2,4-Dibromoacetophenone (BioDeep_00000667488)

   


代谢物信息卡片


2,4′-dibromoacetophenone

化学式: C8H6Br2O (275.8785)
中文名称: 2,4'-二溴苯乙酮
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC(=CC=C1C(=O)CBr)Br
InChI: InChI=1S/C8H6Br2O/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2

描述信息

D005765 - Gastrointestinal Agents > D000930 - Antidiarrheals
D004791 - Enzyme Inhibitors

同义名列表

2 个代谢物同义名

2,4′-dibromoacetophenone; 2,4-Dibromoacetophenone



数据库引用编号

4 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • T M Baygildiev, I A Rodin, A N Stavrianidi, A V Braun, A T Lebedev, I V Rybalchenko, O A Shpigun. Hydrophilic interaction liquid chromatography-tandem mass spectrometry methylphosponic and alkyl methylphosphonic acids determination in environmental samples after pre-column derivatization with p-bromophenacyl bromide. Journal of chromatography. A. 2016 Apr; 1442(?):19-25. doi: 10.1016/j.chroma.2016.03.001. [PMID: 26965649]
  • Rafael M Ximenes, Renata S Alves, Ticiana P Pereira, Renata M Araújo, Edilberto R Silveira, Marcelo M Rabello, Marcelo Z Hernandes, Veronica C G Soares, Daniel Bristot, Camila L Pires, Daniela O Toyama, Henrique H Gaeta, Helena S A Monteiro, Marcos H Toyama. Harpalycin 2 inhibits the enzymatic and platelet aggregation activities of PrTX-III, a D49 phospholipase A2 from Bothrops pirajai venom. BMC complementary and alternative medicine. 2012 Aug; 12(?):139. doi: 10.1186/1472-6882-12-139. [PMID: 22925825]
  • He-ying Liu, Li Ding, Yong Yu, Yan Chu, He Zhu. Comparison of three derivatization reagents for the simultaneous determination of highly hydrophilic pyrimidine antitumor agents in human plasma by LC-MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2012 Apr; 893-894(?):49-56. doi: 10.1016/j.jchromb.2012.02.033. [PMID: 22429875]
  • Lucy M Elphick, Nadine Pawolleck, Irina A Guschina, Leila Chaieb, Daniel Eikel, Heinz Nau, John L Harwood, Nick J Plant, Robin S B Williams. Conserved valproic-acid-induced lipid droplet formation in Dictyostelium and human hepatocytes identifies structurally active compounds. Disease models & mechanisms. 2012 Mar; 5(2):231-40. doi: 10.1242/dmm.008391. [PMID: 22003123]
  • Jolanta E Damas, Max H Cake. An albumin-associated PLA2-like activity inactivates surfactant phosphatidylcholine secreted from fetal type II pneumocytes. American journal of physiology. Lung cellular and molecular physiology. 2011 Dec; 301(6):L966-74. doi: 10.1152/ajplung.00103.2011. [PMID: 21908590]
  • Aegean Chan, Theodora Mauro. Acidification in the epidermis and the role of secretory phospholipases. Dermato-endocrinology. 2011 Apr; 3(2):84-90. doi: 10.4161/derm.3.2.15140. [PMID: 21695017]
  • Mandi Wiley, Crystal Teygong, Eric Phelps, Jay Radke, Ira J Blader. Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells. PloS one. 2011 Mar; 6(3):e18335. doi: 10.1371/journal.pone.0018335. [PMID: 21479245]
  • Juliana I Dos Santos, Fábio F Cardoso, Andreimar M Soares, Maeli Dal Pai Silva, Márcia Gallacci, Marcos R M Fontes. Structural and functional studies of a bothropic myotoxin complexed to rosmarinic acid: new insights into Lys49-PLA₂ inhibition. PloS one. 2011; 6(12):e28521. doi: 10.1371/journal.pone.0028521. [PMID: 22205953]
  • Christian Harteneck, Maik Gollasch. Pharmacological modulation of diacylglycerol-sensitive TRPC3/6/7 channels. Current pharmaceutical biotechnology. 2011 Jan; 12(1):35-41. doi: 10.2174/138920111793937943. [PMID: 20932261]
  • Mark Merchant, Kate Juneau, Jared Gemillion, Rodolfo Falconi, Aaron Doucet, Matthew H Shirley. Characterization of serum phospholipase a(2) activity in three diverse species of west african crocodiles. Biochemistry research international. 2011; 2011(?):925012. doi: 10.1155/2011/925012. [PMID: 22110960]
