Stachyose (BioDeep_00000000631)

   

PANOMIX_OTCML-2023


代谢物信息卡片


(2S,3R,4S,5R,6R)-2-[[(2R,3R,4S,5R,6S)-6-[[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;tetrahydrate

化学式: C24H50O25 (738.2641)
中文名称: 水苏糖
谱图信息: 最多检出来源 Chinese Herbal Medicine(otcml) 78.4%

分子结构信息

SMILES: C(C1C(C(C(C(O1)OCC2C(C(C(C(O2)OCC3C(C(C(C(O3)OC4(C(C(C(O4)CO)O)O)CO)O)O)O)O)O)O)O)O)O)O.O.O.O.O
InChI: /m1..../s1

描述信息

Stachyose tetrahydrate is an oligosaccharide.
Stachyose tetrahydrate, a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine[1][2].
Stachyose tetrahydrate, a functional oligosaccharide, acts as a prebiotic. Stachyose tetrahydrate can prevent indirectly colon cancer cell growth by promoting the proliferation of probiotics or producing beneficial materials in the intestine[1][2].

同义名列表

8 个代谢物同义名

(2S,3R,4S,5R,6R)-2-[[(2R,3R,4S,5R,6S)-6-[[(2R,3S,4S,5R,6R)-6-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-3,4,5-trihydroxyoxan-2-yl]methoxy]-3,4,5-trihydroxyoxan-2-yl]methoxy]-6-(hydroxymethyl)oxane-3,4,5-triol;tetrahydrate; Stachyose (tetrahydrate); stachyose tetrahydrate; Stachyose hydrate(1:x); STACHYOSETETRAHYDRATE; stachyose hydrate; Stachyose; Stachyose



数据库引用编号

9 个数据库交叉引用编号

分类词条

相关代谢途径

Reactome(0)

BioCyc(0)

PlantCyc(0)

代谢反应

0 个相关的代谢反应过程信息。

Reactome(0)

BioCyc(0)

WikiPathways(0)

Plant Reactome(0)

INOH(0)

PlantCyc(0)

COVID-19 Disease Map(0)

PathBank(0)

PharmGKB(0)

在这里通过桑基图来展示出与当前的这个代谢物在我们的BioDeep知识库中具有相关联信息的其他代谢物。在这里进行关联的信息来源主要有:

  • PubMed: 来源于PubMed文献库中的文献信息,我们通过自然语言数据挖掘得到的在同一篇文献中被同时提及的相关代谢物列表,这个列表按照代谢物同时出现的文献数量降序排序,取前10个代谢物作为相关研究中关联性很高的代谢物集合展示在桑基图中。
  • NCBI Taxonomy: 通过文献数据挖掘,得到的代谢物物种来源信息关联。这个关联信息同样按照出现的次数降序排序,取前10个代谢物作为高关联度的代谢物集合展示在桑吉图上。
  • Chemical Taxonomy: 在物质分类上处于同一个分类集合中的其他代谢物
  • Chemical Reaction: 在化学反应过程中,存在为当前代谢物相关联的生化反应过程中的反应底物或者反应产物的关联代谢物信息。

