Puromycin aminonucleoside (BioDeep_00000659515)
代谢物信息卡片
Stylomycin aminonucleoside
化学式: C12H18N6O3 (294.1440318)
中文名称: 维生素E醋酸酯
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CN(C)C1=NC=NC2=C1N=CN2C3C(C(C(O3)CO)N)O
InChI: InChI=1S/C12H18N6O3/c1-17(2)10-8-11(15-4-14-10)18(5-16-8)12-9(20)7(13)6(3-19)21-12/h4-7,9,12,19-20H,3,13H2,1-2H3/t6-,7-,9-,12-/m1/s1
描述信息
D009676 - Noxae > D000963 - Antimetabolites
D000970 - Antineoplastic Agents
Puromycin aminonucleoside (NSC 3056) is the aminonucleoside portion of the antibiotic puromycin, and used in nephrosis animal models[1]. Puromycin aminonucleoside induces apoptosis[2]. Puromycin aminonucleoside is a reversible inhibitor of dipeptidyl peptidase II and cytosol alanyl aminopeptidase[3]. Puromycin aminonucleoside induces secretion of cell migrasome[4].
同义名列表
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:42839
- PubChem: 6020
- ChEMBL: CHEMBL1233071
- MeSH: Puromycin Aminonucleoside
- CAS: 58-60-6
- medchemexpress: HY-15695
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
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文献列表
- Chunli Long, Qiang Lin, Junlin Mo, Yangping Xiao, Yongxiang Xie. Hirudin attenuates puromycin aminonucleoside-induced glomerular podocyte injury by inhibiting MAPK-mediated endoplasmic reticulum stress.
Drug development research.
2022 06; 83(4):1047-1056. doi:
10.1002/ddr.21932. [PMID: 35277865] - Hyeon Kyoung Lee, Youn Jae Jang, Se Won Na, Hye Yoom Kim, Byung Hyuk Han, Yun Jung Lee, Ho Sub Lee, Jung Joo Yoon, Dae Gill Kang. Sinkihwan-gamibang ameliorates puromycin aminonucleoside-induced nephrotic syndrome.
Chinese journal of natural medicines.
2022 Mar; 20(3):177-184. doi:
10.1016/s1875-5364(22)60142-0. [PMID: 35369961] - Lisa Nguyen, Wasco Wruck, Lars Erichsen, Nina Graffmann, James Adjaye. The Nephrotoxin Puromycin Aminonucleoside Induces Injury in Kidney Organoids Differentiated from Induced Pluripotent Stem Cells.
Cells.
2022 02; 11(4):. doi:
10.3390/cells11040635. [PMID: 35203286] - Jing Liu, Elaine L Shelton, Rachelle Crescenzi, Daniel C Colvin, Annet Kirabo, Jianyong Zhong, Eric J Delpire, Hai-Chun Yang, Valentina Kon. Kidney Injury Causes Accumulation of Renal Sodium That Modulates Renal Lymphatic Dynamics.
International journal of molecular sciences.
2022 Jan; 23(3):. doi:
10.3390/ijms23031428. [PMID: 35163352] - Saaya Hatakeyama, Akihiro Tojo, Hiroshi Satonaka, Nami O Yamada, Takao Senda, Toshihiko Ishimitsu. Decreased Podocyte Vesicle Transcytosis and Albuminuria in APC C-Terminal Deficiency Mice with Puromycin-Induced Nephrotic Syndrome.
International journal of molecular sciences.
2021 Dec; 22(24):. doi:
10.3390/ijms222413412. [PMID: 34948207] - Xinli Han, Qianying Lv, Haimei Liu, Rufeng Dai, Jiaojiao Liu, Qian Shen, Li Sun, Jia Rao, Jing Chen, Yihui Zhai, Hong Xu. PPARα agonist exerts protective effects in podocyte injury via inhibition of the ANGPTL3 pathway.
Experimental cell research.