  • Hae Jin Kim, Sung Han Ok, Sung Chul Bahn, Juno Jang, Sung Aeong Oh, Soon Ki Park, David Twell, Stephen Beungtae Ryu, Jeong Sheop Shin. Endoplasmic reticulum- and Golgi-localized phospholipase A2 plays critical roles in Arabidopsis pollen development and germination. The Plant cell. 2011 Jan; 23(1):94-110. doi: 10.1105/tpc.110.074799. [PMID: 21278126]
  • Naoaki Harada, Juan Zhao, Hiroki Kurihara, Naomi Nakagata, Kenji Okajima. Stimulation of Fc gammaRI on primary sensory neurons increases insulin-like growth factor-I production, thereby reducing reperfusion-induced renal injury in mice. Journal of immunology (Baltimore, Md. : 1950). 2010 Jul; 185(2):1303-10. doi: 10.4049/jimmunol.0902051. [PMID: 20548031]
  • Mark Merchant, Raphiel Heard, Caleb Monroe. Characterization of phospholipase A(2) activity in serum of the American alligator (Alligator mississippiensis). Journal of experimental zoology. Part A, Ecological genetics and physiology. 2009 Nov; 311(9):662-6. doi: 10.1002/jez.553. [PMID: 19642205]
  • Heiki Vija, Mari Samel, Ene Siigur, Anu Aaspõllu, Katrin Trummal, Külli Tõnismägi, Juhan Subbi, Jüri Siigur. Purification, characterization, and cDNA cloning of acidic platelet aggregation inhibiting phospholipases A(2) from the snake venom of Vipera lebetina (Levantine viper). Toxicon : official journal of the International Society on Toxinology. 2009 Sep; 54(4):429-39. doi: 10.1016/j.toxicon.2009.05.010. [PMID: 19467252]
  • René D Martins, Renata S Alves, Alice M C Martins, Paulo Sergio F Barbosa, Janaina S A M Evangelista, João José F Evangelista, Rafael M Ximenes, Marcos H Toyama, Daniela O Toyama, Alex Jardelino F Souza, Diego J B Orts, Sérgio Marangoni, Dalgimar B de Menezes, Manassés C Fonteles, Helena S A Monteiro. Purification and characterization of the biological effects of phospholipase A(2) from sea anemone Bunodosoma caissarum. Toxicon : official journal of the International Society on Toxinology. 2009 Sep; 54(4):413-20. doi: 10.1016/j.toxicon.2009.05.005. [PMID: 19463845]
  • Szende Vancea, Silvia Imre, Gabriella Donáth-Nagy, Tokés Béla, Mária Nyulas, Teofil Muntean, Réka Borka-Balás. Determination of free captopril in human plasma by liquid chromatography with mass spectrometry detection. Talanta. 2009 Jul; 79(2):436-41. doi: 10.1016/j.talanta.2009.04.003. [PMID: 19559901]
  • Svetlana I Galkina, Julia M Romanova, Vladimir I Stadnichuk, Julian G Molotkovsky, Galina F Sud'ina, Thomas Klein. Nitric oxide-induced membrane tubulovesicular extensions (cytonemes) of human neutrophils catch and hold Salmonella enterica serovar Typhimurium at a distance from the cell surface. FEMS immunology and medical microbiology. 2009 Jul; 56(2):162-71. doi: 10.1111/j.1574-695x.2009.00560.x. [PMID: 19453754]
  • Jiyoung Seo, Hyoung Yool Lee, Hyunju Choi, Yunjung Choi, Yuree Lee, Yong-Woo Kim, Stephen Beungtae Ryu, Youngsook Lee. Phospholipase A2beta mediates light-induced stomatal opening in Arabidopsis. Journal of experimental botany. 2008; 59(13):3587-94. doi: 10.1093/jxb/ern208. [PMID: 18725378]
  • Johanna Mansfeld, Renate Ulbrich-Hofmann. Secretory phospholipase A2-alpha from Arabidopsis thaliana: functional parameters and substrate preference. Chemistry and physics of lipids. 2007 Dec; 150(2):156-66. doi: 10.1016/j.chemphyslip.2007.07.001. [PMID: 17692835]
  • Tae Chul Moon, So Young Son, Hyeun Wook Chang. Purification and characterization of 45 kDa PAF acetylhydrolase from bovine colostrum. Biological & pharmaceutical bulletin. 2007 Sep; 30(9):1668-73. doi: 10.1248/bpb.30.1668. [PMID: 17827718]
