Ceftizoxime (BioDeep_00000006371)

 

Secondary id: BioDeep_00001868100

human metabolite blood metabolite Chemicals and Drugs


代谢物信息卡片


(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

化学式: C13H13N5O5S2 (383.03580880000004)
中文名称: 头孢唑肟
谱图信息: 最多检出来源 () 0%

分子结构信息

SMILES: CON=C(C(=O)NC1C(=O)N2C(C(=O)O)=CCSC12)c1csc(=N)[nH]1
InChI: InChI=1S/C13H13N5O5S2/c1-23-17-7(5-4-25-13(14)15-5)9(19)16-8-10(20)18-6(12(21)22)2-3-24-11(8)18/h2,4,8,11H,3H2,1H3,(H2,14,15)(H,16,19)(H,21,22)/b17-7-/t8-,11-/m1/s1

描述信息

A semisynthetic cephalosporin antibiotic which can be administered intravenously or by suppository. The drug is highly resistant to a broad spectrum of beta-lactamases and is active against a wide range of both aerobic and anaerobic gram-positive and gram-negative organisms. It has few side effects and is reported to be safe and effective in aged patients and in patients with hematologic disorders. [PubChem]
J - Antiinfectives for systemic use > J01 - Antibacterials for systemic use > J01D - Other beta-lactam antibacterials > J01DD - Third-generation cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D002511 - Cephalosporins
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D047090 - beta-Lactams
D000890 - Anti-Infective Agents > D000900 - Anti-Bacterial Agents > D007769 - Lactams
C254 - Anti-Infective Agent > C258 - Antibiotic > C260 - Beta-Lactam Antibiotic

同义名列表

22 个代谢物同义名

(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid; 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylate; Syn-7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylic acid; Syn-7-(2-(2-amino-4-thiazolyl)-2-methoxyiminoacetamido)-3-cephem-4-carboxylate; GlaxoSmithKline brand OF cetizoxime sodium; Yamanouchi brand OF ceftizoxime sodium; Fujiwasa brand OF cetizoxime sodium; Salt, ceftizoxime monosodium; Monosodium salt, ceftizoxime; Ceftizoxime monosodium salt; Sodium, ceftizoxime; Ceftizoxime Sodium; SK And F 88373 2; SK And F 88373-2; SK And F 883732; Ceftizoximum; Ceftizoxima; ceftizoxime; CEFIZOX; CZX; Ceftizoxime



数据库引用编号

17 个数据库交叉引用编号

分类词条

相关代谢途径

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代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

1 个相关的物种来源信息

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有：

  • PubMed: 来源于PubMed文献库中的文献信息，我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表，这个列表按照代谢物同时出现的文献数量降序排序，取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘，得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序，取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中，存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称，可以跳转到相关代谢物的信息页面。



