Toluidine Blue (BioDeep_00000652361)
代谢物信息卡片
toluidine blue for microscopy
化学式: C15H16ClN3S (305.0753406)
中文名称: 甲苯胺蓝O, 甲苯胺蓝
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC1=CC2=C(C=C1N)SC3=CC(=[N+](C)C)C=CC3=N2.[Cl-]
InChI: 1H
描述信息
D006401 - Hematologic Agents > D003029 - Coagulants > D006494 - Heparin Antagonists
D006401 - Hematologic Agents > D003029 - Coagulants > D006490 - Hemostatics
D004396 - Coloring Agents
同义名列表
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:87647
- PubChem: 7083
- ChEMBL: CHEMBL1790006
- ChEMBL: CHEMBL562639
- MeSH: Tolonium Chloride
- CAS: 6586-04-5
- CAS: 92-31-9
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Karina Borba Paulino Dos Santos, Ana Flavia Gatto Raimundo, Eduardo Makiyama Klosowski, Byanca Thais Lima de Souza, Márcio Shigueaki Mito, Renato Polimeni Constantin, Gislaine Cristiane Mantovanelli, Juliana Morais Mewes, Paulo Francisco Veiga Bizerra, Paulo Vinicius Moreira da Costa Menezes, Karina Sayuri Utsunomiya, Eduardo Hideo Gilglioni, Rogério Marchiosi, Wanderley Dantas Dos Santos, Osvaldo Ferrarese-Filho, Wilker Caetano, Paulo Cesar de Souza Pereira, Renato Sonchini Gonçalves, Jorgete Constantin, Emy Luiza Ishii-Iwamoto, Rodrigo Polimeni Constantin. Toluidine blue O directly and photodynamically impairs the bioenergetics of liver mitochondria: a potential mechanism of hepatotoxicity.
Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
2023 Feb; 22(2):279-302. doi:
10.1007/s43630-022-00312-1. [PMID: 36152272] - Qi He, Junzheng Yang, Zhaofeng Pan, Gangyu Zhang, Baihao Chen, Shaocong Li, Jiacong Xiao, Fengjin Tan, Zihao Wang, Peng Chen, Haibin Wang. Biochanin A protects against iron overload associated knee osteoarthritis via regulating iron levels and NRF2/System xc-/GPX4 axis.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
2023 Jan; 157(?):113915. doi:
10.1016/j.biopha.2022.113915. [PMID: 36379122] - Wenbing Zhi, Shengnan Jiang, Zongren Xu, Yuye An, Jing Chen, Ye Li, Yang Liu, Hong Zhang. Oxysophocarpine inhibits airway inflammation and mucus hypersecretion through JNK/AP-1 pathway in vivo and in vitro.
Fitoterapia.
2022 Oct; 162(?):105278. doi:
10.1016/j.fitote.2022.105278. [PMID: 35970410] - Jia-Zi Dong, Pei-Jing Rong, Tie-Ming Ma, Dan Wang, Xiao-Tong Wang, Ye Qiao. [Influence of electroacupuncture of"Zusanli"(ST36)on mast cells/TRPV1 signaling pathway in visceral hypersensitivity rats with functional dyspepsia].
Zhen ci yan jiu = Acupuncture research.
2022 Jul; 47(7):592-7. doi:
10.13702/j.1000-0607.20210937. [PMID: 35880275] - Pengcheng Zhou, Wei Yu, Chuantao Zhang, Keling Chen, Wenjun Tang, Xuelian Li, Zijun Liu, Qianming Xia. Tiao-bu-fei-shen formula promotes downregulation of the caveolin 1-p38 mapk signaling pathway in COPD - Associated tracheobronchomalacia cell model.
Journal of ethnopharmacology.
2022 Jul; 293(?):115256. doi:
10.1016/j.jep.2022.115256. [PMID: 35367574] - Felipe Andrade-Villalobos, Daniel Zúñiga-Núñez, Denis Fuentealba, Angelica Fierro. Binding of toluidine blue-myristic acid derivative to cucurbit[7]uril and human serum albumin: computational and biophysical insights towards a biosupramolecular assembly.