  • André L Fuly, Alexandre L Machado, Paulo Castro, Agessandro Abrahão, Paulo Redner, Ulisses G Lopes, Jorge A Guimarães, Vera Lucia G Koatz. Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector. Toxicon : official journal of the International Society on Toxinology. 2007 Sep; 50(3):400-10. doi: 10.1016/j.toxicon.2007.04.008. [PMID: 17537472]
  • Jeanne Claine de Albuquerque Modesto, Patrick J Spencer, Márcio Fritzen, Renata C Valença, Maria Luíza Vilela Oliva, Marcia Bezerra da Silva, Ana Marisa Chudzinski-Tavassi, Miriam Camargo Guarnieri. BE-I-PLA2, a novel acidic phospholipase A2 from Bothrops erythromelas venom: isolation, cloning and characterization as potent anti-platelet and inductor of prostaglandin I2 release by endothelial cells. Biochemical pharmacology. 2006 Jul; 72(3):377-84. doi: 10.1016/j.bcp.2006.04.032. [PMID: 16750518]
  • Taomin Huang, Zhong He, Bei Yang, Luping Shao, Xiaowei Zheng, Gengli Duan. Simultaneous determination of captopril and hydrochlorothiazide in human plasma by reverse-phase HPLC from linear gradient elution. Journal of pharmaceutical and biomedical analysis. 2006 May; 41(2):644-8. doi: 10.1016/j.jpba.2005.12.007. [PMID: 16413728]
  • Helio M Costa-Junior, Flávia C Hamaty, Rafael da Silva Farias, Marcelo Einicker-Lamas, Maria H da Silva, Pedro M Persechini. Apoptosis-inducing factor of a cytotoxic T cell line: involvement of a secretory phospholipase A2. Cell and tissue research. 2006 May; 324(2):255-66. doi: 10.1007/s00441-005-0095-y. [PMID: 16609916]
  • P S F Barbosa, A M C Martins, A Havt, Daniela O Toyama, J S A M Evangelista, D P P Ferreira, P P Joazeiro, Luis O S Beriam, Marcos H Toyama, M C Fonteles, H S A Monteiro. Renal and antibacterial effects induced by myotoxin I and II isolated from Bothrops jararacussu venom. Toxicon : official journal of the International Society on Toxinology. 2005 Sep; 46(4):376-86. doi: 10.1016/j.toxicon.2005.04.024. [PMID: 16115661]
  • Christopher L Sprague, Adnan A Elfarra. Protection of rats against 3-butene-1,2-diol-induced hepatotoxicity and hypoglycemia by N-acetyl-l-cysteine. Toxicology and applied pharmacology. 2005 Sep; 207(3):266-74. doi: 10.1016/j.taap.2005.01.007. [PMID: 16129119]
  • Ihsan Ergün, M Cenk Akbostanci, Başol Canbakan, Bilge Koçer, Arzu Ensari, Gökhan Nergizoglu, Kenan Keven. Minimal change nephrotic syndrome with stiff-person syndrome: is there a link?. American journal of kidney diseases : the official journal of the National Kidney Foundation. 2005 Jul; 46(1):e11-4. doi: 10.1053/j.ajkd.2005.03.009. [PMID: 15983949]
  • Svetlana I Galkina, Julian G Molotkovsky, Volker Ullrich, Galina F Sud'ina. Scanning electron microscopy study of neutrophil membrane tubulovesicular extensions (cytonemes) and their role in anchoring, aggregation and phagocytosis. The effect of nitric oxide. Experimental cell research. 2005 Apr; 304(2):620-9. doi: 10.1016/j.yexcr.2004.12.005. [PMID: 15748905]
  • Arjun Ram, Moumita Das, Sharad V Gangal, Balaram Ghosh. Para-Bromophenacyl bromide alleviates airway hyperresponsiveness and modulates cytokines, IgE and eosinophil levels in ovalbumin-sensitized and -challenged mice. International immunopharmacology. 2004 Dec; 4(13):1697-707. doi: 10.1016/j.intimp.2004.08.001. [PMID: 15454121]
  • Patrícia G Roberto, Simone Kashima, Silvana Marcussi, José O Pereira, Spartaco Astolfi-Filho, Auro Nomizo, José R Giglio, Marcos R M Fontes, Andreimar M Soares, Suzelei C França. Cloning and identification of a complete cDNA coding for a bactericidal and antitumoral acidic phospholipase A2 from Bothrops jararacussu venom. The protein journal. 2004 May; 23(4):273-85. doi: 10.1023/b:jopc.0000027852.92208.60. [PMID: 15214498]
  • Scott C Boegeman, Raymond A Deems, Edward A Dennis. Phospholipid binding and the activation of group IA secreted phospholipase A2. Biochemistry. 2004 Apr; 43(13):3907-16. doi: 10.1021/bi035921b. [PMID: 15049698]
