pyrimidone (BioDeep_00000645944)
代谢物信息卡片
化学式: C4H4N2O (96.0324)
中文名称: 2-羟基嘧啶
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1=CNC(=O)N=C1
InChI: InChI=1S/C4H4N2O/c7-4-5-2-1-3-6-4/h1-3H,(H,5,6,7)
数据库引用编号
6 个数据库交叉引用编号
- ChEBI: CHEBI:53577
- PubChem: 68401
- ChEMBL: CHEMBL1650607
- CAS: 55949-38-7
- CAS: 51953-13-0
- CAS: 557-01-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Andreas Kretschmann, Roman Ashauer, Thomas G Preuss, Piet Spaak, Beate I Escher, Juliane Hollender. Toxicokinetic model describing bioconcentration and biotransformation of diazinon in Daphnia magna.
Environmental science & technology.
2011 Jun; 45(11):4995-5002. doi:
10.1021/es104324v. [PMID: 21561125] - Libin Xu, Zeljka Korade, Jr Dale A Rosado, Wei Liu, Connor R Lamberson, Ned A Porter. An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome.
Journal of lipid research.
2011 Jun; 52(6):1222-1233. doi:
10.1194/jlr.m014498. [PMID: 21402677] - Nair Sreejayan, Xiaoping Yang, Kamalakannan Palanichamy, Kurt Dolence, Jun Ren. Antioxidant properties of argpyrimidine.
European journal of pharmacology.
2008 Sep; 593(1-3):30-5. doi:
10.1016/j.ejphar.2008.07.030. [PMID: 18692042] - F Christoph, C Kempkensteffen, S Weikert, J Köllermann, H Krause, K Miller, M Schostak, M Schrader. Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer.
British journal of cancer.
2006 Dec; 95(12):1701-7. doi:
10.1038/sj.bjc.6603482. [PMID: 17133271] - Jan H Beumer, Erin Joseph, Merrill J Egorin, Robert S Parker, David Z D'argenio, Joseph M Covey, Julie L Eiseman. A mass balance and disposition study of the DNA methyltransferase inhibitor zebularine (NSC 309132) and three of its metabolites in mice.
Clinical cancer research : an official journal of the American Association for Cancer Research.
2006 Oct; 12(19):5826-33. doi:
10.1158/1078-0432.ccr-06-1234. [PMID: 17020990] - Hervé Geneste, Wilhelm Amberg, Gisela Backfisch, Armin Beyerbach, Wilfried M Braje, Jürgen Delzer, Andreas Haupt, Charles W Hutchins, Linda L King, Daryl R Sauer, Liliane Unger, Wolfgang Wernet. Synthesis and SAR of highly potent and selective dopamine D3-receptor antagonists: variations on the 1H-pyrimidin-2-one theme.
Bioorganic & medicinal chemistry letters.
2006 Apr; 16(7):1934-7. doi:
10.1016/j.bmcl.2005.12.079. [PMID: 16439127] - Karen A O'Leary, Robert J Edwards, Margaret M Town, Alan R Boobis. Genetic and other sources of variation in the activity of serum paraoxonase/diazoxonase in humans: consequences for risk from exposure to diazinon.
Pharmacogenetics and genomics.
2005 Jan; 15(1):51-60. doi:
10.1097/01213011-200501000-00008. [PMID: 15864126] - K Takekawa, K Sugihara, S Kitamura, S Ohta. Enzymatic and non-enzymatic reduction of brucine N-oxide by aldehyde oxidase and catalase.
Xenobiotica; the fate of foreign compounds in biological systems.
2001 Nov; 31(11):769-82. doi:
10.1080/00498250110065612. [PMID: 11765140]
