Saringosterol (BioDeep_00000637169)
代谢物信息卡片
化学式: C29H48O2 (428.36541079999995)
中文名称:
谱图信息:
最多检出来源 () 0%
分子结构信息
SMILES: C1[C@]2(C)[C@@]3([H])CC[C@]4(C)[C@@]([H])([C@]([H])(C)CCC(O)(C=C)C(C)C)CC[C@@]4([H])[C@]3([H])CC=C2C[C@@H](O)C1
InChI: InChI=1S/C29H48O2/c1-7-29(31,19(2)3)17-12-20(4)24-10-11-25-23-9-8-21-18-22(30)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-8,19-20,22-26,30-31H,1,9-18H2,2-6H3/t20-,22+,23+,24-,25+,26+,27+,28-,29?/m1/s1
数据库引用编号
分类词条
相关代谢途径
Reactome(0)
BioCyc(0)
PlantCyc(0)
代谢反应
0 个相关的代谢反应过程信息。
Reactome(0)
BioCyc(0)
WikiPathways(0)
Plant Reactome(0)
INOH(0)
PlantCyc(0)
COVID-19 Disease Map(0)
PathBank(0)
PharmGKB(0)
0 个相关的物种来源信息
在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：
- PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
- NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
- Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
- Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。
点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。
文献列表
- Dong-Yue Zhou, Yun-Hua Fu, Fang-Tong Li, Di Yang, Li-Na Wei, Hao Yue, Yu-Lin Dai, You-Jin Jeon. Treatment of Obese Zebrafish with Saringosterol Acetate through AMP Activated Protein Kinase Pathway.
Chemistry & biodiversity.
2022 Sep; 19(9):e202200495. doi:
10.1002/cbdv.202200495. [PMID: 35856892] - Xingyu Lu, Amila A Dissanayake, Chuqiao Xiao, Jie Gao, Mouming Zhao, Muraleedharan G Nair. The edible seaweed Laminaria japonica contains cholesterol analogues that inhibit lipid peroxidation and cyclooxygenase enzymes.
PloS one.
2022 ; 17(1):e0258980. doi:
10.1371/journal.pone.0258980. [PMID: 35085233] - Kenneth Vanbrabant, David Van Meel, Anja Kerksiek, Silvia Friedrichs, Marco Dubbeldam, Melissa Schepers, Na Zhan, Katharina Gutbrod, Peter Dörmann, Hong-Bing Liu, Monique T Mulder, Tim Vanmierlo, Dieter Lütjohann. 24(R, S)-Saringosterol - From artefact to a biological medical agent.
The Journal of steroid biochemistry and molecular biology.
2021 09; 212(?):105942. doi:
10.1016/j.jsbmb.2021.105942. [PMID: 34144153] - Ying Yan, Zhoumin Niu, Boyang Wang, Shangge Zhao, Chao Sun, Yuting Wu, Yuying Li, Hao Ying, Hongbing Liu. Saringosterol from Sargassum fusiforme Modulates Cholesterol Metabolism and Alleviates Atherosclerosis in ApoE-Deficient Mice.
Marine drugs.
2021 Aug; 19(9):. doi:
10.3390/md19090485. [PMID: 34564147] - Nikita Martens, Melissa Schepers, Na Zhan, Frank Leijten, Gardi Voortman, Assia Tiane, Ben Rombaut, Janne Poisquet, Nienke van de Sande, Anja Kerksiek, Folkert Kuipers, Johan W Jonker, Hongbing Liu, Dieter Lütjohann, Tim Vanmierlo, Monique T Mulder. 24(S)-Saringosterol Prevents Cognitive Decline in a Mouse Model for Alzheimer's Disease.
Marine drugs.
2021 Mar; 19(4):. doi:
10.3390/md19040190. [PMID: 33801706] - Jeroen Bogie, Cindy Hoeks, Melissa Schepers, Assia Tiane, Ann Cuypers, Frank Leijten, Yupyn Chintapakorn, Thiti Suttiyut, Surachai Pornpakakul, Dicky Struik, Anja Kerksiek, Hong-Bing Liu, Niels Hellings, Pilar Martinez-Martinez, Johan W Jonker, Ilse Dewachter, Eric Sijbrands, Jochen Walter, Jerome Hendriks, Albert Groen, Bart Staels, Dieter Lütjohann, Tim Vanmierlo, Monique Mulder. Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer's disease mouse model.
Scientific reports.
2019 03; 9(1):4908. doi:
10.1038/s41598-019-41399-4. [PMID: 30894635] - Jung A Lee, Young-Rak Cho, Seong Su Hong, Eun-Kyung Ahn. Anti-Obesity Activity of Saringosterol Isolated from Sargassum muticum (Yendo) Fensholt Extract in 3T3-L1 Cells.
Phytotherapy research : PTR.
2017 Nov; 31(11):1694-1701. doi:
10.1002/ptr.5892. [PMID: 28921681] - Zhen Chen, Jiao Liu, Zhifei Fu, Cheng Ye, Renshuai Zhang, Yiyun Song, Ying Zhang, Haihua Li, Hao Ying, Hongbing Liu. 24(S)-Saringosterol from edible marine seaweed Sargassum fusiforme is a novel selective LXRβ agonist.
Journal of agricultural and food chemistry.
2014 Jul; 62(26):6130-7. doi:
10.1021/jf500083r. [PMID: 24927286] - Sara Hoet, Luc Pieters, Giulio G Muccioli, Jean-Louis Habib-Jiwan, Fred R Opperdoes, Joëlle Quetin-Leclercq. Antitrypanosomal activity of triterpenoids and sterols from the leaves of Strychnos spinosa and related compounds.
Journal of natural products.
2007 Aug; 70(8):1360-3. doi:
10.1021/np070038q. [PMID: 17637068] - S Xu, Y Cen, L Cai, Y Li, S Xu. [Studies on the chemical components from Sargassum fusiform].
Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials.
2001 Jul; 24(7):491-2. doi:
". [PMID: 11668740]