Naxagolide hydrochloride (BioDeep_00000653181)
代谢物信息卡片
ent Naxagolide Hydrochloride
化学式: C15H22ClNO2 (283.1338982)
中文名称: 那高利特盐酸盐
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCCN1CCOC2C1CCC3=C2C=C(C=C3)O.Cl
InChI: /m1./s1
描述信息
C78272 - Agent Affecting Nervous System > C38149 - Antiparkinsonian Agent
同义名列表
数据库引用编号
5 个数据库交叉引用编号
- ChEBI: CHEBI:177381
- PubChem: 57532
- ChEMBL: CHEMBL2106804
- CAS: 100935-99-7
- CAS: 99705-65-4
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Jaleh Varshosaz, Nasser Tavakoli, S Ali Eram. Use of natural gums and cellulose derivatives in production of sustained release metoprolol tablets.
Drug delivery.
2006 Mar; 13(2):113-9. doi:
10.1080/10717540500313356. [PMID: 16423799] - Y S R Krishnaiah, S M Al-Saidan, D V Chandrasekhar, V Satyanarayana. Controlled in vivo release of nicorandil from a carvone-based transdermal therapeutic system in human volunteers.
Drug delivery.
2006 Jan; 13(1):69-77. doi:
10.1080/10717540500309107. [PMID: 16401596] - Fiona J McInnes, Panna Thapa, Alan J Baillie, Peter G Welling, David G Watson, Ian Gibson, Andrea Nolan, Howard N E Stevens. In vivo evaluation of nicotine lyophilised nasal insert in sheep.
International journal of pharmaceutics.
2005 Nov; 304(1-2):72-82. doi:
10.1016/j.ijpharm.2005.07.025. [PMID: 16183221] - E Mehuys, J P Remon, A Korst, L Van Bortel, R Mols, P Augustijns, C Porter, C Vervaet. Human bioavailability of propranolol from a matrix-in-cylinder system with a HPMC-Gelucire core.
Journal of controlled release : official journal of the Controlled Release Society.
2005 Oct; 107(3):523-36. doi:
10.1016/j.jconrel.2005.06.019. [PMID: 16055224] - Ying Zhou, Yuan-qian Li, Ning Su, Xiao-fang Pei, Li Yong. [Rapid analysis of genetically modified soybean by a duplex PCR-capillary electrophoresis system with laser-induced fluorescence detection].
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition.
2005 Jan; 36(1):119-23. doi:
". [PMID: 15702799] - Basel Qussi, Wolfgang G Suess. Investigation of the effect of various shellac coating compositions containing different water-soluble polymers on in vitro drug release.
Drug development and industrial pharmacy.
2005 Jan; 31(1):99-108. doi:
10.1081/ddc-44226. [PMID: 15704861] - Oluwatoyin A Odeku, John T Fell. Evaluation of khaya gum as a directly compressible matrix system for controlled release.
The Journal of pharmacy and pharmacology.
2004 Nov; 56(11):1365-70. doi:
10.1211/0022357044652. [PMID: 15525442] - Albert J Augustin, H Burkhard Dick. Oxidative tissue damage after phacoemulsification: influence of ophthalmic viscosurgical devices.
Journal of cataract and refractive surgery.
2004 Feb; 30(2):424-7. doi:
10.1016/s0886-3350(03)00577-7. [PMID: 15030835] - Xing Tang, XiaoLin Tian, Lei Ci. Preparation and evaluation of pH-dependent gradient-release pellets for TCM.
Drug development and industrial pharmacy.
2004; 30(10):1079-87. doi:
10.1081/ddc-200040286. [PMID: 15595574] - Y S R Krishnaiah, P Bhaskar, V Satyanarayana. Effect of carvone on the permeation of nimodipine from a membrane-moderated transdermal therapeutic system.
Die Pharmazie.
2003 Aug; 58(8):559-63. doi:
NULL. [PMID: 12967033] - Hong-tao Song, Tao Guo, Ru-hua Zhang, Yan Ma, Xian Li, Kai-shun Bi. [Studies on heart-protecting musk pH-dependent gradient-release pellets].
Yao xue xue bao = Acta pharmaceutica Sinica.
2002 Oct; 37(10):812-7. doi:
NULL. [PMID: 12567868] - Maichel N Roshdy, Roger L Schnaare, Edwin T Sugita, Joseph B Schwartz. The effect of controlled release tablet performance and hydrogel strength on in vitro/in vivo correlation.
Pharmaceutical development and technology.
2002 May; 7(2):155-68. doi:
10.1081/pdt-120003484. [PMID: 12066571] - K L Christensen, G P Pedersen, H G Kristensen. Physical stability of redispersible dry emulsions containing amorphous sucrose.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.
2002 Mar; 53(2):147-53. doi:
10.1016/s0939-6411(01)00232-6. [PMID: 11879996] - Mukesh C Gohel, Manhapra Sumitra G. Modulation of active pharmaceutical material release from a novel 'tablet in capsule system' containing an effervescent blend.
Journal of controlled release : official journal of the Controlled Release Society.