文献列表

  • Yifeng Zheng, Neng Wang, Shengqi Wang, Bo Pan, Bowen Yang, Juping Zhang, Xuan Wang, Zhiyu Wang. Cefoselis enhances breast cancer chemosensitivity by directly targeting GRP78/LRP5 signalling of cancer stem cells. Clinical and translational medicine. 2023 Feb; 13(2):e1119. doi: 10.1002/ctm2.1119. [PMID: 36808887]
  • Hannaneh Monirinasab, Mostafa Zakariazadeh, Havva Kohestani, Morteza Kouhestani, Farzaneh Fathi. Study of β-lactam-based drug interaction with albumin protein using optical, sensing, and docking methods. Journal of biological physics. 2022 06; 48(2):177-194. doi: 10.1007/s10867-021-09599-0. [PMID: 35094207]
  • Mingxing Sui, Nanxin Zheng, Da Xu, Yuhong Li, Yanhua Li, Shijun Pu, Meili Ji, Suxia Yang, Yutong Chen, Juan Huang, Youhua Zhu, Hanlan Lu, Li Zeng. Colistin sulfate for decontamination of preservation fluid in kidney transplantation to decrease the incidence of donor-derived infections caused by multidrug-resistant Gram-negative bacteria. Transplant infectious disease : an official journal of the Transplantation Society. 2022 Jun; 24(3):e13820. doi: 10.1111/tid.13820. [PMID: 35279926]
  • Li-Ping Han, Han-Yan Xiao, Li-Li Fang. A retrospective study of azithromycin and ceftizoxime for the management of children with Mycoplasma pneumoniae pneumonia. Medicine. 2021 Nov; 100(44):e27564. doi: 10.1097/md.0000000000027564. [PMID: 34871221]
  • André Birgy, Fouad Madhi, Camille Jung, Corinne Levy, Aurélie Cointe, Philippe Bidet, Claire Amaris Hobson, Stéphane Bechet, Elsa Sobral, Hoang Vuthien, Agnès Ferroni, Saïd Aberrane, Gaëlle Cuzon, Laetitia Beraud, Vincent Gajdos, Elise Launay, Didier Pinquier, Hervé Haas, Marie Desmarest, Marie-Aliette Dommergues, Robert Cohen, Stéphane Bonacorsi. Clavulanate combinations with mecillinam, cefixime or cefpodoxime against ESBL-producing Enterobacterales frequently associated with blaOXA-1 in a paediatric population with febrile urinary tract infections. The Journal of antimicrobial chemotherapy. 2021 10; 76(11):2839-2846. doi: 10.1093/jac/dkab289. [PMID: 34453533]
  • Rinku Buragohain, Tapas K Sar, Ujjwal Biswas, Indranil Samanta, Tapan K Mandal. Pharmacokinetics and Efficacy of Ceftriaxone in Staphylococcal Mastitis in Crossbred Cows Following Single Intravenous Administration. Current drug metabolism. 2021; 22(5):383-390. doi: 10.2174/1389200222666210210113641. [PMID: 33568029]
  • Rinku Buragohain, Tapas Kumar Sar, Indranil Samanta, Ujjwal Biswas, Tapan Kumar Mandal. Disposition of ceftizoxime in Staphylococcal mastitis in Indian crossbred cows. Veterinary journal (London, England : 1997). 2019 Mar; 245(?):12-14. doi: 10.1016/j.tvjl.2018.12.025. [PMID: 30819420]
  • Naseer Ahmed, Shazia Fatima, Muhammad Adnan Saeed, Muhammad Zia, Javaid Irfan Ullah. 99m Tc-Ceftizoxime: Synthesis, characterization and its use in diagnosis of diabetic foot osteomyelitis. Journal of medical imaging and radiation oncology. 2019 Feb; 63(1):61-68. doi: 10.1111/1754-9485.12841. [PMID: 30536554]
  • Laura De Petris, Ermanno Ruffini. Roultella ornithinolytica infection in infancy: a case of febrile urinary tract infection. CEN case reports. 2018 11; 7(2):234-236. doi: 10.1007/s13730-018-0333-2. [PMID: 29721836]
  • Tapas Kumar Sar, Indranil Samanta, Achintya Mahanti, Shabnam Akhtar, Jeevan Ranjan Dash. Potential of a polyherbal drug to prevent antimicrobial resistance in bacteria to antibiotics. Scientific reports. 2018 Jul; 8(1):10899. doi: 10.1038/s41598-018-28966-x. [PMID: 30022144]
  • Yan-Rong Ma, Yan Zhou, Jing Huang, Hong-Yan Qin, Pei Wang, Xin-An Wu. The urinary excretion of metformin, ceftizoxime and ofloxacin in high serum creatinine rats: Can creatinine predict renal tubular elimination?. Life sciences. 2018 Mar; 196(?):110-117. doi: 10.1016/j.lfs.2018.01.017. [PMID: 29355545]