  • Ji-Biao Huang, Yuji Takeda, Yoshihiko Araki, Fujiro Sendo, Howard R Petty. Molecular proximity of complement receptor type 3 (CR3) and the glycosylphosphatidylinositol-linked protein GPI-80 on neutrophils: effects of cell adherence, exogenous saccharides, and lipid raft disrupting agents. Molecular immunology. 2004 Mar; 40(17):1249-56. doi: 10.1016/j.molimm.2003.11.033. [PMID: 15128041]
  • Andreimar M Soares, Wladimir P Sestito, Silvana Marcussi, Rodrigo G Stábeli, Silvia H Andrião-Escarso, Odete A B Cunha, Carlos A Vieira, José R Giglio. Alkylation of myotoxic phospholipases A2 in Bothrops moojeni venom: a promising approach to an enhanced antivenom production. The international journal of biochemistry & cell biology. 2004 Feb; 36(2):258-70. doi: 10.1016/s1357-2725(03)00237-1. [PMID: 14643891]
  • Youngjin Park, Yonggyun Kim. Xenorhabdus nematophilus inhibits p-bromophenacyl bromide (BPB)-sensitive PLA2 of Spodoptera exigua. Archives of insect biochemistry and physiology. 2003 Nov; 54(3):134-42. doi: 10.1002/arch.10108. [PMID: 14571507]
  • André L Fuly, Sabrina Calil-Elias, Ana Maria B Martinez, Paulo A Melo, Jorge A Guimarães. Myotoxicity induced by an acidic Asp-49 phospholipase A(2) isolated from Lachesis muta snake venom. Comparison with lysophosphatidylcholine. The international journal of biochemistry & cell biology. 2003 Oct; 35(10):1470-81. doi: 10.1016/s1357-2725(03)00129-8. [PMID: 12818242]
  • Tae Chul Moon, Mi Suk Kim, Su Jeong Lee, Tae Yoon Lee, Soon Hak Kwon, Suk Hwan Baek, Hyeun Wook Chang. Detection and characterization of 45 kDa platelet activating factor acetylhydrolase in cerebrospinal fluid of children with meningitis. Archives of pharmacal research. 2003 Jul; 26(7):554-8. doi: 10.1007/bf02976880. [PMID: 12934648]
  • Matthew S Geddis, Vincent Rehder. Initial stages of neural regeneration in Helisoma trivolvis are dependent upon PLA2 activity. Journal of neurobiology. 2003 Mar; 54(4):555-65. doi: 10.1002/neu.10183. [PMID: 12555268]
  • Suren A Tatulian. Structural effects of covalent inhibition of phospholipase A2 suggest allosteric coupling between membrane binding and catalytic sites. Biophysical journal. 2003 Mar; 84(3):1773-83. doi: 10.1016/s0006-3495(03)74985-6. [PMID: 12609879]
  • D Sun, J E Steele. Control of phospholipase A(2) activity in cockroach (Periplaneta americana) fat body trophocytes by hypertrehalosemic hormone: the role of calcium. Insect biochemistry and molecular biology. 2002 Sep; 32(9):1133-42. doi: 10.1016/s0965-1748(02)00049-8. [PMID: 12213248]
  • W A Oleszek. Chromatographic determination of plant saponins. Journal of chromatography. A. 2002 Aug; 967(1):147-62. doi: 10.1016/s0021-9673(01)01556-4. [PMID: 12219927]
  • P W Rieck, S Cholidis, C Hartmann. Intracellular signaling pathway of FGF-2-modulated corneal endothelial cell migration during wound healing in vitro. Experimental eye research. 2001 Nov; 73(5):639-50. doi: 10.1006/exer.2001.1067. [PMID: 11747364]
  • P Green, S Glozman, E Yavin. Ethyl docosahexaenoate-associated decrease in fetal brain lipid peroxide production is mediated by activation of prostanoid and nitric oxide pathways. Biochimica et biophysica acta. 2001 Mar; 1531(1-2):156-64. doi: 10.1016/s1388-1981(01)00101-9. [PMID: 11278180]
  • L M Rudrammaji, K D Machiah, T P Kantha, T V Gowda. Role of catalytic function in the antiplatelet activity of phospholipase A2 cobra (Naja naja naja) venom. Molecular and cellular biochemistry. 2001 Mar; 219(1-2):39-44. doi: 10.1023/a:1011002606505. [PMID: 11354251]
  • Iu N Valitova, L Kh Gordon, T I Ogorodnikova, A V Lygin, N F Ruban. [Respiration of wheat roots during inhibition of phospholipase A2 by 4-bromphenacylbromide]. Tsitologiia. 2001; 43(7):670-3. doi: . [PMID: 11552649]