2021 10; 407(2):112753. doi:
10.1016/j.yexcr.2021.112753. [PMID: 34499887] - Shivangi Agarwal, Kwi Hye Koh, Nicholas J Tardi, Chuang Chen, Ranadheer Reddy Dande, Joao Pedro WerneckdeCastro, Yashwanth Reddy Sudhini, Cristina Luongo, Domenico Salvatore, Beata Samelko, Mehmet M Altintas, Steve Mangos, Antonio Bianco, Jochen Reiser. Deiodinase-3 is a thyrostat to regulate podocyte homeostasis.
EBioMedicine.
2021 Oct; 72(?):103617. doi:
10.1016/j.ebiom.2021.103617. [PMID: 34649077] - Xia Qiu, Jie Huo, Shiguo Xia, Wenjuan Zhao, Yan Luo, Yunfeng Xia. Dysfunction of the Klotho-miR-30s/TRPC6 axis confers podocyte injury.
Biochemical and biophysical research communications.
2021 06; 557(?):90-96. doi:
10.1016/j.bbrc.2021.04.003. [PMID: 33862465] - Chao-Jun Qi, Yan Pan, Jian-Xiao Shen, Qiao-Lin Kuai, Jin-Xin Zhu, Wan-Peng Wang. Inhibition of microRNA-130b Alleviated Podocyte Injury Induced by Puromycin Aminonucleoside in vitro.
Annals of clinical and laboratory science.
2021 May; 51(3):393-399. doi:
. [PMID: 34162570] - Marc A Egerman, Jenny S Wong, Tian Runxia, Gohar Mosoyan, Kinsuk Chauhan, Joselyn Reyes-Bahamonde, Nanditha Anandakrishnan, Nicholas J Wong, Emilia Bagiella, Fadi Salem, Kristin Meliambro, Hong Li, Evren U Azeloglu, Steven G Coca, Kirk N Campbell, Leopoldo Raij. Plasminogenuria is associated with podocyte injury, edema, and kidney dysfunction in incident glomerular disease.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2020 12; 34(12):16191-16204. doi:
10.1096/fj.202000413r. [PMID: 33070369] - Xiujin Shen, Ying Zhang, Chuan Lin, Chunhua Weng, Yucheng Wang, Shi Feng, Cuili Wang, Xue Shao, Weiqiang Lin, Bingjue Li, Haibing Wang, Jianghua Chen, Hong Jiang. Calcineurin inhibitors ameliorate PAN-induced podocyte injury through the NFAT-Angptl4 pathway.
The Journal of pathology.
2020 11; 252(3):227-238. doi:
10.1002/path.5512. [PMID: 32686149] - Sugimoto Keisuke, Miyazaki Kohei, Enya Takuji, Miyazawa Tomoki, Morimoto Yuichi, Oshima Rina, Takemura Tsukasa, Okada Mitsuru. Role of cathepsin L in idiopathic nephrotic syndrome in children.
Medical hypotheses.
2020 Aug; 141(?):109718. doi:
10.1016/j.mehy.2020.109718. [PMID: 32289645] - Ahmed Abdeen, Hiroko Sonoda, Ayaha Kaito, Sayaka Oshikawa-Hori, Naruki Fujimoto, Masahiro Ikeda. Decreased Excretion of Urinary Exosomal Aquaporin-2 in a Puromycin Aminonucleoside-Induced Nephrotic Syndrome Model.
International journal of molecular sciences.
2020 Jun; 21(12):. doi:
10.3390/ijms21124288. [PMID: 32560242] - Kyle Hayes, Elizabeth Warner, Chris Bollinger, Dale Wright, Richard M Fitch. Repository corticotropin injection versus corticosteroids for protection against renal damage in a focal segmental glomerulosclerosis rodent model.
BMC nephrology.
2020 06; 21(1):226. doi:
10.1186/s12882-020-01879-6. [PMID: 32539845] - Ido Refaeli, Michael R Hughes, Alvin Ka-Wai Wong, Mei Lin Z Bissonnette, Calvin D Roskelley, A Wayne Vogl, Sean J Barbour, Benjamin S Freedman, Kelly M McNagny. Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease.