点击图上的相关代谢物的名称,可以跳转到相关代谢物的信息页面。

亚细胞结构定位 关联基因列表


文献列表

  • Yuanyuan Li, Bingxue Liu, Xiaoxue Zhang, Yanjie Liu, Siying Wang, Shujun Li, Xiuhua Zhao. Lutein-stachyose (LS) amphiphilic oligosaccharide derivatives improve the oral bioavailability of lutein. Food chemistry. 2023 Aug; 418(?):136032. doi: 10.1016/j.foodchem.2023.136032. [PMID: 36996657]
  • Elisa Driesen, Wouter Saeys, Maurice De Proft, Arthur Lauwers, Wim Van den Ende. Far-Red Light Mediated Carbohydrate Concentration Changes in Leaves of Sweet Basil, a Stachyose Translocating Plant. International journal of molecular sciences. 2023 May; 24(9):. doi: 10.3390/ijms24098378. [PMID: 37176086]
  • Bing Hua, Mengying Zhang, Jinji Zhang, Haibo Dai, Zhiping Zhang, Minmin Miao. CsAGA1 and CsAGA2 Mediate RFO Hydrolysis in Partially Distinct Manner in Cucumber Fruits. International journal of molecular sciences. 2021 Dec; 22(24):. doi: 10.3390/ijms222413285. [PMID: 34948084]
  • Qian Li, Xinlei Tang, Jianghao Xu, Xingyuan Ren, Rui Wang, Songsong Jiang. Study on alleviation effect of stachyose on food allergy through TLR2/NF-κB signal pathway in a mouse model. Life sciences. 2021 Dec; 286(?):120038. doi: 10.1016/j.lfs.2021.120038. [PMID: 34653427]
  • Menglu Xi, Haixia Tang, Yan Zhang, Wupeng Ge, Ying Chen, Xiuxiu Cui. Microbiome-metabolomic analyses of the impacts of dietary stachyose on fecal microbiota and metabolites in infants intestinal microbiota-associated mice. Journal of the science of food and agriculture. 2021 Jun; 101(8):3336-3347. doi: 10.1002/jsfa.10963. [PMID: 33222240]
  • Pauline Okemo, Hao Long, Yen Cheng, Sagadevan Mundree, Brett Williams. Stachyose triggers apoptotic like cell death in drought sensitive but not resilient plants. Scientific reports. 2021 03; 11(1):7099. doi: 10.1038/s41598-021-86559-7. [PMID: 33782503]
  • Yingmei Wu, Yalong Lu, Daoyuan Ren, Xuefeng Chen, Xingbin Yang. Non-digestive stachyose enhances bioavailability of isoflavones for improving hyperlipidemia and hyperglycemia in mice fed with high fat diet. Journal of food and drug analysis. 2021 03; 29(1):87-97. doi: 10.38212/2224-6614.3078. [PMID: 35696221]
  • Menglu Xi, Jian Li, Guo Hao, Xiaopeng An, Yuxuan Song, Hong Wei, Wupeng Ge. Stachyose increases intestinal barrier through Akkermansia muciniphila and reduces gut inflammation in germ-free mice after human fecal transplantation. Food research international (Ottawa, Ont.). 2020 11; 137(?):109288. doi: 10.1016/j.foodres.2020.109288. [PMID: 33233042]
  • María Ciudad-Mulero, Virginia Fernández-Ruiz, Carmen Cuadrado, Claudia Arribas, Mercedes M Pedrosa, José De J Berrios, James Pan, Patricia Morales. Novel gluten-free formulations from lentil flours and nutritional yeast: Evaluation of extrusion effect on phytochemicals and non-nutritional factors. Food chemistry. 2020 Jun; 315(?):126175. doi: 10.1016/j.foodchem.2020.126175. [PMID: 31991254]
  • Xiaohua Qi, Qianqian Li, Jiatao Shen, Chunlu Qian, Xuewen Xu, Qiang Xu, Xuehao Chen. Sugar enhances waterlogging-induced adventitious root formation in cucumber by promoting auxin transport and signalling. Plant, cell & environment. 2020 06; 43(6):1545-1557. doi: 10.1111/pce.13738. [PMID: 32020637]