  • Lubna Bashir, Muhammad Harris Shoaib, Shazia Naz, Rabia Ismail Yousuf, Sabahat Jabeen, Fozia Israr, Fahad Siddiqui. Development and validation of HPLC method for the determination of Cefpodoxime Proxetil in human plasma. Pakistan journal of pharmaceutical sciences. 2017 Sep; 30(5):1603-1607. doi: NULL. [PMID: 29084679]
  • Ali Mujtaba, Kanchan Kohli. Validated HPLC method for the pharmacokinetic study of oral extended-release cefpodoxime proxetil chitosan-alginate beads in rabbits. International journal of biological macromolecules. 2017 May; 98(?):111-116. doi: 10.1016/j.ijbiomac.2017.01.099. [PMID: 28137463]
  • Caizheng Li, Jiayu Sun, Jia Miao, Yongping Qin, Ying Wang, Rujia Yu, Yonghong Xiao. Using Monte Carlo simulation to determine optimal dosing regimen for cefetamet sodium for injection. Journal of chemotherapy (Florence, Italy). 2016 Jun; 28(3):172-9. doi: 10.1179/1973947814y.0000000214. [PMID: 25252727]
  • Lu Wang, Xin Zheng, Wen Zhong, Jia Chen, Ji Jiang, Pei Hu. Validation and Application of an LC-MS-MS Method for the Determination of Ceftizoxime in Human Serum and Urine. Journal of chromatographic science. 2016 May; 54(5):713-9. doi: 10.1093/chromsci/bmv243. [PMID: 26896348]
  • Beth Blane, Hayley J Brodrick, Theodore Gouliouris, Kirsty E Ambridge, Angela D Kidney, Catherine M Ludden, Direk Limmathurotsakul, M Estée Török, Sharon J Peacock. Comparison of 2 chromogenic media for the detection of extended-spectrum β-lactamase producing Enterobacteriaceae stool carriage in nursing home residents. Diagnostic microbiology and infectious disease. 2016 Mar; 84(3):181-3. doi: 10.1016/j.diagmicrobio.2015.11.008. [PMID: 26712266]
  • Ozlem Guneysel, Enes Suman, Tuba Cimilli Ozturk. TRIMETHOPRIM-SULFAMETHOXAZOLE RESISTANCE AND FOSFOMYCIN SUSCEPTIBILITY RATES IN UNCOMPLICATED URINARY TRACT INFECTIONS: TIME TO CHANGE THE ANTIMICROBIAL PREFERENCES. Acta clinica Croatica. 2016 Mar; 55(1):49-57. doi: 10.20471/acc.2016.55.01.8. [PMID: 27333718]
  • David A Bookstaver, Christopher M Bland, Miguel A Arroyo. Evaluation of cefazolin as a surrogate marker for cefpodoxime susceptibility for urinary tract isolates. Journal of medical microbiology. 2015 Oct; 64(10):1170-1173. doi: 10.1099/jmm.0.000142. [PMID: 26219948]
  • J A Lewis, P C L Moore, D L Arnold, L M Lawrance. Chromosomal ampC mutations in cefpodoxime-resistant, ESBL-negative uropathogenic Escherichia coli. British journal of biomedical science. 2015; 72(1):7-11. doi: 10.1080/09674845.2015.11666789. [PMID: 25906485]
  • Cüneyt Türkeş, Hakan Söyüt, Şükrü Beydemir. Human serum paraoxonase-1 (hPON1): in vitro inhibition effects of moxifloxacin hydrochloride, levofloxacin hemihidrate, cefepime hydrochloride, cefotaxime sodium and ceftizoxime sodium. Journal of enzyme inhibition and medicinal chemistry. 2015; 30(4):622-8. doi: 10.3109/14756366.2014.959511. [PMID: 25519764]
  • Bruce D Erickson, Christopher A Elkins, Lisa B Mullis, Thomas M Heinze, R Doug Wagner, Carl E Cerniglia. A metallo-β-lactamase is responsible for the degradation of ceftiofur by the bovine intestinal bacterium Bacillus cereus P41. Veterinary microbiology. 2014 Aug; 172(3-4):499-504. doi: 10.1016/j.vetmic.2014.05.032. [PMID: 24972871]
  • Cai-Zheng Li, Jia-Yu Sun, Ying Wang, Yong-Ping Qin, Jia Miao. [Phase I clinical trial on the safety of injectable cefetamet sodium with a single dose in healthy volunteers]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition. 2014 Jul; 45(4):637-41. doi: NULL. [PMID: 25286691]
