Emetine hydrochloride (BioDeep_00000641225)
代谢物信息卡片
Emetine Dihydrochloride
化学式: C29H42Cl2N2O4 (552.2521472)
中文名称: 盐酸吐根碱
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CCC1CN2CCC3=CC(=C(C=C3C2CC1CC4C5=CC(=C(C=C5CCN4)OC)OC)OC)OC.Cl.Cl
InChI: /m0../s1
描述信息
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000981 - Antiprotozoal Agents
D000890 - Anti-Infective Agents > D000977 - Antiparasitic Agents > D000871 - Anthelmintics
D018373 - Peripheral Nervous System Agents > D001337 - Autonomic Agents
D004791 - Enzyme Inhibitors > D011500 - Protein Synthesis Inhibitors
D005765 - Gastrointestinal Agents > D002400 - Cathartics
D005765 - Gastrointestinal Agents > D004639 - Emetics
D002491 - Central Nervous System Agents
C784 - Protein Synthesis Inhibitor
同义名列表
2 个代谢物同义名
数据库引用编号
7 个数据库交叉引用编号
- ChEBI: CHEBI:149551
- KEGGdrug: D03985
- PubChem: 3068143
- ChEMBL: CHEMBL493439
- MeSH: Emetine
- CAS: 83029-37-2
- CAS: 316-42-7
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Mohibullah Shah, Ramsha Yamin, Iqra Ahmad, Gang Wu, Zainab Jahangir, Amen Shamim, Haq Nawaz, Umar Nishan, Riaz Ullah, Essam A Ali, Sheheryar, Ke Chen. In-silico evaluation of natural alkaloids against the main protease and spike glycoprotein as potential therapeutic agents for SARS-CoV-2.
PloS one.
2024; 19(1):e0294769. doi:
10.1371/journal.pone.0294769. [PMID: 38175855] - Kun Zhang, Ke Wang, Chaoguo Zhang, Xiuli Teng, Dan Li, Mingwei Chen. Exploring the potential mechanism of emetine against coronavirus disease 2019 combined with lung adenocarcinoma: bioinformatics and molecular simulation analyses.
BMC cancer.
2022 Jun; 22(1):687. doi:
10.1186/s12885-022-09763-2. [PMID: 35733175] - Juhyeon Son, Sang Yeol Lee. Emetine exerts anticancer effects in U2OS human osteosarcoma cells via activation of p38 and inhibition of ERK, JNK, and β-catenin signaling pathways.
Journal of biochemical and molecular toxicology.
2021 Oct; 35(10):e22868. doi:
10.1002/jbt.22868. [PMID: 34338395] - Ming-Cheng Lee, Yin-Kai Chen, Jyy-Jih Tsai-Wu, Yih-Jen Hsu, Bor-Ru Lin. Zinc supplementation augments the suppressive effects of repurposed NF-κB inhibitors on ACE2 expression in human lung cell lines.
Life sciences.
2021 Sep; 280(?):119752. doi:
10.1016/j.lfs.2021.119752. [PMID: 34171382] - Ram Kumar, Mohammad Afsar, Nitin Khandelwal, Yogesh Chander, Thachamvally Riyesh, Ramesh Kumar Dedar, Baldev R Gulati, Yash Pal, Sanjay Barua, Bhupendra N Tripathi, Tanweer Hussain, Naveen Kumar. Emetine suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E.
Antiviral research.
2021 05; 189(?):105056. doi:
10.1016/j.antiviral.2021.105056. [PMID: 33711336] - Sayed S Sohrab, Mohd Suhail, Mohammad A Kamal, Esam I Azhar. Natural Products Homoharringtonine and Emetine Alkaloids as SARS-CoV-2 Treatment Options.
Current pharmaceutical design.
2021; 27(32):3444-3453. doi:
10.2174/1381612826666201210121858. [PMID: 33302852] - Dario Cattaneo, Dario Cattaneo, Cristina Gervasoni, Mario Corbellino, Massimo Galli, Agostino Riva, Cristina Gervasoni, Emilio Clementi, Emilio Clementi. Does lopinavir really inhibit SARS-CoV-2?.
Pharmacological research.
2020 08; 158(?):104898. doi:
10.1016/j.phrs.2020.104898. [PMID: 32438034] - Aleksandr Ianevski, Rouan Yao, Mona Høysæter Fenstad, Svetlana Biza, Eva Zusinaite, Tuuli Reisberg, Hilde Lysvand, Kirsti Løseth, Veslemøy Malm Landsem, Janne Fossum Malmring, Valentyn Oksenych, Sten Even Erlandsen, Per Arne Aas, Lars Hagen, Caroline H Pettersen, Tanel Tenson, Jan Egil Afset, Svein Arne Nordbø, Magnar Bjørås, Denis E Kainov. Potential Antiviral Options against SARS-CoV-2 Infection.
