Emideltide;Delta Sleep Inducing Peptide (BioDeep_00000669846)

   


代谢物信息卡片


Delta-Sleep Inducing Peptide trifluoroacetate salt

化学式: C35H48N10O15 (848.3300458)
中文名称: 依米地肽
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C(=O)NCC(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(C)C(=O)NC(CO)C(=O)NCC(=O)NC(CCC(=O)O)C(=O)O)NC(=O)C(CC1=CNC2=CC=CC=C21)N
InChI: InChI=1S/C35H48N10O15/c1-16(41-32(56)20(36)9-18-11-37-21-6-4-3-5-19(18)21)30(54)39-12-25(47)38-13-26(48)44-23(10-29(52)53)34(58)42-17(2)31(55)45-24(15-46)33(57)40-14-27(49)43-22(35(59)60)7-8-28(50)51/h3-6,11,16-17,20,22-24,37,46H,7-10,12-15,36H2,1-2H3,(H,38,47)(H,39,54)(H,40,57)(H,41,56)(H,42,58)(H,43,49)(H,44,48)(H,45,55)(H,50,51)(H,52,53)(H,59,60)

描述信息

D018377 - Neurotransmitter Agents

同义名列表

2 个代谢物同义名

Delta-Sleep Inducing Peptide trifluoroacetate salt; Emideltide;Delta Sleep Inducing Peptide



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Xin-Guo Zhang, Wen-Na Wang, Chun-Sheng Zhang, Kun Li, Guo-Di Ma, Jian-Yong Li. Expression and Purification of Delta Sleep-Inducing Peptide Fused with Protein Transduction Domain and Human Serum Albumin in Pichia pastoris. Protein and peptide letters. 2017; 24(7):668-675. doi: 10.2174/0929866524666170426113022. [PMID: 28462721]
  • I I Bobyntsev, A A Kryukov, A E Belykh, V T Dudka. Effect of Delta Sleep-Inducing Peptide on Functional State of Hepatocytes in Rats During Restraint Stress. Bulletin of experimental biology and medicine. 2016 Feb; 160(4):421-4. doi: 10.1007/s10517-016-3186-8. [PMID: 26902351]
  • A E Belykh, I I Bobyntsev, A A Kryukov, V T Dudka. [THE INFLUENCE OF DELTA SLEEP-INDUCING PEPTIDE ON FUNCTIONAL STATE OF RATS HEPATOCYTES IN FOOT-SHOCK STRESS]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2015 Jun; 101(6):700-7. doi: NULL. [PMID: 26470489]
  • I I Mikhaleva, V T Ivanov, L V Onoprienko, I A Prudchenko, L D Chikin, R I Yakubovskaya, E R Nemtsova, O A Bezborodova. [Antioxidative and detoxifying effects of analogues of delta-sleep inducing peptide (DSIP)]. Bioorganicheskaia khimiia. 2014 Jan; 40(1):3-11. doi: 10.1134/s1068162014010087. [PMID: 25898718]
  • I I Mikhaleva, V T Ivanov, V B Voĭtenkov, E M Vechkanov, T I Bondarenko. [Olygopeptide KND as a putative endogenous prototype of delta sleep inducing peptide (DSIP). Comparative study of biological properties]. Bioorganicheskaia khimiia. 2013 May; 39(3):277-84. doi: 10.1134/s1068162013030096. [PMID: 24397026]
  • T I Bondarenko, E A Maĭboroda, I I Mikhaleva, I A Prudchenko. [Metabolic effects of delta-sleep inducing peptide during physiological aging of the organism]. Eksperimental'naia i klinicheskaia farmakologiia. 2013; 76(9):22-6. doi: NULL. [PMID: 24432565]
  • T I Bondarenko, E A Maĭboroda, I I Mikhaleva, I A Prudchenko. [Mechanism of delta-sleep inducing peptide geroprotective activity]. Advances in gerontology = Uspekhi gerontologii. 2011; 24(1):80-92. doi: NULL. [PMID: 21809625]
  • E A Ivanova, E V Koplik. [Changes in duodenal lymphoid structures in rats with various behavioral activity, caused by delta sleep-inducing peptide and following acute emotional stress]. Morfologiia (Saint Petersburg, Russia). 2010; 137(2):38-43. doi: NULL. [PMID: 20572393]
