benzphetamine hydrochloride (BioDeep_00000670804)

   


代谢物信息卡片


benzyl-methyl-[(2S)-1-phenylpropan-2-yl]azanium;chloride

化学式: C17H22ClN (275.14406820000005)
中文名称: 盐酸苄非他明
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CC1=CC=CC=C1)N(C)CC2=CC=CC=C2.Cl
InChI: /m0./s1

描述信息

D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018759 - Adrenergic Uptake Inhibitors
D018377 - Neurotransmitter Agents > D014179 - Neurotransmitter Uptake Inhibitors > D018765 - Dopamine Uptake Inhibitors
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents > D013566 - Sympathomimetics
D002491 - Central Nervous System Agents > D000697 - Central Nervous System Stimulants
C78272 - Agent Affecting Nervous System > C47795 - CNS Stimulant
D018377 - Neurotransmitter Agents > D018663 - Adrenergic Agents
C78272 - Agent Affecting Nervous System > C29728 - Anorexiant
D018377 - Neurotransmitter Agents > D015259 - Dopamine Agents
D049990 - Membrane Transport Modulators

同义名列表

2 个代谢物同义名

benzphetamine hydrochloride; benzyl-methyl-[(2S)-1-phenylpropan-2-yl]azanium;chloride



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Matthew L Banks, Rodney W Snyder, Timothy R Fennell, S Stevens Negus. Role of d-amphetamine and d-methamphetamine as active metabolites of benzphetamine: Evidence from drug discrimination and pharmacokinetic studies in male rhesus monkeys. Pharmacology, biochemistry, and behavior. 2017 05; 156(?):30-38. doi: 10.1016/j.pbb.2017.03.008. [PMID: 28373066]
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  • Emel Arinç, Haydar Celik, Haydar Lelik. Biochemical characteristics of purified beef liver NADPH-cytochrome P450 reductase. Journal of biochemical and molecular toxicology. 2002; 16(6):286-97. doi: 10.1002/jbt.10054. [PMID: 12481304]
  • M Sato, T Mitsui, H Nagase. Analysis of benzphetamine and its metabolites in rat urine by liquid chromatography-electrospray ionization mass spectrometry. Journal of chromatography. B, Biomedical sciences and applications. 2001 Feb; 751(2):277-89. doi: 10.1016/s0378-4347(00)00482-5. [PMID: 11236083]
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  • F Musshoff. Illegal or legitimate use? Precursor compounds to amphetamine and methamphetamine. Drug metabolism reviews. 2000 Feb; 32(1):15-44. doi: 10.1081/dmr-100100562. [PMID: 10711406]
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  • A Fujinami, T Miyazawa, Y Kobayashi. Development of a method for the quantitation of benzphetamine metabolites in human urine by high-performance liquid chromatography. Annals of clinical biochemistry. 1998 Nov; 35 ( Pt 6)(?):775-9. doi: 10.1177/000456329803500611. [PMID: 9838992]
  • A Fujinami, T Miyazawa, N Tagawa, Y Kobayashi. Simultaneous analysis of benzphetamine and its metabolites, and quantitation of urinary p-hydroxy-N-benzylamphetamine by micellar electrokinetic chromatography. Biological & pharmaceutical bulletin. 1998 Nov; 21(11):1207-10. doi: 10.1248/bpb.21.1207. [PMID: 9853414]
  • J T Cody, S Valtier. Detection of amphetamine and methamphetamine following administration of benzphetamine. Journal of analytical toxicology. 1998 Jul; 22(4):299-309. doi: 10.1093/jat/22.4.299. [PMID: 9681333]
  • P M Shaw, N A Hosea, D V Thompson, J M Lenius, F P Guengerich. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5. Archives of biochemistry and biophysics. 1997 Dec; 348(1):107-15. doi: 10.1006/abbi.1997.0378. [PMID: 9390180]
  • R Kikura, Y Nakahara. Hair analysis for drugs of abuse. XI. Disposition of benzphetamine and its metabolites into hair and comparison of benzphetamine use and methamphetamine use by hair analysis. Biological & pharmaceutical bulletin. 1995 Dec; 18(12):1694-9. doi: 10.1248/bpb.18.1694. [PMID: 8787790]
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  • M J Choi, J Choi, J Park, S A Eremin. Localization of the epitope in methamphetamine and its antibody use for the detection of methamphetamine and benzphetamine by polarization fluoroimmunoassay. Journal of immunoassay. 1995 Aug; 16(3):263-78. doi: 10.1080/15321819508013562. [PMID: 7593649]
  • J B Watkins, J W LaFollette, R A Sanders. Biotransformation in Egyptian spiny mouse Acomys cahirinus. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. 1995 Jan; 110(1):101-7. doi: 10.1016/0742-8413(94)00104-i. [PMID: 7749597]
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