Proligestone (BioDeep_00000668583)
代谢物信息卡片
化学式: C24H34O4 (386.2457)
中文名称: 普罗孕酮
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1OC23CCC(C2(CCC4C3CCC5=CC(=O)CCC45C)C)(O1)C(=O)C
InChI: InChI=1S/C24H34O4/c1-5-20-27-23(15(2)25)12-13-24(28-20)19-7-6-16-14-17(26)8-10-21(16,3)18(19)9-11-22(23,24)4/h14,18-20H,5-13H2,1-4H3/t18-,19+,20?,21-,22+,23-,24+/m0/s1
描述信息
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones
同义名列表
2 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
|---|
文献列表
- D Meisl, M Hubler, S Arnold. [Treatment of fibroepithelial hyperplasia (FEH) of the mammary gland in the cat with the progesterone antagonist Aglépristone (Alizine)].
Schweizer Archiv fur Tierheilkunde.
2003 Mar; 145(3):130-6. doi:
10.1024/0036-7281.145.3.130. [PMID: 12677773] - P J Selman, J A Mol, G R Rutteman, E van Garderen, T S van den Ingh, A Rijnberk. Effects of progestin administration on the hypothalamic-pituitary-adrenal axis and glucose homeostasis in dogs.
Journal of reproduction and fertility. Supplement.
1997; 51(?):345-54. doi:
NULL. [PMID: 9404305] - P J Selman, J Wolfswinkel, J A Mol. Binding specificity of medroxyprogesterone acetate and proligestone for the progesterone and glucocorticoid receptor in the dog.
Steroids.
1996 Mar; 61(3):133-7. doi:
10.1016/0039-128x(95)00216-d. [PMID: 8852830] - P J Selman, E van Garderen, J A Mol, T S van den Ingh. Comparison of the histological changes in the dog after treatment with the progestins medroxyprogesterone acetate and proligestone.
The veterinary quarterly.
1995 Dec; 17(4):128-33. doi:
10.1080/01652176.1995.9694551. [PMID: 8751273] - P J Selman, J A Mol, G R Rutteman, A Rijnberk. Progestin treatment in the dog. I. Effects on growth hormone, insulin-like growth factor I and glucose homeostasis.
European journal of endocrinology.
1994 Oct; 131(4):413-21. doi:
10.1530/eje.0.1310413. [PMID: 7921231] - P J Selman, J A Mol, G R Rutteman, A Rijnberk. Progestin treatment in the dog. II. Effects on the hypothalamic-pituitary-adrenocortical axis.
European journal of endocrinology.
1994 Oct; 131(4):422-30. doi:
10.1530/eje.0.1310422. [PMID: 7921232] - D B Church, A D Watson, D R Emslie, D J Middleton, K Tan, D Wong. Effects of proligestone and megestrol on plasma adrenocorticotrophic hormone, insulin and insulin-like growth factor-1 concentrations in cats.
Research in veterinary science.
1994 Mar; 56(2):175-8. doi:
10.1016/0034-5288(94)90101-5. [PMID: 8191007] - A D Watson, D B Church, D R Emslie, D J Middleton. Comparative effects of proligestone and megestrol acetate on basal plasma glucose concentrations and cortisol responses to exogenous adrenocorticotrophic hormone in cats.
Research in veterinary science.
1989 Nov; 47(3):374-6. doi:
. [PMID: 2556766] - R F Witkamp, S M Nijmeijer, C T Van Duin, M M Bevers, T Wensing, H Van Gogh, A S Van Miert. Has bovine somatotropin (BST) an effect upon drug disposition? Comparative studies in goats and cattle with sulphadimidine and antipyrine after parenteral administration of BST, zeranol and proligestone.
Journal of veterinary pharmacology and therapeutics.
1989 Jun; 12(2):163-78. doi:
10.1111/j.1365-2885.1989.tb00658.x. [PMID: 2746723]