Physical chemistry chemical physics : PCCP.
2022 Feb; 24(5):3222-3230. doi:
10.1039/d1cp04307b. [PMID: 35044390] - Sanam Sardaremelli, Mohammad Hasanzadeh, Farzad Seidi. Enzymatic recognition of hydrogen peroxide (H2 O2 ) in human plasma samples using HRP immobilized on the surface of poly(arginine-toluidine blue)- Fe3 O4 nanoparticles modified polydopamine; A novel biosensor.
Journal of molecular recognition : JMR.
2021 11; 34(11):e2928. doi:
10.1002/jmr.2928. [PMID: 34378255] - José Robinson-Duggon, Christopher D McTiernan, Marcelo Muñoz, Daniel Guerra, Elizabeth Escobar Álvarez, Felipe Andrade-Villalobos, Angélica Fierro, Ana María Edwards, Emilio I Alarcon, Denis Fuentealba. Biosupramolecular complexes of amphiphilic photosensitizers with human serum albumin and cucurbit[7]uril as carriers for photodynamic therapy.
Journal of photochemistry and photobiology. B, Biology.
2021 Oct; 223(?):112284. doi:
10.1016/j.jphotobiol.2021.112284. [PMID: 34450362] - Parinaz Abdollahiyan, Arezoo Mohammadzadeh, Mohammad Hasanzadeh. Chemical binding of molecular-imprinted polymer to biotinilated antibody: Utilization of molecular imprinting polymer as intelligent synthetic biomaterials toward recognition of carcinoma embryonic antigen in human plasma sample.
Journal of molecular recognition : JMR.
2021 09; 34(9):e2897. doi:
10.1002/jmr.2897. [PMID: 33759263] - Lucas G Moreira, Alexandre M Almeida, Tyler Nield, Sabrina A Camacho, Pedro H B Aoki. Modulating photochemical reactions in Langmuir monolayers of Escherichia coli lipid extract with the binding mechanisms of eosin decyl ester and toluidine blue-O photosensitizers.
Journal of photochemistry and photobiology. B, Biology.
2021 May; 218(?):112173. doi:
10.1016/j.jphotobiol.2021.112173. [PMID: 33799010] - Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome.
Cell reports.
2021 04; 35(4):109040. doi:
10.1016/j.celrep.2021.109040. [PMID: 33910017] - Valdir Carvalho Ribeiro, Carlos André Espolador Leitão. Utilisation of Toluidine blue O pH 4.0 and histochemical inferences in plant sections obtained by free-hand.
Protoplasma.
2020 May; 257(3):993-1008. doi:
10.1007/s00709-019-01473-0. [PMID: 31865451] - Sanam Sardaremelli, Habib Razmi, Mohamad Hasanzadeh, Nasrin Shadjou. A novel bioassay for the monitoring of hydrogen peroxide in human plasma samples based on binding of horseradish peroxidase-conjugated prostate specific antigen to poly (toluidine blue) as imprinted polymer receptor.
International journal of biological macromolecules.
2020 Feb; 145(?):311-324. doi:
10.1016/j.ijbiomac.2019.12.195. [PMID: 31881306] - Alexandre M Almeida, Osvaldo N Oliveira, Pedro H B Aoki. Role of Toluidine Blue-O Binding Mechanism for Photooxidation in Bioinspired Bacterial Membranes.
Langmuir : the ACS journal of surfaces and colloids.
2019 12; 35(51):16745-16751. doi:
10.1021/acs.langmuir.9b03045. [PMID: 31746210] - Tobie D Lee, Olivia W Lee, Kyle R Brimacombe, Lu Chen, Rajarshi Guha, Sabrina Lusvarghi, Bethilehem G Tebase, Carleen Klumpp-Thomas, Robert W Robey, Suresh V Ambudkar, Min Shen, Michael M Gottesman, Matthew D Hall. A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein.
Molecular pharmacology.
