Gallopamil hydrochloride (BioDeep_00000660382)

   


代谢物信息卡片


Gallopamil hydrochloride

化学式: C28H41ClN2O5 (520.2703846)
中文名称: (±)-Methoxyverapamil (hydrochloride)
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(C)C(CCCN(C)CCC1=CC(=C(C=C1)OC)OC)(C#N)C2=CC(=C(C(=C2)OC)OC)OC.Cl
InChI: 1H

描述信息

C78274 - Agent Affecting Cardiovascular System > C270 - Antihypertensive Agent > C333 - Calcium Channel Blocker
D002317 - Cardiovascular Agents > D002121 - Calcium Channel Blockers
D000077264 - Calcium-Regulating Hormones and Agents
D049990 - Membrane Transport Modulators
C93038 - Cation Channel Blocker

同义名列表

1 个代谢物同义名

Gallopamil hydrochloride



数据库引用编号

6 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Thibaud R Geoffroy, Naamwin R Meda, Tatjana Stevanovic. Suitability of DPPH spiking for antioxidant screening in natural products: the example of galloyl derivatives from red maple bark extract. Analytical and bioanalytical chemistry. 2017 Sep; 409(22):5225-5237. doi: 10.1007/s00216-017-0465-9. [PMID: 28687878]
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  • Paul Wilhelm Dierkes, Verena Wende, Peter Hochstrate, Wolf-Rüdiger Schlue. L-type Ca2+ channel antagonists block voltage-dependent Ca2+ channels in identified leech neurons. Brain research. 2004 Jul; 1013(2):159-67. doi: 10.1016/j.brainres.2004.03.038. [PMID: 15193524]
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  • Wayne M Mullett, Markus Walles, Karsten Levsen, Jürgen Borlak, Janusz Pawliszyn. Multidimensional on-line sample preparation of verapamil and its metabolites by a molecularly imprinted polymer coupled to liquid chromatography-mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2004 Mar; 801(2):297-306. doi: 10.1016/j.jchromb.2003.11.041. [PMID: 14751799]
  • Jan Gossmann, U Mondorf, A Dietz, W Kramer, H-G Kachel, H Geiger, E-H Scheuermann. A randomized prospective double-blind placebo-controlled study of gallopamil, calcium antagonist of the verapamil type, in stable cyclosporine-treated renal transplant recipients. Transplantation proceedings. 2002 Aug; 34(5):1767-70. doi: 10.1016/s0041-1345(02)03059-2. [PMID: 12176568]
  • T Buzinkaiová, J Polonský, I Skacáni. Determination of fendiline and gallopamil by capillary isotachophoresis. Journal of chromatography. B, Biomedical sciences and applications. 2001 Jun; 757(2):215-20. doi: 10.1016/s0378-4347(01)00146-3. [PMID: 11417865]
  • H J Han, Y H Lee, S H Park. Estradiol-17beta-BSA stimulates Ca(2+) uptake through nongenomic pathways in primary rabbit kidney proximal tubule cells: involvement of cAMP and PKC. Journal of cellular physiology. 2000 Apr; 183(1):37-44. doi: 10.1002/(sici)1097-4652(200004)183:1<37::aid-jcp5>3.0.co;2-n. [PMID: 10699964]
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  • R G Ketelhut, F H Messerli, C Losem, E D Frohlich, L Michalewicz. Systemic and regional hemodynamic effects of gallopamil in patients with essential hypertension. Cardiovascular drugs and therapy. 1997 Mar; 11(1):39-42. doi: 10.1023/a:1007743705737. [PMID: 9140676]
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  • R Kern. Internally standardized simultaneous assay of gallopamil enantiomers in human plasma by means of high performance liquid chromatography. Methods and findings in experimental and clinical pharmacology. 1996 May; 18(4):279-85. doi: NULL. [PMID: 8803960]
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  • C Di Mario, A Iavernaro, F Cucchini. Acute effects of gallopamil on left ventricular systolic and diastolic function in patients with ischaemic heart disease. European heart journal. 1991 Sep; 12(9):1006-11. doi: 10.1093/eurheartj/12.9.1006. [PMID: 1936000]
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