Doxantrazole (BioDeep_00000656348)

   


代谢物信息卡片


9H-Thioxanthen-9-one,3-(2H-tetrazol-5-yl)-, 10,10-dioxide

化学式: C14H8N4O3S (312.03170980000004)
中文名称: 3-(1H-四唑-5-基)-9H-噻吨-9-酮 10,10-二氧化物
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: C1=CC=C2C(=C1)C(=O)C3=C(S2(=O)=O)C=C(C=C3)C4=NNN=N4
InChI: InChI=1S/C14H8N4O3S/c19-13-9-3-1-2-4-11(9)22(20,21)12-7-8(5-6-10(12)13)14-15-17-18-16-14/h1-7H,(H,15,16,17,18)

描述信息

D019141 - Respiratory System Agents > D018927 - Anti-Asthmatic Agents > D001993 - Bronchodilator Agents
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D004791 - Enzyme Inhibitors > D010726 - Phosphodiesterase Inhibitors

同义名列表

2 个代谢物同义名

9H-Thioxanthen-9-one,3-(2H-tetrazol-5-yl)-, 10,10-dioxide; Doxantrazole



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Laurent Ferrier, Claudine Serradeil-Le Gal, Anke M Schulte, Valentina Vasina, Eric Gaultier, Silke Schroedel, Maria Grazia Ursino, Gilles Chaumaz, Marc Pascal, Fabrizio De Ponti, Lionel Bueno. Proinflammatory role of vasopressin through V1b receptors in hapten-induced experimental colitis in rodents: implication in IBD. American journal of physiology. Gastrointestinal and liver physiology. 2010 Dec; 299(6):G1298-307. doi: 10.1152/ajpgi.00022.2010. [PMID: 20864658]
  • Laura Ramos, Geber Peña, Bolin Cai, E A Deitch, Luis Ulloa. Mast cell stabilization improves survival by preventing apoptosis in sepsis. Journal of immunology (Baltimore, Md. : 1950). 2010 Jul; 185(1):709-16. doi: 10.4049/jimmunol.1000273. [PMID: 20519642]
  • Laurent Ferrier, Florian Bérard, Laurent Debrauwer, Chantal Chabo, Philippe Langella, Lionel Buéno, Jean Fioramonti. Impairment of the intestinal barrier by ethanol involves enteric microflora and mast cell activation in rodents. The American journal of pathology. 2006 Apr; 168(4):1148-54. doi: 10.2353/ajpath.2006.050617. [PMID: 16565490]
  • Muriel Larauche, Lionel Buéno, Jean Fioramonti. Effect of dietary nitric oxide on gastric mucosal mast cells in absence or presence of an experimental gastritis in rats. Life sciences. 2003 Aug; 73(12):1505-16. doi: 10.1016/s0024-3205(03)00480-6. [PMID: 12865090]
  • A D Kraneveld, T Muis, A S Koster, F P Nijkamp. Role of mucosal mast cells in early vascular permeability changes of intestinal DTH reaction in the rat. The American journal of physiology. 1998 05; 274(5):G832-9. doi: 10.1152/ajpgi.1998.274.5.g832. [PMID: 9612263]
  • M Miampamba, D T Tan, M R Oliver, K A Sharkey, R B Scott. Intestinal anaphylaxis induces Fos immunoreactivity in myenteric plexus of rat small intestine. The American journal of physiology. 1997 Jan; 272(1 Pt 1):G181-9. doi: 10.1152/ajpgi.1997.272.1.g181. [PMID: 9038892]
  • M W Turner, P Boulton, S Strobel. Experimental intestinal hypersensitivity. Effect of four anti-allergic drugs on protein uptake, permeability to sugars and mucosal mast-cell activation. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 1995 May; 25(5):448-55. doi: 10.1111/j.1365-2222.1995.tb01076.x. [PMID: 7553248]
  • M H Perdue, D G Gall. Intestinal anaphylaxis in the rat: jejunal response to in vitro antigen exposure. The American journal of physiology. 1986 Apr; 250(4 Pt 1):G427-31. doi: 10.1152/ajpgi.1986.250.4.g427. [PMID: 3008574]
  • M H Perdue, D G Gall. Transport abnormalities during intestinal anaphylaxis in the rat: effect of antiallergic agents. The Journal of allergy and clinical immunology. 1985 Sep; 76(3):498-503. doi: 10.1016/0091-6749(85)90733-x. [PMID: 2863297]
  • V Holford-Strevens. Desensitization of rat mast cells: studies of some effects of anti-allergic drugs. Agents and actions. 1984 Jun; 14(5-6):643-8. doi: 10.1007/bf01978901. [PMID: 6206698]
  • H Jones, A Bye. Correlation of bioavailability in man with simulated absorption data for three doxantrazole preparations. The Journal of pharmacy and pharmacology. 1979 Nov; 31(11):730-3. doi: 10.1111/j.2042-7158.1979.tb13646.x. [PMID: 41901]
  • A Bye, G Land. Determination of 3-(5-tetrazolyl) thioxanthone 10,10-dioxide in human plasma, urine and faeces. Journal of chromatography. 1975 Dec; 115(1):93-9. doi: 10.1016/s0021-9673(00)89020-2. [PMID: 420]