Calcitroic acid (BioDeep_00000637649)
Main id: BioDeep_00000012153
代谢物信息卡片
化学式: C23H34O4 (374.24569640000004)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: CC(CC(=O)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C
InChI: InChI=1S/C23H34O4/c1-14(11-22(26)27)19-8-9-20-16(5-4-10-23(19,20)3)6-7-17-12-18(24)13-21(25)15(17)2/h6-7,14,18-21,24-25H,2,4-5,8-13H2,1,3H3,(H,26,27)/b16-6+,17-7-/t14-,18-,19-,20+,21+,23-/m1/s1
描述信息
D018977 - Micronutrients > D014815 - Vitamins > D004100 - Dihydroxycholecalciferols
D018977 - Micronutrients > D014815 - Vitamins > D006887 - Hydroxycholecalciferols
同义名列表
数据库引用编号
8 个数据库交叉引用编号
- ChEBI: CHEBI:47828
- KEGG: C18230
- PubChem: 9547273
- ChEMBL: CHEMBL3544529
- LipidMAPS: LMST03020013
- CAS: 71204-89-2
- PubChem: 103061412
- PDB-CCD: 2QI
分类词条
相关代谢途径
Reactome(4)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
1 个相关的物种来源信息
- 9606 - Homo sapiens: 10.1021/BI00430A051
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Martin Kaufmann, Corine Martineau, Alice Arabian, Mary Traynor, René St-Arnaud, Glenville Jones. Calcioic acid: In vivo detection and quantification of the terminal C24-oxidation product of 25-hydroxyvitamin D3 and related intermediates in serum of mice treated with 24,25-dihydroxyvitamin D3.
The Journal of steroid biochemistry and molecular biology.
2019 04; 188(?):23-28. doi:
10.1016/j.jsbmb.2018.12.001. [PMID: 30553931] - Olivia B Yu, Leggy A Arnold. Calcitroic Acid-A Review.
ACS chemical biology.
2016 10; 11(10):2665-2672. doi:
10.1021/acschembio.6b00569. [PMID: 27574921] - Maryam Goudarzi, Siddheshwar Chauthe, Steven J Strawn, Waylon M Weber, David J Brenner, Albert J Fornace. Quantitative Metabolomic Analysis of Urinary Citrulline and Calcitroic Acid in Mice after Exposure to Various Types of Ionizing Radiation.
International journal of molecular sciences.
2016 May; 17(5):. doi:
10.3390/ijms17050782. [PMID: 27213362] - R L Horst, J A Omdahl, S Reddy. Rat cytochrome P450C24 (CYP24) does not metabolize 1,25-dihydroxyvitamin D2 to calcitroic acid.
Journal of cellular biochemistry.
2003 Feb; 88(2):282-5. doi:
10.1002/jcb.10359. [PMID: 12520527] - D R Zimmerman, T A Reinhardt, R Kremer, D C Beitz, G S Reddy, R L Horst. Calcitroic acid is a major catabolic metabolite in the metabolism of 1 alpha-dihydroxyvitamin D(2).
Archives of biochemistry and biophysics.
2001 Aug; 392(1):14-22. doi:
10.1006/abbi.2001.2419. [PMID: 11469789] - G Makin, D Lohnes, V Byford, R Ray, G Jones. Target cell metabolism of 1,25-dihydroxyvitamin D3 to calcitroic acid. Evidence for a pathway in kidney and bone involving 24-oxidation.
The Biochemical journal.
1989 Aug; 262(1):173-80. doi:
10.1042/bj2620173. [PMID: 2818561] - G S Reddy, K Y Tserng. Calcitroic acid, end product of renal metabolism of 1,25-dihydroxyvitamin D3 through C-24 oxidation pathway.
Biochemistry.
1989 Feb; 28(4):1763-9. doi:
10.1021/bi00430a051. [PMID: 2719932] - R P Esvelt, H F De Luca. Calcitroic acid: biological activity and tissue distribution studies.
Archives of biochemistry and biophysics.
1981 Feb; 206(2):403-13. doi:
10.1016/0003-9861(81)90107-7. [PMID: 6261697] - H K Schnoes, H F DeLuca. Recent progress in vitamin D metabolism and the chemistry of vitamin D metabolites.
Federation proceedings.
1980 Aug; 39(10):2723-9. doi:
NULL. [PMID: 6250910]