  • Lena Brundin, Maria Björkqvist, Asa Petersén, Lil Träskman-Bendz. Reduced orexin levels in the cerebrospinal fluid of suicidal patients with major depressive disorder. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. 2007 Sep; 17(9):573-9. doi: 10.1016/j.euroneuro.2007.01.005. [PMID: 17346943]
  • I I Mikhaleva, G T Rikhireva, I A Prudchenko, I N Golubev. [Interaction of delta sleep-inducing peptide and its analogues with cellular membranes: a structure-function analysis]. Bioorganicheskaia khimiia. 2006 Mar; 32(2):176-82. doi: 10.1134/s1068162006020087. [PMID: 16637289]
  • E V Koplik, Yu A Gryzunov, G E Dobretsov. Blood albumin in the mechanisms of individual resistance of rats to emotional stress. Neuroscience and behavioral physiology. 2003 Oct; 33(8):827-32. doi: 10.1023/a:1025109717945. [PMID: 14636000]
  • T A Shustanova, T I Bondarenko, N P Miliutina, I I Mikhaleva. [Features of regulating delta sleep-inducing peptide by free radical processes in tissue and erythrocyte membranes in intact animals and under stress]. Uspekhi fiziologicheskikh nauk. 2003 Jan; 34(1):31-44. doi: ". [PMID: 12635477]
  • E V Koplik, Iu A Grysunov, G E Dobretsov. [Blood albumin in mechanisms of individual resistance of rats to emotional stress]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 2002 Jun; 88(6):707-14. doi: NULL. [PMID: 12154567]
  • T I Bondarenko, Iu A Kalmykova, T A Shustanova, I I Mikhaleva. [Pharmacological efficacy of delta sleep-inducing peptide in experimental acute pancreatitis]. Eksperimental'naia i klinicheskaia farmakologiia. 2002 Mar; 65(2):44-8. doi: NULL. [PMID: 12109293]
  • T A Shustanova, T I Bondarenko, N P Milyutina, I I Mikhaleva. Regulation of free radical processes by delta-sleep inducing peptide in rat tissues under cold stress. Biochemistry. Biokhimiia. 2001 Jun; 66(6):632-9. doi: 10.1023/a:1010255230338. [PMID: 11421812]
  • T I Bondarenko, N P Milyutina, T A Shustanova, I I Mikhaleva. The effects of delta sleep-inducing peptide on the intensity of lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress. Neuroscience and behavioral physiology. 2001 Jan; 31(1):83-6. doi: 10.1023/a:1026686516768. [PMID: 11265821]
  • T I Bondarenko, N P Miliutina, T A Shustanova, I I Mikhaleva. [Effect of delta sleep-inducing peptide on lipid peroxidation and xanthine oxidase activity in rat tissues during cold stress]. Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova. 1999 Aug; 85(8):1080-4. doi: ". [PMID: 10643602]
  • A V Lysenko, D V Alperovich, N I Uskova, A M Mendzheritsky. Metabolic features of the adaptive effect of delta-sleep inducing peptide and piracetam under hyperoxic conditions. Biochemistry. Biokhimiia. 1999 Jun; 64(6):652-7. doi: ". [PMID: 10395980]
  • G T Rikhireva, I N Golubev, S A Kopylovskiĭ, I A Prudchenko, I I Mikhaleva. [Interaction of delta-sleep-inducing peptide with cell membranes in vitro]. Bioorganicheskaia khimiia. 1999 May; 25(5):334-40. doi: ". [PMID: 10495890]
  • T I Bondarenko, N P Miliutina, I I Mikhaleva, N V Noskova. [Membrane-stabilizing effect of delta sleep-inducing peptide during stress]. Biulleten' eksperimental'noi biologii i meditsiny. 1998 Sep; 126(9):325-7. doi: ". [PMID: 9805623]