  • Cai-Na Li, Xing Wang, Lei Lei, Min-Zhi Liu, Rong-Cui Li, Su-Juan Sun, Shuai-Nan Liu, Yi Huan, Tian Zhou, Quan Liu, Hui Cao, Guo-Liang Bai, Yu-Wei Han, Zhu-Fang Shen. Berberine combined with stachyose induces better glycometabolism than berberine alone through modulating gut microbiota and fecal metabolomics in diabetic mice. Phytotherapy research : PTR. 2020 May; 34(5):1166-1174. doi: 10.1002/ptr.6588. [PMID: 31833107]
  • Liwen He, Feiran Zhang, Zhengyang Jian, Jiachen Sun, Jiamin Chen, Vuekhang Liapao, Qing He. Stachyose modulates gut microbiota and alleviates dextran sulfate sodium-induced acute colitis in mice. Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association. 2020 May; 26(3):153-159. doi: 10.4103/sjg.sjg_580_19. [PMID: 32270772]
  • Jinji Zhang, Hao Gu, Haibo Dai, Zhiping Zhang, Minmin Miao. Alternative polyadenylation of the stacyose synthase gene mediates source-sink regulation in cucumber. Journal of plant physiology. 2020 Feb; 245(?):153111. doi: 10.1016/j.jplph.2019.153111. [PMID: 31926460]
  • Li Liang, Guimei Liu, Guoyong Yu, Fuming Zhang, Robert J Linhardt, Quanhong Li. Urinary metabolomics analysis reveals the anti-diabetic effect of stachyose in high-fat diet/streptozotocin-induced type 2 diabetic rats. Carbohydrate polymers. 2020 Feb; 229(?):115534. doi: 10.1016/j.carbpol.2019.115534. [PMID: 31826396]
  • Rima Thapa, Militza Carrero-Colón, Katy M Rainey, Karen Hudson. TILLING by Sequencing: A Successful Approach to Identify Rare Alleles in Soybean Populations. Genes. 2019 12; 10(12):. doi: 10.3390/genes10121003. [PMID: 31817015]
  • Yueyue Liu, Ting Li, Aamina Alim, Daoyuan Ren, Yan Zhao, Xingbin Yang. Regulatory Effects of Stachyose on Colonic and Hepatic Inflammation, Gut Microbiota Dysbiosis, and Peripheral CD4+ T Cell Distribution Abnormality in High-Fat Diet-Fed Mice. Journal of agricultural and food chemistry. 2019 Oct; 67(42):11665-11674. doi: 10.1021/acs.jafc.9b04731. [PMID: 31588753]
  • Kambiz Morabbi Heravi, Hildegard Watzlawick, Josef Altenbuchner. The melREDCA Operon Encodes a Utilization System for the Raffinose Family of Oligosaccharides in Bacillus subtilis. Journal of bacteriology. 2019 08; 201(15):. doi: 10.1128/jb.00109-19. [PMID: 31138628]
  • Sondos Njoumi, Marie Josephe Amiot, Isabelle Rochette, Sihem Bellagha, Claire Mouquet-Rivier. Soaking and cooking modify the alpha-galacto-oligosaccharide and dietary fibre content in five Mediterranean legumes. International journal of food sciences and nutrition. 2019 Aug; 70(5):551-561. doi: 10.1080/09637486.2018.1544229. [PMID: 30614326]
  • Chaoyu Tian, Jiangang Yang, Yan Zeng, Tong Zhang, Yingbiao Zhou, Yan Men, Chun You, Yueming Zhu, Yuanxia Sun. Biosynthesis of Raffinose and Stachyose from Sucrose via an In Vitro Multienzyme System. Applied and environmental microbiology. 2019 01; 85(2):. doi: 10.1128/aem.02306-18. [PMID: 30389762]
  • Xin Li, Jing Du, Jinju Guo, Hongyun Wang, Si Ma, Jianguo Lü, Xiaolei Sui, Zhenxian Zhang. The functions of cucumber sucrose phosphate synthases 4 (CsSPS4) in carbon metabolism and transport in sucrose- and stachyose-transporting plants. Journal of plant physiology. 2018 Sep; 228(?):150-157. doi: 10.1016/j.jplph.2018.05.013. [PMID: 29913429]
  • Guimei Liu, Jia Bei, Li Liang, Guoyong Yu, Lu Li, Quanhong Li. Stachyose Improves Inflammation through Modulating Gut Microbiota of High-Fat Diet/Streptozotocin-Induced Type 2 Diabetes in Rats. Molecular nutrition & food research. 2018 03; 62(6):e1700954. doi: 10.1002/mnfr.201700954. [PMID: 29341443]
