Alfadolone (BioDeep_00000637586)
代谢物信息卡片
化学式: C21H32O4 (348.23)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: [C@@]12([H])CC[C@@]3([H])C[C@H](O)CC[C@]3(C)[C@@]1([H])C(=O)C[C@]1(C)[C@@H](C(=O)CO)CC[C@@]21[H]
InChI: InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13+,14-,15-,16+,19+,20-,21-/m0/s1
描述信息
同义名列表
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
| 亚细胞结构定位 | 关联基因列表 |
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文献列表
- Gustav Akk, Douglas F Covey, Alex S Evers, Joe Henry Steinbach, Charles F Zorumski, Steven Mennerick. The influence of the membrane on neurosteroid actions at GABA(A) receptors.
Psychoneuroendocrinology.
2009 Dec; 34 Suppl 1(?):S59-66. doi:
10.1016/j.psyneuen.2009.05.020. [PMID: 19541427] - J S Petersen, M Shalmi, S Christensen, K Haugan, N Lomholt. Comparison of the renal effects of six sedating agents in rats.
Physiology & behavior.
1996 Sep; 60(3):759-65. doi:
10.1016/0031-9384(96)00142-4. [PMID: 8873248] - I P Johnstone, B J Bancroft. The effects of different anesthetics on blood steroid concentrations in domestic tom-cats.
Australian veterinary journal.
1988 Dec; 65(12):382-5. doi:
10.1111/j.1751-0813.1988.tb14278.x. [PMID: 3223851] - M A Emanuele, J Tentler, L Kirsteins, D Reda, N V Emanuele, A M Lawrence. Anaesthesia with alphaxalone plus alphadolone acetate decreases serum concentrations of LH in castrated rats.
The Journal of endocrinology.
1987 Nov; 115(2):221-3. doi:
10.1677/joe.0.1150221. [PMID: 3437247] - R G Dyer, S Mansfield. Anaesthesia with alphaxalone plus alphadolone acetate blocks the oestrogen-stimulated LH surge and impairs pulsatile LH secretion in ovariectomized female rats.
The Journal of endocrinology.
1984 Jul; 102(1):27-31. doi:
10.1677/joe.0.1020027. [PMID: 6736851] - G O Stewart, G J Dobb, I A Craib. Clinical trial of continuous infusion of alphaxalone/alphadolone in intensive care patients.
Anaesthesia and intensive care.
1983 May; 11(2):107-12. doi:
10.1177/0310057x8301100203. [PMID: 6346940] - M Zachmann, D Tassinari, A Prader. Clinical and biochemical variability of congenital adrenal hyperplasia due to 11 beta-hydroxylase deficiency. A study of 25 patients.
The Journal of clinical endocrinology and metabolism.
1983 Feb; 56(2):222-9. doi:
10.1210/jcem-56-2-222. [PMID: 6296182] - J Descotes, P Tachon, A Laschi-Locquerie, J C Evreux. Adjuvancy of Cremophor Elo in rodents.
International archives of allergy and applied immunology.
1983; 72(3):287-8. doi:
10.1159/000234883. [PMID: 6618686] - A J Pateman. Sensitive gas chromatographic method for the determination of alphadolone in plasma.
Journal of chromatography.
1981 Nov; 226(1):213-8. doi:
10.1016/s0378-4347(00)84224-3. [PMID: 7320145] - J M Holly, D J Trafford, J W Sear, H L Makin. The in vivo metabolism of Althesin (alphaxalone + alphadolone acetate) in man.
The Journal of pharmacy and pharmacology.
1981 Jul; 33(7):427-33. doi:
10.1111/j.2042-7158.1981.tb13827.x. [PMID: 6115029]
