Xenopsin (XP) (BioDeep_00000669863)
代谢物信息卡片
化学式: C47H73N13O10 (979.5603078)
中文名称: 爪蟾降压肽
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC(C)C(C(=O)NC(CC(C)C)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)NC(=O)C3CCCN3C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)CNC(=O)C4CCC(=O)N4
InChI: InChI=1S/C47H73N13O10/c1-5-27(4)39(44(67)58-35(46(69)70)22-26(2)3)59-42(65)34(23-28-24-52-30-13-7-6-12-29(28)30)57-43(66)36-16-11-21-60(36)45(68)33(15-10-20-51-47(49)50)56-41(64)31(14-8-9-19-48)55-38(62)25-53-40(63)32-17-18-37(61)54-32/h6-7,12-13,24,26-27,31-36,39,52H,5,8-11,14-23,25,48H2,1-4H3,(H,53,63)(H,54,61)(H,55,62)(H,56,64)(H,57,66)(H,58,67)(H,59,65)(H,69,70)(H4,49,50,51)
描述信息
Xenopsin, a neurotensin-like octapeptide from Xenopus laevis skin[1]. Xenopsin is an inhibitor of Tetragastrin stimulated gastric acid secretion[2].
同义名列表
相关代谢途径
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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INOH(0)
PlantCyc(0)
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PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Kate A Rawlinson, Francois Lapraz, Edward R Ballister, Mark Terasaki, Jessica Rodgers, Richard J McDowell, Johannes Girstmair, Katharine E Criswell, Miklos Boldogkoi, Fraser Simpson, David Goulding, Claire Cormie, Brian Hall, Robert J Lucas, Maximilian J Telford. Extraocular, rod-like photoreceptors in a flatworm express xenopsin photopigment.
eLife.
2019 10; 8(?):. doi:
10.7554/elife.45465. [PMID: 31635694] - Muzaffer Temur, Pelin Özün Özbay, Saliha Aksun, Özgür Yilmaz, Tayfur Çift, Sibel Üstünel, Mehmet Calan. Elevated circulating levels of xenopsin-related peptide-1 are associated with polycystic ovary syndrome.
Archives of gynecology and obstetrics.
2017 Oct; 296(4):841-846. doi:
10.1007/s00404-017-4493-7. [PMID: 28831586] - Dinesh Srinivasan, Milena Mechkarska, Yasser H A Abdel-Wahab, Peter R Flatt, J Michael Conlon. Caerulein precursor fragment (CPF) peptides from the skin secretions of Xenopus laevis and Silurana epitropicalis are potent insulin-releasing agents.
Biochimie.
2013 Feb; 95(2):429-35. doi:
10.1016/j.biochi.2012.10.026. [PMID: 23142129] - Osama K Zahid, Milena Mechkarska, Opeolu O Ojo, Yasser H A Abdel-Wahab, Peter R Flatt, Mohammed A Meetani, J Michael Conlon. Caerulein-and xenopsin-related peptides with insulin-releasing activities from skin secretions of the clawed frogs, Xenopus borealis and Xenopus amieti (Pipidae).
General and comparative endocrinology.
2011 Jun; 172(2):314-20. doi:
10.1016/j.ygcen.2011.03.022. [PMID: 21458457] - R E Carraway, S P Mitra, D E Cochrane. Pro-xenopsin(s) in vesicles of mammalian brain, liver, stomach and intestine is apparently released into blood and cerebral spinal fluid.
Regulatory peptides.
2000 Nov; 95(1-3):115-24. doi:
10.1016/s0167-0115(00)00163-4. [PMID: 11062341] - G E Feurle, G Hamscher, R Kusiek, H E Meyer, J W Metzger. Identification of xenin, a xenopsin-related peptide, in the human gastric mucosa and its effect on exocrine pancreatic secretion.
The Journal of biological chemistry.
1992 Nov; 267(31):22305-9. doi:
10.1016/s0021-9258(18)41670-5. [PMID: 1429581] - D E Cochrane, R E Carraway, W Boucher. Generation of xenopsin-related peptides from tissue precursors by media conditioned by endotoxin-stimulated rat peritoneal macrophages.
Inflammation.
1991 Oct; 15(5):381-90. doi:
10.1007/bf00917354. [PMID: 1757125] - C Shaw, F Stöckmann, J M Conlon. Xenopsin- and neurotensin-like peptides in gastric juice from patients with duodenal ulcers.
European journal of clinical investigation.
1987 Aug; 17(4):306-12. doi:
10.1111/j.1365-2362.1987.tb02192.x. [PMID: 3117567] - M H Mogard, R Kobayashi, C F Chen, T D Lee, J R Reeve, J E Shively, J H Walsh. The amino acid sequence of kinetensin, a novel peptide isolated from pepsin-treated human plasma: homology with human serum albumin, neurotensin and angiotensin.
Biochemical and biophysical research communications.
1986 May; 136(3):983-8. doi:
10.1016/0006-291x(86)90429-8. [PMID: 3087352] - M J Zinner, F Kasher, I M Modlin, B M Jaffe. Effect of xenopsin on blood flow, hormone release, and acid secretion.
The American journal of physiology.
1982 Sep; 243(3):G195-9. doi:
10.1152/ajpgi.1982.243.3.g195. [PMID: 7114262] - K Kawanishi, A Goto, T Ishida, K Kawamura, Y Nishina, S Machida, S Yamamoto, T Ofuji. The effects of xenopsin of endocrine pancreas and gastric antrum in dogs.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme.
1978 Jul; 10(4):283-6. doi:
10.1055/s-0028-1093415. [PMID: 355074] - R Tanaka, K Shima, Y Kumahara, T Matsuyama, S Tarui, N Sawazaki. [Glucagon-releasing activity of xenopsin, neurotensin and substance P in the perfused rat pancreas (author's transl)].
Nihon Naibunpi Gakkai zasshi.
1978 Jan; 54(1):23-8. doi:
10.1507/endocrine1927.54.1_23. [PMID: 631379]