  • A Westrin, R Ekman, L Träskman-Bendz. High delta sleep-inducing peptide-like immunoreactivity in plasma in suicidal patients with major depressive disorder. Biological psychiatry. 1998 May; 43(10):734-9. doi: 10.1016/s0006-3223(97)00254-0. [PMID: 9606527]
  • A Westrin, G Engstöm, R Ekman, L Träskman-Bendz. Correlations between plasma-neuropeptides and temperament dimensions differ between suicidal patients and healthy controls. Journal of affective disorders. 1998 Apr; 49(1):45-54. doi: 10.1016/s0165-0327(97)00197-3. [PMID: 9574859]
  • E Polverini, R Casadio, P Neyroz, L Masotti. Conformational changes of neuromedin B and delta sleep-inducing peptide induced by their interaction with lipid membranes as revealed by spectroscopic techniques and molecular dynamics simulation. Archives of biochemistry and biophysics. 1998 Jan; 349(2):225-35. doi: 10.1006/abbi.1997.0395. [PMID: 9448709]
  • T G Sazontova, N E Golantsova, S N Kolmykova, M I Arkhangel'skaia, I L Kosharskaia, Iu V Arkhipenko. [Effect of delta sleep-inducing peptide on the status of the calcium transport system of the sarcoplasmic reticulum and activity of antioxidant defense enzymes in the myocardium]. Biulleten' eksperimental'noi biologii i meditsiny. 1996 Mar; 121(3):248-51. doi: ". [PMID: 8688518]
  • N I Uskova, A V Lysenko, A M Mendzheritskii. [Comparative investigation of anticonvulsive effects of putrescine and structural analogues of delta-sleep-inducing peptide]. Vestnik Rossiiskoi akademii meditsinskikh nauk. 1996; ?(9):27-30. doi: NULL. [PMID: 8983406]
  • K V Sudakov, J P Coghlan, A V Kotov, R M Salieva, Polyntsev YuV, E V Koplik. Delta-sleep-inducing peptide sequels in the mechanisms of resistance to emotional stress. Annals of the New York Academy of Sciences. 1995 Dec; 771(?):240-51. doi: 10.1111/j.1749-6632.1995.tb44685.x. [PMID: 8597403]
  • K V Sudakov, J P Coghlan, A V Kotov, R M Salieva, Iu V Polyntsev, E V Koplik. [Changes in the content of substance P, beta-endorphin and corticosterone in the hypothalamus and blood of rats with emotional stress after the administration of the delta sleep-inducing peptide]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. 1995 Sep; 45(5):982-9. doi: NULL. [PMID: 8560945]
  • A M Mendzheritskiĭ, A V Lysenko, N I Uskova. [Proteolytic processes in the rat brain and serum in hypokinesia and the adaptive effect of delta-sleep inducing peptide]. Biokhimiia (Moscow, Russia). 1995 Apr; 60(4):585-92. doi: NULL. [PMID: 7779981]
  • E Seifritz, M J Müller, G A Schönenberger, L Trachsel, U Hemmeter, M Hatzinger, A Ernst, P Moore, E Holsboer-Trachsler. Human plasma DSIP decreases at the initiation of sleep at different circadian times. Peptides. 1995; 16(8):1475-81. doi: 10.1016/0196-9781(95)02027-6. [PMID: 8745061]
  • A N Vgontzas, T C Friedman, G P Chrousos, E O Bixler, A Vela-Bueno, A Kales. Delta sleep-inducing peptide in normal humans and in patients with sleep apnea and narcolepsy. Peptides. 1995; 16(6):1153-6. doi: 10.1016/0196-9781(95)00092-x. [PMID: 8532601]
  • T C Friedman, D García-Borreguero, D Hardwick, C N Akuete, J L Doppman, L D Dorn, C N Barker, J A Yanovski, G P Chrousos. Decreased delta-sleep and plasma delta-sleep-inducing peptide in patients with Cushing syndrome. Neuroendocrinology. 1994 Dec; 60(6):626-34. doi: 10.1159/000126806. [PMID: 7700506]
