Formycin b (BioDeep_00000664473)

   

Chemicals and Drugs Antibiotics


代谢物信息卡片


7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-3-beta-D-ribofuranosyl-

化学式: C10H12N4O5 (268.08076619999997)
中文名称: 间型霉素B
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=NC2=C(NN=C2C(=O)N1)C3C(C(C(O3)CO)O)O
InChI: InChI=1S/C10H12N4O5/c15-1-3-7(16)8(17)9(19-3)5-4-6(14-13-5)10(18)12-2-11-4/h2-3,7-9,15-17H,1H2,(H,13,14)(H,11,12,18)

描述信息

D000970 - Antineoplastic Agents > D000903 - Antibiotics, Antineoplastic > D005573 - Formycins

同义名列表

3 个代谢物同义名

7H-Pyrazolo[4,3-d]pyrimidin-7-one,1,6-dihydro-3-b-D-ribofuranosyl-; Formycin b; 7H-Pyrazolo[4,3-d]pyrimidin-7-one, 1,4-dihydro-3-beta-D-ribofuranosyl-



数据库引用编号

8 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Meaghan Stolk, Elizabeth Cooper, Greg Vilk, David W Litchfield, James R Hammond. Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2. The Biochemical journal. 2005 Mar; 386(Pt 2):281-9. doi: 10.1042/bj20041571. [PMID: 15500446]
  • James R Hammond, Meaghan Stolk, Richard G E Archer, Kristy McConnell. Pharmacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1. European journal of pharmacology. 2004 Apr; 491(1):9-19. doi: 10.1016/j.ejphar.2004.03.026. [PMID: 15102528]
  • Shirin Arastu-Kapur, Ethan Ford, Buddy Ullman, Nicola S Carter. Functional analysis of an inosine-guanosine transporter from Leishmania donovani. The role of conserved residues, aspartate 389 and arginine 393. The Journal of biological chemistry. 2003 Aug; 278(35):33327-33. doi: 10.1074/jbc.m305141200. [PMID: 12807872]
  • J R Hammond, S Lee, P J Ferguson. [3H]gemcitabine uptake by nucleoside transporters in a human head and neck squamous carcinoma cell line. The Journal of pharmacology and experimental therapeutics. 1999 Mar; 288(3):1185-91. doi: NULL. [PMID: 10027857]
  • K W Jones, R J Rylett, J R Hammond. Effect of cellular differentiation on nucleoside transport in human neuroblastoma cells. Brain research. 1994 Oct; 660(1):104-12. doi: 10.1016/0006-8993(94)90844-3. [PMID: 7827987]
  • J M Aran, P G Plagemann. High-affinity, equilibrative nucleoside transporter of pig kidney cell line (PK-15). Biochimica et biophysica acta. 1992 Jul; 1108(1):67-74. doi: 10.1016/0005-2736(92)90115-3. [PMID: 1379470]
  • M M Gutierrez, C M Brett, R J Ott, A C Hui, K M Giacomini. Nucleoside transport in brush border membrane vesicles from human kidney. Biochimica et biophysica acta. 1992 Mar; 1105(1):1-9. doi: 10.1016/0005-2736(92)90156-g. [PMID: 1567888]
  • E S Jakobs, D J Van Os-Corby, A R Paterson. Expression of sodium-linked nucleoside transport activity in monolayer cultures of IEC-6 intestinal epithelial cells. The Journal of biological chemistry. 1990 Dec; 265(36):22210-6. doi: 10.1016/s0021-9258(18)45691-8. [PMID: 2266122]
  • P G Plagemann, J M Aran. Characterization of Na(+)-dependent, active nucleoside transport in rat and mouse peritoneal macrophages, a mouse macrophage cell line and normal rat kidney cells. Biochimica et biophysica acta. 1990 Oct; 1028(3):289-98. doi: 10.1016/0005-2736(90)90178-q. [PMID: 2223800]
  • C J Bacchi, R L Berens, H C Nathan, R S Klein, I A Elegbe, K V Rao, P P McCann, J J Marr. Synergism between 9-deazainosine and DL-alpha-difluoromethylornithine in treatment of experimental African trypanosomiasis. Antimicrobial agents and chemotherapy. 1987 Sep; 31(9):1406-13. doi: 10.1128/aac.31.9.1406. [PMID: 3118799]
  • D M Iovannisci, B Ullman. Single cell cloning of Leishmania parasites in purine-defined medium: isolation of drug-resistant variants. Advances in experimental medicine and biology. 1984; 165 Pt A(?):239-43. doi: 10.1007/978-1-4684-4553-4_46. [PMID: 6720386]