2-ethylsulfanyl-1H-benzimidazole (BioDeep_00000653503)

   


代谢物信息卡片


2-Ethylsulfanyl-1H-benzoimidazole

化学式: C9H10N2S (178.0565)
中文名称: 2-(乙基硫代)-(9ci)-1H-苯并咪唑, 2-乙基硫烷基-1H-苯并咪唑
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CCSC1=NC2=CC=CC=C2N1
InChI: InChI=1S/C9H10N2S/c1-2-12-9-10-7-5-3-4-6-8(7)11-9/h3-6H,2H2,1H3,(H,10,11)

描述信息

D002491 - Central Nervous System Agents > D000927 - Anticonvulsants
D020011 - Protective Agents > D000975 - Antioxidants
D007155 - Immunologic Factors

同义名列表

3 个代谢物同义名

2-Ethylsulfanyl-1H-benzoimidazole; 2-ethylsulfanyl-1H-benzimidazole; 2-Ethylsulfanyl-1H-benzoimidazole



数据库引用编号

3 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Daria A Belinskaia, Elena I Savelieva, Georgy V Karakashev, Olga I Orlova, Mikhail A Leninskii, Nataliia S Khlebnikova, Natalia N Shestakova, Alexandra R Kiskina. Investigation of Bemethyl Biotransformation Pathways by Combination of LC-MS/HRMS and In Silico Methods. International journal of molecular sciences. 2021 Aug; 22(16):. doi: 10.3390/ijms22169021. [PMID: 34445727]
  • Dorota Kwiatkowska, Katarzyna Kowalczyk, Krzysztof Grucza, Mirosław Szutowski, Ewa Bulska, Mariola Wicka. Detection of bemitil and its metabolite in urine by means of LC-MS/MS in view of doping control analysis. Drug testing and analysis. 2018 Nov; 10(11-12):1682-1688. doi: 10.1002/dta.2524. [PMID: 30346653]
  • I V Zarubina, P D Shabanov. Antioxidant Effect of Polyoxidonium and Metaprot during Bronchopulmonary Inflammation in Rats. Bulletin of experimental biology and medicine. 2015 Dec; 160(2):234-7. doi: 10.1007/s10517-015-3137-9. [PMID: 26621277]
  • S I Baulin, S M Rogacheva, S V Afanaseva, E V Zabanova, Yu V Karagaycheva. Pharmaceutical Composition for Improving Physical Working Capacity. Bulletin of experimental biology and medicine. 2015 Nov; 160(1):45-8. doi: 10.1007/s10517-015-3094-3. [PMID: 26601841]
  • V V Vorob'eva, I V Zarubina, P D Shabanov. [Protective effects of metaprot and ethomerzol in carbophos intoxications]. Eksperimental'naia i klinicheskaia farmakologiia. 2012; 75(8):25-30. doi: ". [PMID: 23012992]
  • D A Kibal'chich, V G Belolipetskaia, S V Blagodatskikh, S Iu Martsevich, L I Rudenko, V R Iatsuk. [Pharmacokinetics of domestic actoprotector drug Metaprot in healthy volunteers]. Eksperimental'naia i klinicheskaia farmakologiia. 2011; 74(6):30-2. doi: NULL. [PMID: 21870773]
  • V E Novikov, N S Ponamareva. [Effect of aminothiol anthihypoxants on hydration and peroxidation processes in traumatic brain injury]. Eksperimental'naia i klinicheskaia farmakologiia. 2007 May; 70(3):46-9. doi: ". [PMID: 17650634]
  • S V Oskovityĭ, N N Bezborodkina, I V Zarubina, O P Mironova, B N Kudrivtsev, S N Shulenin. [Studying the hepatoprotector effect of bemithyl on a model of chronic toxic liver damage]. Eksperimental'naia i klinicheskaia farmakologiia. 2006 Mar; 69(2):52-4. doi: ". [PMID: 16845942]
  • I V Zarubina, F N Nurmanbetova, P D Shabanov. Bemithyl potentiates the antioxidant effect of intermittent hypoxic training. Bulletin of experimental biology and medicine. 2005 Aug; 140(2):190-3. doi: 10.1007/s10517-005-0442-8. [PMID: 16282998]
  • I V Zarubina, F N Narmanbetova, E F Agadzhanian, P D Shabanov. [Efficacy of bemithyl and pyrazidol in patients with cerebroasthenia due to brain injury]. Klinicheskaia meditsina. 2005; 83(11):59-62. doi: ". [PMID: 16404942]
  • V A Myshkin, I A Guliaeva, R B Ibatullina, A I Savlukov, D A Enikeev, S A Sergeeva. [The influence of the actoprotectors on lipid peroxidation and erythrocyte membranes in rats poisoned with malathion ]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 2004 Jul; ?(3):10-2. doi: . [PMID: 15446413]
  • I V Zarubina, N A Kuritsyna, P D Shabanov. Cerebroprotective effect of combined treatment with pyrazidol and bemitil in craniocerebral trauma. Bulletin of experimental biology and medicine. 2004 Jul; 138(1):58-62. doi: 10.1023/b:bebm.0000046939.59393.ac. [PMID: 15514724]
  • M V Solov'ev, B I Krivoruchko, I V Zarubina, O P Mironova. [The effect of bemithyl in rats with experimental pneumonia]. Eksperimental'naia i klinicheskaia farmakologiia. 2002 Jul; 65(4):28-9. doi: ". [PMID: 12449071]
  • I V Zarubina, O P Mironova. Antioxidant effects of Bemitil during acute cerebral hypoxia. Bulletin of experimental biology and medicine. 2002 Feb; 133(2):139-40. doi: ". [PMID: 12428282]