Viruses.
2020 06; 12(6):. doi:
10.3390/v12060642. [PMID: 32545799] - Ka-Tim Choy, Alvina Yin-Lam Wong, Prathanporn Kaewpreedee, Sin Fun Sia, Dongdong Chen, Kenrie Pui Yan Hui, Daniel Ka Wing Chu, Michael Chi Wai Chan, Peter Pak-Hang Cheung, Xuhui Huang, Malik Peiris, Hui-Ling Yen. Remdesivir, lopinavir, emetine, and homoharringtonine inhibit SARS-CoV-2 replication in vitro.
Antiviral research.
2020 06; 178(?):104786. doi:
10.1016/j.antiviral.2020.104786. [PMID: 32251767] - Ioanna A Anastasiou, Ioanna Eleftheriadou, Anastasios Tentolouris, Dimitrios Tsilingiris, Nikolaos Tentolouris. In Vitro Data of Current Therapies for SARS-CoV-2.
Current medicinal chemistry.
2020; 27(27):4542-4548. doi:
10.2174/0929867327666200513075430. [PMID: 32400323] - Petter I Andersen, Klara Krpina, Aleksandr Ianevski, Nastassia Shtaida, Eunji Jo, Jaewon Yang, Sandra Koit, Tanel Tenson, Veijo Hukkanen, Marit W Anthonsen, Magnar Bjoras, Magnus Evander, Marc P Windisch, Eva Zusinaite, Denis E Kainov. Novel Antiviral Activities of Obatoclax, Emetine, Niclosamide, Brequinar, and Homoharringtonine.
Viruses.
2019 10; 11(10):. doi:
10.3390/v11100964. [PMID: 31635418] - Sonja Krstin, Tamer Mohamed, Xiaojuan Wang, Michael Wink. How do the alkaloids emetine and homoharringtonine kill trypanosomes? An insight into their molecular modes of action.
Phytomedicine : international journal of phytotherapy and phytopharmacology.
2016 Dec; 23(14):1771-1777. doi:
10.1016/j.phymed.2016.10.008. [PMID: 27912879] - Rupkatha Mukhopadhyay, Sujayita Roy, Rajkumar Venkatadri, Yu-Pin Su, Wenjuan Ye, Elena Barnaeva, Lesley Mathews Griner, Noel Southall, Xin Hu, Amy Q Wang, Xin Xu, Andrés E Dulcey, Juan J Marugan, Marc Ferrer, Ravit Arav-Boger. Efficacy and Mechanism of Action of Low Dose Emetine against Human Cytomegalovirus.
PLoS pathogens.
2016 06; 12(6):e1005717. doi:
10.1371/journal.ppat.1005717. [PMID: 27336364] - Emmanuel S Akinboye, W Nathaniel Brennen, D Marc Rosen, Oladapo Bakare, Samuel R Denmeade. Iterative design of emetine-based prodrug targeting fibroblast activation protein (FAP) and dipeptidyl peptidase IV DPPIV using a tandem enzymatic activation strategy.
The Prostate.
2016 Jun; 76(8):703-14. doi:
10.1002/pros.23162. [PMID: 26835873] - Wenda Wu, Hui-Ren Zhou, Steven J Bursian, Jane E Link, James J Pestka. Emetic responses to T-2 toxin, HT-2 toxin and emetine correspond to plasma elevations of peptide YY3-36 and 5-hydroxytryptamine.
Archives of toxicology.
2016 Apr; 90(4):997-1007. doi:
10.1007/s00204-015-1508-7. [PMID: 25855062] - Zebalda D Bamji, Kareem N Washington, Emmanuel Akinboye, Oladapo Bakare, Yasmine M Kanaan, Robert L Copeland. Apoptotic Effects of Novel Dithiocarbamate Analogs of Emetine in Prostate Cancer Cell Lines.
Anticancer research.
2015 Sep; 35(9):4723-32. doi:
". [PMID: 26254362] - Ana Luiza Chaves Valadão, Celina Monteiro Abreu, Juliana Zanatta Dias, Pablo Arantes, Hugo Verli, Amilcar Tanuri, Renato Santana de Aguiar. Natural Plant Alkaloid (Emetine) Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity.