  • So Young Oh, So Youn Youn, Myeong Soo Park, Nam In Baek, Geun Eog Ji. Synthesis of Stachyobifiose Using Bifidobacterial α-Galactosidase Purified from Recombinant Escherichia coli. Journal of agricultural and food chemistry. 2018 Feb; 66(5):1184-1190. doi: 10.1021/acs.jafc.7b04703. [PMID: 29363955]
  • Jean Comtet, Robert Turgeon, Abraham D Stroock. Phloem Loading through Plasmodesmata: A Biophysical Analysis. Plant physiology. 2017 Oct; 175(2):904-915. doi: 10.1104/pp.16.01041. [PMID: 28794259]
  • Jianguo Lü, Xiaolei Sui, Si Ma, Xin Li, Huan Liu, Zhenxian Zhang. Suppression of cucumber stachyose synthase gene (CsSTS) inhibits phloem loading and reduces low temperature stress tolerance. Plant molecular biology. 2017 Sep; 95(1-2):1-15. doi: 10.1007/s11103-017-0621-9. [PMID: 28608281]
  • Ting Li, Xinshan Lu, Xingbin Yang. Evaluation of clinical safety and beneficial effects of stachyose-enriched α-galacto-oligosaccharides on gut microbiota and bowel function in humans. Food & function. 2017 Jan; 8(1):262-269. doi: 10.1039/c6fo01290f. [PMID: 28001151]
  • Yongfeng Ai, Karen A Cichy, Janice B Harte, James D Kelly, Perry K W Ng. Effects of extrusion cooking on the chemical composition and functional properties of dry common bean powders. Food chemistry. 2016 Nov; 211(?):538-45. doi: 10.1016/j.foodchem.2016.05.095. [PMID: 27283664]
  • Vasfiye Hazal Ozyurt, Semih Ötles. Effect of food processing on the physicochemical properties of dietary fibre. Acta scientiarum polonorum. Technologia alimentaria. 2016 Jul; 15(3):233-245. doi: 10.17306/j.afs.2016.3.23. [PMID: 28071023]
  • Wenfeng Li, Zhao Li, Xiao Han, Di Huang, Yalong Lu, Xingbin Yang. Enhancing the hepatic protective effect of genistein by oral administration with stachyose in mice with chronic high fructose diet consumption. Food & function. 2016 May; 7(5):2420-30. doi: 10.1039/c6fo00038j. [PMID: 27157892]
  • Yang Zhou, De-sheng Xu, Li Liu, Fu-rong Qiu, Jiong-liang Chen, Guang-lin Xu. A LC-MS/MS method for the determination of stachyose in rat plasma and its application to a pharmacokinetic study. Journal of pharmaceutical and biomedical analysis. 2016 May; 123(?):24-30. doi: 10.1016/j.jpba.2015.11.041. [PMID: 26859612]
  • Manu P Gangola, Sarita Jaiswal, Udhaya Kannan, Pooran M Gaur, Monica Båga, Ravindra N Chibbar. Galactinol synthase enzyme activity influences raffinose family oligosaccharides (RFO) accumulation in developing chickpea (Cicer arietinum L.) seeds. Phytochemistry. 2016 May; 125(?):88-98. doi: 10.1016/j.phytochem.2016.02.009. [PMID: 26953100]
  • Wenfeng Li, Di Huang, Anning Gao, Xingbin Yang. Stachyose increases absorption and hepatoprotective effect of tea polyphenols in high fructose-fed mice. Molecular nutrition & food research. 2016 Mar; 60(3):502-10. doi: 10.1002/mnfr.201500547. [PMID: 26582073]
  • Jun Yan, Songshan Shi, Hongwei Wang, Ruimin Liu, Ning Li, Yonglin Chen, Shunchun Wang. Neutral monosaccharide composition analysis of plant-derived oligo- and polysaccharides by high performance liquid chromatography. Carbohydrate polymers. 2016 Jan; 136(?):1273-80. doi: 10.1016/j.carbpol.2015.10.028. [PMID: 26572471]