  • Sameh Ahmed, Hanaa M Abdel-Wadood, Niveen A Mohamed. Highly sensitive and selective high-performance liquid chromatography method for bioequivalence study of cefpodoxime proxetil in rabbit plasma via fluorescence labeling of its active metabolite. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2013 Sep; 934(?):34-40. doi: 10.1016/j.jchromb.2013.06.036. [PMID: 23896427]
  • J-h Zhang, S Guo, M Xu, L-X Wu. A simply HPLC method for determination of cefpodoxime in Chinese volunteer and pharmacokinetic study. Drug research. 2013 Aug; 63(8):435-8. doi: 10.1055/s-0033-1345149. [PMID: 23677701]
  • Amrita Bajaj, Monica R P Rao, Ishwar Khole, Ghansham Munjapara. Self-nanoemulsifying drug delivery system of cefpodoxime proxetil containing tocopherol polyethylene glycol succinate. Drug development and industrial pharmacy. 2013 May; 39(5):635-45. doi: 10.3109/03639045.2012.683440. [PMID: 22564007]
  • Saurabh K Yadav, Bharati Agrawal, Rajendra N Goyal. AuNPs-poly-DAN modified pyrolytic graphite sensor for the determination of Cefpodoxime Proxetil in biological fluids. Talanta. 2013 Apr; 108(?):30-7. doi: 10.1016/j.talanta.2013.02.044. [PMID: 23601866]
  • Anil Dubala, Janaki Sankarachari Krishnan Nagarajan, Chandran Sathish Vimal, Renjith George. Simultaneous quantification of cefpodoxime proxetil and clavulanic acid in human plasma by LC-MS using solid phase extraction with application to pharmacokinetic studies. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2013 Mar; 921-922(?):49-55. doi: 10.1016/j.jchromb.2013.01.018. [PMID: 23434877]
  • Dirk R de Waart, Koen van de Wetering, Cindy Kunne, Suzanne Duijst, Coen C Paulusma, Ronald P J Oude Elferink. Oral availability of cefadroxil depends on ABCC3 and ABCC4. Drug metabolism and disposition: the biological fate of chemicals. 2012 Mar; 40(3):515-21. doi: 10.1124/dmd.111.041731. [PMID: 22166395]
  • Niveen A Mohamed, Hanaa M Abdel-Wadood, Sameh Ahmed. An efficient one-pot reaction for selective fluorimetric determination of cefpodoxime and its prodrug. Talanta. 2011 Sep; 85(4):2121-7. doi: 10.1016/j.talanta.2011.07.053. [PMID: 21872067]
  • Keumhan Noh, Eunyoung Kim, Wonku Kang. Quantitative determination of cefetamet in human plasma by liquid chromatography-mass spectrometry. Biomedical chromatography : BMC. 2011 Jul; 25(7):779-82. doi: 10.1002/bmc.1516. [PMID: 20845371]
  • V Kumar, R Madabushi, M B B Lucchesi, H Derendorf. Pharmacokinetics of cefpodoxime in plasma and subcutaneous fluid following oral administration of cefpodoxime proxetil in male beagle dogs. Journal of veterinary pharmacology and therapeutics. 2011 Apr; 34(2):130-5. doi: 10.1111/j.1365-2885.2010.01198.x. [PMID: 21395603]
  • Gönül Özel, Volkan Aslan, Gül Bahar Erdem, Mustafa Çağatay, Irfan Sencan, Ali Mert. [Comparison of oxacillin, cefoxitin, ceftizoxime, and moxalactam disk diffusion methods for detection of methicillin susceptibility in staphylococci]. Mikrobiyoloji bulteni. 2011 Apr; 45(2):258-65. doi: . [PMID: 21644068]
  • Momin A Mujeeb, Milind L Pardeshi. Pharmacokinetics of cefpodoxime proxetil with special reference to biochemical parameters, tissue residue, and spermatozoa motility in rats. Indian journal of medical sciences. 2011 Feb; 65(2):43-9. doi: . [PMID: 23196312]
  • Peymaneh Alizadeh Taheri, Hossein Eslamieh, Peyman Salamati. Is ceftizoxime an appropriate surrogate for amikacin in neonatal sepsis treatment? A randomized clinical trial. Acta medica Iranica. 2011; 49(8):499-503. doi: . [PMID: 22009803]
  • Mark G Papich, Jennifer L Davis, Amanda M Floerchinger. Pharmacokinetics, protein binding, and tissue distribution of orally administered cefpodoxime proxetil and cephalexin in dogs. American journal of veterinary research. 2010 Dec; 71(12):1484-91. doi: 10.2460/ajvr.71.12.1484. [PMID: 21118001]