  • N Nishimura, J Zhang, M Abo, A Okubo, S Yamazaki. Application of capillary electrophoresis to the simultaneous determination of betaines in plants. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 2001 Jan; 17(1):103-6. doi: 10.2116/analsci.17.103. [PMID: 11993643]
  • C Lans, T Harper, K Georges, E Bridgewater. Medicinal and ethnoveterinary remedies of hunters in Trinidad. BMC complementary and alternative medicine. 2001; 1(?):10. doi: 10.1186/1472-6882-1-10. [PMID: 11737880]
  • Y Valitova, L Gordon, T I Ogorodnikova, A V Lygin. The role of phospholipase A2 in the changes in oxygen consumption by wheat roots after their mechanical damage. Doklady. Biochemistry and biophysics. 2001 Jan; 376(?):44-5. doi: 10.1023/a:1018856211302. [PMID: 11712132]
  • R A Ignotz, T Honeyman. TGF-beta signaling in A549 lung carcinoma cells: lipid second messengers. Journal of cellular biochemistry. 2000 Jun; 78(4):588-94. doi: 10.1002/1097-4644(20000915)78:4<588::aid-jcb8>3.0.co;2-6. [PMID: 10861856]
  • W E Longo, E M Grossmann, B Erickson, N Panesar, J E Mazuski, D L Kaminski. The effect of phospholipase A2 inhibitors on proliferation and apoptosis of murine intestinal cells. The Journal of surgical research. 1999 Jun; 84(1):51-6. doi: 10.1006/jsre.1999.5603. [PMID: 10334889]
  • M M Whalen, R N Doshi, B W Bader, A D Bankhurst. Lysophosphatidylcholine and arachidonic acid are required in the cytotoxic response of human natural killer cells to tumor target cells. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 1999; 9(6):297-309. doi: 10.1159/000016324. [PMID: 10749996]
  • P A Melo, C L Ownby. Ability of wedelolactone, heparin, and para-bromophenacyl bromide to antagonize the myotoxic effects of two crotaline venoms and their PLA2 myotoxins. Toxicon : official journal of the International Society on Toxinology. 1999 Jan; 37(1):199-215. doi: 10.1016/s0041-0101(98)00183-4. [PMID: 9920492]
  • M Madesh, K A Balasubramanian. Activation of liver mitochondrial phospholipase A2 by superoxide. Archives of biochemistry and biophysics. 1997 Oct; 346(2):187-92. doi: 10.1006/abbi.1997.0288. [PMID: 9343365]
  • D G Tang, K L Guan, L Li, K V Honn, Y Q Chen, R L Rice, J D Taylor, A T Porter. Suppression of W256 carcinosarcoma cell apoptosis by arachidonic acid and other polyunsaturated fatty acids. International journal of cancer. 1997 Sep; 72(6):1078-87. doi: 10.1002/(sici)1097-0215(19970917)72:6<1078::aid-ijc24>3.0.co;2-#. [PMID: 9378543]
  • Y Kamata, M Mita, A Fujiwara, T Tojo, J Takano, A Ide, I Yasumasu. Probable participation of phospholipase A2 reaction in the process of fertilization-induced activation of sea urchin eggs. Development, growth & differentiation. 1997 Aug; 39(4):419-28. doi: 10.1046/j.1440-169x.1997.t01-3-00002.x. [PMID: 9352195]
  • P Kovács, G Csaba. PLA2 activity in Tetrahymena pyriformis. Effects of inhibitors and stimulators. Journal of lipid mediators and cell signalling. 1997 Mar; 15(3):233-47. doi: 10.1016/s0929-7855(96)00559-7. [PMID: 9041474]
  • S Soubeyrand, A Khadir, Y Brindle, P Manjunath. Purification of a novel phospholipase A2 from bovine seminal plasma. The Journal of biological chemistry. 1997 Jan; 272(1):222-7. doi: 10.1074/jbc.272.1.222. [PMID: 8995251]
  • C L Ownby, J R Powell, M S Jiang, J E Fletcher. Melittin and phospholipase A2 from bee (Apis mellifera) venom cause necrosis of murine skeletal muscle in vivo. Toxicon : official journal of the International Society on Toxinology. 1997 Jan; 35(1):67-80. doi: 10.1016/s0041-0101(96)00078-5. [PMID: 9028010]