  • Dan Qiu, Tri Vuong, Babu Valliyodan, Haiying Shi, Binhui Guo, J Grover Shannon, Henry T Nguyen. Identification and characterization of a stachyose synthase gene controlling reduced stachyose content in soybean. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik. 2015 Nov; 128(11):2167-76. doi: 10.1007/s00122-015-2575-0. [PMID: 26179337]
  • Sarah Findling, Klaus Zanger, Stephan Krueger, Gertrud Lohaus. Subcellular distribution of raffinose oligosaccharides and other metabolites in summer and winter leaves of Ajuga reptans (Lamiaceae). Planta. 2015 Jan; 241(1):229-41. doi: 10.1007/s00425-014-2183-2. [PMID: 25269399]
  • Ting Li, Xinshan Lu, Xingbin Yang. Stachyose-enriched α-galacto-oligosaccharides regulate gut microbiota and relieve constipation in mice. Journal of agricultural and food chemistry. 2013 Dec; 61(48):11825-31. doi: 10.1021/jf404160e. [PMID: 24245736]
  • Chunliu Zhuo, Ting Wang, Shaoyun Lu, Yaqing Zhao, Xiaoguang Li, Zhenfei Guo. A cold responsive galactinol synthase gene from Medicago falcata (MfGolS1) is induced by myo-inositol and confers multiple tolerances to abiotic stresses. Physiologia plantarum. 2013 Sep; 149(1):67-78. doi: 10.1111/ppl.12019. [PMID: 23253102]
  • Manu P Gangola, Yogendra P Khedikar, Pooran M Gaur, Monica Båga, Ravindra N Chibbar. Genotype and growing environment interaction shows a positive correlation between substrates of raffinose family oligosaccharides (RFO) biosynthesis and their accumulation in chickpea ( Cicer arietinum L.) seeds. Journal of agricultural and food chemistry. 2013 May; 61(20):4943-52. doi: 10.1021/jf3054033. [PMID: 23621405]
  • Raquel dos Santos, Rudy Vergauwen, Pieter Pacolet, Eveline Lescrinier, Wim Van den Ende. Manninotriose is a major carbohydrate in red deadnettle (Lamium purpureum, Lamiaceae). Annals of botany. 2013 Mar; 111(3):385-93. doi: 10.1093/aob/mcs288. [PMID: 23264235]
  • Katherine B Hagely, Debra Palmquist, Kristin D Bilyeu. Classification of distinct seed carbohydrate profiles in soybean. Journal of agricultural and food chemistry. 2013 Feb; 61(5):1105-11. doi: 10.1021/jf303985q. [PMID: 23317449]
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  • J W Ren, K M Chan, Patrick K K Lai, Clara B S Lau, H Yu, P C Leung, K P Fung, Walter F X Yu, C H Cho. Extracts from Radix Astragali and Radix Rehmanniae promote keratinocyte proliferation by regulating expression of growth factor receptors. Phytotherapy research : PTR. 2012 Oct; 26(10):1547-54. doi: 10.1002/ptr.4615. [PMID: 22359405]
  • Jérémy Pillet, Aurélie Egert, Philippe Pieri, Fatma Lecourieux, Christian Kappel, Justine Charon, Eric Gomès, Felix Keller, Serge Delrot, David Lecourieux. VvGOLS1 and VvHsfA2 are involved in the heat stress responses in grapevine berries. Plant & cell physiology. 2012 Oct; 53(10):1776-92. doi: 10.1093/pcp/pcs121. [PMID: 22952249]
  • Lidor Gil, Julius Ben-Ari, Robert Turgeon, Shmuel Wolf. Effect of CMV infection and high temperatures on the enzymes involved in raffinose family oligosaccharide biosynthesis in melon plants. Journal of plant physiology. 2012 Jul; 169(10):965-70. doi: 10.1016/j.jplph.2012.02.019. [PMID: 22575056]
  • Cankui Zhang, Xiyan Yu, Brian G Ayre, Robert Turgeon. The origin and composition of cucurbit 'phloem' exudate. Plant physiology. 2012 Apr; 158(4):1873-82. doi: 10.1104/pp.112.194431. [PMID: 22331409]
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