2019 11; 96(5):629-640. doi:
10.1124/mol.119.115964. [PMID: 31515284] - Anju V T, Parasuraman Paramanantham, Sruthil Lal S B, Alok Sharan, Asad Syed, Needa A Bahkali, Marzouq H Alsaedi, Kaviyarasu K, Siddhardha Busi. Antimicrobial photodynamic activity of toluidine blue-carbon nanotube conjugate against Pseudomonas aeruginosa and Staphylococcus aureus - Understanding the mechanism of action.
Photodiagnosis and photodynamic therapy.
2019 Sep; 27(?):305-316. doi:
10.1016/j.pdpdt.2019.06.014. [PMID: 31228562] - F T Liu, W Shang, W Li, S B Wan, J Cui. [Experimental study of toluidine blue-dextran-40 as lymphatic tracer in head and neck region].
Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology.
2019 Jul; 54(7):481-486. doi:
10.3760/cma.j.issn.1002-0098.2019.07.009. [PMID: 31288329] - Sheetal K Bhardwaj, Ruchika Chauhan, Premlata Yadav, Subhasis Ghosh, Ajit K Mahapatro, Jay Singh, Tinku Basu. Bi-enzyme functionalized electro-chemically reduced transparent graphene oxide platform for triglyceride detection.
Biomaterials science.
2019 Mar; 7(4):1598-1606. doi:
10.1039/c8bm01406j. [PMID: 30698597] - Priyal Chikhaliwala, Rakesh Rai, Sudeshna Chandra. Simultaneous voltammetric immunodetection of alpha-fetoprotein and glypican-3 using a glassy carbon electrode modified with magnetite-conjugated dendrimers.
Mikrochimica acta.
2019 03; 186(4):255. doi:
10.1007/s00604-019-3354-4. [PMID: 30904972] - Benedicto de Campos Vidal, Maria Luiza S Mello. Toluidine blue staining for cell and tissue biology applications.
Acta histochemica.
2019 Feb; 121(2):101-112. doi:
10.1016/j.acthis.2018.11.005. [PMID: 30463688] - Peng Liu, Boyan Tian, Lifei Yang, Xinglong Zheng, Xufeng Zhang, Jianhui Li, Xuemin Liu, Yi Lv, Junxi Xiang. Hemocompatibility improvement of decellularized spleen matrix for constructing transplantable bioartificial liver.
Biomedical materials (Bristol, England).
2019 01; 14(2):025003. doi:
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Histochemistry and cell biology.
2019 Jan; 151(1):75-83. doi:
10.1007/s00418-018-1714-5. [PMID: 30140953] - Sylvain Loubéry, Julien De Giorgi, Anne Utz-Pugin, Lara Demonsais, Luis Lopez-Molina. A Maternally Deposited Endosperm Cuticle Contributes to the Physiological Defects of transparent testa Seeds.
Plant physiology.
2018 07; 177(3):1218-1233. doi:
10.1104/pp.18.00416. [PMID: 29848749] - J A Ribeiro, C M Pereira, A F Silva, M Goreti F Sales. Disposable electrochemical detection of breast cancer tumour marker CA 15-3 using poly(Toluidine Blue) as imprinted polymer receptor.
Biosensors & bioelectronics.
2018 Jun; 109(?):246-254. doi:
10.1016/j.bios.2018.03.011. [PMID: 29571161] - Weiqi Zhang, Ching-Hsuan Tung. Real-Time Visualization of Lysosome Destruction Using a Photosensitive Toluidine Blue Nanogel.
Chemistry (Weinheim an der Bergstrasse, Germany).
2018 Feb; 24(9):2089-2093. doi:
10.1002/chem.201705697. [PMID: 29314346] - Viviana Teresa Orlandi, Fabrizio Bolognese, Eleonora Martegani, Vincenzo Cantaluppi, Claudio Medana, Paola Barbieri. Response to photo-oxidative stress of Pseudomonas aeruginosa PAO1 mutants impaired in different functions.
Microbiology (Reading, England).