  • P Schulz, S Lustenberger, R Degli Agosti, R W Rivest. Plasma concentration of nine hormones and neurotransmitters during usual activities or constant bed rest for 34 H. Chronobiology international. 1994 Dec; 11(6):367-80. doi: 10.3109/07420529409057254. [PMID: 7895296]
  • T C Friedman, D Garcia-Borreguero, D Hardwick, C N Akuete, M K Stambuk, L D Dorn, M N Starkman, Y P Loh, G P Chrousos. Diurnal rhythm of plasma delta-sleep-inducing peptide in humans: evidence for positive correlation with body temperature and negative correlation with rapid eye movement and slow wave sleep. The Journal of clinical endocrinology and metabolism. 1994 May; 78(5):1085-9. doi: 10.1210/jcem.78.5.8175965. [PMID: 8175965]
  • P Chiodera, R Volpi, L Capretti, G Giacalone, G Caffarri, C Davoli, E Nigro, V Coiro. Different effects of delta-sleep-inducing peptide on arginine-vasopressin and ACTH secretion in normal men. Hormone research. 1994; 42(6):267-72. doi: 10.1159/000184207. [PMID: 7698722]
  • R Sillard, P Schulz-Knappe, P Vogel, M Raida, K W Bensch, W G Forssmann, V Mutt. A novel 77-residue peptide from porcine brain contains a leucine-zipper motif and is recognized by an antiserum to delta-sleep-inducing peptide. European journal of biochemistry. 1993 Sep; 216(2):429-36. doi: 10.1111/j.1432-1033.1993.tb18160.x. [PMID: 8375381]
  • G T Rikhireva, M G Makletsova, A M Mendzherkitskiĭ, L S Vartanian, S M Gurevich, E L Lozovskaia, S A Kopylovskiĭ, A V Rylova, I A Prudchenko, I I Mikhaleva. [Changes in the intensity of free-radical reactions in the organs of rats under hypokinetic stress and with protection by the delta sleep-inducing peptide and its tyrosine-containing analog]. Izvestiia Akademii nauk. Seriia biologicheskaia. 1993 Mar; ?(2):243-56. doi: ". [PMID: 8471976]
  • M Giusti, A Carraro, E Porcella, S Valenti, D Nicora, P Sessarego, G Giordano. Delta sleep-inducing peptide administration does not influence growth hormone and prolactin secretion in normal women. Psychoneuroendocrinology. 1993; 18(1):79-84. doi: 10.1016/0306-4530(93)90057-r. [PMID: 8475226]
  • A M Mendzheritskiĭ, A V Lysenko, I I Mikhaleva. [Influence of delta-sleep-inducing peptide on the activity of proteolytic enzymes in the rat brain under hypokinesia]. Ukrainskii biokhimicheskii zhurnal (1978). 1992 Sep; 64(5):37-42. doi: NULL. [PMID: 1462368]
  • S Scholle, G Zwacka, R Ekman, S Glaser. Plasma levels of DSIP in infants in the first year of life and SIDS risk. Regulatory peptides. 1992 Apr; 39(1):29-33. doi: 10.1016/0167-0115(92)90005-f. [PMID: 1579657]
  • M M Cathieni, C H Taban. Microwave-aided binding of gold-protein-ligand (GPL) complexes. Light microscopic observations in the rat brain. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 1992 Mar; 40(3):387-401. doi: 10.1177/40.3.1372631. [PMID: 1372631]
  • J Hegbrant, H Thysell, R Ekman. Erythropoietin treatment and plasma levels of corticotropin-releasing hormone, delta sleep-inducing peptide and opioid peptides in hemodialysis patients. Scandinavian journal of urology and nephrology. 1992; 26(4):393-6. doi: 10.3109/00365599209181232. [PMID: 1337953]
  • J Hegbrant, H Thysell, R Ekman. Elevated plasma levels of opioid peptides and delta sleep-inducing peptide but not of corticotropin-releasing hormone in patients receiving chronic hemodialysis. Blood purification. 1991; 9(4):188-94. doi: 10.1159/000170017. [PMID: 1667974]