  • Yuan Gao, Shuai Qian, Jianjun Zhang. Physicochemical and pharmacokinetic characterization of a spray-dried cefpodoxime proxetil nanosuspension. Chemical & pharmaceutical bulletin. 2010 Jul; 58(7):912-7. doi: 10.1248/cpb.58.912. [PMID: 20606336]
  • Emirhan Nemutlu, Sedef Kir, Doruk Katlan, M Sinan Beksaç. Simultaneous multiresponse optimization of an HPLC method to separate seven cephalosporins in plasma and amniotic fluid: application to validation and quantification of cefepime, cefixime and cefoperazone. Talanta. 2009 Nov; 80(1):117-26. doi: 10.1016/j.talanta.2009.06.034. [PMID: 19782200]
  • Manthena V S Varma, Bo Feng, R Scott Obach, Matthew D Troutman, Jonathan Chupka, Howard R Miller, Ayman El-Kattan. Physicochemical determinants of human renal clearance. Journal of medicinal chemistry. 2009 Aug; 52(15):4844-52. doi: 10.1021/jm900403j. [PMID: 19445515]
  • Aude Antignac, Alexander Tomasz. Reconstruction of the phenotypes of methicillin-resistant Staphylococcus aureus by replacement of the staphylococcal cassette chromosome mec with a plasmid-borne copy of Staphylococcus sciuri pbpD gene. Antimicrobial agents and chemotherapy. 2009 Feb; 53(2):435-41. doi: 10.1128/aac.01099-08. [PMID: 19015345]
  • R Scott Obach, Franco Lombardo, Nigel J Waters. Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals. 2008 Jul; 36(7):1385-405. doi: 10.1124/dmd.108.020479. [PMID: 18426954]
  • R Sharma, R P D Cooke, J G Ratcliffe. Detection of ESBL bacteria from clinical specimens: evaluation of a new selective medium. British journal of biomedical science. 2008; 65(4):191-4. doi: 10.1080/09674845.2008.11732827. [PMID: 19181037]
  • S A Brown, J F Boucher, V L Hubbard, M J Prough, T F Flook. The comparative plasma pharmacokinetics of intravenous cefpodoxime sodium and oral cefpodoxime proxetil in beagle dogs. Journal of veterinary pharmacology and therapeutics. 2007 Aug; 30(4):320-6. doi: 10.1111/j.1365-2885.2007.00873.x. [PMID: 17610405]
  • O Echeverria, L Alou, D Sevillano, N Gonzalez, M L Gomez-Lus, L Aguilar, J Prieto. Pharmacodynamics of simulated total versus free-drug serum concentrations of a low versus a high protein bound third-generation oral cephalosporin (Cefpodoxime versus cefditoren) against Streptococcus pneumoniae. Journal of chemotherapy (Florence, Italy). 2007 Jun; 19(3):288-94. doi: 10.1179/joc.2007.19.3.288. [PMID: 17594924]
  • Lei Ci, Hiroyuki Kusuhara, Masashi Adachi, John D Schuetz, Kenji Takeuchi, Yuichi Sugiyama. Involvement of MRP4 (ABCC4) in the luminal efflux of ceftizoxime and cefazolin in the kidney. Molecular pharmacology. 2007 Jun; 71(6):1591-7. doi: 10.1124/mol.106.031823. [PMID: 17344354]
  • Tetsuro Muratani, Tetsuro Matsumoto. Urinary tract infection caused by fluoroquinolone- and cephem-resistant Enterobacteriaceae. International journal of antimicrobial agents. 2006 Aug; 28 Suppl 1(?):S10-3. doi: 10.1016/j.ijantimicag.2006.05.009. [PMID: 16829056]
  • Kenichi Kaneko, Yoshinori Sato, Shu-ko Tokunaga, Sho-ko Tamaki, Ryoichi Okamoto, Matsuhisa Inoue. AmpC beta-lactamase-mediated cefpodoxime-resistant Escherichia coli isolated from faecal samples of healthy volunteers. The Journal of antimicrobial chemotherapy. 2006 Feb; 57(2):369-71. doi: 10.1093/jac/dki438. [PMID: 16338950]
  • V Gomes Barreto, G Rabiller, F Iglesias, V Soroa, F Tubau, M Roca, J Martín-Comín. [99mTc-ceftizoxime scintigraphy in normal rats and abscess induced rats]. Revista espanola de medicina nuclear. 2005 Sep; 24(5):312-8. doi: 10.1157/13079282. [PMID: 16194463]
  • Ping Liu, Richard Fuhrherr, Alistair I Webb, Bernd Obermann, Hartmut Derendorf. Tissue penetration of cefpodoxime into the skeletal muscle and lung in rats. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2005 Jul; 25(4-5):439-44. doi: 10.1016/j.ejps.2005.04.012. [PMID: 15905079]