Scientific reports.
2020 06; 10(1):9419. doi:
10.1038/s41598-020-64907-3. [PMID: 32523052] - Yuko Fujii, Hideki Matsumura, Satoshi Yamazaki, Akihiko Shirasu, Hyogo Nakakura, Tohru Ogihara, Akira Ashida. Efficacy of a mitochondrion-targeting agent for reducing the level of urinary protein in rats with puromycin aminonucleoside-induced minimal-change nephrotic syndrome.
PloS one.
2020; 15(1):e0227414. doi:
10.1371/journal.pone.0227414. [PMID: 31905213] - Ashish K Solanki, Pankaj Srivastava, Bushra Rahman, Joshua H Lipschutz, Deepak Nihalani, Ehtesham Arif. The Use of High-Throughput Transcriptomics to Identify Pathways with Therapeutic Significance in Podocytes.
International journal of molecular sciences.
2019 Dec; 21(1):. doi:
10.3390/ijms21010274. [PMID: 31906131] - Felipe Mateus Ornellas, Rodrigo J Ramalho, Camilla Fanelli, Margoth Ramos Garnica, Denise M A C Malheiros, Sabrina Vargas Martini, Marcelo Marcos Morales, Irene L Noronha. Mesenchymal Stromal Cells Induce Podocyte Protection in the Puromycin Injury Model.
Scientific reports.
2019 12; 9(1):19604. doi:
10.1038/s41598-019-55284-7. [PMID: 31862892] - Rikke Ydegaard, Per Svenningsen, Claus Bistrup, Rene Frydensbjerg Andersen, Jane Stubbe, Kristian Bergholt Buhl, Niels Marcussen, Gitte Rye Hinrichs, Hiba Iraqi, Reza Zamani, Henrik Dimke, Boye L Jensen. Nephrotic syndrome is associated with increased plasma K+ concentration, intestinal K+ losses, and attenuated urinary K+ excretion: a study in rats and humans.
American journal of physiology. Renal physiology.
2019 12; 317(6):F1549-F1562. doi:
10.1152/ajprenal.00179.2019. [PMID: 31566427] - Érika B Rangel, Samirah A Gomes, Rosemeire Kanashiro-Takeuchi, Joshua M Hare. Progenitor/Stem Cell Delivery by Suprarenal Aorta Route in Acute Kidney Injury.
Cell transplantation.
2019 11; 28(11):1390-1403. doi:
10.1177/0963689719860826. [PMID: 31409111] - Xiuwen Zhai, Ling Wang, Chen Xu, Qing Hou, Liwen Zhang, Zhi Li, Weisong Qin, Zhihong Liu, Zhaohong Chen. Triptolide preserves glomerular barrier function via the inhibition of p53-mediated increase of GADD45B.
Archives of biochemistry and biophysics.
2019 08; 671(?):210-217. doi:
10.1016/j.abb.2019.07.012. [PMID: 31330131] - Yohei Tsuchida, Jianyong Zhong, Tadashi Otsuka, Anna Dikalova, Ira Pastan, G M Anantharamaiah, MacRae F Linton, Patricia G Yancey, T Alp Ikizler, Agnes B Fogo, Haichun Yang, Valentina Kon. Lipoprotein modulation of proteinuric renal injury.
Laboratory investigation; a journal of technical methods and pathology.
2019 07; 99(8):1107-1116. doi:
10.1038/s41374-019-0253-6. [PMID: 31019291] - Aya Horikawa, Tomomi Yoneda, Eishin Yaoita, Katsushi Yamaguchi, Shuji Shigenobu, Mizuki Kuramochi, Jyoji Yamate, Takashi Inui, Osamu Ishibashi. A novel splicing variant of small nucleolar RNA host gene 4 is a podocyte-selective non-coding RNA upregulated in response to puromycin aminonucleoside-induced podocyte injury.
Journal of biochemistry.
