Nilestriol (BioDeep_00000645848)
代谢物信息卡片
Nilestriol
化学式: C25H32O3 (380.2351)
中文名称: 烯丙三醇
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC12CCC3C(C1CC(C2(C#C)O)O)CCC4=C3C=CC(=C4)OC5CCCC5
InChI: InChI=1S/C25H32O3/c1-3-25(27)23(26)15-22-21-10-8-16-14-18(28-17-6-4-5-7-17)9-11-19(16)20(21)12-13-24(22,25)2/h1,9,11,14,17,20-23,26-27H,4-8,10,12-13,15H2,2H3/t20-,21-,22+,23-,24+,25+/m1/s1
描述信息
D006730 - Hormones, Hormone Substitutes, and Hormone Antagonists > D006728 - Hormones > D004967 - Estrogens
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C1636 - Therapeutic Steroid Hormone
C147908 - Hormone Therapy Agent > C548 - Therapeutic Hormone > C483 - Therapeutic Estrogen
同义名列表
1 个代谢物同义名
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Xinmei Jin, Lijun Ding, Depeng Xia, Peifang Chen. [Effects of acupoint catgut embedding combined with auricular point pressure on menopausal syndrome of liver-kidney deficiency type and estradiol].
Zhongguo zhen jiu = Chinese acupuncture & moxibustion.
2017 Aug; 37(8):836-839. doi:
10.13703/j.0255-2930.2017.08.010. [PMID: 29231343] - Xiao-Feng Li, Chun-Bo Lin, Fu-Rong Xie, Wei-Guo Liang, Jing Ji, Yuan Yang. Effects of Simvastatin and Combination of Simvastatin and Nylestriol on Bone Metabolism in Ovariectomized Rats.
American journal of therapeutics.
2016 Nov; 23(6):e1630-e1636. doi:
10.1097/mjt.0000000000000271. [PMID: 26171988] - Lifen Dai, Haiying Wu, Shan Yu, Hongbin Zhao, Lanjie Xue, Ming Xu, Zhiqiang Shen, Min Hu. Effects of OsteoKing on osteoporotic rabbits.
Molecular medicine reports.
2015 Jul; 12(1):1066-74. doi:
10.3892/mmr.2015.3551. [PMID: 25815520] - Yan-Ru Liu, Rong-Qing Huang, Bing-Kun Xiao, Jian-Yun Yang, Jun-Xing Dong. (1)H NMR metabolic profiling analysis offers evaluation of Nilestriol treatment in ovariectomised rats.
Molecular and cellular endocrinology.
2014 Apr; 387(1-2):19-34. doi:
10.1016/j.mce.2014.02.007. [PMID: 24565896] - Qing Miao, Jing-Ge Li, Shan Miao, Nan Hu, Jin Zhang, Song Zhang, Yan-Hua Xie, Jian-Bo Wang, Si-Wang Wang. The bone-protective effect of genistein in the animal model of bilateral ovariectomy: roles of phytoestrogens and PTH/PTHR1 against post-menopausal osteoporosis.
International journal of molecular sciences.
2012; 13(1):56-70. doi:
10.3390/ijms13010056. [PMID: 22312238] - H Nian, M-H Ma, S-S Nian, L-L Xu. Antiosteoporotic activity of icariin in ovariectomized rats.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2009 Apr; 16(4):320-6. doi:
10.1016/j.phymed.2008.12.006. [PMID: 19269147] - Zhao-Qiang Zhang, Hao-Yu Liu, Xi-Yi Liu. [Mechanism of the influence of CCE3 on bone mineral element metabolism in ovariectomized rats].
Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology.
2009 Feb; 25(1):129-32. doi:
NULL. [PMID: 21186636] - Hua Nian, Lu-Ping Qin, Qiao-Yan Zhang, Han-Chen Zheng, Yuan Yu, Bao-Kang Huang. Antiosteoporotic activity of Er-Xian Decoction, a traditional Chinese herbal formula, in ovariectomized rats.
Journal of ethnopharmacology.
2006 Nov; 108(1):96-102. doi:
10.1016/j.jep.2006.04.020. [PMID: 16765003] - Ke-ju Liu, Wen-jun Wang, Da-jin Li, Hui-fang Jin, Wen-jiang Zhou. Effect of Gengnianchun Recipe on bone mineral density, bone biomechanical parameters and serum lipid level in ovariectomized rats.
