4-Nitroquinoline (BioDeep_00000648676)
代谢物信息卡片
4-Nitroquinoline
化学式: C9H6N2O2 (174.04292560000002)
中文名称: 4-硝基喹啉
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CC=C2C(=C1)C(=CC=N2)[N+](=O)[O-]
InChI: InChI=1S/C9H6N2O2/c12-11(13)9-5-6-10-8-4-2-1-3-7(8)9/h1-6H
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Aoife L McCarthy, Yvonne C O'Callaghan, Alan Connolly, Charles O Piggott, Richard J Fitzgerald, Nora M O'Brien. Phenolic extracts of brewers' spent grain (BSG) as functional ingredients - assessment of their DNA protective effect against oxidant-induced DNA single strand breaks in U937 cells.
Food chemistry.
2012 Sep; 134(2):641-6. doi:
10.1016/j.foodchem.2012.02.133. [PMID: 23107673] - Yu-Ching Liu, Heng-Chien Ho, Miau-Rong Lee, Kuang-Chi Lai, Chung-Min Yeh, Yueh-Min Lin, Tin-Yun Ho, Chien-Yun Hsiang, Jing-Gung Chung. Early induction of cytokines/cytokine receptors and Cox2, and activation of NF-κB in 4-nitroquinoline 1-oxide-induced murine oral cancer model.
Toxicology and applied pharmacology.
2012 Jul; 262(2):107-16. doi:
10.1016/j.taap.2012.04.023. [PMID: 22561872] - Ashok Kumar Pandurangan, Srinivasan Periasamy, Suresh Kumar Anandasadagopan, Sudhandiran Ganapasam, Shyamala Devi Chennam Srinivasalu. Green tea polyphenol protection against 4-nitroquinoline 1-oxide-induced bone marrow lipid peroxidation and genotoxicity in Wistar rats.
Asian Pacific journal of cancer prevention : APJCP.
2012; 13(8):4107-12. doi:
10.7314/apjcp.2012.13.8.4107. [PMID: 23098525] - Miroslava Macova, Simon Toze, Leonie Hodgers, Jochen F Mueller, Michael Bartkow, Beate I Escher. Bioanalytical tools for the evaluation of organic micropollutants during sewage treatment, water recycling and drinking water generation.
Water research.
2011 Aug; 45(14):4238-47. doi:
10.1016/j.watres.2011.05.032. [PMID: 21704353] - Radava R Korać, Kapil M Khambholja. Potential of herbs in skin protection from ultraviolet radiation.
Pharmacognosy reviews.
2011 Jul; 5(10):164-73. doi:
10.4103/0973-7847.91114. [PMID: 22279374] - Nai Wen Chang, Ming-Hsui Tsai, Chingju Lin, Hui Ting Hsu, Pei-Yi Chu, Chung-Min Yeh, Chang-Fang Chiu, Kun-Tu Yeh. Fenofibrate exhibits a high potential to suppress the formation of squamous cell carcinoma in an oral-specific 4-nitroquinoline 1-oxide/arecoline mouse model.
Biochimica et biophysica acta.
2011 Apr; 1812(4):558-64. doi:
10.1016/j.bbadis.2010.11.002. [PMID: 21081159] - Takuji Tanaka, Masashi Hosokawa, Yumiko Yasui, Rikako Ishigamori, Kazuo Miyashita. Cancer chemopreventive ability of conjugated linolenic acids.
International journal of molecular sciences.
2011; 12(11):7495-509. doi:
10.3390/ijms12117495. [PMID: 22174613] - Jose L Perez, Guddarangavvanahally K Jayaprakasha, Adriana Cadena, Elvia Martinez, Hassan Ahmad, Bhimanagouda S Patil. In vivo induction of phase II detoxifying enzymes, glutathione transferase and quinone reductase by citrus triterpenoids.
BMC complementary and alternative medicine.
2010 Sep; 10(?):51. doi:
10.1186/1472-6882-10-51. [PMID: 20846448] - Chih-Ho Lai, Nai-Wen Chang, Chin-Fen Lin, Chia-Der Lin, Ying-Ju Lin, Lei Wan, Jim Jinn-Chyuan Sheu, Shih-Yin Chen, Yi-Ping Huang, Yu-Ting Sing, Tse-Wen Tao, Cheng-Kuo Lai, Ming-Hsui Tsai, Hong-Lin Chan, Yu-Jen Jou, Cheng-Wen Lin. Proteomics-based identification of haptoglobin as a novel plasma biomarker in oral squamous cell carcinoma.
Clinica chimica acta; international journal of clinical chemistry.