Molecules (Basel, Switzerland).
2015 Jun; 20(6):11474-89. doi:
10.3390/molecules200611474. [PMID: 26111177] - Koppany Visnyei, Hideyuki Onodera, Robert Damoiseaux, Kuniyasu Saigusa, Syuzanna Petrosyan, David De Vries, Denise Ferrari, Jonathan Saxe, Eduard H Panosyan, Michael Masterman-Smith, Jack Mottahedeh, Kenneth A Bradley, Jing Huang, Chiara Sabatti, Ichiro Nakano, Harley I Kornblum. A molecular screening approach to identify and characterize inhibitors of glioblastoma stem cells.
Molecular cancer therapeutics.
2011 Oct; 10(10):1818-28. doi:
10.1158/1535-7163.mct-11-0268. [PMID: 21859839] - Hye-Sik Kong, Sunmin Lee, Kristin Beebe, Bradley Scroggins, Gopal Gupta, Min-Jung Lee, Yun-Jin Jung, Jane Trepel, Leonard Neckers. Emetine promotes von Hippel-Lindau-independent degradation of hypoxia-inducible factor-2α in clear cell renal carcinoma.
Molecular pharmacology.
2010 Dec; 78(6):1072-8. doi:
10.1124/mol.110.066514. [PMID: 20813864] - Luiz Orlando de Oliveira, Ana Aparecida Bandini Rossi, Ernane Ronie Martins, Flávia Reis de Carvalho Batista, Roberta Santos Silva. Molecular phylogeography of Carapichea ipecacuanha, an amphitropical shrub that occurs in the understory of both semideciduous and evergreen forests.
Molecular ecology.
2010 Apr; 19(7):1410-22. doi:
10.1111/j.1365-294x.2010.04591.x. [PMID: 20298468] - S M Froscio, E Cannon, H M Lau, A R Humpage. Limited uptake of the cyanobacterial toxin cylindrospermopsin by Vero cells.
Toxicon : official journal of the International Society on Toxinology.
2009 Nov; 54(6):862-8. doi:
10.1016/j.toxicon.2009.06.019. [PMID: 19559040] - Paul Klausmeyer, Thomas G McCloud, Badarch Uranchimeg, Giovanni Melillo, Dominic A Scudiero, John H Cardellina, Robert H Shoemaker. Separation and SAR study of HIF-1alpha inhibitory tubulosines from Alangium cf. longiflorum.
Planta medica.
2008 Feb; 74(3):258-63. doi:
10.1055/s-2008-1034315. [PMID: 18302092] - Woo Jae Kim, Joon Hyun Kim, Sung Key Jang. Anti-inflammatory lipid mediator 15d-PGJ2 inhibits translation through inactivation of eIF4A.
The EMBO journal.
2007 Dec; 26(24):5020-32. doi:
10.1038/sj.emboj.7601920. [PMID: 18034160] - Tomas J Silber. Ipecac syrup abuse, morbidity, and mortality: isn't it time to repeal its over-the-counter status?.
The Journal of adolescent health : official publication of the Society for Adolescent Medicine.
2005 Sep; 37(3):256-60. doi:
10.1016/j.jadohealth.2004.08.022. [PMID: 16109351] - Omar A Itani, Kristyn L Cornish, Kang Z Liu, Christie P Thomas. Cycloheximide increases glucocorticoid-stimulated alpha -ENaC mRNA in collecting duct cells by p38 MAPK-dependent pathway.
American journal of physiology. Renal physiology.
2003 Apr; 284(4):F778-87. doi:
10.1152/ajprenal.00088.2002. [PMID: 12505861] - Masatomo Yamashita, Mamoru Yamashita, Junichi Azuma. Urinary excretion of ipecac alkaloids in human volunteers.
Veterinary and human toxicology.
2002 Oct; 44(5):257-9. doi:
. [PMID: 12361104] - Takayuki Asano, Kazuhisa Ishihara, Yoko Wakui, Toshihiko Yanagisawa, Masayuki Kimura, Hideo Kamei, Takemi Yoshida, Yukio Kuroiwa, Yuichi Fujii, Mamoru Yamashita, Takanori Kuramochi, Hiroki Tomisawa, Mitsuru Tateishi. Absorption, distribution and excretion of 3H-labeled cephaeline- and emetine-spiked ipecac syrup in rats.
European journal of drug metabolism and pharmacokinetics.