  • J Takasaki, Y Kawauchi, T Yasunaga, Y Masuho. Human type II phospholipase A2-induced Mac-1 expression on human neutrophils. Journal of leukocyte biology. 1996 Aug; 60(2):174-80. doi: 10.1002/jlb.60.2.174. [PMID: 8773578]
  • A B Fisher, C Dodia. Role of phospholipase A2 enzymes in degradation of dipalmitoylphosphatidylcholine by granular pneumocytes. Journal of lipid research. 1996 May; 37(5):1057-64. doi: . [PMID: 8725157]
  • G Lombardi, P Leonardi, F Moroni. Metabotropic glutamate receptors, transmitter output and fatty acids: studies in rat brain slices. British journal of pharmacology. 1996 Jan; 117(1):189-95. doi: 10.1111/j.1476-5381.1996.tb15173.x. [PMID: 8825362]
  • M Mao-Qiang, M Jain, K R Feingold, P M Elias. Secretory phospholipase A2 activity is required for permeability barrier homeostasis. The Journal of investigative dermatology. 1996 Jan; 106(1):57-63. doi: 10.1111/1523-1747.ep12327246. [PMID: 8592082]
  • K L Auer, B S Jacobson. Beta 1 integrins signal lipid second messengers required during cell adhesion. Molecular biology of the cell. 1995 Oct; 6(10):1305-13. doi: 10.1091/mbc.6.10.1305. [PMID: 8573788]
  • E V Davies, M B Hallett. A novel pathway for Ca2+ signalling in neutrophils by immune complexes. Immunology. 1995 Aug; 85(4):538-43. doi: NULL. [PMID: 7558146]
  • O Jeanneton, M Delvaux, A Botella, J Frexinos, L Bueno. Homologous desensitization of PAF receptors via a PGE2-dependent pathway on intestinal smooth muscle. Journal of lipid mediators and cell signalling. 1994 Sep; 10(3):331-44. doi: ". [PMID: 7812681]
  • C Rosales, S L Jones, D McCourt, E J Brown. Bromophenacyl bromide binding to the actin-bundling protein l-plastin inhibits inositol trisphosphate-independent increase in Ca2+ in human neutrophils. Proceedings of the National Academy of Sciences of the United States of America. 1994 Apr; 91(9):3534-8. doi: 10.1073/pnas.91.9.3534. [PMID: 8170942]
  • T F Huang, H S Chiang. Effect on human platelet aggregation of phospholipase A2 purified from Heloderma horridum (beaded lizard) venom. Biochimica et biophysica acta. 1994 Feb; 1211(1):61-8. doi: 10.1016/0005-2760(94)90139-2. [PMID: 8123683]
  • L N Chen, C S Liu, C C Chang. Isolation and characterization of a toxic phospholipase A2 from the venom of the Taiwan habu (Trimeresurus mucrosquamatus). Biotechnology and applied biochemistry. 1994 02; 19(1):61-73. doi: NULL. [PMID: 8136082]
  • R Fabia, A Ar'Rajab, R Willén, R Andersson, S Bengmark. Effect of putative phospholipase A2 inhibitors on acetic acid-induced acute colitis in the rat. The British journal of surgery. 1993 Sep; 80(9):1199-204. doi: 10.1002/bjs.1800800947. [PMID: 8402133]
  • C Díaz, J M Gutiérrez, B Lomonte, J Núñez. p-Bromophenacyl bromide modification of Bothrops asper myotoxin II, a lysine-49 phospholipase A2, affects its pharmacological activities. Toxicon : official journal of the International Society on Toxinology. 1993 Sep; 31(9):1202-6. doi: 10.1016/0041-0101(93)90136-7. [PMID: 8266351]
  • X Wu, K Yao, J C Carlson. Plasma membrane changes in the rat corpus luteum induced by oxygen radical generation. Endocrinology. 1993 Aug; 133(2):491-5. doi: 10.1210/endo.133.2.8344194. [PMID: 8344194]
  • B J Poorthuis, T Jille-Vlcková, W Onkenhout. Determination of acylcarnitines in urine of patients with inborn errors of metabolism using high-performance liquid chromatography after derivatization with 4'-bromophenacylbromide. Clinica chimica acta; international journal of clinical chemistry. 1993 Jul; 216(1-2):53-61. doi: 10.1016/0009-8981(93)90138-t. [PMID: 8222273]
  • C L Ownby, J E Fletcher, T R Colberg. Cardiotoxin 1 from cobra (Naja naja atra) venom causes necrosis of skeletal muscle in vivo. Toxicon : official journal of the International Society on Toxinology. 1993 Jun; 31(6):697-709. doi: 10.1016/0041-0101(93)90376-t. [PMID: 8342169]