  • S N Nagornev, S V Kalinkin, I P Bobrovnitskiĭ, S I Sytnik, T V Petrova, T A Orlova. [Metabolic effects of static physical load under the conditions of pharmakologicheskoĭ mobilization of physical endurance]. Aviakosmicheskaia i ekologicheskaia meditsina = Aerospace and environmental medicine. 2000; 34(5):18-24. doi: ". [PMID: 11816402]
  • T A Lisitsyna, A D Durnev, M M Ivanova, A I Speranskiĭ, S B Seredenin, V A Nasonova. [The effect of bemetil on the production of DNA antibodies in patients with systemic lupus erythematosus]. Eksperimental'naia i klinicheskaia farmakologiia. 1999 Sep; 62(5):38-41. doi: NULL. [PMID: 10572751]
  • M Saitoh, T Umemura, Y Kawasaki, J Momma, Y Matsushima, K Sakemi, K Isama, S Kitajima, Y Ogawa, R Hasegawa, T Suzuki, M Hayashi, T Inoue, Y Ohno, T Sofuni, Y Kurokawa, M Tsuda. Toxicity study of a rubber antioxidant, mixture of 2-mercaptomethylbenzimidazoles, by repeated oral administration to rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 1999 Jul; 37(7):777-87. doi: 10.1016/s0278-6915(99)00058-7. [PMID: 10496380]
  • R E Lakhin, L A Belozerova, V A Maksimets, D M Romanov. [Changes in the oxidant-antioxidant system activity in patients with hepatic failure treated with hyperbaric oxygenation and actoprotectors]. Anesteziologiia i reanimatologiia. 1999 Mar; ?(2):55-8. doi: ". [PMID: 10360076]
  • V P Galantsev, R I Kovalenko, B I Krivoruchko, O V Loshchagin, V A Poleshchuk, A V Smirnov, I N Ianvareva. [Oxygen deficiency tolerance in rodents nonadapted and adapted to water environment]. Zhurnal evoliutsionnoi biokhimii i fiziologii. 1999 Jan; 35(1):43-7. doi: ". [PMID: 10399822]
  • I B Mikhałlov, V I Guzeva, M Ia Sharf, O B Basharina, N A Chałka. [The effect of bemitil on the parameters of lipid peroxidation and nitrogen metabolism in epilepsy in children]. Eksperimental'naia i klinicheskaia farmakologiia. 1997 May; 60(3):20-2. doi: NULL. [PMID: 9324390]
  • A V Smirnov, B I Krivoruchko. [Hypoxia and its pharmacological correction: a key problem of anesthesiology and intensive care]. Anesteziologiia i reanimatologiia. 1997 May; ?(3):97-8. doi: ". [PMID: 9290001]
  • I I Baryshnikov. [Importance of toxicological studies in animals for elaboration of pathogenetic therapy of hydrazine intoxication]. Meditsina truda i promyshlennaia ekologiia. 1997; ?(6):22-5. doi: ". [PMID: 9273132]
  • M B Plotnikov, E A Kobzeva, T M Plotnikova. [Antioxidant effects of antihypoxic drugs in cerebral ischemia]. Biulleten' eksperimental'noi biologii i meditsiny. 1992 May; 113(5):504-6. doi: ". [PMID: 1421270]
  • V S Lobzin, L A Saĭkova, M L Chukhlovina, V G Pustozerov. [The use of bemitil in patients with progressive muscular dystrophies]. Likars'ka sprava. 1992 Apr; ?(4):85-7. doi: ". [PMID: 1441389]
  • L I Ratnikova. [The dynamics of the immunological indices during the treatment of recurrent erysipelas with the new immunostimulant bemitil]. Zhurnal mikrobiologii, epidemiologii i immunobiologii. 1991 Sep; ?(9):56-8. doi: NULL. [PMID: 1759524]
  • V S Lobzin, L A Saĭkova, M L Chukhlovina, V G Pustozerov. [Mechanisms of the therapeutic effect of bemitil in neuromuscular diseases]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). 1991; 91(9):22-4. doi: ". [PMID: 1664607]
  • M B Plotnikov, A S Saratikov, T M Plotnikova, V A Khazanov, O P Panina. [Antihypoxic and antioxidative properties of bemitil]. Biulleten' eksperimental'noi biologii i meditsiny. 1989 May; 107(5):583-5. doi: ". [PMID: 2736293]
  • I I Leshchiniuk, E O Konovalova, A I Kvitchataia, V G Shamraĭ, Iu G Bobkov. [The effect of vestibuloprotectors on the cyclic nucleotide system in experimental motion sickness]. Patologicheskaia fiziologiia i eksperimental'naia terapiia. 1989 Jan; ?(1):26-8. doi: NULL. [PMID: 2785671]
  • S S Boĭko, Iu G Bobkov, V P Zherdev, A A Dvorianinov. [Bemetil pharmacokinetics in an experiment on rats]. Farmakologiia i toksikologiia. 1987 Sep; 50(5):54-6. doi: NULL. [PMID: 3691781]
  • S S Boĭko, Iu G Bobkov, T A Dobrokhotova, N A Kniazeva, G G Neznamov. [Experimental and clinical data on the ability of bemetil to penetrate the hemato-encephalic barrier]. Farmakologiia i toksikologiia. 1987 May; 50(3):79-81. doi: NULL. [PMID: 3609285]