2002 Jan; 27(1):17-27. doi:
10.1007/bf03190401. [PMID: 11996323] - Takayuki Asano, Junko Watanabe, Chiharu Sadakane, Kazuhisa Ishihara, Kazuhiro Hirakura, Yoko Wakui, Toshihiko Yanagisawa, Masayuki Kimura, Hideo Kamei, Takemi Yoshida, Yuichi Fujii, Mamoru Yamashita. Biotransformation of the ipecac alkaloids cephaeline and emetine from ipecac syrup in rats.
European journal of drug metabolism and pharmacokinetics.
2002 Jan; 27(1):29-35. doi:
10.1007/bf03190402. [PMID: 11996324] - T Asano, C Sadakane, K Ishihara, T Yanagisawa, M Kimura, H Kamei. High-performance liquid chromatographic assay with fluorescence detection for the determination of cephaeline and emetine in human plasma and urine.
Journal of chromatography. B, Biomedical sciences and applications.
2001 Jun; 757(2):197-206. doi:
10.1016/s0378-4347(01)00170-0. [PMID: 11417863] - T Asano, H Kushida, C Sadakane, K Ishihara, Y Wakui, T Yanagisawa, M Kimura, H Kamei, T Yoshida. Metabolism of ipecac alkaloids cephaeline and emetine by human hepatic microsomal cytochrome P450s, and their inhibitory effects on P450 enzyme activities.
Biological & pharmaceutical bulletin.
2001 Jun; 24(6):678-82. doi:
10.1248/bpb.24.678. [PMID: 11411558] - E J Scharman, J M Hutzler, J G Rosencrance, T S Tracy. Single dose pharmacokinetics of syrup of ipecac.
Therapeutic drug monitoring.
2000 Oct; 22(5):566-73. doi:
10.1097/00007691-200010000-00011. [PMID: 11034262] - A Itoh, Y Ikuta, T Tanahashi, N Nagakura. Two Alangium alkaloids from Alangium lamarckii.
Journal of natural products.
2000 May; 63(5):723-5. doi:
10.1021/np0000163. [PMID: 10843602] - A Norlin, D L Baines, H G Folkesson. Role of endogenous cortisol in basal liquid clearance from distal air spaces in adult guinea-pigs.
The Journal of physiology.
1999 Aug; 519 Pt 1(?):261-72. doi:
10.1111/j.1469-7793.1999.0261o.x. [PMID: 10432356] - Rupinder Kaur, Anand K Bachhawat. The yeast multidrug resistance pump, Pdr5p, confers reduced drug resistance in erg mutants of Saccharomyces cerevisiae.
Microbiology (Reading, England).
1999 Apr; 145 ( Pt 4)(?):809-818. doi:
10.1099/13500872-145-4-809. [PMID: 10220160] - K N Rao, R K Bhattacharya, S R Venkatachalam. Thymidylate synthase activity and the cell growth are inhibited by the beta-carboline-benzoquinolizidine alkaloid deoxytubulosine.
Journal of biochemical and molecular toxicology.
1998; 12(3):167-73. doi:
10.1002/(sici)1099-0461(1998)12:3<167::aid-jbt5>3.0.co;2-j. [PMID: 9522276] - A M Gardner, F H Xu, C Fady, F J Jacoby, D C Duffey, Y Tu, A Lichtenstein. Apoptotic vs. nonapoptotic cytotoxicity induced by hydrogen peroxide.
Free radical biology & medicine.
1997; 22(1-2):73-83. doi:
10.1016/s0891-5849(96)00235-3. [PMID: 8958131] - M J Borgnia, G D Eytan, Y G Assaraf. Competition of hydrophobic peptides, cytotoxic drugs, and chemosensitizers on a common P-glycoprotein pharmacophore as revealed by its ATPase activity.
The Journal of biological chemistry.
1996 Feb; 271(6):3163-71. doi:
10.1074/jbc.271.6.3163. [PMID: 8621716] - T Koshiba, N Ballas, L M Wong, A Theologis. Transcriptional regulation of PS-IAA4/5 and PS-IAA6 early gene expression by indoleacetic acid and protein synthesis inhibitors in pea (Pisum sativum).
Journal of molecular biology.
1995 Oct; 253(3):396-413. doi:
10.1006/jmbi.1995.0562. [PMID: 7473723] - M Sengupta, O Sengupta. Correlation of biological activity (therapeutic and toxic) with solvochromic properties of metronidazole, emetine hydrochloride and diloxanide furoate.
Indian journal of biochemistry & biophysics.
