland).
2011 Jan; 16(1):583-9. doi:
10.3390/molecules16010583. [PMID: 21240148] - Supriya Agnihotri, S Wakode. Antimicrobial activity of essential oil and various extracts of fruits of greater cardamom.
Indian journal of pharmaceutical sciences.
2010 Sep; 72(5):657-9. doi:
10.4103/0250-474x.78542. [PMID: 21695005] - Guowen Zhang, Nan Zhao, Xing Hu, Jiao Tian. Interaction of alpinetin with bovine serum albumin: Probing of the mechanism and binding site by spectroscopic methods.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy.
2010 Aug; 76(3-4):410-7. doi:
10.1016/j.saa.2010.04.009. [PMID: 20427226] - Yongnian Ni, Shuangshuang Wang, Serge Kokot. Spectrometric study of the interaction between alpinetin and bovine serum albumin using chemometrics approaches.
Analytica chimica acta.
2010 Mar; 663(2):139-46. doi:
10.1016/j.aca.2010.01.053. [PMID: 20206002] - Wachirasak Wangkangwan, Saipin Boonkerd, Warinthorn Chavasiri, Kasama Sukapirom, Kovit Pattanapanyasat, Ngampong Kongkathip, Tokichi Miyakawa, Chulee Yompakdee. Pinostrobin from Boesenbergia pandurata is an inhibitor of Ca2+-signal-mediated cell-cycle regulation in the yeast Saccharomyces cerevisiae.
Bioscience, biotechnology, and biochemistry.
2009 Jul; 73(7):1679-82. doi:
10.1271/bbb.90114. [PMID: 19584530] - Xiu-Qin Wang, Xiao-Jiang Yang, Jiao-She Li. [Studies on chemical constituents of alpinia katsumadai].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2008 Jun; 31(6):853-5. doi:
". [PMID: 18998568] - Guo-Wen Zhang, An-Ping Wang, Ting Jiang. [Studies on the interaction between alpinetin and human serum albumin by fluorescence spectroscopy].
Guang pu xue yu guang pu fen xi = Guang pu.
2008 Apr; 28(4):908-12. doi:
NULL. [PMID: 18619327] - João Paulo V Leite, Alaíde B Oliveira, Júlio A Lombardi, José Dias S Filho, Egler Chiari. Trypanocidal activity of triterpenes from Arrabidaea triplinervia and derivatives.
Biological & pharmaceutical bulletin.
2006 Nov; 29(11):2307-9. doi:
10.1248/bpb.29.2307. [PMID: 17077535] - Wenying He, Ying Li, Chunxia Xue, Zhide Hu, Xingguo Chen, Fenling Sheng. Effect of Chinese medicine alpinetin on the structure of human serum albumin.
Bioorganic & medicinal chemistry.
2005 Mar; 13(5):1837-45. doi:
10.1016/j.bmc.2004.11.038. [PMID: 15698801] - Ibrahim Jantan, Mazura Pisar, Hasnah Mohd Sirat, Norazah Basar, Shajarahtunnur Jamil, Rasadah Mat Ali, Juriyati Jalil. Inhibitory effects of compounds from Zingiberaceae species on platelet activating factor receptor binding.
Phytotherapy research : PTR.
2004 Dec; 18(12):1005-7. doi:
10.1002/ptr.1608. [PMID: 15742349] - Yu-Juan Li, Guan-Hua Du. Effects of alpinetin on rat vascular smooth muscle cells.
Journal of Asian natural products research.
2004 Jun; 6(2):87-92. doi:
10.1080/1028602031000135558. [PMID: 15008454] - R W Jiang, Z D He, P P But, Y M Chan, S C Ma, T C Mak. A novel 1:1 complex of potassium mikanin-3-O-sulfate with methanol.
Chemical & pharmaceutical bulletin.
2001 Sep; 49(9):1166-9. doi:
10.1248/cpb.49.1166. [PMID: 11558604]