apalcillin sodium (BioDeep_00000667553)
代谢物信息卡片
apalcillin sodium
化学式: C25H22N5NaO6S (543.1188432)
中文名称: 阿帕西林钠
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1(C(N2C(S1)C(C2=O)NC(=O)C(C3=CC=CC=C3)NC(=O)C4=CNC5=C(C4=O)N=CC=C5)C(=O)[O-])C.[Na+]
InChI: /q
描述信息
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic
同义名列表
1 个代谢物同义名
数据库引用编号
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代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
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Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
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0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- J P Fillastre, B Moulin, S Josse, J H Frelon. [Apalcillin and renal function].
Pathologie-biologie.
1988 Jun; 36(5 Pt 2):694-8. doi:
NULL. [PMID: 3054749] - J P Fillastre, B Moulin, M Godin, J H Frelon. Is apalcillin nephrotoxic?.
Antimicrobial agents and chemotherapy.
1988 Jun; 32(6):942-4. doi:
10.1128/aac.32.6.942. [PMID: 3415216] - A W Mondorf, S Renelt, A Klingen. [Kidney tolerance of apalcillin. Studies with apalcillin as a monosubstance and in combination with gentamycin].
Fortschritte der Medizin.
1987 Oct; 105(30):596-8. doi:
NULL. [PMID: 3679057] - J M Brogard, J P Arnaud, J F Blickle, M Dorner, F Lautier. Biliary elimination of apalcillin: an experimental and clinical study.
International journal of clinical pharmacology, therapy, and toxicology.
1986 Apr; 24(4):180-7. doi:
NULL. [PMID: 3710630] - F M Demotes-Mainard, G A Vinçon, C H Jarry, G L Bourgeois, H C Albin. High-performance liquid chromatographic determination of apalcillin in plasma and urine.
Journal of chromatography.
1985 Jul; 342(1):234-40. doi:
10.1016/s0378-4347(00)84510-7. [PMID: 4044754] - L O Gentry, B A Wood, E A Natelson. Effects of apalcillin on platelet function in normal volunteers.
Antimicrobial agents and chemotherapy.
1985 May; 27(5):683-4. doi:
10.1128/aac.27.5.683. [PMID: 4015065] - J P Akbaraly, J Sarlangue, M Sautarel, G Heinzel, J Peyraud, C Martin. [Pharmacokinetics of apalcillin in pediatrics].
Pathologie-biologie.
1985 May; 33(5):309-12. doi:
NULL. [PMID: 3897959] - J M Brogard, M Adloff, M Pinget, M Dorner, F Lautier. [Biliary excretion of apalcillin. Experimental study and evaluation in man].
Pathologie-biologie.
1985 Feb; 33(2):121-8. doi:
NULL. [PMID: 3889782] - B M Harnoss, C M Harnoss, K Borner, H Lode, P Koeppe. Biliary elimination of apalcillin in cholecystectomized patients.
Chemotherapy.
1985; 31(4):266-71. doi:
10.1159/000238346. [PMID: 4028872] - K Sato, S Shelton, J D Nelson. Pharmacokinetics and bacteriological efficacies of apalcillin and cefpiramide in experimental pneumococcal meningitis.
Antimicrobial agents and chemotherapy.
1984 Oct; 26(4):578-9. doi:
10.1128/aac.26.4.578. [PMID: 6517548] - J M Brogard, J P Arnaud, J F Blickle, J Lavillaureix. Biliary elimination of apalcillin in humans.
Antimicrobial agents and chemotherapy.
1984 Sep; 26(3):428-30. doi:
10.1128/aac.26.3.428. [PMID: 6508274] - E Bergogne-Berezin, J Pierre, J Chastre, C Gibert, G Heinzel, J P Akbaraly. Pharmacokinetics of apalcillin in intensive-care patients: study of penetration into the respiratory tract.
The Journal of antimicrobial chemotherapy.
1984 Jul; 14(1):67-73. doi:
10.1093/jac/14.1.67. [PMID: 6480542] - J P Akbaraly, A Brachet-Liermain, C Quentin, G Heinzel, M Guyot, C Coux, J Auzerie, C Bebear. [Pharmacokinetics of apalcillin. Study of linearity].
Pathologie-biologie.
1984 May; 32(5):307-11. doi:
NULL. [PMID: 6739139] - H Wexler, W T Carter, B Harris, S M Finegold. Comparative in vitro activities of cefpiramide and apalcillin against anaerobic bacteria.
Antimicrobial agents and chemotherapy.
1984 Feb; 25(2):162-4. doi:
10.1128/aac.25.2.162. [PMID: 6712200] - H Lode, A Elvers, P Koeppe, K Borner. Comparative pharmacokinetics of apalcillin and piperacillin.
Antimicrobial agents and chemotherapy.
1984 Jan; 25(1):105-8. doi:
10.1128/aac.25.1.105. [PMID: 6703672] - A Brachet-Liermain, J P Akbaraly, C Quentin, M Guyot, C Coux, J Auzerie, C Bebear. [Pharmacokinetic study of apalcillin after infusion].
Pathologie-biologie.
1983 May; 31(5):319-22. doi:
NULL. [PMID: 6353324] - K Borner, H Lode, A Elvers. Determination of apalcillin and its metabolites in human body fluids by high-pressure liquid chromatography.
Antimicrobial agents and chemotherapy.
1982 Dec; 22(6):949-53. doi:
10.1128/aac.22.6.949. [PMID: 6818901] - U Busch, G Heinzel, H Seyfarth, H Mielenz. [Investigations on the pharmacokinetics of apalcillin in man].
Arzneimittel-Forschung.
1982; 32(9):1131-5. doi:
NULL. [PMID: 6890838] - Y Watanabe, T Hayashi, R Kitayama, T Yasuda, I Saikawa, K Shimizu. Studies on protein binding of antibiotics. II. Effect of apalcillin on protein binding and pharmacokinetics of cefoperazone and cefazolin.
The Journal of antibiotics.
1981 Jun; 34(6):753-7. doi:
10.7164/antibiotics.34.753. [PMID: 6456252] - K Ohhara, H Kubota, H Hashiba, T Kohchi, T Urushibara, N Kikuchi, T Yotsumoto, K Itoh, K Ichimura, T Uchida, A Kobayashi, H Kanno, N Kikuchi. [Clinical studies on PC-904 in biliary tract diseases (author's transl)].
The Japanese journal of antibiotics.
1979 May; 32(5):631-7. doi:
NULL. [PMID: 459091] - T Kawabata, T Goto, Y Maeyama, Y Ohi. [Fundamental studies and clinical evaluation of PC-904 in urinary tract infection (author's transl)].
The Japanese journal of antibiotics.
1979 Mar; 32(3):306-11. doi:
NULL. [PMID: 108428] - M Okumoto, G Smolin, S Ohno, J Dy-Liacco, G Mintsioulis. In vitro and in vivo effect of PC 904, a new broad-spectrum penicillin, on ocular strains of Pseudomonas aeruginosa.
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie.
1978 Jul; 13(3):200-5. doi:
NULL. [PMID: 100194]