2017 Nov; 163(11):1557-1567. doi:
10.1099/mic.0.000543. [PMID: 29022867] - Kevser Biberoglu, Melike Yuksel Tek, Seyhan Turk Ghasemi, Ozden Tacal. Toluidine blue O is a potent inhibitor of human cholinesterases.
Archives of biochemistry and biophysics.
2016 08; 604(?):57-62. doi:
10.1016/j.abb.2016.06.005. [PMID: 27296777] - María Teresa Sánchez-Fito, Elisa Oltra. Optimized Treatment of Heparinized Blood Fractions to Make Them Suitable for Analysis.
Biopreservation and biobanking.
2015 Aug; 13(4):287-95. doi:
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BMC oral health.
2014 Nov; 14(?):132. doi:
10.1186/1472-6831-14-132. [PMID: 25366394] - Ulrich Schiffner, Georg Cachovan, Jochen Bastian, Anton Sculean, Sigrun Eick. In vitro activity of photoactivated disinfection using a diode laser in infected root canals.
Acta odontologica Scandinavica.
2014 Nov; 72(8):673-80. doi:
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Transgenic research.
2014 Oct; 23(5):817-26. doi:
10.1007/s11248-014-9808-x. [PMID: 24929937] - Wenzhi Cao, Yun Liu, Guoliang Jiang, Ting Wu. [A comparison of methods for identifying mast cells of Cyprinus carpio].
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology.
2014 Aug; 30(8):872-4, 877. doi:
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2014 Feb; 243(2):257-78. doi:
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Materials science & engineering. C, Materials for biological applications.
2013 Jul; 33(5):2639-47. doi:
10.1016/j.msec.2013.02.022. [PMID: 23623079] - Sigrun Eick, Giedre Markauskaite, Sandor Nietzsche, Oliver Laugisch, Giovanni E Salvi, Anton Sculean. Effect of photoactivated disinfection with a light-emitting diode on bacterial species and biofilms associated with periodontitis and peri-implantitis.
Photodiagnosis and photodynamic therapy.
2013 May; 10(2):156-67. doi:
10.1016/j.pdpdt.2012.12.001. [PMID: 23769282] - Shiguang Huang, Fangli Lu, Ying Chen, Bo Huang, Man Liu. Mast cell degranulation in human periodontitis.
Journal of periodontology.
2013 Feb; 84(2):248-55. doi:
10.1902/jop.2012.120066. [PMID: 22509749] - Qian Xing, Audrey Creff, Andrew Waters, Hirokazu Tanaka, Justin Goodrich, Gwyneth C Ingram. ZHOUPI controls embryonic cuticle formation via a signalling pathway involving the subtilisin protease ABNORMAL LEAF-SHAPE1 and the receptor kinases GASSHO1 and GASSHO2.
Development (Cambridge, England).
2013 Feb; 140(4):770-9. doi:
10.1242/dev.088898. [PMID: 23318634] - Philip Hands, Sofia Kourmpetli, Donna Sharples, Robert G Harris, Sinéad Drea. Analysis of grain characters in temperate grasses reveals distinctive patterns of endosperm organization associated with grain shape.
Journal of experimental botany.
2012 Oct; 63(17):6253-66. doi:
10.1093/jxb/ers281. [PMID: 23081982] - Frank Petrat, Matthias Hartmann, Ernst Schmidt, Florian Grabellus, Tim Hamburger, Herbert de Groot. Toluidine blue for the intraoperative staining of the ureters. Studies on the safe administration in rats.
Langenbeck's archives of surgery.
2012 Aug; 397(6):983-93. doi:
10.1007/s00423-012-0907-y. [PMID: 22297624] - Ferruh Artunc, Michael Sayer, Volker Steger. [Progredient dyspnea and poor drainage in a peritoneal dialysis patient - case 2/2012].
Deutsche medizinische Wochenschrift (1946).
2012 Feb; 137(7):314. doi:
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Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology.
2012 Jan; 41(1):96-105. doi:
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Archives of oral biology.