Chinese journal of integrative medicine.
2006 Jun; 12(2):132-6. doi:
10.1007/bf02857360. [PMID: 16800993] - Shi-Ping Liu, Er-Yuan Liao, Xian-Ping Wu, Xiang-Hang Luo, Huan-De Li, Ze-Neng Chen, Ru-Chun Dai, Rui-Yuan Sun, Xi-Jiu Liu. [Compound nylestriol tablet to prevent bone loss in osteoporotic rats].
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences.
2004 Aug; 29(4):405-9. doi:
NULL. [PMID: 16134591] - Kan Yang, Hong-wei Pan, Wei-hong Jiang. [Renal protective effect of nilestriol in aged women with hypertension].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University.
2003 Feb; 28(1):62-4. doi:
NULL. [PMID: 12934402] - Er-yuan Liao, Xiang-hang Luo, Wen-bo Wang, Xian-ping Wu, Hou-de Zhou, Ru-chun Dai, Hui-juan Liao, Chuan Yang. Effects of different nylestriol/levonorgestrel dosages on bone metabolism in female Sprague-Dawley rats with retinoic acid-induced osteoporosis.
Endocrine research.
2003 Feb; 29(1):23-42. doi:
10.1081/erc-120018674. [PMID: 12665316] - Ji-feng Wang, Jian-zhao Niu, Hua Li, Chi Zhang, Lian-qi Liu, Bao-hua Gao. [Effects of soy extract on lipid metabolism in ovariectomized rats].
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica.
2002 Apr; 27(4):285-8. doi:
NULL. [PMID: 12774376] - Q L Ma, H Y Zhou, M Sun. [Relationship between sex hormone levels and blood calcitonin gene-related peptide/endothelin-1 in postmenopausal women with coronary heart disease].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University.
2001 Apr; 26(2):146-8. doi:
NULL. [PMID: 12536650] - R Zhang, K Chen, D Lu. [Efficacy of Chinese recipes of replenishing kidney and activating blood circulation in female rats with osteoporosis induced by ovariectomy].
Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine.
1999 Oct; 19(10):607-9. doi:
NULL. [PMID: 11783176] - H Deng, H Zhou, M Sun. [Roles of sex hormones and oxygen free radical in coronary heart disease].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University.
1999; 24(4):343-6. doi:
NULL. [PMID: 12080642] - Q Ma, H Zhou, M Sun, S Wu. [Relationship between sex hormone levels and blood lipids/immunity in perimenopausal women].
Hunan yi ke da xue xue bao = Hunan yike daxue xuebao = Bulletin of Hunan Medical University.
1998; 23(5):461-4. doi:
NULL. [PMID: 10682561] - G J Cheng, J L Liu, Q Zhang, W Fan, H F Ye, Z Q Wang, H P Pan. Nylestriol replacement therapy in postmenopausal women. A three-year prospective study.
Chinese medical journal.
1993 Dec; 106(12):911-6. doi:
NULL. [PMID: 8198628] - G J Cheng. [Prospective study on nylestriol replacement therapy in postmenopausal women].
Zhonghua fu chan ke za zhi.
1993 Sep; 28(9):534-8, 569. doi:
NULL. [PMID: 8313746] - W Xie, Q Ziheng, G Lei, D Qiu, S Han, Z Han. [Anti-implantation action of nylestriol and its effect on uterine cytosol estrogen and progesterone receptor in rabbits].
Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao.
1993 Jun; 24(2):163-6. doi:
NULL. [PMID: 8244294] - S J Song. [Bone metabolism in postmenopausal women and after estrogen treatment].
Zhonghua fu chan ke za zhi.
1993 Feb; 28(2):79-81, 122. doi:
NULL. [PMID: 8344086] - G J Cheng, J L Liu, Q Zhang, H F Ye, Z Q Wang, H P Pan. Prospective double-blind study of CEE3 in peri- and postmenopausal women: effects on bone loss and lipoprotein lipids.
Chinese medical journal.
1992 Nov; 105(11):929-33. doi:
NULL. [PMID: 1304463]
