1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine (BioDeep_00000648078)

   


代谢物信息卡片


2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine

化学式: C11H16INO2 (321.0225746)
中文名称: 4-碘-2,5-二甲氧基-α-甲基苯甲胺
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CC(CC1=CC(=C(C=C1OC)I)OC)N
InChI: InChI=1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3

描述信息

D018377 - Neurotransmitter Agents > D018490 - Serotonin Agents > D017366 - Serotonin Receptor Agonists
D002491 - Central Nervous System Agents > D011619 - Psychotropic Drugs > D006213 - Hallucinogens

同义名列表

2 个代谢物同义名

2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine; 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine



数据库引用编号

5 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

0 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。



文献列表

  • Eun-Joo Shin, Ji Hoon Jeong, Bao-Trong Nguyen, Naveen Sharma, Seung-Yeol Nah, Yoon Hee Chung, Yi Lee, Jae Kyung Byun, Toshitaka Nabeshima, Sung Kwon Ko, Hyoung-Chun Kim. Ginsenoside Re Protects against Serotonergic Behaviors Evoked by 2,5-Dimethoxy-4-iodo-amphetamine in Mice via Inhibition of PKCδ-Mediated Mitochondrial Dysfunction. International journal of molecular sciences. 2021 Jul; 22(13):. doi: 10.3390/ijms22137219. [PMID: 34281274]
  • Jian Shuai, Yufang Gao, Ling Chen, Zhongli Wang. Role of serotonin in regulation of pancreatic and mesenteric arterial function in diabetic mice. European journal of pharmacology. 2021 Jun; 901(?):174070. doi: 10.1016/j.ejphar.2021.174070. [PMID: 33798598]
  • Mark J Henderson, Kathleen A Trychta, Shyh-Ming Yang, Susanne Bäck, Adam Yasgar, Emily S Wires, Carina Danchik, Xiaokang Yan, Hideaki Yano, Lei Shi, Kuo-Jen Wu, Amy Q Wang, Dingyin Tao, Gergely Zahoránszky-Kőhalmi, Xin Hu, Xin Xu, David Maloney, Alexey V Zakharov, Ganesha Rai, Fumihiko Urano, Mikko Airavaara, Oksana Gavrilova, Ajit Jadhav, Yun Wang, Anton Simeonov, Brandon K Harvey. A target-agnostic screen identifies approved drugs to stabilize the endoplasmic reticulum-resident proteome. Cell reports. 2021 04; 35(4):109040. doi: 10.1016/j.celrep.2021.109040. [PMID: 33910017]
  • Long Hongyan, Zhang Mengjiao, Wang Chunyan, Huang Yaruo. Rhynchophylline Attenuates Neurotoxicity in Tourette Syndrome Rats. Neurotoxicity research. 2019 Nov; 36(4):679-687. doi: 10.1007/s12640-019-00059-1. [PMID: 31115771]
  • Long Hongyan, Zhang Mengjiao, Wang Chunyan, Huang Yaruo. Rhynchophyllin attenuates neuroinflammation in Tourette syndrome rats via JAK2/STAT3 and NF-κB pathways. Environmental toxicology. 2019 Oct; 34(10):1114-1120. doi: 10.1002/tox.22813. [PMID: 31231976]
  • Hongyan Long, Chunyan Wang, Jie Ruan, Mengjiao Zhang, Yaruo Huang. Gastrodin attenuates neuroinflammation in DOI-induce Tourette syndrome in rats. Journal of biochemical and molecular toxicology. 2019 May; 33(5):e22302. doi: 10.1002/jbt.22302. [PMID: 30790395]
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  • Simona Bertoni, Paola Ghizzardi, Fiore Cattaruzza, Vigilio Ballabeni, Mariannina Impicciatore, Massimiliano Tognolini, Costanza A M Lagrasta, Elisabetta Barocelli. Evidence for the involvement of 5-HT2A receptors in mild mesenteric ischemia/reperfusion dysfunctions in mice. Pharmacological research. 2007 Dec; 56(6):550-5. doi: 10.1016/j.phrs.2007.10.004. [PMID: 18024056]
  • Jian Qiu, Changhui Xue, Martha A Bosch, Jonathan G Murphy, Wei Fan, Oline K Rønnekleiv, Martin J Kelly. Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons: role in energy homeostasis in females. Molecular pharmacology. 2007 Oct; 72(4):885-96. doi: 10.1124/mol.107.038083. [PMID: 17622577]
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  • Brigitte Sonier, Madeleine Arseneault, Carole Lavigne, Rodney J Ouellette, Cathy Vaillancourt. The 5-HT2A serotoninergic receptor is expressed in the MCF-7 human breast cancer cell line and reveals a mitogenic effect of serotonin. Biochemical and biophysical research communications. 2006 May; 343(4):1053-9. doi: 10.1016/j.bbrc.2006.03.080. [PMID: 16580628]
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  • Michelle Landry, Mark Frasier, Zhuo Chen, Louis D Van De Kar, Yahong Zhang, Francisca Garcia, George Battaglia. Fluoxetine treatment of prepubescent rats produces a selective functional reduction in the 5-HT2A receptor-mediated stimulation of oxytocin. Synapse (New York, N.Y.). 2005 Nov; 58(2):102-9. doi: 10.1002/syn.20187. [PMID: 16088947]
  • Ying Qu, Nelly Villacreses, Dennis L Murphy, Stanley I Rapoport. 5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter. Psychopharmacology. 2005 Jun; 180(1):12-20. doi: 10.1007/s00213-005-2231-5. [PMID: 15834538]
  • Mireille Basselin, Lisa Chang, Ruth Seemann, Jane M Bell, Stanley I Rapoport. Chronic lithium administration to rats selectively modifies 5-HT2A/2C receptor-mediated brain signaling via arachidonic acid. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2005 Mar; 30(3):461-72. doi: 10.1038/sj.npp.1300611. [PMID: 15562295]
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