  • A Bjartell, F Sundler, R Ekman. Immunoreactive delta sleep-inducing peptide in the rat hypothalamus, pituitary and adrenal gland: effects of adrenalectomy. Hormone research. 1991; 36(1-2):52-62. doi: 10.1159/000182108. [PMID: 1814802]
  • A M Mendzheritskiĭ, M G Makletsova, N I Uskova, I O Choraian, I I Mikhaleva. [Antistressor effect of delta-sleep-inducing peptide in hypokinetic stress]. Ukrainskii biokhimicheskii zhurnal (1978). 1991 Jan; 63(1):34-7. doi: ". [PMID: 1674176]
  • R Iu Iukhananov, V V Rozhanets, I I Mikhaleva, A I Maĭskiĭ. [Analysis of the mechanism of the stress-protective action of delta sleep-inducing peptide]. Biulleten' eksperimental'noi biologii i meditsiny. 1990 Jan; 109(1):46-7. doi: NULL. [PMID: 2159352]
  • A Bjartell, R Ekman, S Bergquist, E Widerlöv. Reduction of immunoreactive ACTH in plasma following intravenous injection of delta sleep-inducing peptide in man. Psychoneuroendocrinology. 1989; 14(5):347-55. doi: 10.1016/0306-4530(89)90004-8. [PMID: 2554357]
  • K P Lesch, E Widerlöv, R Ekman, G Laux, H M Schulte, H Pfüller, H Beckmann. Delta sleep-inducing peptide response to human corticotropin-releasing hormone (CRH) in major depressive disorder. Comparison with CRH-induced corticotropin and cortisol secretion. Biological psychiatry. 1988 Jun; 24(2):162-72. doi: 10.1016/0006-3223(88)90271-5. [PMID: 2839244]
  • K S Iyer, G A Marks, A J Kastin, S M McCann. Evidence for a role of delta sleep-inducing peptide in slow-wave sleep and sleep-related growth hormone release in the rat. Proceedings of the National Academy of Sciences of the United States of America. 1988 May; 85(10):3653-6. doi: 10.1073/pnas.85.10.3653. [PMID: 3368469]
  • Iu P Shmal'ko, I I Mikhaleva. [Antimetastatic effect of the delta-sleep peptide during stress in mice with Lewis' lung carcinoma]. Eksperimental'naia onkologiia. 1988; 10(2):57-60. doi: ". [PMID: 2899023]
  • K S Iyer, S M McCann. Delta sleep inducing peptide (DSIP) stimulates the release of LH but not FSH via a hypothalamic site of action in the rat. Brain research bulletin. 1987 Nov; 19(5):535-8. doi: 10.1016/0361-9230(87)90069-4. [PMID: 3121137]
  • M V Graf, B Saegesser, G A Schoenenberger. Degradation and aggregation of delta sleep-inducing peptide (DSIP) and two analogs in plasma and serum. Peptides. 1987 Jul; 8(4):599-603. doi: 10.1016/0196-9781(87)90031-3. [PMID: 3628078]
  • M A Zviagintseva, I L Kosharskaia, V I Badikov, N N Beskrovnova, L S Ul'ianinskiĭ. [Parasympathetic regulation of cardiac rhythm in delta sleep-inducing peptide deficiency]. Biulleten' eksperimental'noi biologii i meditsiny. 1987 Jul; 104(7):3-5. doi: NULL. [PMID: 3620643]
  • R Ekman, A Bjartell, E Ekblad, F Sundler. Immunoreactive delta sleep-inducing peptide in pituitary adrenocorticotropin/alpha-melanotropin cells and adrenal medullary cells of the pig. Neuroendocrinology. 1987 Apr; 45(4):298-304. doi: 10.1159/000124744. [PMID: 3033539]
  • K S Iyer, S M McCann. Delta sleep-inducing peptide (DSIP) stimulates growth hormone (GH) release in the rat by hypothalamic and pituitary actions. Peptides. 1987 Jan; 8(1):45-8. doi: 10.1016/0196-9781(87)90163-x. [PMID: 3575154]