  • Ping Liu, Markus Müller, Maria Grant, Bernd Obermann, Hartmut Derendorf. Tissue penetration of cefpodoxime and cefixime in healthy subjects. Journal of clinical pharmacology. 2005 May; 45(5):564-9. doi: 10.1177/0091270004273679. [PMID: 15831780]
  • A Di Filippo, R Cammelli, A Novelli, T Mazzei, F Tonelli, S Fallani, M I Cassetta, D Messeri, A R De Gaudio. Intraoperative positive fluid balance improves tissue diffusion of ceftizoxime. Chemotherapy. 2005 May; 51(2-3):51-6. doi: 10.1159/000085610. [PMID: 15870497]
  • Natalie A Carrillo, Steeve Giguère, Ronald R Gronwall, Murray P Brown, Kelly A Merritt, Jeffrey J O'Kelley. Disposition of orally administered cefpodoxime proxetil in foals and adult horses and minimum inhibitory concentration of the drug against common bacterial pathogens of horses. American journal of veterinary research. 2005 Jan; 66(1):30-5. doi: 10.2460/ajvr.2005.66.30. [PMID: 15691032]
  • Mara Aleksić, Milos Ilić, Vera Kapetanović. Adsorptive properties of cefpodoxime proxetil as a tool for a new method of its determination in urine. Journal of pharmaceutical and biomedical analysis. 2004 Nov; 36(4):899-903. doi: 10.1016/j.jpba.2004.08.035. [PMID: 15533687]
  • Yong-hong Xiao, Lei Gao, Yun Li, Yuan Lü, Jian Liu, Yan Liu. [Comparison of pharmacokinetics/pharmacodynamics of cefdinir, cefpodoxime proxetil and cefaclor against common bacteria of community acquired infections]. Zhonghua yi xue za zhi. 2004 Nov; 84(22):1867-71. doi: . [PMID: 15631795]
  • Georges Nicolaos, Sylvie Crauste-Manciet, Robert Farinotti, Denis Brossard. Improvement of cefpodoxime proxetil oral absorption in rats by an oil-in-water submicron emulsion. International journal of pharmaceutics. 2003 Sep; 263(1-2):165-71. doi: 10.1016/s0378-5173(03)00365-x. [PMID: 12954191]
  • Mara Aleksić, Ljiljana Milovanović, Vera Kapetanović. Adsorptive stripping voltammetric determination of cefetamet in human urine. Journal of pharmaceutical and biomedical analysis. 2003 Aug; 32(4-5):957-66. doi: 10.1016/s0731-7085(03)00197-3. [PMID: 12899982]
  • T Madhusudana Reddy, M Sreedhar, S Jayarama Reddy. Voltammetric behavior of cefixime and cefpodoxime proxetil and determination in pharmaceutical formulations and urine. Journal of pharmaceutical and biomedical analysis. 2003 Mar; 31(4):811-8. doi: 10.1016/s0731-7085(02)00721-5. [PMID: 12644208]
  • Ping Liu, Markus Müller, Maria Grant, Alistair I Webb, Bernd Obermann, Hartmut Derendorf. Interstitial tissue concentrations of cefpodoxime. The Journal of antimicrobial chemotherapy. 2002 Jul; 50 Suppl(?):19-22. doi: 10.1093/jac/dkf804. [PMID: 12077156]
  • Kunal Roy, Achintya Saha, Kakali De, Chandana Sengupta. Evaluation of probucol as suppressor of ceftizoxime induced lipid peroxidation. Acta poloniae pharmaceutica. 2002 May; 59(3):231-4. doi: ". [PMID: 12230252]
  • Toshihiro Hamada, Eisaku Ueta, Hiroyuki Kodama, Tokio Osaki. The excretion of cephem antibiotics into saliva is inversely associated with their plasma protein-binding activities. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology. 2002 Feb; 31(2):109-16. doi: 10.1046/j.0904-2512.2001.00015.x. [PMID: 11896833]
  • Akira Tsuji. Transporter-mediated Drug Interactions. Drug metabolism and pharmacokinetics. 2002; 17(4):253-74. doi: 10.2133/dmpk.17.253. [PMID: 15618677]
  • K Totsuka, K Shimizu, N Mori, T Sugihara, A Sakai, S Yamaji, Y Michisuji, Y Shinohara, A Kubo, H Tokuoka. Effect of antacid pretreatment on the pharmacokinetics of AS-924, a novel ester-type cephem antibiotic--comparison with cefteram-pivoxil. International journal of antimicrobial agents. 2001 Nov; 18(5):477-82. doi: 10.1016/s0924-8579(01)00445-9. [PMID: 11711264]
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