1995 Oct; 32(5):302-7. doi:
. [PMID: 8713754] - B Ciapa, D Pesando, M Wilding, M Whitaker. Cell-cycle calcium transients driven by cyclic changes in inositol trisphosphate levels.
Nature.
1994 Apr; 368(6474):875-8. doi:
10.1038/368875a0. [PMID: 8159248] - D Thyagarajan, B J Day, J Wodak, B Gilligan, X Dennett. Emetine myopathy in a patient with an eating disorder.
The Medical journal of Australia.
1993 Dec; 159(11-12):757-60. doi:
10.5694/j.1326-5377.1993.tb141340.x. [PMID: 8264462] - T R Scott, M L Savage, I Olah. Plasma cells of the chicken Harderian gland.
Poultry science.
1993 Jul; 72(7):1273-9. doi:
10.3382/ps.0721273. [PMID: 8346152] - K Zahedi, A S Whitehead. Regulation of mouse serum amyloid P gene expression by cytokines in vitro.
Biochimica et biophysica acta.
1993 Mar; 1176(1-2):162-8. doi:
10.1016/0167-4889(93)90192-r. [PMID: 8452873] - M Sengupta, H Dutta, D K Pal, A U De, C Sengupta. Correlation of phospholipid loss in goat whole blood with solvochromic properties of antiamebics like emetine, metronidazole and diloxanide furoate.
Indian journal of experimental biology.
1993 Jan; 31(1):21-5. doi:
. [PMID: 8500812] - J C Samuelson, A Burke, J M Courval. Susceptibility of an emetine-resistant mutant of Entamoeba histolytica to multiple drugs and to channel blockers.
Antimicrobial agents and chemotherapy.
1992 Nov; 36(11):2392-7. doi:
10.1128/aac.36.11.2392. [PMID: 1283295] - M L Savage, I Oláh, T R Scott. Plasma cell proliferation in the chicken harderian gland.
Cell proliferation.
1992 Jul; 25(4):337-44. doi:
10.1111/j.1365-2184.1992.tb01444.x. [PMID: 1643190] - M P Kalapos, T Garzó, F Antoni, J Mandl. Accumulation of S-D-lactoylglutathione and transient decrease of glutathione level caused by methylglyoxal load in isolated hepatocytes.
Biochimica et biophysica acta.
1992 Jun; 1135(2):159-64. doi:
10.1016/0167-4889(92)90132-u. [PMID: 1616937] - P Duez, A Livaditis, P I Guissou, M Sawadogo, M Hanocq. Use of an Amoeba proteus model for in vitro cytotoxicity testing in phytochemical research. Application to Euphorbia hirta extracts.
Journal of ethnopharmacology.
1991 Sep; 34(2-3):235-46. doi:
10.1016/0378-8741(91)90042-c. [PMID: 1686625] - A Steinleitner, H Lambert, I Lauredo. Heterologous transplantation of activated murine peritoneal macrophages inhibits gamete interaction in vivo: a paradigm for endometriosis-associated subfertility.
Fertility and sterility.
1990 Oct; 54(4):725-9. doi:
10.1016/s0015-0282(16)53837-0. [PMID: 2209896] - I Oláh, F Antoni, I Csuka, J Törö. Effect of emetine on the plasma cell population of chicken's gland of Harder.
Acta physiologica Hungarica.
1990; 75(4):293-302. doi:
NULL. [PMID: 1706131] - P A Offit, H B Greenberg, K I Dudzik. Rotavirus-specific protein synthesis is not necessary for recognition of infected cells by virus-specific cytotoxic T lymphocytes.
Journal of virology.
1989 Aug; 63(8):3279-83. doi:
10.1128/jvi.63.8.3279-3283.1989. [PMID: 2545904] - W C Santangelo, J E Richey, L Rivera, J S Fordtran. Surreptitious ipecac administration simulating intestinal pseudo-obstruction.
Annals of internal medicine.
1989 Jun; 110(12):1031-2. doi:
10.7326/0003-4819-110-12-1031. [PMID: 2567141] - M F Lachman, R Romeo, R B McComb. Emetine identified in urine by HPLC, with fluorescence and ultraviolet/diode array detection, in a patient with cardiomyopathy.
Clinical chemistry.
1989 Mar; 35(3):499-502. doi:
. [PMID: 2920426] - R Overberg, G Chandrasena, C S Rupert. Radiation-induced recovery processes in cultured marsupial cells.
Mutation research.