  • M V Graf, B Saegesser, G A Schoenenberger. Separation of tryptophan from DSIP, a Trp-nonapeptide, by adsorption to aluminum oxide. Analytical biochemistry. 1986 Sep; 157(2):295-9. doi: 10.1016/0003-2697(86)90630-5. [PMID: 3777433]
  • W A Banks, A J Kastin, D H Coy, E Angulo. Entry of DSIP peptides into dog CSF: role of physicochemical and pharmacokinetic parameters. Brain research bulletin. 1986 Aug; 17(2):155-8. doi: 10.1016/0361-9230(86)90111-5. [PMID: 3768731]
  • A A Krichevskaia, T I Bondarenko, E Iu Krupennikova, I I Mikhaleva. [Effect of delta-sleep-peptide on the state of brain membranes during exposure to cold stress]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 1986 Jun; 72(6):843-5. doi: ". [PMID: 3525242]
  • M V Graf, A J Kastin, G A Schoenenberger. Delta sleep-inducing peptide in spontaneously hypertensive rats. Pharmacology, biochemistry, and behavior. 1986 Jun; 24(6):1797-9. doi: 10.1016/0091-3057(86)90524-1. [PMID: 3755534]
  • K Nakagaki, S Ebihara, S Usui, Y Honda, Y Takahashi, N Kato. [Effects of intraventricular injection of anti-DSIP serum on sleep in rats]. Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology. 1986 Jun; 6(2):259-65. doi: NULL. [PMID: 3776352]
  • W A Banks, A J Kastin. Aluminum alters the permeability of the blood-brain barrier to some non-peptides. Neuropharmacology. 1985 May; 24(5):407-12. doi: 10.1016/0028-3908(85)90025-5. [PMID: 4022265]
  • T I Bondarenko, A A Krichevskaia, E Iu Krupennikova, I I Mikhaleva. [Effect of the delta-sleep peptide on erythrocyte membrane function during low-temperature exposure]. Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova. 1985 Mar; 71(3):279-82. doi: NULL. [PMID: 3838950]
  • W A Banks, A J Kastin, J K Selznick. Modulation of immunoactive levels of DSIP and blood-brain permeability by lighting and diurnal rhythm. Journal of neuroscience research. 1985; 14(3):347-55. doi: 10.1002/jnr.490140307. [PMID: 3840534]
  • W A Banks, A J Kastin. The aluminum-induced increase in blood-brain barrier permeability to delta-sleep-inducing peptide occurs throughout the brain and is independent of phosphorus and acetylcholinesterase levels. Psychopharmacology. 1985; 86(1-2):84-9. doi: 10.1007/bf00431689. [PMID: 3927370]
  • A J Kastin, P F Castellanos, A J Fischman, J K Proffitt, M V Graf. Evidence for peptide aggregation. Pharmacology, biochemistry, and behavior. 1984 Dec; 21(6):969-73. doi: 10.1016/s0091-3057(84)80082-9. [PMID: 6151671]
  • A J Fischman, A J Kastin, M V Graf. Circadian variation of DSIP-like material in rat plasma. Life sciences. 1984 Nov; 35(20):2079-84. doi: 10.1016/0024-3205(84)90566-6. [PMID: 6548540]
  • M V Graf, A J Kastin, A J Fischman. DSIP occurs in free form in mammalian plasma, human CSF and urine. Pharmacology, biochemistry, and behavior. 1984 Nov; 21(5):761-6. doi: 10.1016/s0091-3057(84)80016-7. [PMID: 6549071]
  • M V Graf, A J Kastin. Delta sleep-inducing peptide (DSIP)-like material exists in peripheral organs of rats in large dissociable forms. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 1984 Oct; 177(1):197-204. doi: 10.3181/00379727-177-41932. [PMID: 6548030]
