Benzathine (BioDeep_00000661527)
代谢物信息卡片
N,N-Dibenzylethylenediamine
化学式: C16H20N2 (240.16264)
中文名称: N,N-二苄基乙二胺
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C(C=C1)CNCCNCC2=CC=CC=C2
InChI: InChI=1S/C16H20N2/c1-3-7-15(8-4-1)13-17-11-12-18-14-16-9-5-2-6-10-16/h1-10,17-18H,11-14H2
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:51344
- PubChem: 8793
- ChEMBL: CHEMBL193646
- CAS: 1219795-20-6
- CAS: 140-28-3
- CAS: 14165-27-6
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Daryna B Pylypiv, Boris M Sharga, Olexandr A Rishko, Vitalii Leshak, Elena Karbovanets. Relation of Streptococcus Pyogenes tonsillitis isolate to antimicrobial agents and its infection treatment.
Wiadomosci lekarskie (Warsaw, Poland : 1960).
2024; 77(1):171-177. doi:
10.36740/wlek202401122. [PMID: 38431823] - K Hausler, S M Godden, M J Schneider, A R Lightfield, M Bulthaus, D Haines. Hot topic: investigating the risk of violative meat residues in bob veal calves fed colostrum from cows treated at dry-off with cephapirin benzathine.
Journal of dairy science.
2013 Apr; 96(4):2349-2355. doi:
10.3168/jds.2012-5891. [PMID: 23415519] - Michael P Broderick, Christian J Hansen, Dennis J Faix. Factors associated with loss of penicillin G concentrations in serum after intramuscular benzathine penicillin G injection: a meta-analysis.
The Pediatric infectious disease journal.
2012 Jul; 31(7):722-5. doi:
10.1097/inf.0b013e31825051d4. [PMID: 22481428] - Oriol Mitjà, Russell Hays, Anthony Ipai, Moses Penias, Raymond Paru, David Fagaho, Elisa de Lazzari, Quique Bassat. Single-dose azithromycin versus benzathine benzylpenicillin for treatment of yaws in children in Papua New Guinea: an open-label, non-inferiority, randomised trial.
Lancet (London, England).
2012 Jan; 379(9813):342-7. doi:
10.1016/s0140-6736(11)61624-3. [PMID: 22240407] - Khalil G Ghanem, Kimberly A Workowski. Management of adult syphilis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2011 Dec; 53 Suppl 3(?):S110-28. doi:
10.1093/cid/cir701. [PMID: 22080265] - Rui-Rui Peng, Alberta L Wang, Jing Li, Joseph D Tucker, Yue-Ping Yin, Xiang-Sheng Chen. Molecular typing of Treponema pallidum: a systematic review and meta-analysis.
PLoS neglected tropical diseases.
2011 Nov; 5(11):e1273. doi:
10.1371/journal.pntd.0001273. [PMID: 22087340] - M Daoud, Elena Duca, M Onofriescu, Zenaida Petrescu. [Assessment of the congenital syphilis prevention programs].
Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi.
2011 Jul; 115(3):934-7. doi:
NULL. [PMID: 22046811] - T N Revathi, Shilpa Bhat, G S Asha. Benign nodular tertiary syphilis: a rare presenting manifestation of HIV infection.
Dermatology online journal.
2011 Feb; 17(2):5. doi:
NULL. [PMID: 21382288] - Marco Antonio Batista, Tomaz Puga Leivas, Consuelo Junqueira Rodrigues, Géssica Cantadori Funes Arenas, Donizeti Rodrigues Belitardo, Roberto Guarniero. Comparison between the effects of platelet-rich plasma and bone marrow concentrate on defect consolidation in the rabbit tibia.
Clinics (Sao Paulo, Brazil).
2011; 66(10):1787-92. doi:
10.1590/s1807-593220110007000018. [PMID: 22012052] - P Andrade, N Pereira, M M Brites, M Gonçalo, A Figueiredo. Nicolau livedoid dermatitis following intramuscular benzathine penicillin injection.