2002 Feb; 79(1-3):157-64. doi:
10.1016/s0168-3659(01)00541-7. [PMID: 11853927] - K Ito, S Kondo, M Kuzuya. A new drug delivery system using plasma-irradiated pharmaceutical aids. IX. Controlled-release of theophylline from double-compressed tablet composed of cellulose derivatives as wall material.
Chemical & pharmaceutical bulletin.
2001 Dec; 49(12):1615-20. doi:
10.1248/cpb.49.1615. [PMID: 11767083] - M K Kim, H Zhao, C H Lee, D D Kim. Formulation of a reservoir-type testosterone transdermal delivery system.
International journal of pharmaceutics.
2001 May; 219(1-2):51-9. doi:
10.1016/s0378-5173(01)00631-7. [PMID: 11337165] - C S Yong, J H Jung, J D Rhee, C K Kim, H G Choi. Physicochemical characterization and evaluation of buccal adhesive tablets containing omeprazole.
Drug development and industrial pharmacy.
2001 May; 27(5):447-55. doi:
10.1081/ddc-100104320. [PMID: 11448052] - J S Ding, X H Jiang, M Yuan. [Improving bioavailability of naftopidil by using bioadhesion in dogs].
Yao xue xue bao = Acta pharmaceutica Sinica.
2001 May; 36(5):377-80. doi:
NULL. [PMID: 12584863] - K L Christensen, G P Pedersen, H G Kristensen. Preparation of redispersible dry emulsions by spray drying.
International journal of pharmaceutics.
2001 Jan; 212(2):187-94. doi:
10.1016/s0378-5173(00)00596-2. [PMID: 11165076] - G Ikinci, Y Capan, S Senel, E Alaaddinoğlu, T Dalkara, A A Hincal. In vitro/in vivo studies on a buccal bioadhesive tablet formulation of carbamazepine.
Die Pharmazie.
2000 Oct; 55(10):762-5. doi:
NULL. [PMID: 11082839] - H Choi, J Jung, C S Yong, C Rhee, M Lee, J Han, K Park, C Kim. Formulation and in vivo evaluation of omeprazole buccal adhesive tablet.
Journal of controlled release : official journal of the Controlled Release Society.
2000 Sep; 68(3):405-12. doi:
10.1016/s0168-3659(00)00275-3. [PMID: 10974394] - S Miyazaki, N Kawasaki, T Nakamura, M Iwatsu, W M Hou, D Attwood. Oral mucosal bioadhesive tablets of pectin and HPMC: in vitro and in vivo evaluation.
International journal of pharmaceutics.
2000 Aug; 204(1-2):127-32. doi:
10.1016/s0378-5173(00)00491-9. [PMID: 11011995] - T Ishikawa, Y Watanabe, K Takayama, H Endo, M Matsumoto. Effect of hydroxypropylmethylcellulose (HPMC) on the release profiles and bioavailability of a poorly water-soluble drug from tablets prepared using macrogol and HPMC.
International journal of pharmaceutics.
2000 Jul; 202(1-2):173-8. doi:
10.1016/s0378-5173(00)00426-9. [PMID: 10915941] - K C Maki, M H Davidson, K C Malik, H H Albrecht, J O'Mullane, B P Daggy. Cholesterol lowering with high-viscosity hydroxypropylmethylcellulose.
The American journal of cardiology.
1999 Nov; 84(10):1198-203. doi:
10.1016/s0002-9149(99)00534-2. [PMID: 10569330] - A Mrhar, M Bogataj, I Grabnar, R Karba. Formulation of controlled release microspheres containing nicardipine: the role of pharmacokinetic modeling and computer simulation.
European journal of drug metabolism and pharmacokinetics.
1999 Jan; 24(1):55-61. doi:
10.1007/bf03190011. [PMID: 10412892] - J Ashby, P A Lefevre. The weanling male rat as an assay for endocrine disruption: preliminary observations.
Regulatory toxicology and pharmacology : RTP.
1997 Dec; 26(3):330-7. doi:
10.1006/rtph.1997.1177. [PMID: 9441923] - Z Vitková, K Gardavská, J Cizmarik. Study of local anaesthetics. Part 136. Influence of auxiliary substances on the release of pentacaine from drug forms.
Acta poloniae pharmaceutica.
1996 Jul; 53(4):253-8. doi:
". [PMID: 9415194] - H Yamakita, Y Matsukawa, T Maejima, T Osawa. Preparation of controlled release granules of TA-5707F using enteric polymers and ethylcellulose, and their in vivo evaluation.
Biological & pharmaceutical bulletin.
1996 Jan; 19(1):106-13. doi:
10.1248/bpb.19.106. [PMID: 8820921] - D Topping. Hydroxypropylmethylcellulose, viscosity, and plasma cholesterol control.
Nutrition reviews.
1994 May; 52(5):176-8. doi:
10.1111/j.1753-4887.1994.tb01416.x. [PMID: 8052459] - N R Cutler, S A Reines, L F McLean, J J Sramek, A G Porras, E L Hand. Pharmacokinetics and dose proportionality of D2-agonist MK-458 (HPMC) in parkinsonism.
Clinical pharmacokinetics.
1992 Mar; 22(3):223-30. doi:
10.2165/00003088-199222030-00004. [PMID: 1348452]