Plomestane (BioDeep_00000668716)
代谢物信息卡片
化学式: C21H26O2 (310.1932696)
中文名称: 普洛美坦
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC3C(C1CCC2=O)CCC4=CC(=O)CCC34CC#C
InChI: InChI=1S/C21H26O2/c1-3-10-21-12-8-15(22)13-14(21)4-5-16-17-6-7-19(23)20(17,2)11-9-18(16)21/h1,13,16-18H,4-12H2,2H3/t16-,17-,18-,20-,21-/m0/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D065088 - Steroid Synthesis Inhibitors
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006727 - Hormone Antagonists > D004965 - Estrogen Antagonists
C274 - Antineoplastic Agent > C2189 - Signal Transduction Inhibitor > C129824 - Antineoplastic Protein Inhibitor
D004791 - Enzyme Inhibitors > D065088 - Steroid Synthesis Inhibitors > D047072 - Aromatase Inhibitors
C274 - Antineoplastic Agent > C129818 - Antineoplastic Hormonal/Endocrine Agent > C481 - Antiestrogen
C274 - Antineoplastic Agent > C163758 - Targeted Therapy Agent > C1740 - Aromatase Inhibitor
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
C471 - Enzyme Inhibitor > C129825 - Antineoplastic Enzyme Inhibitor
C147908 - Hormone Therapy Agent > C547 - Hormone Antagonist
D000970 - Antineoplastic Agents
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:
- PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。
文献列表
- E P Gomez-Sanchez, C E Gomez-Sanchez. The effect of gonadectomy and aromatase inhibition on the excretion of 19-nordeoxycorticosterone in rats.
The Journal of steroid biochemistry and molecular biology.
1991 Aug; 39(2):185-8. doi:
10.1016/0960-0760(91)90061-9
. [PMID: 1888677] - G T Griffing, J C Melby, M Holbrook, O N Johnston. Antihypertensive effects of an aromatase inhibitor in inbred salt-sensitive rats.
Hypertension (Dallas, Tex. : 1979).
1991 Jun; 17(6 Pt 1):771-5. doi:
10.1161/01.hyp.17.6.771
. [PMID: 2045138] - T Zaccheo, D Giudici, G Ornati, A Panzeri, E di Salle. Comparison of the effects of the irreversible aromatase inhibitor exemestane with atamestane and MDL 18962 in rats with DMBA-induced mammary tumours.
European journal of cancer (Oxford, England : 1990).
1991; 27(9):1145-50. doi:
10.1016/0277-5379(91)90313-3
. [PMID: 1835626] - M E Brandt, D Puett, D F Covey, S J Zimniski. Characterization of pregnant mare's serum gonadotropin-stimulated rat ovarian aromatase and its inhibition by 10-propargylestr-4-ene-3,17-dione.
Journal of steroid biochemistry.
1988 Sep; 31(3):317-24. doi:
10.1016/0022-4731(88)90356-1
. [PMID: 3419162] - C Longcope, A Femino, J O Johnston. Inhibition of peripheral aromatization in baboons by an enzyme-activated aromatase inhibitor (MDL 18,962).
Endocrinology.
1988 May; 122(5):2007-11. doi:
10.1210/endo-122-5-2007
. [PMID: 3359974] - J C Melby, M Holbrook, G T Griffing, J O Johnston. Antihypertensive effects of an aromatase inhibitor in the spontaneously hypertensive rat.
Hypertension (Dallas, Tex. : 1979).
1987 Nov; 10(5):484-7. doi:
10.1161/01.hyp.10.5.484
. [PMID: 3666863] - C Longcope. Peripheral aromatization: studies on controlling factors.
Steroids.
1987 Jul; 50(1-3):253-67. doi:
10.1016/0039-128x(83)90076-4
. [PMID: 2847371]