Dermatology online journal.
2010 Dec; 16(12):11. doi:
NULL. [PMID: 21199637] - P Andrade, A Mariano, A Figueiredo. Solitary frontal ulcer: A syphilitic gumma.
Dermatology online journal.
2010 Sep; 16(9):5. doi:
NULL. [PMID: 20875326] - Wen-Tao Zhao, Jing Liu, Yu-Ying Li. Syphilitic proctitis mimicking rectal cancer: A case report.
World journal of gastrointestinal pathophysiology.
2010 Aug; 1(3):112-4. doi:
10.4291/wjgp.v1.i3.112. [PMID: 21607150] - Martín B Lasso, M Elvira M Balcells M, Ana S Fernández, Pablo G Gaete, Michel V Serri, Jorge G Pérez, Carolina A Chain, Inés A Cerón, Clara O Duque, Anamaría B Ramírez. [Neurosyphilis in the patients with and without HIV infection: description and comparison of two historical cohorts].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia.
2009 Dec; 26(6):540-7. doi:
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Sexually transmitted diseases.
2009 Nov; 36(11):714-20. doi:
10.1097/olq.0b013e3181bc0960. [PMID: 19773681] - K G H Silva, F H Xavier Júnior, I E G Farias, A K A Silva, J A Caldas Neto, L C A Souza, R R Santiago, F Alexandrino Júnior, T Nagashima Júnior, L A L Soares, N S Santos-Magalhães, E S T Egito. Stationary cuvette: a new approach to obtaining analytical curves by UV-VIS spectrophotometry.
Phytochemical analysis : PCA.
2009 Jul; 20(4):265-71. doi:
10.1002/pca.1122. [PMID: 19333915] - D J Deshpande, C S Nayak, S N Mishra, R S Dhurat. Verrucous condyloma lata mimicking condyloma acuminata: An unusual presentation.
Indian journal of sexually transmitted diseases and AIDS.
2009 Jul; 30(2):100-2. doi:
10.4103/0253-7184.62766. [PMID: 21938129] - Patrick William Woodburn, Lawrence Muhangi, Stephen Hillier, Juliet Ndibazza, Proscovia Bazanya Namujju, Moses Kizza, Christine Ameke, Nicolas Emojong Omoding, Mark Booth, Alison Mary Elliott. Risk factors for helminth, malaria, and HIV infection in pregnancy in Entebbe, Uganda.
PLoS neglected tropical diseases.
2009 Jun; 3(6):e473. doi:
10.1371/journal.pntd.0000473. [PMID: 19564904] - Jun Li, Lin-Na Wang, Ya-Gang Zuo, Yong-Xin Liu, Xiu-Rong Liu, Yang Lei, He-Yi Zheng. [Clinical analysis and study of immunological function in syphilis patients with seroresistance].
Zhonghua yi xue za zhi.
2009 Mar; 89(12):813-6. doi:
NULL. [PMID: 19595119] - Shan-Shan Wu, Wen-Bing Yuan, Hai-Yang Wang, Qi Zhang, Min Liu, Kai-Bei Yu. Synthesis, crystal structure and interaction with DNA and HSA of (N,N'-dibenzylethane-1,2-diamine) transition metal complexes.
Journal of inorganic biochemistry.
2008 Nov; 102(11):2026-34. doi:
10.1016/j.jinorgbio.2008.08.005. [PMID: 18838170] - R De Sousa, A Dang, P V Rataboli. Nicolau syndrome following intramuscular benzathine penicillin.
Journal of postgraduate medicine.
2008 Oct; 54(4):332-4. doi:
10.4103/0022-3859.43523. [PMID: 18953160] - Tom Wong, Ameeta E Singh, Prithwish De. Primary syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin.
The American journal of medicine.