1988 Sep; 194(2):83-92. doi:
10.1016/0167-8817(88)90010-7. [PMID: 3412365] - G D Burchard, D Mirelman. Entamoeba histolytica: virulence potential and sensitivity to metronidazole and emetine of four isolates possessing nonpathogenic zymodemes.
Experimental parasitology.
1988 Aug; 66(2):231-42. doi:
10.1016/0014-4894(88)90095-1. [PMID: 2899517] - K Ohno, T Sakai, M Fukushima, S Narumiya, M Fujiwara. Site and mechanism of growth inhibition by prostaglandins. IV. Effect of cyclopentenone prostaglandins on cell cycle progression of G1-enriched HeLa S3 cells.
The Journal of pharmacology and experimental therapeutics.
1988 Apr; 245(1):294-8. doi:
NULL. [PMID: 3361448] - A H Nielsen, K Poulsen. Evidence for a predominant renal secretion and clearance of inactive plasma renin, studied by in vivo inhibition of protein synthesis.
Journal of hypertension.
1988 Feb; 6(2):129-37. doi:
NULL. [PMID: 3280676] - K K Bhutani, G L Sharma, M Ali. Plant based antiamoebic drugs; Part I. Antiamoebic activity of phenanthroindolizidine alkaloids; common structural determinants of activity with emetine.
Planta medica.
1987 Dec; 53(6):532-6. doi:
10.1055/s-2006-962803. [PMID: 2895482] - W F Schwenk, E Rubanyi, M W Haymond. Effect of a protein synthetic inhibitor on in vivo estimates of protein synthesis in dogs.
The American journal of physiology.
1987 May; 252(5 Pt 1):E595-8. doi:
10.1152/ajpendo.1987.252.5.e595. [PMID: 3578509] - T Chintana, P Sucharit, V Mahakittikun, C Siripanth, W Suphadtanaphongs. In vitro studies on the sensitivity of local Entamoeba histolytica to anti-amoebic drugs.
The Southeast Asian journal of tropical medicine and public health.
1986 Dec; 17(4):591-4. doi:
. [PMID: 2883732] - F Galdiero, M A Tufano, F Rossi, W Filippelli, D De Santis, C Matera, L Berrino, E Marmo. Effect of Salmonella typhimurium porins on the cardiovascular and renal apparatus.
Journal of medicine.
1986; 17(5-6):285-97. doi:
NULL. [PMID: 3035043] - B G Kennedy, J E Lever. Transport by the (Na+,K+) ATPase: modulation by differentiation inducers and inhibition of protein synthesis in the MDCK kidney epithelial cell line.
Journal of cellular physiology.
1985 Jun; 123(3):410-6. doi:
10.1002/jcp.1041230317. [PMID: 2580848] - J Condomines, J M Reñe-Espinet, J C Espinos-Perez, F Vilardell. Percutaneous cholangiography in the diagnosis of hepatic fascioliasis.
The American journal of gastroenterology.
1985 May; 80(5):384-6. doi:
NULL. [PMID: 2859804] - A Asorey Carballeira, A Alguacil Muñoz, J M Guerra Vales, E Vilalta Castel. [Invasive amebiasis (II): Extra-intestinal forms and complications. Parasitological and serological diagnosis. Treatment].
Revista clinica espanola.
1985 Apr; 176(6):271-80. doi:
NULL. [PMID: 2860704] - M K Poirot, W M Schnitzlein, M E Reichmann. The requirement of protein synthesis for VSV inhibition of host cell RNA synthesis.
Virology.
1985 Jan; 140(1):91-101. doi:
10.1016/0042-6822(85)90448-9. [PMID: 2578240] - D M Moran, D J Crouch, B S Finkle. Absorption of ipecac alkaloids in emergency patients.
Annals of emergency medicine.
1984 Dec; 13(12):1100-2. doi:
10.1016/s0196-0644(84)80332-7. [PMID: 6150666] - J B Gibbs, G Brooker. Dissociation of RNA synthesis from the calcium requirement for serum-increased ornithine decarboxylase activity in rat glioma cells.
Biochimica et biophysica acta.
1984 Sep; 801(1):87-98. doi:
10.1016/0304-4165(84)90215-0. [PMID: 6432060] - C Agostini, M Di Segni. Effects of cimetidine and ranitidine on the "lipoperoxide" and lipid content of liver of rats treated with CCl4, colchicine, ethanol, ethionine and emetine.
Research communications in chemical pathology and pharmacology.
1984 Apr; 44(1):175-6. doi:
. [PMID: 6328599] - H Sugie, R Russin, M A Verity. Emetine myopathy: two case reports with pathobiochemical analysis.