  • M Kuno, J Kawawaki, T Shibata, H Gotani. Inhibitors of the arachidonic acid cascade dissociate 48/80-induced Ca2+ influx and Ca2+ release in mast cells. The American journal of physiology. 1993 Apr; 264(4 Pt 1):C912-7. doi: 10.1152/ajpcell.1993.264.4.c912. [PMID: 7682776]
  • M Tadayyon, I C Green. Pharmacological interference with phospholipase A2 activity reveals mechanistic differences between glucose and glyceraldehyde induced insulin release: implication for coupling of glucose metabolism to phospholipase A2 activity. Diabete & metabolisme. 1993 Jan; 19(1):36-43. doi: NULL. [PMID: 8504883]
  • M Chautan, Y Latron, F Anfosso, M C Alessi, H Lafont, I Juhan-Vague, G Nalbone. Phosphatidylinositol turnover during stimulation of plasminogen activator inhibitor-1 secretion induced by oxidized low density lipoproteins in human endothelial cells. Journal of lipid research. 1993 Jan; 34(1):101-10. doi: 10.1016/s0022-2275(20)41324-0. [PMID: 8445334]
  • C J Secombes, A R Cross, G J Sharp, R Garcia. NADPH oxidase-like activity in rainbow trout Oncorhynchus mykiss (Walbaum) macrophages. Developmental and comparative immunology. 1992 Sep; 16(5):405-13. doi: 10.1016/0145-305x(92)90042-b. [PMID: 1426492]
  • P Conlon, M Gervais, S Chaudhari, J Conlon. Effects of Pasteurella haemolytica leukotoxic culture supernatant on bovine neutrophil aggregation. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire. 1992 Jul; 56(3):199-203. doi: . [PMID: 1423054]
  • P A Franken, L Van den Berg, J Huang, P Gunyuzlu, R B Lugtigheid, H M Verheij, G H De Haas. Purification and characterization of a mutant human platelet phospholipase A2 expressed in Escherichia coli. Cleavage of a fusion protein with cyanogen bromide. European journal of biochemistry. 1992 Jan; 203(1-2):89-98. doi: 10.1111/j.1432-1033.1992.tb19832.x. [PMID: 1730245]
  • L R Marinari, J W Berkenkopf, B M Weichman. Characterization of phospholipase A2 activity in rat RPAR-induced pleurisy. Agents and actions. 1991 Sep; 34(1-2):97-9. doi: 10.1007/bf01993248. [PMID: 1838901]
  • W A Cass, G Larson, F A Fitzpatrick, N R Zahniser. Inhibitors of arachidonic acid metabolism: effects on rat striatal dopamine release and uptake. The Journal of pharmacology and experimental therapeutics. 1991 Jun; 257(3):990-6. doi: NULL. [PMID: 1828506]
  • K Satoh, T Imaizumi, Y Kawamura, H Yoshida, M Hiramoto, S Takamatsu, M Takamatsu. Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2. The Journal of clinical investigation. 1991 Feb; 87(2):476-81. doi: 10.1172/jci115020. [PMID: 1846878]
  • E Hildebrandt, J P Albanesi. Identification of a membrane-bound, glycol-stimulated phospholipase A2 located in the secretory granules of the adrenal medulla. Biochemistry. 1991 Jan; 30(2):464-72. doi: 10.1021/bi00216a023. [PMID: 1899026]
  • A Jansson, G Ronquist, G Frithz. Phospholipase A activity in seminal plasma of men attending an infertility clinic. Urologia internationalis. 1991; 46(2):184-8. doi: 10.1159/000282129. [PMID: 2053228]
  • C S Ramesha, L A Taylor. Measurement of arachidonic acid release from human polymorphonuclear neutrophils and platelets: comparison between gas chromatographic and radiometric assays. Analytical biochemistry. 1991 Jan; 192(1):173-80. doi: 10.1016/0003-2697(91)90203-6. [PMID: 2048718]
  • H Mita, T Ishii, K Akiyama, T Tamura, K Tadokoro, H Saito, H Yasueda, T Shida. Enzymatic dispersion of mast cells from human sinus mucosa: characterization of histamine release and its comparison with chopped fragments of the tissue. Life sciences. 1991; 49(20):1477-84. doi: 10.1016/0024-3205(91)90047-f. [PMID: 1719325]