2008 Oct; 121(10):903-8. doi:
10.1016/j.amjmed.2008.04.042. [PMID: 18823862] - Enio Latini Bitarães, Benigna Maria de Oliveira, Marcos Borato Viana. Compliance with antibiotic prophylaxis in children with sickle cell anemia: a prospective study.
Jornal de pediatria.
2008 Jul; 84(4):316-22. doi:
10.2223/jped.1819. [PMID: 18688558] - Vladana Woznicová, Monika Heroldová. Detection of treponema pallidum DNA in the serum of an adequately treated patient with latent syphilis.
Acta dermato-venereologica.
2007; 87(4):379-80. doi:
10.2340/00015555-0259. [PMID: 17598051] - Khalil G Ghanem, Emily J Erbelding, Walter W Cheng, Anne M Rompalo. Doxycycline compared with benzathine penicillin for the treatment of early syphilis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
2006 Mar; 42(6):e45-9. doi:
10.1086/500406. [PMID: 16477545] - Gregg R Ward, Abdel A Abdel-Rahman. Orchiectomy or androgen receptor blockade attenuates baroreflex-mediated bradycardia in conscious rats.
BMC pharmacology.
2006 Jan; 6(?):2. doi:
10.1186/1471-2210-6-2. [PMID: 16430770] - Sung Ho Song, Ick Jang, Bum Sik Kim, Eun Tak Kim, Seung-Hyo Woo, Mee Ja Park, Chang Nam Kim. A case of primary syphilis in the rectum.
Journal of Korean medical science.
2005 Oct; 20(5):886-7. doi:
10.3346/jkms.2005.20.5.886. [PMID: 16224168] - S Mullick, M Beksinksa, S Msomi. Treatment for syphilis in antenatal care: compliance with the three dose standard treatment regimen.
Sexually transmitted infections.
2005 Jun; 81(3):220-2. doi:
10.1136/sti.2004.011999. [PMID: 15923289] - Steven D Burdette, Jill S Waibel, Jack M Bernstein, Julian J Trevino. With this eruption, there is not a second to lues.
Skinmed.
2005 May; 4(3):179-82. doi:
10.1111/j.1540-9740.2005.03963.x. [PMID: 15891256] - Gregg R Ward, Abdel A Abdel-Rahman. Effect of testosterone replacement or duration of castration on baroreflex bradycardia in conscious rats.
BMC pharmacology.
2005 Mar; 5(?):9. doi:
10.1186/1471-2210-5-9. [PMID: 15799780] - Alireza Ghassempour, Saied Saeed Hosseiny Davarani, Massomeh Noroozi, Mojtaba Shamsipur. Determination of ternary mixtures of penicillin G, benzathine and procaine by liquid chromatography and factorial design study.
Talanta.
2005 Feb; 65(4):1038-44. doi:
10.1016/j.talanta.2004.08.042. [PMID: 18969907] - P Gaig, M J Paniagua. [Hoigne's syndrome].
Allergologia et immunopathologia.
2005 Jan; 33(1):57-8. doi:
10.1157/13070611. [PMID: 15777526] - Landon Myer, Salim S Abdool Karim, Carl Lombard, David Wilkinson. Treatment of maternal syphilis in rural South Africa: effect of multiple doses of benzathine penicillin on pregnancy loss.
Tropical medicine & international health : TM & IH.
2004 Nov; 9(11):1216-21. doi:
10.1111/j.1365-3156.2004.01330.x. [PMID: 15548319] - Ulisses Carlos Peloso, José Celso Rodrigues De Souza, Marco Aurelio Botino, Aroldo Miniti. Penicillin concentrations in sera and tonsils after intramuscular administration of benzathine penicillin G to children.
The Pediatric infectious disease journal.
2003 Dec; 22(12):1075-8. doi:
10.1097/01.inf.0000101476.65430.f8. [PMID: 14688568] - J Christopher Carey. Congenital syphilis in the 21st century.
Current women's health reports.
