(25S)-1alpha,25,26-trihydroxyvitamin D3 / (25S)-1alpha,25S,26-trihydroxycholecalciferol (BioDeep_00000637854)
代谢物信息卡片
化学式: C27H44O4 (432.3239)
中文名称:
谱图信息:
最多检出来源 () %
分子结构信息
SMILES: [C@@H]1(O)C(=C)/C(=C\C=C2\[C@]3([H])CC[C@@]([H])([C@@]3(C)CCC\2)[C@]([H])(C)CCC[C@@](O)(C)CO)/C[C@@H](O)C1
InChI: InChI=1S/C27H44O4/c1-18(7-5-13-26(3,31)17-28)23-11-12-24-20(8-6-14-27(23,24)4)9-10-21-15-22(29)16-25(30)19(21)2/h9-10,18,22-25,28-31H,2,5-8,11-17H2,1,3-4H3/b20-9+,21-10-/t18-,22-,23-,24+,25+,26+,27-/m1/s1
数据库引用编号
分类词条
相关代谢途径
Reactome()
BioCyc()
PlantCyc()
代谢反应
个相关的代谢反应过程信息。
Reactome()
BioCyc()
WikiPathways()
Plant Reactome()
INOH()
PlantCyc()
COVID-19 Disease Map()
PathBank()
PharmGKB()
个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Robert E Miller, Daniel Branstetter, Allison Armstrong, Bryan Kennedy, Jon Jones, Laine Cowan, Jeanine Bussiere, William C Dougall. Receptor activator of NF-kappa B ligand inhibition suppresses bone resorption and hypercalcemia but does not affect host immune responses to influenza infection.
Journal of immunology (Baltimore, Md. : 1950).
2007 Jul; 179(1):266-74. doi:
10.4049/jimmunol.179.1.266. [PMID: 17579046] - Luis M Esteban, Colette Fong, Deama Amr, Terrie-Anne Cock, Susan J Allison, Judith L Flanagan, Chris Liddle, John A Eisman, Edith M Gardiner. Promoter-, cell-, and ligand-specific transactivation responses of the VDRB1 isoform.
Biochemical and biophysical research communications.
2005 Aug; 334(1):9-15. doi:
10.1016/j.bbrc.2005.06.054. [PMID: 15992766] - M I Skliar, R L Boland, A Mourino, G Tojo. Isolation and identification of vitamin D3, 25-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3 and 1,24,25-trihydroxyvitamin D3 in Solanum malacoxylon incubated with ruminal fluid.
The Journal of steroid biochemistry and molecular biology.
1992 Dec; 43(7):677-82. doi:
10.1016/0960-0760(92)90293-r. [PMID: 1335278] - A Fournier, M Garabedian, I Grégoire, J L Sebert, A Pruna. [Vitamin D: metabolism and biological properties].
Annales de medecine interne.
1985; 136(2):154-63. doi:
NULL. [PMID: 3000251] - K Hove. Effects of 1 alpha-hydroxylated metabolites of cholecalciferol on intestinal radiocalcium absorption in goats.
The British journal of nutrition.
1984 Jan; 51(1):157-64. doi:
10.1079/bjn19840017. [PMID: 6546296] - R L Horst, K Hove, E T Littledike, T A Reinhardt, M R Uskokovic, J J Partridge. Plasma concentrations of 1,25-dihydroxyvitamin D, 1,24R,25-trihydroxyvitamin D3, and 2,25,26-trihydroxyvitamin D3 after their administration to dairy cows.
Journal of dairy science.
1983 Jul; 66(7):1455-60. doi:
10.3168/jds.s0022-0302(83)81959-6. [PMID: 6688433] - K Hove, R L Horst, E T Littledike. Effects of 1 alpha-hydroxyvitamin D3, 1,25-dihydroxyvitamin D3, 1,24,25-trihydroxyvitamin D3, and 1,25,26-trihydroxyvitamin D3 on mineral metabolism and 1,25-dihydroxyvitamin D concentrations in dairy cows.
Journal of dairy science.
1983 Jan; 66(1):59-66. doi:
10.3168/jds.s0022-0302(83)81753-6. [PMID: 6687602] - T A Reinhardt, J L Napoli, B Praminik, E T Littledike, D C Beitz, J J Partridge, M R Uskoković, R L Horst. 1 Alpha-25,26-trihydroxyvitamin D3: an in vivo and in vitro metabolite of vitamin D3.
Biochemistry.
1981 Oct; 20(21):6230-5. doi:
10.1021/bi00524a050. [PMID: 6272836] - Y Tanaka, H K Schnoes, C M Smith, H F DeLuca. 1,25,26-trihydroxyvitamin D3: isolation, identification, and biological activity.
Archives of biochemistry and biophysics.
1981 Aug; 210(1):104-9. doi:
10.1016/0003-9861(81)90169-7. [PMID: 6895295]