  • V G Gogvadze, N N Bruetovetskiĭ, A A Zhukova. [Participation of phospholipase A2 in uncoupling in rat liver mitochondria induced by products of lipid peroxidation]. Biokhimiia (Moscow, Russia). 1990 Dec; 55(12):2195-9. doi: ". [PMID: 2129018]
  • R O Carlson, I B Levitan. Role of arachidonic acid in depolarization-induced modulation of ion currents in Aplysia giant neurons. Journal of neurophysiology. 1990 Aug; 64(2):341-50. doi: 10.1152/jn.1990.64.2.341. [PMID: 2170593]
  • R O Carlson, I B Levitan. Regulation of intracellular free arachidonic acid in Aplysia nervous system. The Journal of membrane biology. 1990 Jul; 116(3):249-60. doi: 10.1007/bf01868464. [PMID: 2388256]
  • V G Gogvadze, N N Brustovetsky, A A Zhukova. The role of phospholipase A2 in lipid peroxidation-induced fall of membrane potential of rat liver mitochondria. FEBS letters. 1990 May; 264(2):168-70. doi: 10.1016/0014-5793(90)80240-j. [PMID: 2113483]
  • Y Nishizawa, K Nishii, S Kishimoto, K Matsumoto, B Sato. Regulatory role of arachidonic acid-derived metabolites for proliferation of transformed murine Leydig cell in serum-free culture condition. Anticancer research. 1990 Mar; 10(2A):317-22. doi: NULL. [PMID: 2111975]
  • J E Fletcher, K Michaux, M S Jiang. Contribution of bee venom phospholipase A2 contamination in melittin fractions to presumed activation of tissue phospholipase A2. Toxicon : official journal of the International Society on Toxinology. 1990; 28(6):647-56. doi: 10.1016/0041-0101(90)90253-4. [PMID: 2402761]
  • J Klein, P Colin, E Scherer, M Levy, G Koren. Simple measurement of captopril in plasma by high-performance liquid chromatography with ultraviolet detection. Therapeutic drug monitoring. 1990 Jan; 12(1):105-10. doi: 10.1097/00007691-199001000-00019. [PMID: 2406997]
  • Y Shirazi, F A McMorris, M L Shin. Arachidonic acid mobilization and phosphoinositide turnover by the terminal complement complex, C5b-9, in rat oligodendrocyte x C6 glioma cell hybrids. Journal of immunology (Baltimore, Md. : 1950). 1989 Jun; 142(12):4385-91. doi: . [PMID: 2542410]
  • S Sandler, K Bendtzen, L A Borg, D L Eizirik, E Strandell, N Welsh. Studies on the mechanisms causing inhibition of insulin secretion in rat pancreatic islets exposed to human interleukin-1 beta indicate a perturbation in the mitochondrial function. Endocrinology. 1989 Mar; 124(3):1492-501. doi: 10.1210/endo-124-3-1492. [PMID: 2521822]
  • S M Borowitz, C Montgomery. The role of phospholipase A2 in microsomal lipid peroxidation induced with t-butyl hydroperoxide. Biochemical and biophysical research communications. 1989 Feb; 158(3):1021-8. doi: 10.1016/0006-291x(89)92824-6. [PMID: 2920033]
  • C C Leslie, D R Voelker, J Y Channon, M M Wall, P T Zelarney. Properties and purification of an arachidonoyl-hydrolyzing phospholipase A2 from a macrophage cell line, RAW 264.7. Biochimica et biophysica acta. 1988 Dec; 963(3):476-92. doi: 10.1016/0005-2760(88)90316-5. [PMID: 3143418]
  • B S Vishwanath, A A Fawzy, R C Franson. Edema-inducing activity of phospholipase A2 purified from human synovial fluid and inhibition by aristolochic acid. Inflammation. 1988 Dec; 12(6):549-61. doi: 10.1007/bf00914317. [PMID: 3220517]
  • J G Altin, T J Biden, A Karjalainen, F L Bygrave. Exposure to depolarizing concentrations of K+ inhibits hormonally-induced calcium influx in rat liver. Biochemical and biophysical research communications. 1988 Jun; 153(3):1282-9. doi: 10.1016/s0006-291x(88)81367-6. [PMID: 3390184]
  • R D Schwartz, P Skolnick, S M Paul. Regulation of gamma-aminobutyric acid/barbiturate receptor-gated chloride ion flux in brain vesicles by phospholipase A2: possible role of oxygen radicals. Journal of neurochemistry. 1988 Feb; 50(2):565-71. doi: 10.1111/j.1471-4159.1988.tb02948.x. [PMID: 2447244]