2010 Jul; 411(13-14):984-91. doi:
10.1016/j.cca.2010.03.028. [PMID: 20359475] - Natsuko Suwaki, Emma S Child, Lucy M Elphick, David J Mann. Dose-dependent changes in cyclin D1 in response to 4-nitroquinoline 1-oxide-induced DNA damage.
Archives of biochemistry and biophysics.
2010 May; 497(1-2):55-61. doi:
10.1016/j.abb.2010.03.003. [PMID: 20214871] - Periasamy Srinivasan, Subramaniyan Suchalatha, Pon Velayutham Anandh Babu, Rethinam Sundaresan Devi, Shoba Narayan, Kuruvimalai Ekambaram Sabitha, Chennam Srinivasulu Shyamala Devi. Chemopreventive and therapeutic modulation of green tea polyphenols on drug metabolizing enzymes in 4-Nitroquinoline 1-oxide induced oral cancer.
Chemico-biological interactions.
2008 Apr; 172(3):224-34. doi:
10.1016/j.cbi.2008.01.010. [PMID: 18336807] - Hidekatsu Yanai, Yoshiharu Tomono, Kumie Ito, Nobuyuki Furutani, Hiroshi Yoshida, Norio Tada. Diacylglycerol oil for the metabolic syndrome.
Nutrition journal.
2007 Dec; 6(?):43. doi:
10.1186/1475-2891-6-43. [PMID: 18072966] - Canhua Jiang, Dongxia Ye, Weiliu Qiu, Xiuli Zhang, Zhiyuan Zhang, Di He, Ping Zhang, Wantao Chen. Response of lymphocyte subsets and cytokines to Shenyang prescription in Sprague-Dawley rats with tongue squamous cell carcinomas induced by 4NQO.
BMC cancer.
2007 Mar; 7(?):40. doi:
10.1186/1471-2407-7-40. [PMID: 17338814] - Periasamy Srinivasan, Kuruvimalai Ekambaram Sabitha, Chennam Srinivasulu Shyamaladevi. Attenuation of 4-nitroquinoline 1-oxide induced in vitro lipid peroxidation by green tea polyphenols.
Life sciences.
2007 Feb; 80(12):1080-6. doi:
10.1016/j.lfs.2006.11.051. [PMID: 17280688] - Yongdoo Choi, Sang Yoon Kim, Kyeongsoon Park, Jehoon Yang, Kyung-Ja Cho, Hyun Ja Kwon, Youngro Byun. Chemopreventive efficacy of all-trans-retinoic acid in biodegradable microspheres against epithelial cancers: results in a 4-nitroquinoline 1-oxide-induced oral carcinogenesis model.
International journal of pharmaceutics.
2006 Aug; 320(1-2):45-52. doi:
10.1016/j.ijpharm.2006.04.003. [PMID: 16730144] - Periasamy Srinivasan, Kuruvimalai Ekambaram Sabitha, Chennam Srinivasulu Shyamaladevi. Modulatory efficacy of green tea polyphenols on glycoconjugates and immunological markers in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis-A therapeutic approach.
Chemico-biological interactions.
2006 Aug; 162(2):149-56. doi:
10.1016/j.cbi.2006.05.021. [PMID: 16859662] - Ilhan Akan, Selma Akan, Hakan Akca, Burhan Savas, Tomris Ozben. Multidrug resistance-associated protein 1 (MRP1) mediated vincristine resistance: effects of N-acetylcysteine and Buthionine sulfoximine.
Cancer cell international.
2005 Jul; 5(1):22. doi:
10.1186/1475-2867-5-22. [PMID: 16042792] - Periasamy Srinivasan, Kuruvimalai Ekambaram Sabitha, Chennam Srinivasulu Shyamaladevi. Therapeutic efficacy of green tea polyphenols on cellular thiols in 4-Nitroquinoline 1-oxide-induced oral carcinogenesis.
Chemico-biological interactions.
2004 Oct; 149(2-3):81-7. doi:
10.1016/j.cbi.2004.06.006. [PMID: 15501430] - Kazuhiko Yamamoto, Wakashi Kitayama, Ayumi Denda, Ayumu Morisaki, Hiroki Kuniyasu, Tadaaki Kirita. Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide.
Cancer letters.
2003 Sep; 199(2):121-9. doi:
10.1016/s0304-3835(03)00382-3. [PMID: 12969784] - S Balasenthil, C R Ramachandran, S Nagini. Prevention of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis by garlic.
Fitoterapia.
2001 Jun; 72(5):524-31. doi:
10.1016/s0367-326x(01)00262-3. [PMID: 11429247] - . .
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