  • N Kato, Y Honda, S Ebihara, H Naruse, Y Takahashi. Development of an enzyme immunoassay for delta sleep-inducing peptide (DSIP) and its use in the determination of the metabolic clearance rate of DSIP administered to dogs. Neuroendocrinology. 1984 Jul; 39(1):39-44. doi: 10.1159/000123952. [PMID: 6379493]
  • M V Graf, C A Hunter, A J Kastin. Presence of delta-sleep-inducing peptide-like material in human milk. The Journal of clinical endocrinology and metabolism. 1984 Jul; 59(1):127-32. doi: 10.1210/jcem-59-1-127. [PMID: 6547144]
  • V T Ivanov. [Immunoactive peptides]. Voprosy meditsinskoi khimii. 1984 May; 30(3):23-31. doi: NULL. [PMID: 6206648]
  • G A Schoenenberger. Characterization, properties and multivariate functions of delta-sleep-inducing peptide (DSIP). European neurology. 1984; 23(5):321-45. doi: 10.1159/000115711. [PMID: 6548966]
  • M V Graf, A J Kastin. Delta-sleep-inducing peptide (DSIP): a review. Neuroscience and biobehavioral reviews. 1984; 8(1):83-93. doi: 10.1016/0149-7634(84)90022-8. [PMID: 6145137]
  • W Larbig, W D Gerber, M Kluck, G A Schoenenberger. Therapeutic effects of delta-sleep-inducing peptide (DSIP) in patients with chronic, pronounced pain episodes. A clinical pilot study. European neurology. 1984; 23(5):372-85. doi: 10.1159/000115716. [PMID: 6548970]
  • W A Banks, A J Kastin. CSF-plasma relationships for DSIP and some other neuropeptides. Pharmacology, biochemistry, and behavior. 1983 Dec; 19(6):1037-40. doi: 10.1016/0091-3057(83)90412-4. [PMID: 6689211]
  • W A Banks, A J Kastin, D H Coy. Delta sleep-inducing peptide (DSIP)-like material is absorbed by the gastrointestinal tract of the neonatal rat. Life sciences. 1983 Oct; 33(16):1587-97. doi: 10.1016/0024-3205(83)90700-2. [PMID: 6688848]
  • R Ekman, I Larsson, M Malmquist, J I Thorell. Radioimmunoassay of delta sleep-inducing peptide using an iodinated p-hydroxyphenylpropionic acid derivative as tracer. Regulatory peptides. 1983 Aug; 6(4):371-8. doi: 10.1016/0167-0115(83)90266-5. [PMID: 6688882]
  • A J Kastin, W A Banks, P F Castellanos, C Nissen, D H Coy. Differential penetration of DSIP peptides into rat brain. Pharmacology, biochemistry, and behavior. 1982 Dec; 17(6):1187-91. doi: 10.1016/0091-3057(82)90118-6. [PMID: 6897680]
  • W A Banks, A J Kastin, D H Coy. Delta sleep-inducing peptide crosses the blood-brain-barrier in dogs: some correlations with protein binding. Pharmacology, biochemistry, and behavior. 1982 Nov; 17(5):1009-14. doi: 10.1016/0091-3057(82)90486-5. [PMID: 6897451]
  • M Graf, J B Baumann, J Girard, H J Tobler, G A Schoenenberger. DSIP-induced changes of the daily concentrations of brain neurotransmitters and plasma proteins in rats. Pharmacology, biochemistry, and behavior. 1982 Sep; 17(3):511-7. doi: 10.1016/0091-3057(82)90312-4. [PMID: 6128743]
  • A J Kastin, P F Castellanos, W A Banks, D H Coy. Radioimmunoassay of DSIP-like material in human blood: possible protein binding. Pharmacology, biochemistry, and behavior. 1981 Dec; 15(6):969-74. doi: 10.1016/0091-3057(81)90064-2. [PMID: 6895671]
  • A J Kastin, C Nissen, A V Schally, D H Coy. Additional evidence that small amounts of a peptide can cross the blood-brain barrier. Pharmacology, biochemistry, and behavior. 1979 Dec; 11(6):717-9. doi: 10.1016/0091-3057(79)90269-7. [PMID: 583452]