2003 Aug; 3(4):299-302. doi:
NULL. [PMID: 12844452] - G de Noray, C Capuano, M Abel. [Campaign to eradicate yaws on Santo Island, Vanuatu in 2001].
Medecine tropicale : revue du Corps de sante colonial.
2003; 63(2):159-62. doi:
NULL. [PMID: 12910654] - Deborah Watson-Jones, Balthazar Gumodoka, Helen Weiss, John Changalucha, James Todd, Kokungoza Mugeye, Anne Buvé, Zephrine Kanga, Leonard Ndeki, Mary Rusizoka, David Ross, Janeth Marealle, Rebecca Balira, David Mabey, Richard Hayes. Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes.
The Journal of infectious diseases.
2002 Oct; 186(7):948-57. doi:
10.1086/342951. [PMID: 12232835] - Christine M Mincham, Donna B Mak, Aileen J Plant. The quality of management of rheumatic fever/ heart disease in the Kimberley.
Australian and New Zealand journal of public health.
2002 Oct; 26(5):417-20. doi:
10.1111/j.1467-842x.2002.tb00340.x. [PMID: 12413284] - Edward W Hook, David H Martin, Joan Stephens, Babara S Smith, Kim Smith. A randomized, comparative pilot study of azithromycin versus benzathine penicillin G for treatment of early syphilis.
Sexually transmitted diseases.
2002 Aug; 29(8):486-90. doi:
10.1097/00007435-200208000-00010. [PMID: 12172535] - B Ranheim, H Ween, A K Egeli, V Hormazabal, M Yndestad, N E Søli. Benzathine penicillin G and procaine penicillin G in piglets: comparison of intramuscular and subcutaneous injection.
Veterinary research communications.
2002 Aug; 26(6):459-65. doi:
10.1023/a:1020590408947. [PMID: 12241099] - Pierre Tattevin, Patrick Renault, Véronique Joly, Rui Bastos, Elisabeth Coelho, Christian Adda, Anne Ebel, Patrick Yeni. Treatment of latent syphilis in HIV-infected patients with 10 d of benzylpenicillin G benethamine: a prospective study in Maputo, Mozambique.
Scandinavian journal of infectious diseases.
2002; 34(4):257-61. doi:
10.1080/00365540110077380. [PMID: 12064687] - M Berthier, D Bonneau, P Mura, A Piriou, D Oriot. Benzathine as a cause for a false-positive test result for amphetamines.
The Journal of pediatrics.
1995 Oct; 127(4):669-70. doi:
10.1016/s0022-3476(95)70143-5. [PMID: 7562302] - N R Badcock, G D Zoanetti. Benzathine interference in the EMIT-st urine amphetamine assay.
Clinical chemistry.
1987 Jun; 33(6):1080. doi:
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The Journal of international medical research.
1983; 11(6):380-4. doi:
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American journal of diseases of children (1960).
1965 Mar; 109(?):232-7. doi:
10.1001/archpedi.1965.02090020234007. [PMID: 14246070] - M KRAML, L G HUMBER, J DUBUC, R GAUDRY. AGENTS AFFECTING LIPID METABOLISM. 8. N,N'-DIBENZYLETHYLENEDIAMINE, THE KEY TO A NOVEL CLASS OF CHOLESTEROL BIOSYNTHESIS INHIBITORS.
Journal of medicinal chemistry.
1964 Jul; 7(?):500-3. doi:
10.1021/jm00334a022. [PMID: 14221134] - G HITZENBERGER, K H SPITZY. [PHARMACOKINETICS OF PENICILLIN G IN CONVENTIONAL AND EXTREMELY HIGH DOSAGE].
Arzneimittel-Forschung.
1964 Jan; 14(?):19-23. doi:
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Vestnik dermatologii i venerologii.
1963 Jul; 37(?):53-8. doi:
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Il Lattante.
1958 Jan; 29(1):31-45. doi:
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Acta medica Italica di malattie infettive e parassitarie.
1954 Dec; 9(12):316-20. doi:
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