Muscle & nerve.
1984 Jan; 7(1):54-9. doi:
10.1002/mus.880070109. [PMID: 6700630] - C Agostini, M Di Segni, A Negrini. Effects of various agents on the in vivo 'lipoperoxide' content of rat liver and kidney and on the 'lipoperoxide' and lipid content of liver slices.
Research communications in chemical pathology and pharmacology.
1983 Nov; 42(2):349-52. doi:
NULL. [PMID: 6658197] - Y F Liou, I H Hall, K H Lee. Antitumor agents LVI: the protein synthesis inhibition by genkwadaphnin and yuanhuacine of P-388 lymphocytic leukemia cells.
Journal of pharmaceutical sciences.
1982 Dec; 71(12):1340-4. doi:
10.1002/jps.2600711208. [PMID: 7153880] - Z Nambu, E Yokoyama. Protection with cycloheximide or emetine against pulmonary edema induced by ozone or nitrogen dioxide.
Sangyo igaku. Japanese journal of industrial health.
1982 Mar; 24(2):133-40. doi:
10.1539/joh1959.24.133. [PMID: 7131893] - E Walker, L H Chappell. Schistosoma mansoni: in vitro uptake and incorporation of glycine by adult worms.
Comparative biochemistry and physiology. B, Comparative biochemistry.
1982; 73(2):385-92. doi:
10.1016/0305-0491(82)90302-9. [PMID: 7172632] - D Stürchler, F Speiser, F Bogenmann, G Delmore. [Liver fascioliasis with unusual abscess formation. Case report].
Schweizerische medizinische Wochenschrift.
1981 Oct; 111(42):1578-82. doi:
NULL. [PMID: 6118949] - T Y Chang, J S Limanek, C C Chang. Evidence indicating that inactivation of 3-hydroxy-3-methylglutaryl coenzyme A reductase by low density lipoprotein or by 25-hydroxycholesterol requires mediator protein(s) with rapid turnover rate.
The Journal of biological chemistry.
1981 Jun; 256(12):6174-80. doi:
NULL. [PMID: 7240196] - J H Lipton, L Sachs. Characterization of macrophage- and granulocyte-inducing proteins for normal and leukemic myeloid cells produced by the Krebs ascites tumor.
Biochimica et biophysica acta.
1981 Apr; 673(4):552-69. doi:
10.1016/0304-4165(81)90486-4. [PMID: 7013820] - B Reichlin, K Gyr, M Giger, A L Blum. [Diagnosis of intestinal amebiasis].
Schweizerische medizinische Wochenschrift.
1981 Feb; 111(7):210-4. doi:
NULL. [PMID: 6111842] - C Aguirre Errasti, J Merino Angulo, M Flores Torres, A de los Rios. [Unusual forms of Fasciola hepatica infestation. Report of two cases (author's transl)].
Medicina clinica.
1981 Feb; 76(3):125-8. doi:
. [PMID: 6110812] - C Agostini, M Secchi, D Venturelli. 5'-Nucleotidase activity in liver homogenates of rats treated with CCl4, colchicine, cycloheximide, emetine, ethanol, ethionine and 5-fluorotryptophan.
Experientia.
1980 Sep; 36(9):1067-8. doi:
10.1007/bf01965973. [PMID: 6252041] - F Serafin, E Castañeda, S Díaz, O Palacios, G Gutiérrez-Trujillo. [Diagnostic and therapeutic evaluation of invasive intestinal amebiasis in children].
Archivos de investigacion medica.
1980; 11(1 Suppl):291-8. doi:
NULL. [PMID: 6258525] - S J Bannister, J Stevens, D Musson, L A Sternson. High-performance liquid chromatographic analysis of emetine after oxidative activation to a fluorescent product.
Journal of chromatography.
1979 Sep; 176(3):381-90. doi:
10.1016/s0021-9673(00)89456-x. [PMID: 546922] - G Oldham, T A Platts-Mills, D M Chalmers, A D Webster. A quantitative method for measuring in vitro synthesis of IgA and IgG by human rectal mucosa: studies on normal controls and patients with hypogammaglobulinaemia.
Immunology.
1979 Jul; 37(3):661-8. doi:
NULL. [PMID: 500122] - F J Serafín-Anaya, E Castañeda-Castañeira, S Díaz, O Palacios, G Gutiérrez-Trujillo. [Intestinal amebiasis in children II. Evaluation of various diagnostic technics and different therapeutic regimens].
Archivos de investigacion medica.