2019 May; 165(5):447-454. doi:
10.1093/jb/mvy118. [PMID: 30597036] - Wei Gong, Jiayu Song, Xi Chen, Shuzhen Li, Jing Yu, Weiwei Xia, Guixia Ding, Yue Zhang, Zhanjun Jia, Aihua Zhang, Songming Huang. Estrogen-related receptor-α mediates puromycin aminonucleoside-induced mesangial cell apoptosis and inflammatory injury.
American journal of physiology. Renal physiology.
2019 05; 316(5):F906-F913. doi:
10.1152/ajprenal.00507.2018. [PMID: 30698047] - Limin Li, Ying Liu, Shan Li, Rong Yang, Caihong Zeng, Weiwei Rong, Hongwei Liang, Mingchao Zhang, Xiaodong Zhu, Koby Kidder, Yuan Liu, Zhihong Liu, Ke Zen. Signal regulatory protein α protects podocytes through promoting autophagic activity.
JCI insight.
2019 03; 5(?):. doi:
10.1172/jci.insight.124747. [PMID: 30888336] - Yi-Qi Yang, Jian Liang, Xiao-Dong Han, Rui-Min Tian, Xu-Sheng Liu, Wei Mao, Hong-Tao Xu, Bo Liu, Peng Xu. Dual-function of triptriolide in podocytes injury: inhibiting of apoptosis and restoring of survival.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2019 Jan; 109(?):1932-1939. doi:
10.1016/j.biopha.2018.11.031. [PMID: 30551448] - Sei Yonezawa, Mizuho Abe, Yasushi Kawasaki, Yasuhiro Natori, Akinori Sugiyama. Each liver X receptor (LXR) type has a different purpose in different situations.
Biochemical and biophysical research communications.
2019 01; 508(1):92-96. doi:
10.1016/j.bbrc.2018.11.076. [PMID: 30471864] - Takahito Moriyama, Kazunori Karasawa, Fumio Hasegawa, Keiko Uchida, Kosaku Nitta. Sertraline Reduces Albuminuria by Interfering with Caveolae-Mediated Endocytosis through Glomerular Endothelial and Epithelial Cells.
American journal of nephrology.
2019; 50(6):444-453. doi:
10.1159/000503917. [PMID: 31655808] - Ayano Kubo, Isao Shirato, Teruo Hidaka, Miyuki Takagi, Yu Sasaki, Katsuhiko Asanuma, Kazumi Ishidoh, Yusuke Suzuki. Expression of Cathepsin L and Its Intrinsic Inhibitors in Glomeruli of Rats With Puromycin Aminonucleoside Nephrosis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
2018 12; 66(12):863-877. doi:
10.1369/0022155418791822. [PMID: 30052474] - Zuokang Zheng, Hong Hu, Yanrong Tong, Zhixia Hu, Shiyu Cao, Ce Shan, Wenhe Lin, Yike Yin, Zhonghan Li. MiR-27b regulates podocyte survival through targeting adenosine receptor 2B in podocytes from non-human primate.
Cell death & disease.
2018 11; 9(11):1133. doi:
10.1038/s41419-018-1178-5. [PMID: 30429458] - Erika B Rangel, Samirah A Gomes, Rosemeire Kanashiro-Takeuchi, Russell G Saltzman, Changli Wei, Phillip Ruiz, Jochen Reiser, Joshua M Hare. Kidney-derived c-kit+ progenitor/stem cells contribute to podocyte recovery in a model of acute proteinuria.
Scientific reports.
2018 10; 8(1):14723. doi:
10.1038/s41598-018-33082-x. [PMID: 30283057] - Halil İbrahim Saygı, Zeynep Banu Güngör, Fatma Kalay, İsmail Seçkin. In glomerular cells of puromycin aminonucleoside nephrosis rats both phosphorylated and total STAT3 levels increased during proteinuria.
Acta histochemica.