2011 Jul; 56(7):672-7. doi:
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Journal of lipid research.
2011 Jun; 52(6):1128-1138. doi:
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The Journal of pharmacology and experimental therapeutics.
2011 May; 337(2):411-22. doi:
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Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics.
2010 Dec; 110(6):713-9. doi:
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Oral oncology.
2010 Jun; 46(6):418-22. doi:
10.1016/j.oraloncology.2010.03.006. [PMID: 20371204] - Angela M Verdoni, Sakae Ikeda, Akihiro Ikeda. Serum response factor is essential for the proper development of skin epithelium.
Mammalian genome : official journal of the International Mammalian Genome Society.
2010 Feb; 21(1-2):64-76. doi:
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Fertility and sterility.
2009 Apr; 91(4):1110-8. doi:
10.1016/j.fertnstert.2008.01.047. [PMID: 18462729] - Z Cai, P C Blumbergs, J W Finnie, J Manavis, P D Thompson. Selective vulnerability of peripheral nerves in avian riboflavin deficiency demyelinating polyneuropathy.
Veterinary pathology.
2009 Jan; 46(1):88-96. doi:
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Journal of experimental botany.
2009; 60(3):979-91. doi:
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The International journal of periodontics & restorative dentistry.
2008 Dec; 28(6):551-7. doi:
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Current microbiology.
2008 Oct; 57(4):269-73. doi:
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Veterinary immunology and immunopathology.
2008 Jul; 124(1-2):19-28. doi:
10.1016/j.vetimm.2008.01.005. [PMID: 18342956] - Jamil Awad Shibli, Marilia Compagnoni Martins, Fernando Salimon Ribeiro, Valdir Gouveia Garcia, Francisco Humberto Nociti, Elcio Marcantonio. Lethal photosensitization and guided bone regeneration in treatment of peri-implantitis: an experimental study in dogs.
Clinical oral implants research.
2006 Jun; 17(3):273-81. doi:
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Journal of biotechnology.
2006 May; 123(3):356-66. doi:
10.1016/j.jbiotec.2005.11.023. [PMID: 16522340] - Liang-qia Guo, Fang-gui Ye, Xu-cong Lin, Zeng-hong Xie. [Determination of nucleic acids using toluidine blue as a fluorescence probe].
Guang pu xue yu guang pu fen xi = Guang pu.
2006 Jan; 26(1):121-4. doi:
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Histopathology.
2005 Nov; 47(5):534-5. doi:
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Biology of reproduction.
2005 Feb; 72(2):346-57. doi:
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The Journal of pharmacology and experimental therapeutics.
2005 Feb; 312(2):482-91. doi:
10.1124/jpet.104.075101. [PMID: 15475591] - Wendy W Barclay, Ralph D Woodruff, M Craig Hall, Scott D Cramer. A system for studying epithelial-stromal interactions reveals distinct inductive abilities of stromal cells from benign prostatic hyperplasia and prostate cancer.
Endocrinology.
2005 Jan; 146(1):13-8. doi:
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Pediatric nephrology (Berlin, Germany).
2004 Feb; 19(2):157-63. doi:
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The Plant journal : for cell and molecular biology.
2004 Jan; 37(1):139-46. doi:
10.1046/j.1365-313x.2003.01946.x. [PMID: 14675439] - Francesca Maccari, Nicola Volpi. Detection of submicrogram quantities of Escherichia coli lipopolysaccharides by agarose-gel electrophoresis.
Analytical biochemistry.
2003 Nov; 322(2):185-9. doi:
10.1016/j.ab.2003.08.017. [PMID: 14596826] - Donco Matevski, Robert Weersink, Howard C Tenenbaum, Brian Wilson, Richard P Ellen, Guylaine Lépine. Lethal photosensitization of periodontal pathogens by a red-filtered Xenon lamp in vitro.
Journal of periodontal research.
2003 Aug; 38(4):428-35. doi:
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Journal of periodontology.
2003 Mar; 74(3):338-45. doi:
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