1978; 9 Suppl 1(?):371-4. doi:
NULL. [PMID: 697484] - F M Baccino, G Cecchini, F Palmucci, V Sverko, L Tessitore, M F Zuretti. Biphasic effects of translational inhibitors on liver tyrosine aminotransferase.
Biochimica et biophysica acta.
1977 Nov; 479(1):91-7. doi:
10.1016/0005-2787(77)90128-9. [PMID: 20956] - A Degrémont. [Biological diagnosis of malaria and amebiasis].
Schweizerische medizinische Wochenschrift.
1977 May; 107(18):641-2. doi:
NULL. [PMID: 194303] - S S Pong, S L Hong, L Levine. Prostaglandin production by methylcholanthrene-transformed mouse BALB/3T3. Requirement for protein synthesis.
The Journal of biological chemistry.
1977 Feb; 252(4):1408-13. doi:
. [PMID: 557039] - A D Ray, A K Chatterjee, S C Datta. Effects of emetine on serum proteins of rats fed diets of various protein levels.
Japanese journal of pharmacology.
1977 Feb; 27(1):165-7. doi:
10.1254/jjp.27.165. [PMID: 864876] - B R Jones, G A Ofosu. Cytotoxic effects of emetine hydrochloride in the kidney of Long-Evans rats.
Cytobios.
1977; 19(74):109-18. doi:
NULL. [PMID: 616384] - G T Werner, H Stickl. [Amebiasis 2].
Medizinische Klinik.
1976 Dec; 71(51-52):2254-9. doi:
NULL. [PMID: 13276] - B Emmerich, H Hoffman, V Erben, J Rastetter. Different susceptibility of protein synthesis to inhibitors of elongation in cell-free systems from plasma cell tumours and reticulocytes.
Biochimica et biophysica acta.
1976 Nov; 447(4):460-73. doi:
10.1016/0005-2787(76)90083-6. [PMID: 974138] - S Ramachandran, S S Shanmuganathan, N Nagarajah. Serum proteins in hepatic amoebiasis.
The Journal of tropical medicine and hygiene.
1976 May; 79(5):97-101. doi:
NULL. [PMID: 933232] - C Pareyre, N Farjaudon, G Deysson. [Kinetic study of the accumulation of anaphasic abnormalities in a synchronized population of meristematic root cells of Allium sativum L].
Comptes rendus des seances de la Societe de biologie et de ses filiales.
1976; 170(1):14-9. doi:
". [PMID: 134765] - A de Micheli, G A Medrano, A Villarreal, D Sodi-Pallares. [Protective effect of glucose-insulin-potassium solutions in myocardial damage caused by emetine].
Archivos del Instituto de Cardiologia de Mexico.
1975 Jul; 45(4):469-86. doi:
. [PMID: 1101837] - M Donaldson, D Heyneman, R Dempster, L Garcia. Epizootic of fatal amebiasis among exhibited snakes: epidemiologic, pathologic, and chemotherapeutic considerations.
American journal of veterinary research.
1975 Jun; 36(6):807-17. doi:
NULL. [PMID: 1147335] - J Chmielewski, B Jaremin, C Zwierz. Diagnostic and therapeutic management of cases of intestinal and parenteral amebiasis.
Materia medica Polona. Polish journal of medicine and pharmacy.
1975 Apr; 7(2):144-8. doi:
NULL. [PMID: 1142825] - B Emmerich, V Erben, H Hoffmann. [Proceedings: Susceptibility of endogenous mRNA translation to emetine and cycloheximide in cell free systems from plasma cell tumors, reticulocytes and liver].
Hoppe-Seyler's Zeitschrift fur physiologische Chemie.
1975 Mar; 356(3):228. doi:
NULL. [PMID: 1181254] - C Pareyre, G Deysson. Activity of tubulosine on the kinetics of root meristem cell population.
Cell and tissue kinetics.
1975 Jan; 8(1):67-79. doi:
10.1111/j.1365-2184.1975.tb01208.x. [PMID: 1116172] - E Gravela, G Bertone, G Poli. [Inhibitors of protein synthesis and hepatic steatosis: difference between cycloheximide, emetine and N-dimethylnitrosamine].
Bollettino della Societa italiana di biologia sperimentale.
1974 Oct; 50(20):1674-9. doi:
". [PMID: 4464015] - P Synek. [Renal excretion of emetine (author's transl)].
Casopis lekaru ceskych.
1974 Jul; 113(28):856-8. doi:
NULL. [PMID: 4849607]