WHI-P180 (BioDeep_00000665699)
代谢物信息卡片
化学式: C16H15N3O3 (297.111336)
中文名称: WHI-P180,盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=CC=C3)O)OC
InChI: InChI=1S/C16H15N3O3/c1-21-14-7-12-13(8-15(14)22-2)17-9-18-16(12)19-10-4-3-5-11(20)6-10/h3-9,20H,1-2H3,(H,17,18,19)
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Ru Wang, Hu Liu, Yuan-Yuan You, Xin-Yu Wang, Bing-Bing Lv, Li-Qin Cao, Jia-Yu Xue, Yun-Gen Xu, Lei Shi. Discovery of novel VEGFR-2 inhibitors embedding 6,7-dimethoxyquinazoline and diarylamide fragments.
Bioorganic & medicinal chemistry letters.
2021 03; 36(?):127788. doi:
10.1016/j.bmcl.2021.127788. [PMID: 33460739] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Ran An, Yuichiro Hagiya, Ai Tamura, Shanshan Li, Hikaru Saito, Daisuke Tokushima, Toshihisa Ishikawa. Cellular phototoxicity evoked through the inhibition of human ABC transporter ABCG2 by cyclin-dependent kinase inhibitors in vitro.
Pharmaceutical research.
2009 Feb; 26(2):449-58. doi:
10.1007/s11095-008-9738-5. [PMID: 18841444] - Hui Yu, Zhanli Wang, Liangren Zhang, Jufeng Zhang, Qian Huang. Pharmacophore modeling and in silico screening for new KDR kinase inhibitors.
Bioorganic & medicinal chemistry letters.
2007 Apr; 17(8):2126-33. doi:
10.1016/j.bmcl.2007.01.089. [PMID: 17306530] - L F Hennequin, A P Thomas, C Johnstone, E S Stokes, P A Plé, J J Lohmann, D J Ogilvie, M Dukes, S R Wedge, J O Curwen, J Kendrew, C Lambert-van der Brempt. Design and structure-activity relationship of a new class of potent VEGF receptor tyrosine kinase inhibitors.
Journal of medicinal chemistry.
1999 Dec; 42(26):5369-89. doi:
10.1021/jm990345w. [PMID: 10639280] - C L Chen, R Malaviya, C Navara, H Chen, B Bechard, G Mitcheltree, X P Liu, F M Uckun. Pharmacokinetics and biologic activity of the novel mast cell inhibitor, 4-(3-hydroxyphenyl)-amino-6,7-dimethoxyquinazoline in mice.
Pharmaceutical research.
1999 Jan; 16(1):117-22. doi:
10.1023/a:1018835232027. [PMID: 9950289]