2018 Aug; 120(6):595-603. doi:
10.1016/j.acthis.2018.07.005. [PMID: 30054017] - Alessandra Stacchiotti, Gaia Favero, Antonio Lavazza, Maria Monsalve, Luigi Fabrizio Rodella, Rita Rezzani. Taurine Supplementation Alleviates Puromycin Aminonucleoside Damage by Modulating Endoplasmic Reticulum Stress and Mitochondrial-Related Apoptosis in Rat Kidney.
Nutrients.
2018 May; 10(6):. doi:
10.3390/nu10060689. [PMID: 29843457] - Jiro Kino, Shoji Tsuji, Tetsuya Kitao, Yuko Akagawa, Sohsaku Yamanouchi, Takahisa Kimata, Kazunari Kaneko. Antiproteinuric effect of an endothelin-1 receptor antagonist in puromycin aminonucleoside-induced nephrosis in rat.
Pediatric research.
2018 05; 83(5):1041-1048. doi:
10.1038/pr.2018.11. [PMID: 29360807] - Xiaojing Nie, Melinda A Chanley, Ruma Pengal, David B Thomas, Shipra Agrawal, William E Smoyer. Pharmacological and genetic inhibition of downstream targets of p38 MAPK in experimental nephrotic syndrome.
American journal of physiology. Renal physiology.
2018 04; 314(4):F602-F613. doi:
10.1152/ajprenal.00207.2017. [PMID: 29187369] - Li-Qin Peng, Hong Zhao, Song Liu, Ya-Pei Yuan, Cheng-Yan Yuan, Mercy-Julian Mwamunyi, David Pearce, Li-Jun Yao. Lack of serum- and glucocorticoid-inducible kinase 3 leads to podocyte dysfunction.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
2018 02; 32(2):576-587. doi:
10.1096/fj.201700393rr. [PMID: 28935820] - Fernandes-Cerqueira Cátia, Quelhas-Santos Janete, Sampaio-Maia Benedita, Simões-Silva Liliana, Soares-Silva Isabel, Roncon-Albuquerque Roberto, Pestana Manuel. Calcitriol Prevents Cardiovascular Repercussions in Puromycin Aminonucleoside-Induced Nephrotic Syndrome.
BioMed research international.
2018; 2018(?):3609645. doi:
10.1155/2018/3609645. [PMID: 29607318] - Kaiyue Zhang, Wenjuan Sun, Lai Zhang, Xuefang Xu, Jidong Wang, Yan Hong. miR-499 Ameliorates Podocyte Injury by Targeting Calcineurin in Minimal Change Disease.
American journal of nephrology.
2018; 47(2):94-102. doi:
10.1159/000486967. [PMID: 29448244] - Takahito Moriyama, Kayo Sasaki, Kazunori Karasawa, Keiko Uchida, Kosaku Nitta. Intracellular transcytosis of albumin in glomerular endothelial cells after endocytosis through caveolae.
Journal of cellular physiology.
2017 Dec; 232(12):3565-3573. doi:
10.1002/jcp.25817. [PMID: 28112392] - Yosuke Kawamorita, Takeshi Shiraishi, Yoshifuru Tamura, Takanori Kumagai, Shigeru Shibata, Yoshihide Fujigaki, Makoto Hosoyamada, Takahiko Nakagawa, Shunya Uchida. Renoprotective effect of topiroxostat via antioxidant activity in puromycin aminonucleoside nephrosis rats.
Physiological reports.
2017 Aug; 5(15):. doi:
10.14814/phy2.13358. [PMID: 28774949] - Nan Dong, Lixia Meng, Ruqun Xue, Meng Yu, Zhonghua Zhao, Xueguang Liu. Adrenomedullin ameliorates podocyte injury induced by puromycin aminonucleoside in vitro and in vivo through modulation of Rho GTPases.
International urology and nephrology.
2017 Aug; 49(8):1489-1506. doi:
10.1007/s11255-017-1622-y. [PMID: 28528353] - Akihiro Tojo, Saaya Hatakeyama, Satoshi Kinugasa, Satoru Fukuda, Toshio Sakai. Enhanced podocyte vesicle transport in the nephrotic rat.
Medical molecular morphology.
