Pirinixil (BioDeep_00000668538)
代谢物信息卡片
化学式: C16H19ClN4O2S (366.0917184)
中文名称: 匹立昔尔
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=C(C(=CC=C1)NC2=CC(=NC(=N2)SCC(=O)NCCO)Cl)C
InChI: InChI=1S/C16H19ClN4O2S/c1-10-4-3-5-12(11(10)2)19-14-8-13(17)20-16(21-14)24-9-15(23)18-6-7-22/h3-5,8,22H,6-7,9H2,1-2H3,(H,18,23)(H,19,20,21)
描述信息
C78276 - Agent Affecting Digestive System or Metabolism > C29703 - Antilipidemic Agent
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- P K Eagon, A G Teepe, M S Elm, S D Tadic, M J Epley, B E Beiler, H Shinozuka, K N Rao. Hepatic hyperplasia and cancer in rats: alterations in copper metabolism.
Carcinogenesis.
1999 Jun; 20(6):1091-6. doi:
10.1093/carcin/20.6.1091. [PMID: 10357793] - T Ohmura, S L Katyal, J Locker, G M Ledda-Columbano, A Columbano, H Shinozuka. Induction of cellular DNA synthesis in the pancreas and kidneys of rats by peroxisome proliferators, 9-cis retinoic acid, and 3,3',5-triiodo-L-thyronine.
Cancer research.
1997 Mar; 57(5):795-8. doi:
NULL. [PMID: 9041172] - M Masuhara, S L Katyal, T Nakamura, H Shinozuka. Differential expression of hepatocyte growth factor, transforming growth factor-alpha and transforming growth factor-beta 1 messenger RNAs in two experimental models of liver cell proliferation.
Hepatology (Baltimore, Md.).
1992 Nov; 16(5):1241-9. doi:
10.1002/hep.1840160522. [PMID: 1427663] - M I Perera, S L Katyal, H Shinozuka. Suppression of choline-deficient diet-induced hepatocyte membrane lipid peroxidation in rats by the peroxisome proliferators 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthio(N-beta-hydroxyethyl)- acetamide and di(2-ethylhexyl)phthalate.
Cancer research.
1986 Jul; 46(7):3304-8. doi:
". [PMID: 3708564] - P Cozzi, U Branzoli, P P Lovisolo, G Orsini, G Carganico, A Pillan, A Chiari. N-imidazolylchroman-4-ones, N-imidazolyl-1-tetralones, and their alcohols as hypolipemic agents raising high-density lipoproteins.
Journal of medicinal chemistry.
1986 Mar; 29(3):404-10. doi:
10.1021/jm00153a016. [PMID: 3950919] - M R Lovati, G De Marchi. Plasma lipoprotein composition in cholesterol fed rabbits treated with pirinixil (BR 931), a new lipid lowering agent.
Pharmacological research communications.
1981 Feb; 13(2):133-9. doi:
10.1016/s0031-6989(81)80014-8. [PMID: 7220573] - G D'Atri, P Gomarasca, E Galimberti, C R Sirtori, D Kritchevsky. Clofibrate, pirinixil (BR 931) and WY-14,643 do not affect body cholesterol in Sprague-Dawley rats.
Atherosclerosis.
1980 Nov; 37(3):475-83. doi:
10.1016/0021-9150(80)90154-9. [PMID: 7458993] - D Kritchevsky, D M Klurfeld, S A Tepper, M A Mueller, L Puglisi, C R Sirtori. Increased plasma cholesterol and decreased body lipid levels in Wistar rats following pirinixil (BR 931) treatment.
Pharmacological research communications.
1979 Jun; 11(6):475-82. doi:
10.1016/s0031-6989(79)80019-3. [PMID: 504321] - C R Sirtori, P Gomarasca, G D'Atri, S Cerutti, G Tronconi, C Scolastico. Pharmacological profile of BR-931, a new hypolipidemic agent that increases high-density lipoproteins.
Atherosclerosis.
1978 May; 30(1):45-56. doi:
10.1016/0021-9150(78)90151-x. [PMID: 209796]