2017 Jun; 50(2):86-93. doi:
10.1007/s00795-016-0151-6. [PMID: 28314927] - Min Chul Kho, Ji Hun Park, Byung Hyuk Han, Rui Tan, Jung Joo Yoon, Hye Yoom Kim, You Mee Ahn, Yun Jung Lee, Dae Gill Kang, Ho Sub Lee. Plantago asiatica L. Ameliorates Puromycin Aminonucleoside-Induced Nephrotic Syndrome by Suppressing Inflammation and Apoptosis.
Nutrients.
2017 Apr; 9(4):. doi:
10.3390/nu9040386. [PMID: 28420111] - Markus M Rinschen, Florian Grahammer, Ann-Kathrin Hoppe, Priyanka Kohli, Henning Hagmann, Oliver Kretz, Sabine Bertsch, Martin Höhne, Heike Göbel, Malte P Bartram, Rajesh Kumar Gandhirajan, Marcus Krüger, Paul-Thomas Brinkkoetter, Tobias B Huber, Martin Kann, Sara A Wickström, Thomas Benzing, Bernhard Schermer. YAP-mediated mechanotransduction determines the podocyte's response to damage.
Science signaling.
2017 Apr; 10(474):. doi:
10.1126/scisignal.aaf8165. [PMID: 28400537] - Lin Wu, Mingyu Chen, Huijuan Mao, Ningning Wang, Bo Zhang, Xiufen Zhao, Jun Qian, Changying Xing. Albumin-based nanoparticles as methylprednisolone carriers for targeted delivery towards the neonatal Fc receptor in glomerular podocytes.
International journal of molecular medicine.
2017 Apr; 39(4):851-860. doi:
10.3892/ijmm.2017.2902. [PMID: 28259932] - Yi Chen, Jun Chen, Jianxin Wan, Na Gao, Jiong Cui, Danyu You, Zhenhuan Zou. Bone marrow-derived mesenchymal stem cells ameliorate nephrosis through repair of impaired podocytes.
Clinical and investigative medicine. Medecine clinique et experimentale.
2017 02; 40(1):E13-E24. doi:
10.25011/cim.v40i1.28050. [PMID: 28218578] - İsmail Seçkin, Mümin Uzunalan, Meltem Pekpak, Sibel Köktürk, Hüseyin Avni Sönmez, Zeynep Banu Güngör, Özgür Doğuş Demirkiran, Halil İbrahim Saygi, Elif Yaprak Saraç. The relationship between glomerular function and podocyte structure of pre-proteinuria and acute nephrosis in puromycin aminonucleoside-induced rat models: a comparative electron microscopic study.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie.
2017; 58(3):823-830. doi:
NULL. [PMID: 29250660] - Hiroshi Uchino, Junko Fujishima, Kaori Fukuoka, Teppei Iwakiri, Akira Kamikuri, Hidenori Maeda, Kazuhiro Nakama. Usefulness of urinary biomarkers for nephrotoxicity in cynomolgus monkeys treated with gentamicin, cisplatin, and puromycin aminonucleoside.
The Journal of toxicological sciences.
2017; 42(5):629-640. doi:
10.2131/jts.42.629. [PMID: 28904298] - Frances Kindt, Elke Hammer, Stefan Kemnitz, Antje Blumenthal, Paul Klemm, Rabea Schlüter, Susan E Quaggin, Jens van den Brandt, Georg Fuellen, Uwe Völker, Karlhans Endlich, Nicole Endlich. A novel assay to assess the effect of pharmaceutical compounds on the differentiation of podocytes.
British journal of pharmacology.
2017 01; 174(2):163-176. doi:
10.1111/bph.13667. [PMID: 27858997] - Michal Herman-Edelstein, Avry Chagnac, Zvi Nevo, Ehud Skutelsky, Yoav Evron, Yehudit Hirsch, Lya Ben-Dor, Idit Schwartz, Doron Schwartz, Talia Weinstein. Angiotensin converting-enzyme inhibition restores glomerular glycosaminoglycans in rat puromycin nephrosis.
Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie.
2016 Nov; 68(10):543-552. doi:
10.1016/j.etp.2016.08.004. [PMID: 27591087] - Chang Z Zhu, Sujatha Gopalakrishnan, Kelly Doyle, Arthur L Nikkel, Lauren Olson, Vivek C Abraham, Laura Leys, Deborah Widomski, Katherine Salte, Brent Putman, Steve Pratt, Ji Ma, Zhi Su, Murali Gopalakrishnan, Chih-Hung Lee, Steve P McGaraughty. A-306989, an inhibitor of adenosine kinase, is renoprotective in rodent models of podocyte, basement membrane, and obstructive injury.
European journal of pharmacology.
2016 Oct; 788(?):1-11. doi:
10.1016/j.ejphar.2016.06.012. [PMID: 27288879] - Yusuke Wada, Masaki Abe, Hiroshi Moritani, Hikaru Mitori, Mitsuhiro Kondo, Keiko Tanaka-Amino, Megumi Eguchi, Akira Imasato, Yutaka Inoki, Hiroshi Kajiyama, Toshihide Mimura, Yuichi Tomura. Original Research: Potential of urinary nephrin as a biomarker reflecting podocyte dysfunction in various kidney disease models.
Experimental biology and medicine (Maywood, N.J.).
2016 10; 241(16):1865-76. doi:
10.1177/1535370216651937. [PMID: 27216597] - Xiujin Shen, Hong Jiang, Meike Ying, Zhoutao Xie, Xiayu Li, Haibing Wang, Jie Zhao, Chuan Lin, Yucheng Wang, Shi Feng, Jia Shen, Chunhua Weng, Weiqiang Lin, Huiping Wang, Qin Zhou, Yan Bi, Meng Li, Lingyan Wang, Tongyu Zhu, Xiaoru Huang, Hui-Yao Lan, Jing Zhou, Jianghua Chen. Calcineurin inhibitors cyclosporin A and tacrolimus protect against podocyte injury induced by puromycin aminonucleoside in rodent models.
Scientific reports.
2016 09; 6(?):32087. doi:
10.1038/srep32087. [PMID: 27580845] - Yanggang Yuan, Chuanyan Zhao, Xiaofei An, Lin Wu, Hui Wang, Min Zhao, Mi Bai, Suyan Duan, Bo Zhang, Aihua Zhang, Changying Xing. A vital role for myosin-9 in puromycin aminonucleoside-induced podocyte injury by affecting actin cytoskeleton.
Free radical research.
2016 Jun; 50(6):627-37. doi:
10.3109/10715762.2016.1155706. [PMID: 26902808] - Khalil Udwan, Gaëlle Brideau, Marc Fila, Aurélie Edwards, Bruno Vogt, Alain Doucet. Oxidative Stress and Nuclear Factor κB (NF-κB) Increase Peritoneal Filtration and Contribute to Ascites Formation in Nephrotic Syndrome.
The Journal of biological chemistry.
2016 May; 291(21):11105-13. doi:
10.1074/jbc.m116.724690. [PMID: 27033704] - S Agrawal, M A Chanley, D Westbrook, X Nie, T Kitao, A J Guess, R Benndorf, G Hidalgo, W E Smoyer. Pioglitazone Enhances the Beneficial Effects of Glucocorticoids in Experimental Nephrotic Syndrome.
Scientific reports.
2016 05; 6(?):24392. doi:
10.1038/srep24392. [PMID: 27142691] - Wen-wen Qiu, Jun Yuan, Liu Yang. [Effect of Wenyang Huoxue Lishul Recipe Containing Serum on Expression of Cathepsin L in Puromycin Aminonucleoside-induced Injury of Mouse Glomerular Podocytes].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
2016 May; 36(5):602-7. doi:
. [PMID: 27386655] - Xuejuan Li, Fangrui Ding, Xiaoyan Zhang, Baihong Li, Jie Ding. The Expression Profile of Complement Components in Podocytes.
International journal of molecular sciences.
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